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Cited by 146Motor Control and AdaptationAdvanced Neuroimaging Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Motor projections to the basis pontis in rhesus monkey

Schmahmann, Jeremy D., Rosene, Douglas L., Pandya, Deepak N.·2004·Journal of Comparative Neurology
DOI 10.1002/cne.20286
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Abstract

Motor corticopontine studies suggest that the pons is topographically organized, but details remain unresolved. We used physiological mapping in rhesus monkey to define subregions in precentral motor cortex (M1), injected isotope tracers into M1 and the supplementary motor area (SMA), and studied projections to the basis pontis. Labeled fibers descend in the internal capsule (SMA in anterior limb and genu; M1 in posterior limb) and traverse the midsection of the cerebral peduncle, where SMA fibers are medial, and face, arm, and leg fibers are progressively lateral. Each motor region has unique terminations in the ipsilateral basis pontis and nucleus reticularis tegmenti pontis. Projections are topographically organized, preferentially in the caudal half of the pons, situated in close proximity to traversing corticofugal fibers. In nuclei that receive multiple inputs, terminations appear to interdigitate. Projections from the SMA‐face region are most medial and include the median pontine nucleus. M1‐face projections are also medial but are lateral to those from SMA‐face. Hand projections are in medially placed curved lamellae in mid‐ and caudal pons. Dorsal trunk projections are in medial and ventral locations. Ventral trunk/hip projections encircle the peduncle in the caudal pons. Foot projections are heaviest caudally in laterally placed, curved lamellae. These results have relevance for anatomical clinical correlations in the human basis pontis. Furthermore, the dichotomy of motor‐predominant caudal pons projections to cerebellar anterior lobe, contrasted with associative‐predominant rostral pons projections to cerebellar posterior lobe, is consistent with new hypotheses regarding the cerebellar contribution to motor activity and cognitive processing. J. Comp. Neurol. 478:248–268, 2004. © 2004 Wiley‐Liss, Inc.

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  • The NRTP receives inputs mainly from the sensorimotor areas, the prefrontal areas and the parietal association areas.

    “The NRTP receives inputs mainly from the sensorimotor areas, the prefrontal areas and the parietal association areas (Schmahmann et al., 2004).”

    From The Cerebro-Cerebellum as a Locus of Forward Model: A Review (2020) · cites this paper as Schmahmann et al., 2004

Cites

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1 of the 82 references couldn’t be matched to a known paper.

Research works printed but not linked: 8

  1. Bechterew W, 1885, Zur Anatomie der Schenkel des Kleinhirns, insbesondere der Brückenarme, Neurol Centralblatt, 4, 121
  2. Borowiecki S, 1911, Vergleichen‐anatomische und experimentelle Untersuchungen uber des Brückengrau und die wichtigsten Verbindungen der Brücke, Arb Hirnanat Inst Zurich, 5, 39
  3. Dejerine J, 1893, Sur l'origine corticale et le trajet intra‐cérébral des fibers de l'étage inférieur ou pied du pédoncule cérébral, Mem Soc Biol, 9, 193
  4. Masuda H, 1914, Über das Brückengrau des Menschen (Griseum Pontis) und dessen nähere Beziehungen zum Kleinhirn und Grosshirn, Arb Hirnanat Inst Zurich, 9, 1
  5. Nyby O, 1951, An experimental investigation of the corticopontine projection in Macaca mulatta. Oslo: Skrifter utgitt av det Norske Vedenskapsakademie: 1, Mat Nat Klasse, 3, 1
  6. Schmahmann JD, 1995, The organization of the motor corticopontine projection in monkey, Soc Neurosci Abstr, 21, 410
  7. Snider RS, 1952, Interrelations of cerebellum and brainstem, Res Publ Assoc Nerv Ment Dis, 30, 267
  8. Spitzer A, 1907, Über experimentelle Läsionen an der Gehirnbasis, Arb Neurol Inst, 16, 348

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Authors
Schmahmann, J. D., Rosene, D. L., & Pandya, D. N.
Affiliations
  • Harvard University (US)
  • Boston University (US)
Corresponding author
Schmahmann, Jeremy D.
ORCID
Venue
Journal of Comparative Neurology
Publisher
Wiley
Published
2004-09-14
Volume
478
Issue
3
Pages
248-268
ISSN
  • 0021-9967 (ISSN-L)
  • 1096-9861
DOI
10.1002/cne.20286
OpenAlex
W2033582272
Semantic Scholar
7a3e12d1c90277ccbc98ea619b81882bb4a1c31e
Cited by
146
References
82
Citations by year
2026: 4 · 2025: 2 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 10 · 2020: 7 · 2019: 7 · 2018: 7 · 2017: 3 · 2016: 6 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 10
FWCI
7.94
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • The Journal of Comparative Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
primary motor cortex, supplementary motor area, topographic organization, corticospinal fibers, cerebellar anterior lobe, rhesus monkeys, internal capsule, cerebral peduncle, isotope tracers
MeSH terms
Animals, Autoradiography, Brain Mapping, Cerebral Cortex, Face, Foot, Hand, Functional Laterality, Macaca mulatta, Motor Neurons, Neural Pathways, Pons, Radioisotopes

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