The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Attention-deficit/hyperactivity disorder: A preliminary diffusion tensor imaging study
Abstract
Background The purpose of this study was to explore whether there are white matter (WM) abnormalities in children with attention-deficit/hyperactivity disorder (ADHD) using diffusion tensor imaging. Based upon the literature, we predicted decreased fractional anisotropy (FA) findings in the frontal and cerebellar regions.Methods Eighteen patients with ADHD and 15 age- and gender-matched healthy volunteers received DTI assessments. Fractional anisotropy maps of WM were compared between groups with a voxelwise analysis after intersubject registration to Talairach space.Results Children with ADHD had decreased FA in areas that have been implicated in the pathophysiology of ADHD: right premotor, right striatal, right cerebral peduncle, left middle cerebellar peduncle, left cerebellum, and left parieto-occipital areas.Conclusions These preliminary data support the hypothesis that alterations in brain WM integrity in frontal and cerebellar regions occur in ADHD. The pattern of decreased FA might implicate the corticopontocerebellar circuit in the pathophysiology of ADHD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In children and adolescents, severity of ADHD symptoms was linked to decreased frontal and temporal grey matter, caudate and cerebellar volumes, [7] and decreased FA [15, 21, 26].”
From The brain anatomy of attention-deficit/hyperactivity disorder in young adults—a magnetic resonance imaging study (2017) · cites this paper as [21]
In the citing paper
“Some studies support that ADHD is associated with lifelong abnormal connectivity by showing that adults with ADHD have reduced connectivity in the orbito-medial prefrontal cortex, right anterior cingulate, right anterior corona radiata and the superior as well as inferior longitudinal fasciculus among other regions [18–21]”
From The brain anatomy of attention-deficit/hyperactivity disorder in young adults—a magnetic resonance imaging study (2017) · cites this paper as [21]
In the citing paper
“These findings, in part, corroborate previous results of white matter differences associated with symptoms severity [15, 16, 21, 26, 55].”
From The brain anatomy of attention-deficit/hyperactivity disorder in young adults—a magnetic resonance imaging study (2017) · cites this paper as [21]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
MR diffusion tensor spectroscopy and imaging
Basser, P. J., Mattiello, J., & LeBihan, D. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80775-1 · Cited by 5,970
Brain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552
Four Factor Index of Social Status [1975]
Hollingshead, A. B. (1975) · Cited by 5,151
Wechsler Intelligence Scale for Children
Miles-Mason, E. (2018) · Sage eBooks · doi:10.4135/9781483392271.n537 · Cited by 4,133
J Neuropsychiatry Clin Neurosci
Yudofsky, S. C., & Hales, R. E. (1992) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.4.4.359 · Cited by 3,818
The cerebellar cognitive affective syndrome
Schmahmann, J. (1998) · Brain · doi:10.1093/brain/121.4.561 · Cited by 3,230
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827
Tracking neuronal fiber pathways in the living human brain
Conturo, T. E., Lori, N. F., Cull, T. S., Akbudak, E., Snyder, A. Z., Shimony, J. S., McKinstry, R. C., Burton, H., & Raichle, M. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10422 · Cited by 1,774
Castellanos, F. X. (2002) · JAMA · doi:10.1001/jama.288.14.1740 · Cited by 1,646
Schmahmann, J. D. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2018.07.005 · Cited by 1,625
Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate
Kelly, R. M., & Strick, P. L. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-23-08432.2003 · Cited by 1,595
Basser, P. J. (1995) · NMR in Biomedicine · doi:10.1002/nbm.1940080707 · Cited by 1,526
Schmahmann, J. D. (2004) · Journal of Neuropsychiatry · doi:10.1176/jnp.16.3.367 · Cited by 1,490
DSM-III Disorders in Preadolescent Children
Anderson, J. C. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800130081010 · Cited by 1,466
Wechsler Intelligence Scale for Children
Park, S. E., & Demakis, G. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-28099-8_1035-1 · Cited by 1,327
Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system.
Moseley, M. E., Cohen, Y., Kucharczyk, J. R., Mintorovitch, J., Asgari, H. S., Wendland, M. F., Tsuruda, J. S., & Norman, D. M. (1990) · Radiology · doi:10.1148/radiology.176.2.2367658 · Cited by 1,132
Cerebrocerebellar communication systems.
Allen, G. I., & Tsukahara, N. (1974) · Physiological Reviews · doi:10.1152/physrev.1974.54.4.957 · Cited by 1,084
Cerebellar Projections to the Prefrontal Cortex of the Primate
Middleton, F. A., & Strick, P. L. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-02-00700.2001 · Cited by 1,034
Cerebral Glucose Metabolism in Adults with Hyperactivity of Childhood Onset
Zametkin, A. J., NORDAHL, T. E., Gross, M., King, A. C., Semple, W. E., Rumsey, J. M., Hamburger, S., & Cohen, R. M. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011153232001 · Cited by 975
The Frontal Lobes and Voluntary Action
Passingham, R. (1993) · doi:10.1093/oso/9780198521853.001.0001 · Cited by 970
CASEY, B. J., CASTELLANOS, F. X., GIEDD, J. N., MARSH, W. L., HAMBURGER, S. D., SCHUBERT, A. B., VAUSS, Y. C., VAITUZIS, A. C., DICKSTEIN, D. P., SARFATTI, S. E., et al. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199703000-00016 · Cited by 800
Schmahmann, J. D., & Pandya, D. N. (1997) · International Review of Neurobiology · doi:10.1016/s0074-7742(08)60346-3 · Cited by 774
Neuropsychological consequences of cerebellar tumour resection in children
Levisohn, L., Cronin‐Golomb, A., & Schmahmann, J. D. (2000) · Brain · doi:10.1093/brain/123.5.1041 · Cited by 773
Filipek, P. A., Semrud-Clikeman, M., Steingard, R. J., Renshaw, P. F., Kennedy, D. N., & Biederman, J. (1997) · Neurology · doi:10.1212/wnl.48.3.589 · Cited by 732
Frontal-subcortical circuits and neuropsychiatric disorders
Mega, M. S., & Cummings, J. L. (1994) · Journal of Neuropsychiatry · doi:10.1176/jnp.6.4.358 · Cited by 726
Estimnates of the Prevalence of Childhood Maladjustment in a Community Survey in Puerto Rico
Bird, H. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360068010 · Cited by 716
An unfolded map of the cerebellar dentate nucleus and its projections to the cerebral cortex
Dum, R. P., & Strick, P. L. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00626.2002 · Cited by 684
Development of Cortical Circuitry and Cognitive Function
Goldman-Rakic, P. S. (1987) · Child Development · doi:10.2307/1130201 · Cited by 655
Motor areas in the frontal lobe of the primate
DUM, R., & STRICK, P. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00929-0 · Cited by 653
Differential patterns of striatal activation in young children with and without ADHD
Durston, S., Tottenham, N. T., Thomas, K. M., Davidson, M. C., Eigsti, I.-M., Yang, Y., Ulug, A. M., & Casey, B. J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01904-2 · Cited by 619
Brain Morphology in Developmental Dyslexia and Attention Deficit Disorder/Hyperactivity
Hynd, G. W., Semrud‐Clikeman, M., Lorys, A. R., Novey, E. S., & Eliopulos, D. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530080107018 · Cited by 612
Tannock, R. (1998) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00304 · Cited by 604
A simplified method to measure the diffusion tensor from seven MR images
Basser, P. J., & Pierpaoli, C. M. (1998) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910390610 · Cited by 584
Cerebellum in attention-deficit hyperactivity disorder: A morphometric MRI study
Berquin, P. C., Giedd, J. N., Jacobsen, L. K., Hamburger, S. D., Krain, A. L., Rapoport, J. L., & Castellanos, F. X. (1998) · Neurology · doi:10.1212/wnl.50.4.1087 · Cited by 564
THE CORTICOPONTINE PROJECTION IN THE RHESUS MONKEY ORIGIN AND PRINCIPLES OF ORGANIZATION
Brodal, P. (1978) · Brain · doi:10.1093/brain/101.2.251 · Cited by 481
Hubl, D., Koenig, T. W., Strik, W. K., Federspiel, A., Kreis, R., Boesch, C., Maier, S. E., Schroth, G., Lövblad, K., & Dierks, T. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.658 · Cited by 466
Baumgaertel, A., Wolraich, M. L., & Dietrich, M. S. (1995) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199505000-00015 · Cited by 392
Smaller prefrontal and premotor volumes in boys with attention-deficit/hyperactivity disorder
Mostofsky, S. H., Cooper, K. L., Kates, W. R., Denckla, M. B., & Kaufmann, W. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01412-9 · Cited by 379
Makris, N., Worth, A. J., Papadimitriou, G., Stakes, J. W., Caviness, V. S., Kennedy, D. N., Pandya, D. Ν., Kaplan, E., Sorensen, A. G., Wu, O., et al. (1997) · Annals of Neurology · doi:10.1002/ana.410420617 · Cited by 377
Tannock, R. (1998) · Journal of Child Psychology and Psychiatry · doi:10.1017/s0021963097001777 · Cited by 369
A Fully Automatic Multimodality Image Registration Algorithm
Ardekani, B. A., Braun, M., Hutton, B. F., Kanno, I., & Iida, H. (1995) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199507000-00022 · Cited by 310
Self-citationA Possible Pathophysiologic Substrate of Attention Deficit Hyperactivity Disorder
Heilman, K. M., Voeller, K. K. S., & Nadeau, S. E. (1991) · Journal of Child Neurology · doi:10.1177/0883073891006001s09 · Cited by 267
Gilman, S., Bloedel, J. R., & Lechtenberg, R. J. (1981) · F.A. Davis Co. eBooks · Cited by 250
Ardekani, B. A., Stephen Guckemus, A., Bachman, A. H., Hoptman, M. J., Michelle Wojtaszek, A., & Nierenberg, J. J. (2004) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.07.014 · Cited by 243
Self-citationSense of time in children with ADHD: Effects of duration, distraction, and stimulant medication
Barkley, R. A., KOPLOWITZ, S., ANDERSON, T., & McMurray, M. B. (1997) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617797003597 · Cited by 239
Semrud‐Clikeman, M., Steingard, R. J., Filipek, P. A., Biederman, J., Bekken, K., & Renshaw, P. F. (2000) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200004000-00017 · Cited by 233
OVERMEYER, S., BULLMORE, E. T., SUCKLING, J., SIMMONS, A., WILLIAMS, S. C. R., SANTOSH, P. J., & TAYLOR, E. (2001) · Psychological Medicine · doi:10.1017/s0033291701004706 · Cited by 209
Szeszko, P. R., Ardekani, B. A., Ashtari, M., Kumra, S., Robinson, D. G., Sevy, S. M., Gunduz‐Bruce, H., Malhotra, A. K., Kane, J. M., Bilder, R. M., et al. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.3.602 · Cited by 191
Self-citationEvaluation of ADHD Typology in Three Contrasting Samples: A Latent Class Approach
Neuman, R. J., Todd, R. D., Heath, A. C., Reich, W., Hudziak, J. J., Bucholz, K. K., Madden, P. A. F., Begleiter, H., Bernice Porjesz, A., Samuel Kuperman, C., et al. (1999) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199901000-00016 · Cited by 162
Motor projections to the basis pontis in rhesus monkey
Schmahmann, J. D., Rosene, D. L., & Pandya, D. N. (2004) · Journal of Comparative Neurology · doi:10.1002/cne.20286 · Cited by 146
Activation of the Supplementary Motor Area (SMA) during Performance of Visually Guided Movements
Picard, N. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.9.977 · Cited by 132
Attention Deficit/Hyperactivity Disorder as a Right Hemisphere Syndrome
Stefanatos, G. A., & Wasserstein, J. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05779.x · Cited by 115
Stefanatos, G. A., & Wasserstein, J. (2001) · PubMed · Cited by 102
Brain morphometry in Tourette's syndrome
Castellanos, F. X., Giedd, J. N., Hamburger, S. D., Marsh, W., & Rapoport, J. L. (1996) · Neurology · doi:10.1212/wnl.47.6.1581 · Cited by 78
A short form of the WISC--III for clinical use.
Donders, J. (1997) · Psychological Assessment · doi:10.1037/1040-3590.9.1.15 · Cited by 65
Stimulating research on motor cortex
Strick, P. L. (2002) · Nature Neuroscience · doi:10.1038/nn0802-714 · Cited by 62
Single-neuron activity in the human supplementary motor area underlying preparation for action
Amador, N., & Fried, I. (2004) · Journal of neurosurgery · doi:10.3171/jns.2004.100.2.0250 · Cited by 55
The Kiddie-Sads-Present and Lifetime Version
Mattos, P., & Rohde, L. A. (2007) · Journal of Attention Disorders · doi:10.1177/1087054707305152 · Cited by 39
Flagged first, then by citations
Cited by
Sorted by citations
Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI
Yu-Feng, Z., Yong, H., Chao-Zhe, Z., Qing-Jiu, C., Man-Qiu, S., Meng, L., Li-Xia, T., Tian-Zi, J., & Yu-Feng, W. (2007) · Brain and Development · doi:10.1016/j.braindev.2006.07.002 · Cited by 2,660
Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder
Valera, E. M., Faraone, S. V., Murray, K. E., & Seidman, L. J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.06.011 · Cited by 891
Konrad, K., & Eickhoff, S. B. (2010) · Human Brain Mapping · doi:10.1002/hbm.21058 · Cited by 670
Cubillo, A., Halari, R., Smith, A., Taylor, E., & Rubia, K. (2012) · Cortex · doi:10.1016/j.cortex.2011.04.007 · Cited by 520
Tripp, G., & Wickens, J. R. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.07.026 · Cited by 492
Metadata
- Authors
- Ashtari, M., Kumra, S., Bhaskar, S. L., Clarke, T., Thaden, E., Cervellione, K. L., Rhinewine, J., Kane, J. M., Adesman, A., Milanaik, R., Maytal, J., Diamond, A., Szeszko, P., & Ardekani, B. A.
- Affiliations
- Northwell Health (US)
- Albert Einstein College of Medicine (US)
- Schneider Children's Hospital (US)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Ashtari, Manzar
- ORCID
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 57
- Issue
- 5
- Pages
- 448-455
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2155922385
- Cited by
- 295
- References
- 61
- Citations by year
- 2025: 5 · 2024: 6 · 2023: 5 · 2022: 7 · 2021: 7 · 2020: 7 · 2019: 6 · 2018: 8 · 2017: 11 · 2016: 11 · 2015: 21 · 2014: 24 · 2013: 24 · 2012: 21
- FWCI
- 10.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (K01MH001990, MH-070612, MH01990, K23MH064556, MH 64556, R03MH070612)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- attention deficit hyperactivity disorder, white matter abnormalities, fractional anisotropy, diffusion tensor imaging, children, cerebellum, frontal lobe, striatum
- MeSH terms
- Attention Deficit Disorder with Hyperactivity, Brain Mapping, Cerebellum, Child, Female, Frontal Lobe, Humans, Image Processing, Computer-Assisted, Male, Case-Control Studies, Anisotropy, Diffusion Magnetic Resonance Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
