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Altered Emotional Interference Processing in Affective and Cognitive-Control Brain Circuitry in Major Depression
Open accessAbstract
Background Major depression is characterized by a negativity bias: an enhanced responsiveness to, and memory for, affectively negative stimuli. However, it is not yet clear whether this bias represents 1) impaired top-down cognitive control over affective responses, potentially linked to deficits in dorsolateral prefrontal cortex function; or 2) enhanced bottom-up responses to affectively laden stimuli that dysregulate cognitive control mechanisms, potentially linked to deficits in amygdala and anterior cingulate function.Methods We used an attentional interference task using emotional distracters to test for top-down versus bottom-up dysfunction in the interaction of cognitive-control circuitry and emotion-processing circuitry. A total of 27 patients with major depression and 24 control participants was tested. Event-related functional magnetic resonance imaging was carried out as participants directly attended to, or attempted to ignore, fear-related stimuli.Results Compared with control subjects, patients with depression showed an enhanced amygdala response to unattended fear-related stimuli (relative to unattended neutral). By contrast, control participants showed increased activity in right dorsolateral prefrontal cortex (Brodmann areas 46/9) when ignoring fear stimuli (relative to neutral), which the patients with depression did not show. In addition, the depressed participants failed to show evidence of error-related cognitive adjustments (increased activity in bilateral dorsolateral prefrontal cortex on posterror trials), but the control group did show them.Conclusions These results suggest multiple sources of dysregulation in emotional and cognitive control circuitry in depression, implicating both top-down and bottom-up dysfunction.
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“cognitive domains that are all impacted in depression [93–96]”
From Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study (2026) · cites this paper as [95]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“MDD was associated with reduced recruitment of the dlPFC [160, 161, 170, 244-246] and dACC [160,161,246] in contexts requiring task-irrelevant negative cues to be ignored or behavioral adjustments after errors.”
From Prefrontal cortex and depression (2022) · cites this paper as [161]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This deficit in inhibitory regulation by the anterior cingulate and prefrontal results in an overactive amygdala as well as biases in memory towards negative stimuli and away from positive stimuli [57–60].”
From Association between time perspective and metacognition among Lebanese adults: the mediating role of mindfulness (2023) · cites this paper as [59]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Relative to healthy controls, individuals with MDD showed reduced dlPFC activation during tasks involving matching negative facial expressions [159], presenting negative stimuli [156, 160], requiring to ignore negative faces [161], or inducing emotional interference [162].”
From Prefrontal cortex and depression (2022) · cites this paper as [161]
In the citing paper
“the right DLPFC has been shown to be less active in individuals with depression than in healthy controls during observation of threat-related facial expressions (Mingtian et al., 2012) and of fearful faces, even if these were not explicitly attended to (Fales et al., 2008).”
From Social functioning in major depressive disorder (2016) · cites this paper as Fales et al., 2008
In the citing paper
“Actively depressed patients also show increased neural responses to positive and negative facial expressions in the subgenual portion of the anterior cingulate cortex, a region involved in the physiologic response of emotional processing.45,46,52,63”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“These findings may be interpreted as deficits in the cognitive control of emotion during the processing of emotionally salient stimuli (faces).”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“Elevated activity and altered connectivity of the amgydala and ventromedial regions, such as the subgenual cingulate, may result in the negative processing bias inherent in the disorder.”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“Conversely, when patients with MDD were asked to ignore negative stimuli, they failed to recruit the DLPFC which was correlated with amygdala hyperactivity48.”
From Dysregulation of adult hippocampal neuroplasticity in major depression: Pathogenesis and therapeutic implications (2022) · cites this paper as [48]
In the citing paper
“Hypoactivation of these regions is observed in MDD patients when performing tasks that require ignoring negative valence distracters [183].”
From Plasticity of synapses and reward circuit function in the genesis and treatment of depression (2023) · cites this paper as [183]
In the citing paper
“DlPFC in particular has been previously linked with neural changes in depression, typically demonstrating hypoactivation (Fales et al., 2008; Siegle et al., 2007)”
From Neural correlates of emotional processing in depression: Changes with cognitive behavioral therapy and predictors of treatment response (2011) · cites this paper as Fales et al., 2008
In the citing paper
“Past studies have found impairments in cognitive control in individuals with depression when confronted with emotional information (Beevers et al. 2010; Ditcher et al. 2009; Fales et al. 2008).”
From Executive Function Deficits in Daily Life Prospectively Predict Increases in Depressive Symptoms (2014) · cites this paper as Fales et al. 2008
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Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Conflict monitoring and cognitive control
Botvinick, M. M., Braver, T. S., Barch, D. M., Carter, C. S., & Cohen, J. D. (2001) · Psychological Review · doi:10.1037/0033-295x.108.3.624 · Cited by 7,351
Self-citationThe cognitive control of emotion
OCHSNER, K., & GROSS, J. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.03.010 · Cited by 4,495
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Movement‐Related effects in fMRI time‐series
Friston, K. J., Williams, S., Howard, R., Frackowiak, R. S. J., & Turner, R. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910350312 · Cited by 3,774
Conflict monitoring and anterior cingulate cortex: an update
Botvinick, M. M., Cohen, J. D., & Carter, C. S. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.10.003 · Cited by 3,623
Self-citationDeciding advantageously before knowing the advantageous strategy
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997) · Science · doi:10.1126/science.275.5304.1293 · Cited by 3,547
Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance
Carter, C. S., Braver, T. S., Barch, D. M., Botvinick, M. M., Noll, D., & Cohen, J. D. (1998) · Science · doi:10.1126/science.280.5364.747 · Cited by 3,273
Self-citation
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Items 301–400 of 517
Li, G., & Yap, P. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.940842 · Cited by 17
The neuroanatomy of social trust predicts depression vulnerability
Fermin, A. S. R., Kiyonari, T., Matsumoto, Y., Takagishi, H., Li, Y., Kanai, R., Sakagami, M., Akaishi, R., Ichikawa, N., Takamura, M., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-20443-w · Cited by 21
Intracranial directed connectivity links subregions of the prefrontal cortex to major depression
Myers, J. C., Xiao, J., Mathura, R. K., Shofty, B., Gates, V., Adkinson, J., Allawala, A. B., Anand, A., Gadot, R., Najera, R. A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61487-6 · Cited by 18
“The study found specific connectivity patterns between the ACC, dlPFC and OFC correlated with depression severity and that these changes were different across the two hemispheres.”
Cross-lagged analysis of rumination and social anxiety among Chinese college students
Wu, P., Cao, K., Feng, W., & Lv, S. (2024) · BMC Psychology · doi:10.1186/s40359-023-01515-6 · Cited by 18
Passa, A.-M. D., Prokop-Millar, S., Yaya, H., Dabir, M., McIntyre‐Wood, C., Fein, A. J., MacKillop, E., MacKillop, J. M., & Duarte, D. G. G. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.05.011 · Cited by 20
Improved emotional conflict control triggered by the processing priority of negative emotion
Yang, Q., Wang, X., Yin, S., Zhao, X., Tan, J., & Chen, A. (2016) · Scientific Reports · doi:10.1038/srep24302 · Cited by 17
Neural Correlates of Trait Rumination During an Emotion Interference Task in Women With PTSD
Buchholz, K. R., Bruce, S. E., Koucky, E. M., Artime, T. M., Wojtalik, J. A., Brown, W. J., & Sheline, Y. I. (2016) · Journal of Traumatic Stress · doi:10.1002/jts.22112 · Cited by 17
Self-citationBalzarotti, S., & Colombo, B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159555 · Cited by 17
Transdiagnostic neural markers of emotion–cognition interaction in psychotic disorders.
Sabharwal, A., Szekely, A., Kotov, R., Mukherjee, P., Leung, H., Barch, D. M., & Mohanty, A. (2016) · Journal of Abnormal Psychology · doi:10.1037/abn0000196 · Cited by 19
Self-citationKwak, Y. T., Yang, Y., & Koo, M. (2016) · Dementia and Neurocognitive Disorders · doi:10.12779/dnd.2016.15.4.103 · Cited by 20
Pérez-Valenzuela, C., Terreros, G., & Dagnino‐Subiabre, A. (2018) · Reviews in the Neurosciences · doi:10.1515/revneuro-2018-0018 · Cited by 18
Seok, D., Smyk, N. J., Jaskir, M., Cook, P. A., Elliott, M. A., Girelli, T., Scott, J. C., Balderston, N. L., Beer, J. C., Stock, J., et al. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102489 · Cited by 16
Self-citationBartczak, M., & Bokus, B. (2014) · Journal of Psycholinguistic Research · doi:10.1007/s10936-014-9286-6 · Cited by 16
Meter, A. V., & Youngstrom, E. A. (2015) · Cognitive Therapy and Research · doi:10.1007/s10608-015-9738-9 · Cited by 18
Beyond “Cold” Cognition: Exploring Cognitive Control of Emotion as a Risk Factor for Psychosis
Tully, L. M., & Niendam, T. A. (2014) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-014-0016-z · Cited by 17
Neuroticism and Its Associated Brain Activation in Women With PTSD
Brown, N. B., Wojtalik, J. A., Turkel, M., Vuper, T. C., Strasshofer, D. R., Sheline, Y. I., & Bruce, S. E. (2016) · Journal of Interpersonal Violence · doi:10.1177/0886260516682519 · Cited by 15
Self-citationLi, S., Chen, J., Gao, K., Xu, F., & Zhang, D. (2023) · Psychological Medicine · doi:10.1017/s0033291723000028 · Cited by 18
Kang, W., Kang, Y., Kim, A., Kim, H., Han, K., & Ham, B. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.145 · Cited by 17
Robert, G., Bannier, É., Comte, M., Domain, L., Corouge, I., Dondaine, T., Batail, J.-M. V., Ferré, J., Fakra, É., & Drapier, D. (2021) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.200074 · Cited by 14
Effects of chronic stress on the auditory system and fear learning: an evolutionary approach
Dagnino‐Subiabre, A. (2013) · Reviews in the Neurosciences · doi:10.1515/revneuro-2012-0079 · Cited by 15
Januszko, P., Gmaj, B., Piotrowski, T., Kopera, M., Klimkiewicz, A., Wnorowska, A., Wołyńczyk-Gmaj, D., Brower, K. J., Wojnar, M., & Jakubczyk, A. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108393 · Cited by 15
Postpartum depression: A role for psychedelics?
Jairaj, C., & Rucker, J. (2022) · Journal of Psychopharmacology · doi:10.1177/02698811221093793 · Cited by 16
Anxiety Comorbidities: Mood Disorders, Substance Use Disorders, and Chronic Medical Illness
Rogers, A. H., Wieman, S. T., & Baker, A. W. (2019) · Current clinical psychiatry · doi:10.1007/978-3-030-30687-8_5 · Cited by 16
Atrophic Corpus Callosum Associated with Altered Functional Asymmetry in Major Depressive Disorder
Ran, S., Zuo, Z., Li, C., Yin, X., Qu, W., Tang, Q., Wang, Y., Shi, Y., & Li, H. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s245078 · Cited by 14
Behavioral and neural mechanisms underlying cognitive vulnerability models of depression.
Auerbach, R. P., Webb, C. A., Gardiner, C. K., & Pechtel, P. (2013) · Journal of Psychotherapy Integration · doi:10.1037/a0031417 · Cited by 14
Prouty, E. W., Chandler, D. J., Gao, W., & Waterhouse, B. D. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14355 · Cited by 13
Theta oscillatory dynamics serving cognitive control index psychosocial distress in youth
Schantell, M. D., Taylor, B. K., Mansouri, A., Arif, Y., Coutant, A. T., Rice, D. L., Wang, Y., Calhoun, V. D., Stephen, J. M., & Wilson, T. W. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100599 · Cited by 14
Optogenetics: What it has uncovered in potential pathways of depression
Cheng, Z., Cui, R., Ge, T., Yang, W., & Li, B. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104596 · Cited by 14
Jamieson, A. J., Harrison, B. J., & Davey, C. G. (2021) · Psychological Medicine · doi:10.1017/s0033291721002567 · Cited by 13
Luo, L., Langley, C., Moreno-López, L., Kendrick, K. M., Menon, D. K., Stamatakis, E. A., & Sahakian, B. J. (2021) · Psychological Medicine · doi:10.1017/s0033291721004724 · Cited by 12
Interpersonal Violence, Depression, and Executive Function
Hebenstreit, C. L., DePrince, A. P., & Chu, A. T. (2014) · Journal of Aggression Maltreatment & Trauma · doi:10.1080/10926771.2014.872749 · Cited by 15
Wang, Z., Zou, Z., Xiao, J. F., Wang, P., Luo, Y., Min, W., He, Y., Yuan, C., Su, Y., Yang, C., et al. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104929 · Cited by 12
The neurobiology of emotion-cognition interactions
Shackman, A. J., Pessoa, L., Hendler, T., & Okon‐Singer, H. (2015) · Frontiers research topics · doi:10.3389/978-2-88919-528-2 · Cited by 13
Failure in Cognitive Suppression of Negative Affect in Adolescents with Generalized Anxiety Disorder
Yin, D., Liu, W., Zeljic, K., Lv, Q., Wang, Z., You, M., Men, W., Fan, M., Cheng, W., & Wang, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-07063-5 · Cited by 13
Späti, J., Chumbley, J., Doerig, N., Brakowski, J., Grosse Holtforth, M., Seifritz, E., & Spinelli, S. (2015) · Journal of Psychiatry & Neuroscience · doi:10.1503/jpn.140225 · Cited by 11
Li, E., Xiao, F., Zou, T., & Guo, J. (2021) · Brain and Language · doi:10.1016/j.bandl.2021.104994 · Cited by 11
Li, K., Yang, J., Becker, B., & Li, X. (2023) · Neurophotonics · doi:10.1117/1.nph.10.2.025011 · Cited by 10
Han, W., Su, Y., Wang, X., Yang, T., Zhao, G., Mao, R., Zhu, N., Zhou, R., Wang, X., Wang, Y., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.03.057 · Cited by 11
Hou, Q., Wang, C., Hou, C., Tan, J., He, S., Tang, L., Yong, N., Ding, X., Jiang, G., Liu, J., et al. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00332-4 · Cited by 11
Lass, A. N. S., Rokke, P. D., & Winer, E. S. (2021) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2021.100127 · Cited by 9
Spies, M., Murgaš, M., Vraka, C., Philippe, C., Gryglewski, G., Nics, L., Balber, T., Baldinger, P., Hartmann, A. M., Rujescu, D., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02506-2 · Cited by 13
Changes in interoceptive accuracy related to emotional interference in somatic symptom disorder
Lee, D., Kim, S. J., Cheon, J., Jung, Y., & Kang, J. I. (2024) · BMC Psychology · doi:10.1186/s40359-024-01778-7 · Cited by 16
Hsu, L., Lane, T. J., Wu, C. W., Lin, C.-Y. E., Yeh, C.-B., Kao, H., & Lin, C. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00364-w · Cited by 10
DLPFC controls the rapid neural response to visual threat: An ERP and rTMS study
Cinq-Mars, J., Blumenthal, A., Grund, A., Hétu, S., & Blanchette, I. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147850 · Cited by 11
Systems Neuroscience in Late-Life Depression
Manning, K. J., & Steffens, D. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802456-0.00011-x · Cited by 11
Functional Neuroimaging of Deficits in Cognitive Control
Mackie, M., & Fan, J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803676-1.00011-8 · Cited by 12
On the relationship between negative affective priming and prefrontal cognitive control mechanisms
Falquez, R., Lang, S., Dinu-Biringer, R., Nees, F., Arens, E. A., Kotchoubey, B., Berger, M. C., & Barnow, S. (2015) · Cognition & Emotion · doi:10.1080/02699931.2014.994476 · Cited by 10
Semantic Distances in Depression: Relations Between ME and PAST, FUTURE, JOY, SADNESS, HAPPINESS
Bartczak, M., & Bokus, B. (2016) · Journal of Psycholinguistic Research · doi:10.1007/s10936-016-9442-2 · Cited by 11
Cha, J., Raj, D., Choi, K. S., Rajendra, J. K., Nemeroff, C. B., Felger, J. C., Craighead, W. E., Mayberg, H. S., & Dunlop, B. W. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.06.026 · Cited by 12
Situationally appropriate behavior: translating situations into appetitive behavior modes
Behrendt, R. (2013) · Reviews in the Neurosciences · doi:10.1515/revneuro-2013-0037 · Cited by 9
“, 2005) or to fear-related stimuli (attended or unattended) (Fales et al., 2008).”
Neural Foundations of Major Depression
Hamilton, J. P., Furman, D. J., & Gotlib, I. H. (2011) · Frontiers in neuroscience · doi:10.1201/b11232-4 · Cited by 9
Bases Neurais da Ansiedade Matemática: implicações para o processo de ensino-aprendizagem
Moura-Silva, M. G., Bento‐Torres, J., & Gonçalves, T. O. (2020) · Bolema Boletim de Educação Matemática · doi:10.1590/1980-4415v34n66a12 · Cited by 17
Max, S. M., Schroeder, P. A., Jens Blechert, A., Giel, K. E., Ehlis, A., & Plewnia, C. (2021) · Brain Structure and Function · doi:10.1007/s00429-021-02232-9 · Cited by 9
Differences in the neural correlates of affective responses in depressed and healthy women
Gollan, J. K., Buchanan, A., Connolly, M. E., Hoxha, D., Sankin, L. S., Csernansky, J. G., & Wang, X. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.10.006 · Cited by 9
“…documented a decrease of amygdala activation in depressed relative to healthy participants (Siegle et al., 2007; Hamilton et al., 2008), while other studies have shown no group differences (Davidson, 2002; Irwin et al., 2004; Beauregard et al., 2006; Johnstone et al., 2007; Fales et al., 2008).”
Affect and neural activity in women with PTSD during a task of emotional interference
Brown, W. J., Wojtalik, J. A., Dewey, D., Bruce, S. E., Yang, Z., & Sheline, Y. I. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.065 · Cited by 9
Self-citationCharacterization of specific spatial functional connectivity difference in depression during sleep
Lian, J., Song, Y., Zhang, Y., Guo, X., Wen, J., & Luo, Y. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24947 · Cited by 9
Segrave, R. A., Thomson, R. H., Cooper, N. R., Croft, R. J., Sheppard, D. M., & Fitzgerald, P. B. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.03.004 · Cited by 10
Ren, P., Chapman, B. P., Zhang, Z., Schifitto, G., & Lin, F. V. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.07.021 · Cited by 9
“Previous studies have reported that the amygdala can modulate the efficiency of the executive control network (Fales et al., 2008; Herwig et al., 2007; Krug and Carter, 2010).”
Stolicyn, A., Harris, M. A., de Nooij, L., Shen, X., Macfarlane, J. A., Campbell, A., McNeil, C. J., Sandu, A., Murray, A. D., Waiter, G. D., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.038 · Cited by 9
Schräder, J., Herzberg, L., Jo, H., Hernandez‐Pena, L., Koch, J., Habel, U., & Wagels, L. (2024) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.07.005 · Cited by 9
Li, Y., Qing‐Xiu, L., Wang, J., Xiang, H., Zhang, R., & Huang, C.-Q. (2021) · International Journal of Neuroscience · doi:10.1080/00207454.2021.1928114 · Cited by 8
Irrelevant Threats Linger and Affect Behavior in High Anxiety
Aberg, K. C., Toren, I., & Paz, R. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1186-22.2022 · Cited by 8
Taeye, L. D., Pourtois, G., Meurs, A., Boon, P., Vonck, K. E. J., Carrette, E., & Raedt, R. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116817 · Cited by 8
Godara, M., Sánchez-López, Á., & Raedt, R. D. (2023) · Behaviour Research and Therapy · doi:10.1016/j.brat.2023.104354 · Cited by 8
Cui, J., Li, M., Wu, Y., Shen, Q., Yan, W., Zhang, S., Chen, M., & Zhou, J. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.08.024 · Cited by 7
Abnormal resting-state functional connectivity in adolescent depressive episodes
Liang, N., Xue, Z., Xu, J., Sun, Y., Li, H., & Lu, J. (2025) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2025.111961 · Cited by 7
Neuroticism modulates functional connectivity of the midcingulate cortex during emotional conflict
Kim, H., Park, J., Kuhn, M., Kim, M. J., & Hur, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-97529-8 · Cited by 7
Emotion regulation ability compensates for the depression-related negativity bias
Düsing, R., Radtke, E. L., Kühl, J., Konrad, C., Vandekerckhove, M. M. P., & Quirin, M. (2021) · Acta Psychologica · doi:10.1016/j.actpsy.2021.103414 · Cited by 7
Wei, J., Li, L., Zhang, J., Shi, E., Yang, J., & Liu, X. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01246-7 · Cited by 8
Guo, X., Zhou, Q., Lu, Y., Xu, Z., Wen, Z., Gu, P., Tian, S., & Wang, Y. (2024) · Brain and Behavior · doi:10.1002/brb3.3638 · Cited by 7
“…2022; Yang et al., 2020). network (Hutchinson et al., 2009; Vossel et al., 2014), and its weakened activity may lead to patients with major depressive disorder paying selective attention to negative stimuli while inhibiting the processing of other stimuli (Fales et al., 2008; Olivo et al., 2018).”
Hubbard, N. A., Auerbach, R. P., Siless, V., Lo, N., Frosch, I. R., Clark, D. E., Jones, R. J., Kremens, R., Pinaire, M., Souza, F. V. D., et al. (2022) · Clinical Psychological Science · doi:10.1177/21677026221079628 · Cited by 7
Metastability and Transients in Brain Dynamics: Problems and Rigorous Results
Afraimovich, V., Muezzinoglu, M. K., & Rabinovich, M. I. (2010) · Nonlinear physical science · doi:10.1007/978-3-642-12343-6_4 · Cited by 7
Lu, Y., Song, L., Huang, C., Fan, T., Huang, J., Zhang, L., Luo, X., Li, Y., & Shen, Y. (2024) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2024.111914 · Cited by 6
Altered effective connectivity among face-processing systems in major depressive disorder
Sheng, F., Wang, Y., Li, R., Li, X., Chen, X., Zhang, Z., Liu, R., Zhang, L., Zhou, Y., & Wang, G. (2024) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.230123 · Cited by 5
Proactive engagement of cognitive control modulates implicit approach-avoidance bias
Harlé, K. M., Bomyea, J. A., Spadoni, A. D., Simmons, A. N., & Taylor, C. T. (2020) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-020-00815-3 · Cited by 6
A Neural Predictive Model of Negative Emotions for COVID-19
Mao, Y., Wei, D., Yang, W., Chen, Q., Sun, J., Yu, Y., Yu, L., Zhuang, K., Wang, X., He, L., et al. (2022) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2022.3181671 · Cited by 7
Soncin, L., Belquaid, S., McGonigal, A., Giusiano, B., Bartoloméi, F., & Faure, S. (2023) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2023.109396 · Cited by 6
Reconocimiento de Emociones Faciales en Adultos Mayores de la Ciudad de Córdoba
Narambuena, L., Vaiman, M., & Pereno, G. L. (2016) · Psykhe (Santiago) · doi:10.7764/psykhe.25.1.791 · Cited by 6
Wong, S. F., Trespalacios, F., & Ellenbogen, M. A. (2020) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2020.02.005 · Cited by 6
Zhang, Q., Li, X., Yan, H., Wang, Y., Ou, Y., Yu, Y., Liang, J., Liao, H., Wu, W., Mai, X., et al. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1056868 · Cited by 5
Godara, M., & Singer, T. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13113295 · Cited by 5
Feng, T., Gaebler, A. J., Keller, M., Zweerings, J., Li, H., Cong, F., & Mathiak, K. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03386-4 · Cited by 5
“…previous studies identi fi ed hypo-activation of the dorsolateral prefrontal cortex (DLPFC) [45], de fi cits in down-regulating amygdala responses during presentation of negative stimuli leading to a failure to regulate negative mood [46, 47] and expansion of the frontostriatal salience network [48].”
Montes, L. G. A., Alcántara, H. P., Cedeño, B. A. P., García, A. O. H., & Rojas, P. E. F. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.03.010 · Cited by 6
Huang, B.-K., Zhou, J.-H., Deng, Y., Li, C., Ning, B., Ye, Z.-Y., Huang, X., Zhao, M.-M., Dong, D., Liu, M., et al. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148947 · Cited by 5
Kumar, P., Harmer, C. J., & Dourish, C. T. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-386945-6.00012-3 · Cited by 6
Homan, P., Drevets, W. C., & Hasler, G. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000339 · Cited by 5
Sommer, A., Fallgatter, A. J., & Plewnia, C. (2021) · Journal of Neural Transmission · doi:10.1007/s00702-021-02444-7 · Cited by 5
Decoding Human Cognitive Control Using Functional Connectivity of Local Field Potentials
Avvaru, S., Provenza, N. R., Widge, A. S., & Parhi, K. K. (2021) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc46164.2021.9630706 · Cited by 5
Attentional bias for rejection and sad words in Chinese left‐behind children with depression
Peng, J., Li, J., Zhang, Y., Liang, L., Ye, G., & Xiao, W. (2023) · Child Care Health and Development · doi:10.1111/cch.13166 · Cited by 5
Chahine, A., El Zouki, C.-J., Mhanna, M., Hallit, S., & Obeid, S. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05356-w · Cited by 4
A free association semantic task for fNIRS-based perinatal depression assessment
Chen, D., Yang, X., Liang, Y., Huang, C., Zhang, S., Li, Y., Li, Y., Li, X., Mu, W., Zhang, D., et al. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2024.1491923 · Cited by 4
Hong, C., Cody, D., Zhu, Y., Chen, S., Zhang, Y., Yuan, H., & Yang, D. (2022) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2022-0054 · Cited by 5
He, Z., Zheng, Y., Ni, J., Huang, J., Pang, Q., Chen, T., Muhlert, N., & Elliott, R. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad399 · Cited by 4
Liu, X., Chen, B., Zhang, H., Cui, Y., Wang, B., Wang, Y., Zhao, T., Yan, Y., Sha, S., Ren, Y., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119599 · Cited by 4
Cognitive Biomarkers in Depression
Robinson, O. J., & Sahakian, B. J. (2013) · Oxford University Press eBooks · doi:10.1093/med/9780199796816.003.0035 · Cited by 4
Asselmann, E., Hilbert, K., Hoyer, J., Wïttchen, H., Lieb, R., Bühringer, G., & Beesdo‐Baum, K. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.11.046 · Cited by 4
An Overview of Machine Learning Applications in Mood Disorders
Topolski, N., Jeong, S. H., & Mwangi, B. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108623018.017 · Cited by 4
Depression with comorbid borderline personality disorder - could ketamine be a treatment catalyst?
Więdłocha, M., Marcinowicz, P., Komarnicki, J., Tobiaszewska, M., Dębowska, W., Dębowska, M. D., & Szulc, A. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1398859 · Cited by 8
Li, Q., Cao, D., Li, Y., & Tang, Y. (2017) · PubMed Central · doi:10.7507/1001-5515.201606048 · Cited by 4
Alterations of novelty processing in major depressive disorder
Francis, A. M., Bissonnette, J. N., Hull, K. M., Leckey, J., Pimer, L., Berrigan, L. I., & Fisher, D. J. (2021) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2021.100083 · Cited by 4
Metadata
- Authors
- Fales, C. L., Barch, D. M., Rundle, M. M., Mintun, M. A., Snyder, A. Z., Cohen, J. D., Mathews, J., & Sheline, Y. I.
- Affiliations
- Washington University in St. Louis (US)
- Princeton University (US)
- Corresponding author
- Sheline, Yvette I.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-02
- Volume
- 63
- Issue
- 4
- Pages
- 377-384
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC2268639
- OpenAlex
- W2161710337
- Cited by
- 517
- References
- 55
- Citations by year
- 2026: 9 · 2025: 21 · 2024: 32 · 2023: 20 · 2022: 21 · 2021: 57 · 2020: 27 · 2019: 22 · 2018: 15 · 2017: 30 · 2016: 35 · 2015: 35 · 2014: 34 · 2013: 27 · 2012: 38
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH066031, R01 MH06603101, R01 MH64821, R01MH064821)
- National Center for Research Resources (K24 RR18192, K24RR018192)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- major depressive disorder, negativity bias, emotional interference, attentional interference, top-down cognitive control, amygdala, dorsolateral prefrontal cortex, anterior cingulate cortex, emotional distracters, event-related fMRI
- MeSH terms
- Adult, Affect, Amygdala, Attention, Cognition, Cognition Disorders, Depressive Disorder, Major, Major Depressive Disorder, Face, Fear, Female, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Nerve Net, Neuropsychological Tests, Surveys and Questionnaires, Visual Perception
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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