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Altered Emotional Interference Processing in Affective and Cognitive-Control Brain Circuitry in Major Depression
Open accessAbstract
Background Major depression is characterized by a negativity bias: an enhanced responsiveness to, and memory for, affectively negative stimuli. However, it is not yet clear whether this bias represents 1) impaired top-down cognitive control over affective responses, potentially linked to deficits in dorsolateral prefrontal cortex function; or 2) enhanced bottom-up responses to affectively laden stimuli that dysregulate cognitive control mechanisms, potentially linked to deficits in amygdala and anterior cingulate function.Methods We used an attentional interference task using emotional distracters to test for top-down versus bottom-up dysfunction in the interaction of cognitive-control circuitry and emotion-processing circuitry. A total of 27 patients with major depression and 24 control participants was tested. Event-related functional magnetic resonance imaging was carried out as participants directly attended to, or attempted to ignore, fear-related stimuli.Results Compared with control subjects, patients with depression showed an enhanced amygdala response to unattended fear-related stimuli (relative to unattended neutral). By contrast, control participants showed increased activity in right dorsolateral prefrontal cortex (Brodmann areas 46/9) when ignoring fear stimuli (relative to neutral), which the patients with depression did not show. In addition, the depressed participants failed to show evidence of error-related cognitive adjustments (increased activity in bilateral dorsolateral prefrontal cortex on posterror trials), but the control group did show them.Conclusions These results suggest multiple sources of dysregulation in emotional and cognitive control circuitry in depression, implicating both top-down and bottom-up dysfunction.
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“cognitive domains that are all impacted in depression [93–96]”
From Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study (2026) · cites this paper as [95]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“MDD was associated with reduced recruitment of the dlPFC [160, 161, 170, 244-246] and dACC [160,161,246] in contexts requiring task-irrelevant negative cues to be ignored or behavioral adjustments after errors.”
From Prefrontal cortex and depression (2022) · cites this paper as [161]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This deficit in inhibitory regulation by the anterior cingulate and prefrontal results in an overactive amygdala as well as biases in memory towards negative stimuli and away from positive stimuli [57–60].”
From Association between time perspective and metacognition among Lebanese adults: the mediating role of mindfulness (2023) · cites this paper as [59]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Relative to healthy controls, individuals with MDD showed reduced dlPFC activation during tasks involving matching negative facial expressions [159], presenting negative stimuli [156, 160], requiring to ignore negative faces [161], or inducing emotional interference [162].”
From Prefrontal cortex and depression (2022) · cites this paper as [161]
In the citing paper
“the right DLPFC has been shown to be less active in individuals with depression than in healthy controls during observation of threat-related facial expressions (Mingtian et al., 2012) and of fearful faces, even if these were not explicitly attended to (Fales et al., 2008).”
From Social functioning in major depressive disorder (2016) · cites this paper as Fales et al., 2008
In the citing paper
“Actively depressed patients also show increased neural responses to positive and negative facial expressions in the subgenual portion of the anterior cingulate cortex, a region involved in the physiologic response of emotional processing.45,46,52,63”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“These findings may be interpreted as deficits in the cognitive control of emotion during the processing of emotionally salient stimuli (faces).”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“Elevated activity and altered connectivity of the amgydala and ventromedial regions, such as the subgenual cingulate, may result in the negative processing bias inherent in the disorder.”
From Systematic review of the neural basis of social cognition in patients with mood disorders (2012) · cites this paper as [52]
In the citing paper
“Conversely, when patients with MDD were asked to ignore negative stimuli, they failed to recruit the DLPFC which was correlated with amygdala hyperactivity48.”
From Dysregulation of adult hippocampal neuroplasticity in major depression: Pathogenesis and therapeutic implications (2022) · cites this paper as [48]
In the citing paper
“Hypoactivation of these regions is observed in MDD patients when performing tasks that require ignoring negative valence distracters [183].”
From Plasticity of synapses and reward circuit function in the genesis and treatment of depression (2023) · cites this paper as [183]
In the citing paper
“DlPFC in particular has been previously linked with neural changes in depression, typically demonstrating hypoactivation (Fales et al., 2008; Siegle et al., 2007)”
From Neural correlates of emotional processing in depression: Changes with cognitive behavioral therapy and predictors of treatment response (2011) · cites this paper as Fales et al., 2008
In the citing paper
“Past studies have found impairments in cognitive control in individuals with depression when confronted with emotional information (Beevers et al. 2010; Ditcher et al. 2009; Fales et al. 2008).”
From Executive Function Deficits in Daily Life Prospectively Predict Increases in Depressive Symptoms (2014) · cites this paper as Fales et al. 2008
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Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Conflict monitoring and cognitive control
Botvinick, M. M., Braver, T. S., Barch, D. M., Carter, C. S., & Cohen, J. D. (2001) · Psychological Review · doi:10.1037/0033-295x.108.3.624 · Cited by 7,351
Self-citationThe cognitive control of emotion
OCHSNER, K., & GROSS, J. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.03.010 · Cited by 4,495
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Movement‐Related effects in fMRI time‐series
Friston, K. J., Williams, S., Howard, R., Frackowiak, R. S. J., & Turner, R. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910350312 · Cited by 3,774
Conflict monitoring and anterior cingulate cortex: an update
Botvinick, M. M., Cohen, J. D., & Carter, C. S. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.10.003 · Cited by 3,623
Self-citationDeciding advantageously before knowing the advantageous strategy
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997) · Science · doi:10.1126/science.275.5304.1293 · Cited by 3,547
Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance
Carter, C. S., Braver, T. S., Barch, D. M., Botvinick, M. M., Noll, D., & Cohen, J. D. (1998) · Science · doi:10.1126/science.280.5364.747 · Cited by 3,273
Self-citation
Cited by
Sorted by citations
Kaiser, R. H., Andrews-Hanna, J. R., Wager, T. D., & Pizzagalli, D. A. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0071 · Cited by 2,281
Neural mechanisms of the cognitive model of depression.
Disner, S. G., Beevers, C. G., Haigh, E. A. P., & Beck, A. T. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3027 · Cited by 1,718
The default mode network and self-referential processes in depression
Sheline, Y. I., Barch, D. M., Price, J. L., Rundle, M. M., Vaishnavi, S. N., Snyder, A. Z., Mintun, M. A., Wang, S., Coalson, R. S., & Raichle, M. E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812686106 · Cited by 1,480
Self-citationSheline, Y. I., Price, J. L., Yan, Z., & Mintun, M. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000446107 · Cited by 1,196
Self-citationStress, sensitive periods and maturational events in adolescent depression
Andersen, S. L., & Teicher, M. H. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.01.004 · Cited by 1,005
Frontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response
Pizzagalli, D. A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.166 · Cited by 945
Major depressive disorder: new clinical, neurobiological, and treatment perspectives
Kupfer, D. J., Frank, E., & Phillips, M. L. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60602-8 · Cited by 894
Stress-induced obesity and the emotional nervous system
Dallman, M. F. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.10.004 · Cited by 814
Social functioning in major depressive disorder
Kupferberg, A., Bicks, L., & Hasler, G. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.002 · Cited by 663
“Specifically, the right DLPFC has been shown to be less active in individuals with depression than in healthy controls during observation of threat-related facial expressions (Mingtian et al., 2012) and of fearful faces, even if these were not explicitly attended to (Fales et al., 2008).”
Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex
Covington, H. E., Lobo, M. K., Maze, I., Vialou, V., Hyman, J. M., Zaman, S., LaPlant, Q., Mouzon, E., Ghose, S., Tamminga, C. A., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1731-10.2010 · Cited by 621
Prefrontal cortex and depression
Pizzagalli, D. A., & Roberts, A. C. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01101-7 · Cited by 667
De Raedt, R., & Koster, E. H. W. (2010) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.10.1.50 · Cited by 583
Functional network dysfunction in anxiety and anxiety disorders
Sylvester, C. M., Corbetta, M., Raichle, M. E., Rodebaugh, T. L., Schlaggar, B. L., Sheline, Y. I., Zorumski, C. F., & Lenze, E. J. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.04.012 · Cited by 579
Self-citationCognitive Mechanisms of Treatment in Depression
Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.183 · Cited by 535
Rive, M. M., van Rooijen, G., Veltman, D. J., .Phillips, M. L., Schene, A. H., & Ruhé, H. G. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.07.018 · Cited by 481
Bipolar and major depressive disorder: Neuroimaging the developmental-degenerative divide
Savitz, J., & Drevets, W. C. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.01.004 · Cited by 494
Anatomical insights into the interaction of emotion and cognition in the prefrontal cortex
Ray, R. D., & Zald, D. H. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.08.005 · Cited by 446
Neurocognitive Mechanisms in Depression: Implications for Treatment
Clark, L., Chamberlain, S. R., & Sahakian, B. J. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125618 · Cited by 446
Phillips, C. (2017) · Neural Plasticity · doi:10.1155/2017/7260130 · Cited by 480
Alexopoulos, G. S., Hoptman, M. J., Kanellopoulos, D., Murphy, C. F., Lim, K. O., & Gunning, F. M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.002 · Cited by 437
Groenewold, N. A., Opmeer, E. M., de Jonge, P., Aleman, A., & Costafreda, S. G. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.11.015 · Cited by 417
A meta-analysis of neurofunctional imaging studies of emotion and cognition in major depression
Diener, C., Kuehner, C., Brusniak, W., Ubl, B., Wessa, M., & Flor, H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.04.005 · Cited by 428
“…striatum (Knutson et al., 2008; Remijnse et al., 2009), thalamus (Fu et al., 2004; Kumari et al., 2003), (para)hippocampal areas (Bremner et al., 2004; Werner et al., 2009), amygdala (Fales et al., 2008; Lee et al., 2008), and additional subcortical and cortical regions (Fitzgerald et al., 2008a).”
D'Angelo, E., & Casali, S. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00116 · Cited by 407
Tartt, A. N., Mariani, M. B., Hen, R., Mann, J. J., & Boldrini, M. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01520-y · Cited by 408
Allostasis and the human brain: Integrating models of stress from the social and life sciences.
Ganzel, B. L., Morris, P., & Wethington, E. (2010) · Psychological Review · doi:10.1037/a0017773 · Cited by 415
“Amygdala hyperexcitability has also been reported in these populations (Dalton et al., 2005; Siegle et al., 2003; Schmahl et al., 2003; Fales et al., 2008; Thomas et al., 2001).”
The effects of child abuse and neglect on cognitive functioning in adulthood
Gould, F., Clarke, J., Heim, C., Harvey, P. D., Majer, M., & Nemeroff, C. B. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.01.005 · Cited by 367
Connolly, C. G., Wu, J., Ho, T. C., Hoeft, F., Wolkowitz, O., Eisendrath, S., Frank, G., Hendren, R., Max, J. E., Paulus, M. P., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.05.036 · Cited by 356
Affective Cognition and its Disruption in Mood Disorders
Elliott, R., Zahn, R., Deakin, J. F. W., & Anderson, I. M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.77 · Cited by 330
Ritchey, M., Dolcos, F., Eddington, K. M., Strauman, T. J., & Cabeza, R. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.09.007 · Cited by 320
Computational psychiatry: towards a mathematically informed understanding of mental illness
Adams, R. A., Huys, Q. J. M., & Roiser, J. P. (2015) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-310737 · Cited by 285
Functional brain imaging studies of youth depression: A systematic review
Kerestes, R., Davey, C. G., Stephanou, K., Whittle, S., & Harrison, B. J. (2013) · NeuroImage Clinical · doi:10.1016/j.nicl.2013.11.009 · Cited by 317
Vialou, V., Bagot, R. C., Cahill, M. E., Ferguson, D., Robison, A. J., Dietz, D. M., Fallon, B., Mazei-Robison, M., Ku, S. M., Harrigan, E., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1787-13.2014 · Cited by 283
McCrory, E. J., & Viding, E. (2015) · Development and Psychopathology · doi:10.1017/s0954579415000115 · Cited by 295
The default mode network and recurrent depression: A neurobiological model of cognitive risk factors
Marchetti, I., Koster, E. H. W., Sonuga-Barke, E. J., & De Raedt, R. (2012) · Neuropsychology Review · doi:10.1007/s11065-012-9199-9 · Cited by 287
Systematic review of the neural basis of social cognition in patients with mood disorders
Cusi, A. M., Nazarov, A., Holshausen, K., MacQueen, G. M., & McKinnon, M. C. (2012) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.100179 · Cited by 278
Fales, C. L., Barch, D. M., Rundle, M. M., Mintun, M. A., Mathews, J., Snyder, A. Z., & Sheline, Y. I. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.04.027 · Cited by 266
Self-citationBrowning, M., Holmes, E. A., & Harmer, C. J. (2010) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.10.1.8 · Cited by 247
Leuchter, A. F., Cook, I. A., Hunter, A. M., Cai, C., & Horvath, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032508 · Cited by 255
Peng, J., Liu, J., Nie, B., Li, Y., Shan, B., Wang, G., & Li, K. (2010) · European Journal of Radiology · doi:10.1016/j.ejrad.2010.04.006 · Cited by 245
Depression: a decision-theoretic analysis
Huys, Q. J. M., Daw, N. D., & Dayan, P. (2015) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-071714-033928 · Cited by 221
Delvecchio, G., Fossati, P., Boyer, P., Brambilla, P., Falkai, P., Gruber, O., Hietala, J. A., Lawrie, S. M., Martinot, J., McIntosh, A. M., et al. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.07.003 · Cited by 234
Enhanced amygdala reactivity to emotional faces in adults reporting childhood emotional maltreatment
van Harmelen, A., van Tol, M., Demenescu, L. R., van der Wee, N. J. A., Veltman, D. J., Aleman, A., van Buchem, M. A., Spinhoven, P., Penninx, B. W. J. H., & Elzinga, B. M. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nss007 · Cited by 247
Sliz, D., & Hayley, S. P. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00323 · Cited by 239
A Neural Biomarker of Psychological Vulnerability to Future Life Stress
Swartz, J. R., Knodt, A. R., Radtke, S. R., & Hariri, A. R. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.055 · Cited by 216
“Thus, relatively greater amygdala reactivity to common stressors could lead to an altered stress response and biased appraisal and memory of stressful events, all of which are core symptoms and features of depression and anxiety disorders (Burke et al., 2005; Espejo et al., 2012; Fales et al., 2008; Hamilton and Gotli…”
Concurrent cognitive control training augments the antidepressant efficacy of tDCS: A pilot study
Segrave, R. A., Arnold, S., Hoy, K., & Fitzgerald, P. B. (2014) · Brain Stimulation · doi:10.1016/j.brs.2013.12.008 · Cited by 244
Imaging phenotypes of major depressive disorder: genetic correlates
Savitz, J. B., & Drevets, W. C. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.03.082 · Cited by 225
Amelioration of Cognitive Control in Depression by Transcranial Direct Current Stimulation
Wolkenstein, L., & Plewnia, C. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.010 · Cited by 213
Optogenetic dissection of medial prefrontal cortex circuitry
Riga, D., Matos, M. R., Glas, A., Smit, A. B., Spijker, S., & Van den Oever, M. C. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00230 · Cited by 208
Sampedro, F., de la Fuente Revenga, M., Valle, M., Roberto, N., Domínguez-Clavé, E., Elices, M., Luna, L. E., Crippa, J. A. S., Hallak, J. E. C., de Araujo, D. B., et al. (2017) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx036 · Cited by 200
Perlman, G., Simmons, A. N., Wu, J., Hahn, K. S., Tapert, S. F., Max, J. E., Paulus, M. P., Brown, G. G., Frank, G. K., Campbell-Sills, L., et al. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.01.044 · Cited by 190
“, 2010), as well as increased amygdala activation among adults with MDD relative to controls (Fales et al., 2008; Matthews et al., 2008).”
Defining Individual-Specific Functional Neuroanatomy for Precision Psychiatry
Gratton, C., Kraus, B. T., Greene, D. J., Gordon, E. M., Laumann, T. O., Nelson, S. M., Dosenbach, N. U. F., & Petersen, S. E. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.10.026 · Cited by 202
The alexithymic brain: the neural pathways linking alexithymia to physical disorders
Kano, M., & Fukudo, S. (2013) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-7-1 · Cited by 210
Pisani, A. R., Wyman, P. A., Petrova, M., Schmeelk-Cone, K., Goldston, D. B., Xia, Y., & Gould, M. S. (2013) · Journal of Youth and Adolescence · doi:10.1007/s10964-012-9884-2 · Cited by 183
Amygdala Volume Marks the Acute State in the Early Course of Depression
van Eijndhoven, P., van Wingen, G. A., van Oijen, K., Rijpkema, M., Goraj, B. M., Verkes, R. J., Voshaar, R. C. O., Fernández, G., Buitelaar, J. K., & Tendolkar, I. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.10.027 · Cited by 181
Adolescents with major depression demonstrate increased amygdala activation
Yang, T. T., Simmons, A. N., Matthews, S. C., Tapert, S. F., Frank, G. K., Max, J. E., Bischoff-Grethe, A., Lansing, A. E., Brown, G., Strigo, I. A., et al. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2009.09.004 · Cited by 176
“This finding is consistent ith adult positron emission tomographic(5) and MRI studies.(6,7,39,40) This result is also consistent ith the majority of fMRI pediatric depression tudies.”
Emotion modulates cognitive flexibility in patients with major depression
Murphy, F. C., Michael, A., & Sahakian, B. J. (2011) · Psychological Medicine · doi:10.1017/s0033291711002418 · Cited by 186
Association between abnormal default mode network activity and suicidality in depressed adolescents
Zhang, S., Chen, J.-M., Kuang, L., Cao, J., Zhang, H., Ai, M., Wang, W., Zhang, S.-D., Wang, S.-Y., Liu, S.-J., et al. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1047-7 · Cited by 163
Intrinsic connectomes are a predictive biomarker of remission in major depressive disorder
Korgaonkar, M. S., Goldstein-Piekarski, A. N., Fornito, A., & Williams, L. M. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0574-2 · Cited by 163
Tendolkar, I., Beek, M. H. C. T. V., van Oostrom, I., Mulder, M., Janzing, J., Voshaar, R. C. O., & van Eijndhoven, P. (2013) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2013.09.004 · Cited by 165
An Improved Empirical Mode Decomposition of Electroencephalogram Signals for Depression Detection
Shen, J. G., Zhang, X., Wang, G., Ding, Z., & Hu, B. (2019) · IEEE Transactions on Affective Computing · doi:10.1109/taffc.2019.2934412 · Cited by 163
Distracted and down: neural mechanisms of affective interference in subclinical depression
Kaiser, R. H., Andrews-Hanna, J. R., Spielberg, J. M., Warren, S. L., Sutton, B. P., Miller, G. A., Heller, W., & Banich, M. T. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsu100 · Cited by 147
Comte, M., Schön, D., Coull, J. T., Reynaud, E., Khalfa, S., Belzeaux, R., Ibrahim, E. C., Guedj, E., Blin, O., Weinberger, D. R., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhu185 · Cited by 142
Imbalanced Neural Responsivity to Risk and Reward Indicates Stress Vulnerability in Humans
Admon, R., Lubin, G., Rosenblatt, J. D., Stern, O., Kahn, I., Assaf, M., & Hendler, T. (2013) · Cerebral Cortex · doi:10.1093/cercor/bhr369 · Cited by 143
State-dependent alteration in face emotion recognition in depression
Anderson, I. M., Shippen, C., Juhasz, G., Chase, D., Thomas, E., Downey, D., Toth, Z. G., Lloyd-Williams, K., Elliott, R., & Deakin, J. F. W. (2011) · British Journal of Psychiatry · doi:10.1192/bjp.bp.110.078139 · Cited by 143
Cognitive and default‐mode resting state networks: Do male and female brains “rest” differently?
Weissman‐Fogel, I., Moayedi, M., Taylor, K. S., Pope, G. E., & Davis, K. D. (2010) · Human Brain Mapping · doi:10.1002/hbm.20968 · Cited by 147
A review of fMRI studies during visual emotive processing in major depressive disorder
Jaworska, N., Yang, X.-R., Knott, V., & MacQueen, G. (2015) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2014.885659 · Cited by 133
Tao, J., Chen, X., Egorova, N., Liu, J., Xue, X., Wang, Q., Zheng, G., Li, M., Hong, W., Sun, S., et al. (2017) · Scientific Reports · doi:10.1038/srep41581 · Cited by 147
De Raedt, R., Leyman, L., Baeken, C., Van Schuerbeek, P., Luypaert, R., Vanderhasselt, M.-A., & Dannlowski, U. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.09.015 · Cited by 135
Neural substrates of trait ruminations in depression.
Mandell, D., Siegle, G. J., Shutt, L. S., Feldmiller, J., & Thase, M. E. (2014) · Journal of Abnormal Psychology · doi:10.1037/a0035834 · Cited by 144
Yao, S., Xu, M.-D., Wang, Y., Zhao, S., Wang, J., Chen, G.-F., Chen, W., Liu, J., Huang, G., Sun, W.-J., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36209-5 · Cited by 144
Dichter, G. S., Felder, J. N., & Smoski, M. J. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.03.022 · Cited by 139
“Unipolar MDD is characterized by de fi cits in cognitive control and hyper-responsivity to sad events that have been linked to prefrontal and limbic dysfunction, respectively (Clark et al., 2009; Fales et al., 2008; Grimm et al., 2008; Halari et al., 2009; Holmes and Pizzagalli, 2008).”
Jin, C., Gao, C., Chen, C., Ma, S., Netra, R., Wang, Y., Zhang, M., & Li, D. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.08.017 · Cited by 136
Bertocci, M. A., Bebko, G. M., Mullin, B. C., Langenecker, S. A., Ladouceur, C. D., Almeida, J., & Phillips, M. L. (2011) · Psychological Medicine · doi:10.1017/s003329171100242x · Cited by 137
“…stimuli, but less consistently to positive emotional stimuli (Fu et al. 2004 ; Surguladze et al. 2005 ; Anand et al. 2007; Dannlowski et al. 2007 ; Fales et al. 2008), and abnormally reduced activity in the striatum to positive emotional and rewarding stimuli (Surguladze et al. 2005 ; Epstein et…”
InfluentialNjau, S. N., Joshi, S. H., Espinoza, R. T., Leaver, A. M., Vasavada, M. M., Marquina, A., Woods, R. P., & Narr, K. L. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.150177 · Cited by 134
McCrory, E. J. P., Foulkes, L., & Viding, E. M. (2022) · The Lancet Psychiatry · doi:10.1016/s2215-0366(22)00202-4 · Cited by 147
Zhao, J., Mo, L., Bi, R., He, Z., Chen, Y., Xu, F., Xie, H., & Zhang, D. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1906-20.2020 · Cited by 136
Hwang, J. W., Egorova, N., Yang, X., Zhang, W. Y., Chen, J., Yang, X., Hu, L., Sun, S., Tu, Y., & Kong, J. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.174 · Cited by 138
Pourtois, G., Vocat, R., N’Diaye, K., Spinelli, L., Seeck, M., & Vuilleumier, P. O. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.12.020 · Cited by 128
In Search of Neural Endophenotypes of Postpartum Psychopathology and Disrupted Maternal Caregiving
Moses‐Kolko, E. L., Horner, M. S., Phillips, M. L., Hipwell, A. E., & Swain, J. E. (2014) · Journal of Neuroendocrinology · doi:10.1111/jne.12183 · Cited by 134
The neural systems of emotion regulation and abnormalities in major depressive disorder
Park, C., Rosenblat, J. D., Lee, Y. L., Pan, Z., Cao, B., Iacobucci, M., & McIntyre, R. S. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.04.002 · Cited by 142
Butterfield, R. D., Silk, J. S., Lee, K. H., Siegle, G. J., Dahl, R. E., Forbes, E. E., Ryan, N. D., Hooley, J. M., & Ladouceur, C. D. (2020) · Development and Psychopathology · doi:10.1017/s0954579419001718 · Cited by 136
Abnormal neural filtering of irrelevant visual information in depression
Desseilles, M., Balteau, E., Sterpenich, V., Dang-Vu, T. T., Darsaud, A., Vandewalle, G., Albouy, G., Salmon, E., Peters, F., Schmidt, C., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3341-08.2009 · Cited by 129
Kerestes, R., Ladouceur, C. D., Meda, S., Nathan, P. J., Blumberg, H. P., Maloney, K., Ruf, B., Saricicek, A., Pearlson, G. D., Bhagwagar, Z., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291711001097 · Cited by 128
Gudayol‐Ferré, E., Peró, M., González‐Garrido, A. A., & Guàrdia‐Olmos, J. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00582 · Cited by 135
The cholinergic system and depression
Dagytė, G., den Boer, J. A., & Trentani, A. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.02.023 · Cited by 127
Disner, S. G., Beevers, C. G., & Gonzalez-Lima, F. (2016) · Brain stimulation · doi:10.1016/j.brs.2016.05.009 · Cited by 127
“Considering that hypoactivity in the prefrontal cortex has been associatedwith negative attentional bias [39–42], and considering that LLLT has been linked to increased cytochrome oxidase activity, improved cognitive function, and decreased negative affect [35,43], there is strong reason to believe that LLLT to the pr…”
Harlé, K. M., Chang, L. J., Wout‐Frank, M. V. ‘., & Sanfey, A. G. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.02.027 · Cited by 139
Pirnia, T., Joshi, S. H., Leaver, A. M., Vasavada, M., Njau, S., Woods, R. P., Espinoza, R., & Narr, K. L. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.102 · Cited by 122
Functional Connectivity of the Amygdala in Early-Childhood-Onset Depression
Luking, K. R., Repovš, G., Belden, A. C., Gaffrey, M. S., Botteron, K. N., Luby, J. L., & Barch, D. M. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2011.07.019 · Cited by 124
Self-citationOrbitofrontal volume reductions during emotion recognition in patients with major depression
Scheuerecker, J., Meisenzahl, E. M., Koutsouleris, N., Roesner, M., Schöpf, V., Linn, J., Wiesmann, M., Brückmann, H., Möller, H.-J., & Frodl, T. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090076 · Cited by 124
“Decreased right activity in the dorsolateral prefrontal cortex was detected in a study using an attentional interference task in 27 patients with major depression compared with 24 healthy controls.(53) Activity in the left dorsolateral prefrontal cortex was reduced during cognitive (digit sorting) and emotional (perso…”
Wang, L., Li, K., Zhang, Q., Zeng, Y., Dai, W., Su, Y., Wang, G., Tan, Y., Jin, Z. H., Yu, X., et al. (2013) · Psychological Medicine · doi:10.1017/s0033291713002031 · Cited by 120
Neuroimaging and Depression: Current Status and Unresolved Issues
Gotlib, I. H., & Hamilton, J. P. (2008) · Current Directions in Psychological Science · doi:10.1111/j.1467-8721.2008.00567.x · Cited by 134
Su, Y. A., Wu, J., Zhang, L., Zhang, Q., Su, D. M., He, P., Wang, B.-D., Li, H., Webster, M. J., Group, T. S. B. S., et al. (2008) · International Journal of Biological Sciences · doi:10.7150/ijbs.4.223 · Cited by 113
Bruce, S. E., Buchholz, K. R., Brown, W. J., Yan, L., Durbin, A., & Sheline, Y. I. (2013) · NeuroImage: Clinical · doi:10.1016/j.nicl.2012.11.003 · Cited by 113
Self-citationGender Differences in Cognitive Control: an Extended Investigation of the Stop Signal Task
Li, C. R., Zhang, S., Duann, J., Yan, P., Sinha, R., & Mazure, C. M. (2009) · Brain Imaging and Behavior · doi:10.1007/s11682-009-9068-1 · Cited by 120
Biomarkers for major depressive disorder
Hacımusalar, Y., & Eşel, E. (2017) · Nöro Psikiyatri Arşivi · doi:10.5152/npa.2017.19482 · Cited by 123
Incongruence effects in crossmodal emotional integration
Müller, V. I., Habel, U., Derntl, B., Schneider, F. W., Zilles, K., Turetsky, B. I., & Eickhoff, S. B. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.10.047 · Cited by 118
Culbreth, A. J., Moran, E. K., & Barch, D. M. (2017) · Psychological Medicine · doi:10.1017/s0033291717002525 · Cited by 121
Self-citationMaalouf, F. T., Klein, C., Clark, L., Sahakian, B. J., LaBarbara, E. J., Versace, A., Hassel, S., Almeida, J., & Phillips, M. L. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.02.015 · Cited by 114
“…in both bipolar disorder and unipolar depression, and are consistent with neuroimaging studies reporting abnormal activity in these regions during emotion regulation tasks in both bipolar depressed (Deckersbach et al., 2008) and unipolar depressed adults (Fales et al., 2008; Siegle et al., 2002).”
van Vugt, M. K., Hitchcock, P., Shahar, B., & Britton, W. B. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00257 · Cited by 114
Metadata
- Authors
- Fales, C. L., Barch, D. M., Rundle, M. M., Mintun, M. A., Snyder, A. Z., Cohen, J. D., Mathews, J., & Sheline, Y. I.
- Affiliations
- Washington University in St. Louis (US)
- Princeton University (US)
- Corresponding author
- Sheline, Yvette I.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-02
- Volume
- 63
- Issue
- 4
- Pages
- 377-384
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC2268639
- OpenAlex
- W2161710337
- Cited by
- 517
- References
- 55
- Citations by year
- 2026: 9 · 2025: 21 · 2024: 32 · 2023: 20 · 2022: 21 · 2021: 57 · 2020: 27 · 2019: 22 · 2018: 15 · 2017: 30 · 2016: 35 · 2015: 35 · 2014: 34 · 2013: 27 · 2012: 38
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH066031, R01 MH06603101, R01 MH64821, R01MH064821)
- National Center for Research Resources (K24 RR18192, K24RR018192)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- major depressive disorder, negativity bias, emotional interference, attentional interference, top-down cognitive control, amygdala, dorsolateral prefrontal cortex, anterior cingulate cortex, emotional distracters, event-related fMRI
- MeSH terms
- Adult, Affect, Amygdala, Attention, Cognition, Cognition Disorders, Depressive Disorder, Major, Major Depressive Disorder, Face, Fear, Female, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Nerve Net, Neuropsychological Tests, Surveys and Questionnaires, Visual Perception
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