The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract
Abstract
Olive leaves, an agricultural waste, have great potential as a natural antioxidant. The current study was made to assess the antioxidant and antimicrobial activities of both the individual and combined phenolics in olive leaf extract. A combined phenolics mixture was prepared by amount ratios of the phenolic compounds in the olive leaf extract. The results showed that both the individual and combined phenolics exhibited good radical scavenging abilities, and also revealed superoxide dismutase (SOD)-like activity. In terms of antimicrobial activity, both oleuropein and caffeic acid showed inhibition effects against microorganisms. Furthermore, the antimicrobial effect of the combined phenolics was significantly higher than those of the individual phenolics. These results show that the combination of olive leaf extract phenolics possessed antioxidant and antimicrobial activities. This study indicates that olive leaf extract might be a valuable bioactive source, and would seem to be applicable in both the health and medical food.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Additionally, in general, in the mixed form, individual components can modify their properties and interact synergistically, producing improved effects [18,25,39].”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [18]
In the citing paper
“Studies report that the antimicrobial and antioxidant efficiency of the olive leaf extracts are directly related with their content of polyphenols [18,20,33,34].”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [18]
In the citing paper
“Some studies have already reported the antioxidant capacity of olive [17,18,22] and mimosa leaf [8,71] extracts.”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [18]
In the citing paper
“Among all by-products, olives leaves have attracted growing attention as they contain an array of simple phenolics (phenylethanoids, hydroxybenzoic acids, and hydroxycinnamic acids) and polyphenolic compounds (secoiridoids and flavonoids) with biological properties, including antioxidant and antimicrobial [16,17,18,19,20,21,22,23].”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [18]
Citations
Cites
Barr, A. J. (1979) · Medical Entomology and Zoology · Cited by 7,198
Škerget, M., Kotnik, P., Hadolin, M., Hraš, A. R., Simonič, M., & Knez, Ž. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.02.025 · Cited by 1,182
Antioxidant activity of phenolics extracted from Olea europaea L. leaves
Benavente-Garcı́a, O., Castillo, J., Lorente, J., Ortuño, A., & Del Rio, J. A. (2000) · Food Chemistry · doi:10.1016/s0308-8146(99)00221-6 · Cited by 867
Somova, L. I., Shode, F. O., Ramnanan, P., & Nadar, A. (2003) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(02)00332-x · Cited by 383
Antimicrobial activity of commercial Olea europaea (olive) leaf extract
Sudjana, A. N., D’Orazio, C., Ryan, V., Rasool, N., Ng, J., Islam, N., Riley, T. V., & Hammer, K. A. (2009) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2008.10.026 · Cited by 325
INHIBITION OF N‐NITROSAMINE FORMATION IN MODEL FOOD SYSTEMS
Gray, J., & Dugan, L. R. (1975) · Journal of Food Science · doi:10.1111/j.1365-2621.1975.tb02248.x · Cited by 255
Lee, O.-H., Lee, B.-Y., Lee, J., Lee, H.-B., Son, J.-Y., Park, C.-S., Shetty, K., & Kim, Y.-C. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.06.059 · Cited by 231
Biophenolic components of olives
Bianco, A., & Uccella, N. (2000) · Food Research International · doi:10.1016/s0963-9969(00)00072-7 · Cited by 190
Gucci, R., Lombardini, L., & Tattini, M. (1997) · Tree Physiology · doi:10.1093/treephys/17.1.13 · Cited by 186
Khayyal, M. T., El‐Ghazaly, M. A., Abdallah, D., Nassar, N. N., Okpanyi, S. N., & Kreuter, M.-H. (2011) · Arzneimittelforschung · doi:10.1055/s-0031-1299970 · Cited by 165
Flagged first, then by citations
Cited by
Sorted by citations
Items 201–300 of 380
Machado, N. D., Bastante, C. C., Goñi, M. L., Gañán, N. A., Casas, L., & Mantell, C. (2022) · Antioxidants · doi:10.3390/antiox11061170 · Cited by 16
“Many plant extracts have potential beneficial therapeutic effects which generally are a consequence of a synergistic activity among their bioactive components [34,35].”
BackgroundFacile green synthesis inorganic cuprous oxide nanoparticles and their antibacterial properties
Binjawhar, D. N., Alsharari, S. S., balawi, A. N. A., Abdulhasan, M. J., Khat, M., & Ameén, F. (2023) · Micro & Nano Letters · doi:10.1049/mna2.12154 · Cited by 16
Dağdelen, A. (2016) · Journal of Chemistry · doi:10.1155/2016/9589763 · Cited by 16
Alpaslan, D., Dudu, T. E., & Aktaş, N. (2018) · DergiPark (Istanbul University) · Cited by 16
Baharvand-Ahmadi, B., Esmailidehaj, M., Alihosaini, J., Bajoovand, S., Esmailidehaj, S., & Hafizibarjin, Z. (2016) · PubMed Central · doi:10.7508/ibj.2016.01.006 · Cited by 16
“Several studies have reported the beneficial effects of oleuropein including anti-diabetic [30] , anti-inflammatory [31] , anti-apoptotic [15] , anti-infarct [13] , and antimicrobial [32] effcets, and protection of the skin against ultraviolet ray [33,34] etc.”
BackgroundTaviano, M. F., Melchini, A., Filocamo, A., Costa, C., Catania, S., Raciti, R., Saha, S., Needs, P. W., Bisignano, G., & Miceli, N. (2017) · Pharmacognosy Magazine · doi:10.4103/pm.pm_245_16 · Cited by 16
la Ossa, J. G. D., Kadri, H. E., Gutierrez‐Merino, J., Wantock, T., Harle, T., Seggiani, M., Danti, S., Stefano, R. D., & Velliou, E. G. (2021) · Molecules · doi:10.3390/molecules26071890 · Cited by 16
“According to some studies, OLE exerts antimicrobial effects due to its high phenolic content [16,23,24].”
BackgroundEVALUATION OF ANTIMICROBIAL ACTIVITY IN OLIVE (OLEA EUROPAEA) LEAF EXTRACT
Gökmen, M., Kara, R., Akkaya, L., Torlak, E., & Önen, A. (2014) · Current Research in Microbiology · doi:10.3844/ajmsp.2014.37.40 · Cited by 16
“Similarly, Lee and Lee (2010) reported that the combined phenolics mixture which was prepared from olive leaf extract showed inhibition effects against B. cereus and S. enteritidis.”
BackgroundResultPhytochemicals as Anti-microbial Food Preservatives
Tajkarimi, M. M., & Ibrahim, S. A. (2012) · Springer eBooks · doi:10.1007/978-94-007-3926-0_7 · Cited by 16
Casado‐Díaz, A., Torre, M. L., Priego‐Capote, F., Soriano, J. V., Lázaro‐Martínez, J. L., Rodríguez‐Mañas, L., Berenguer‐Pérez, M., & Túnez, I. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051229 · Cited by 15
“OELE phenolic compounds have a synergistic effect on antioxidant capacity when they are together in the extract compared to their individual effects [58].”
BackgroundAgatonović-Kuštrin, S., Gegechkori, V., Morton, D. W., Tucci, J., Mohammed, E. U. R., & Ku, H. (2022) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2022.114916 · Cited by 15
Vidičević, S., Tasić, J., Stanojević, Ž., Isaković, A., Mitić, D. M., Ristić, D., & Dekanski, D. (2019) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2018.1550095 · Cited by 15
Classification, Biotransformation and Antioxidant Activity of Olive Fruit Biophenols: A Review
Goulas, V., Charisiadis, P., Gerothanassis, I. P., & Manganaris, G. Α. (2012) · Current Bioactive Compounds · doi:10.2174/157340712802762465 · Cited by 15
“A plethora of studies have been published concerning the antioxidant activity of oleuropein and its derivatives [4, 9, 10]; the antimicrobial [11, 12], antiviral [13], anti-atherogenic and anti-inflammatory activity of oleuropein have also been reported [9, 11].”
BackgroundEffect of the Olive Leaf Extracts In Vitro and in Active Packaging of Sliced Iberian Pork Loin
Delgado, J., Bote, E., Parra‐Testal, V., Martín, M. J., & Ramírez, R. (2016) · Packaging Technology and Science · doi:10.1002/pts.2267 · Cited by 15
“Actually, the antibacterial activity in vitro of some phenolic compounds present in olive leaves, such as oleuropein, rutin, vanillin and caffeic acid, has been investigated.(20) In addition, these phenolic compounds combined have similar or better effects than individually.”
BackgroundInfluentialKaviani, M., Sepasi, S., Azima, S., Emamghoreishi, M., Asadi, N., & Haghpanah, S. (2017) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2017v9i7.15387 · Cited by 15
“hydroxytyrosol, and oleanolic acid, possesses antimicrobial and antioxidant activities [8-10].”
BackgroundPopović, M., Špika, M. J., Bratinčević, M. V., Ninčević, T., Matešković, A., Mandušić, M., Rošin, J., Nazlić, M., Dunkić, V., & Vitanović, E. (2021) · Molecules · doi:10.3390/molecules26123533 · Cited by 15
Topalović, D., Živković, L., Pirković, A., Djelić, N., Bajić, V., Dekanski, D., & Spremo‐Potparević, B. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/762192 · Cited by 14
“The effect of the combined phenolics was significantly higher than that of the individual constituents [23, 48].”
BackgroundOptimization of the sugar hydrothermal extraction process from olive cake using neuro-fuzzy models
Pérez, A., Blázquez, G., Iáñez-Rodríguez, I., Osegueda, O., & Calero, M. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.07.136 · Cited by 14
Ghelichpour, M., Mirghaed, A. T., Dawood, M. A. O., Hoseinifar, S. H., & Doan, H. V. (2020) · Aquaculture Research · doi:10.1111/are.14964 · Cited by 14
Gómez, I., García-Varona, C., Curiel-Fernández, M., & Ortega-Herás, M. (2020) · Foods · doi:10.3390/foods9121728 · Cited by 14
“Extracts obtained from olives contain significant amounts of water-soluble polyphenols, among which hydroxytyrosol stands out [11,12].”
BackgroundAlbertos, I., Martín‐Diana, A. B., Jaime, I., Avena‐Bustillos, R. J., McHugh, T. H., Takeoka, G. R., Dao, L., & Rico, D. (2017) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.13397 · Cited by 14
Yuan, J., Tu, J., Qin, F. G. F., Xu, Y., & Li, B. (2018) · Journal of Food Biochemistry · doi:10.1111/jfbc.12517 · Cited by 14
Jia, P., Wang, Y., Niu, Y., Han, X., Zhu, Y., Xu, Q., Li, Y., & Peng, C. (2019) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2019.08.016 · Cited by 14
“Rutin has been used in pharmaceutical drugs because of its antibacterial (Lee and Lee, 2010), antihyperglycaemic (Calzada et al., 2017) and antioxidative properties (Yang et al., 2008).”
Backgroundda Silva, P. S., Viell, F. L. G., Ineu, R. P., Bona, E., Días, M. I., Ferreira, I. C. F. R., Barros, L., Gonçalves, O. H., Leimann, F. V., & Cardozo‐Filho, L. (2022) · Brazilian Journal of Chemical Engineering · doi:10.1007/s43153-022-00268-w · Cited by 13
de Souza, J. G. D. L., Toledo, A. G., Santana, C. B., dos Santos, C. V., Mallmann, A. P., da Silva, J. P. B., & Pinto, F. G. D. S. (2017) · Revista Brasileira de Saúde e Produção Animal · doi:10.1590/s1519-99402017000300005 · Cited by 13
Sharma, R., & Kaur, R. (2019) · International Journal of Environmental Science and Technology · doi:10.1007/s13762-019-02491-4 · Cited by 13
“2001; Lee and Lee 2010).”
Alqurashi, R. M., & Aldossari, H. (2021) · Emirates Journal of Food and Agriculture · doi:10.9755/ejfa.2021.v33.i6.2711 · Cited by 13
“Some of the phytochemical compounds present in many plants have previously been reported to have antimicrobial and antifungal activities, as well as substantial natural antioxidant effects (Chibane et al., 2019; Lee and Lee, 2010).”
BackgroundSarıca, Ş., Özdemir, D., & Öztürk, H. (2015) · Italian Journal of Animal Science · doi:10.4081/ijas.2015.3737 · Cited by 13
“…of the bioactive polyphenolic compounds in the olive leaves extract to act as a free radical scavenger is partly related to their standard one-electron reduction potential by either donating hydrogen or electron or breaking the free radical chain reaction (Hayes et al., 2011; Lee and Lee, 2010).”
BackgroundTopical Olive Leaf Extract Improves Healing of Oral Mucositis in Golden Hamsters.
Showraki, N., Mardani, M., Emamghoreishi, M., Andisheh‐Tadbir, A., Aram, A., Mehriar, P., Omidi, M., Sepehrimanesh, M., Koohi‐Hosseinabadi, O., & Tanideh, N. (2016) · PubMed Central · Cited by 13
Attia, T. B., Ali, R. B., Nahdi, A., Galaï, S., Ghali, R., Rammeh, S., may, M. V. E., & Mhamdi, A. (2023) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2023.06.016 · Cited by 12
“Moreover, research findings suggest that phenolic compounds exhibit a synergistic effect on antioxidant capacity when present together, such as in OLE, which is greater than the sum of their individual effects (Xie et al, 2015, Lee & Lee 2010).”
Çetinkaya, H., & Kulak, M. (2016) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.21010/ajtcam.v13i2.10 · Cited by 12
“In these phenolics, the combined phenolic compounds have substantial high antimicrobial activity than the others (Lee and Lee, 2010).”
BackgroundAntifungal Activity of Monoterpenes against Botryosphaeria dothidea
Zhang, Z., Xie, Y., Hu, X. G., Shi, H., Wei, M., & Lin, Z. (2018) · Natural Product Communications · doi:10.1177/1934578x1801301234 · Cited by 11
“By comparing our results with those reported by Lee and Lee [25] that synergic behavior of olive leaf extracts, whereas the combined phenolics exhibited a strong antifungal activity than the individual phenolics.”
ResultSoriano, J. V., de Cristino-Espinar, M., Luna-Morales, S., Guerra, C. D., Casado‐Díaz, A., Quesada‐Gómez, J. M., Dorado, G., Berenguer‐Pérez, M., Vílchez, S., Esquena, J., et al. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15071925 · Cited by 11
“Oleuropein is the most abundant phenolic compound in OELE, followed by hydroxytyrosol, oleuropein, aglycone, and tyrosol, with the antioxidant activity of them being synergistic [53].”
BackgroundAttia, T. B., Bahri, S., Younes, S. B., Nahdi, A., Ali, R. B., Kacem, L. B. H., May, M. V. E., López‐Maldonado, E. A., & Mhamdi, A. (2024) · Biology · doi:10.3390/biology13110896 · Cited by 11
“Furthermore, when these phenolic compounds are combined, they can exhibit synergistic effects, significantly enhancing the antioxidant capacity beyond the cumulative impact of each compound [23].”
Tarchi, I., Olewnik‐Kruszkowska, E., Aït‐Kaddour, A., & Bouaziz, M. A. (2025) · ACS Omega · doi:10.1021/acsomega.4c10858 · Cited by 11
“64 In a previous study, Lee & Lee 64 had reported that olive leaves have a high natural biological capacity.”
Cabrera–Vique, C., Navarro‐Alarcón, M., Martínez, C. R., & Fonollá-Joya, J. (2015) · PubMed · doi:10.3305/nh.2015.32.1.8644 · Cited by 11
The effect of olive (Olea europaea L.) phenolics and sugar on Drosophila melanogaster’s development
Güneş, E., & Arslan, D. (2018) · Animal Biology · doi:10.1163/15707563-17000162 · Cited by 11
Yang, D., & Ouyang, M. (2012) · International Journal of Organic Chemistry · doi:10.4236/ijoc.2012.24054 · Cited by 11
“There is report both the individual and combined phenolics exhibited good radical scavenging abilities [5], and the relative abilities of the flavonoids from olive leaf to scavenge the ABTS radical cation are influenced by the presence of functional groups in their structure [6].”
Sierżant, K., Orda, J., Korzeniowska, M., & Malicki, A. (2018) · Medycyna Weterynaryjna · doi:10.21521/mw.6143 · Cited by 10
“Although complex mixtures of polyphenols generally exhibit higher antimicrobial activity than their individual components (20), highly purified plant extract constituents can also potentially be used as effective growth promoters.”
BackgroundKhozeimeh, F., Golestannejad, Z., Abtahi, R., Zarei, Z., Sadeghalbanaei, L., & Sadeghian, R. (2020) · Dental Research Journal · doi:10.4103/1735-3327.284730 · Cited by 10
Antibacterial activities of polyphenols from olive leaves against Klebsiella pneumoniae
Yuan, J., Yan, H.-J., He, J., & Liu, Y. (2021) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/680/1/012060 · Cited by 10
“They exhibit a range of biological activities, such as an antioxidant activity (2,2-diphenyl-1-picrylhydrazyl [DPPH] radical scavenging and reducing power) [2], an anticancer activity [3], and an antimicrobial activity against Helicobacter pylori, Campylobacter jejuni, Staphylococcus aureus [4], Bacillus cereus, Esche…”
BackgroundMartiny, T. R., Dotto, G. L., Raghavan, V., Moraes, C. C., & da Rosa, G. S. (2021) · International Journal of Environmental Science and Technology · doi:10.1007/s13762-021-03732-1 · Cited by 10
“Researchers have studied its antioxidant activity (Lee and Lee 2010) and antimicrobial activity (Sudjana et al.”
BackgroundKeceli, T. M., & Harp, F. (2014) · Quality Assurance and Safety of Crops & Foods · doi:10.3920/qas2013.0305 · Cited by 10
Pietsch, K., Hofmann, S., Henkel, R., Saul, N., Menzel, R., & Steinberg, C. E. W. (2010) · Fresenius environmental bulletin · Cited by 10
Idm’hand, E., Msanda, F., & Cherifi, K. (2019) · International Journal of Pharmacology Phytochemistry and Ethnomedicine · doi:10.18052/www.scipress.com/ijppe.14.16 · Cited by 11
Al‐Rimawi, F., Sbeih, M., Amayreh, M., Rahhal, B., & Mudalal, S. (2024) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2024.102014 · Cited by 9
“Several researchers found that olive leaf extract has antibacterial and antifungal properties (Kor-ukluoglu et al., 2008, Lee and Lee, 2010; Borjan et al., 2020).”
BackgroundSoriano, J. V., Casado‐Díaz, A., de Cristino-Espinar, M., Luna-Morales, S., Guerra, C. D., Moreno-Moreno, P., Dorado, G., Quesada‐Gómez, J. M., Rodríguez‐Mañas, L., & Lázaro‐Martínez, J. L. (2023) · Gels · doi:10.3390/gels9120962 · Cited by 9
“Besides, their antioxidant activity is synergistic [35].”
Treatment of genital herpes using olive leaf extract
Lorzadeh, N., Kazemirad, Y., & Kazemirad, N. (2020) · Clinical Case Reports · doi:10.1002/ccr3.3723 · Cited by 9
Alfifi, A., El-Hamid, M. I. A., Abdel-Raheem, S. M., Al-Khalaifah, H. S., Youssef, W., Khalil, S. S., Al-Nasser, A. Y., Elkhawaga, E., Elmehrath, E. M. A., Nassar, A. H., et al. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-04663-6 · Cited by 8
“The polyphenolic components of OLE can scavenge free radicals, disrupt the free radical chain reaction [20], as well as suppress the metal ion chelation, which may contribute to the antioxidant characteristics of OLE [21].”
Rong, J., Han, Y., Zha, S., Tang, Y., Shi, W. M., Guan, X., Du, X., He, M., & Liu, G. (2020) · Journal of Ocean University of China · doi:10.1007/s11802-020-4232-8 · Cited by 8
“However, only the immunomodulatory effects of phenols and flavonoids of OE have been elucidated to date (Benavente-Garcı́a et al., 2000; McDonald et al., 2001; Lee and Lee, 2010), leaving the function of terpenoids such as triterpenes largely less looked.”
BackgroundZhu, L., Wei, Q., Porchas, M., Brierley, P., Friedman, M., Crosby, K. M., Patil, B. S., & Ravishankar, S. (2021) · Food Microbiology · doi:10.1016/j.fm.2021.103876 · Cited by 8
Mkaouar, S., Charfi, B., Tounsi, L., Bahloul, N., Allaf, K. S., & Kechaou, N. (2022) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-021-01257-2 · Cited by 8
“Olive leaves are shown to have beneficial impacts on human health, thanks to phenolic compounds, in particular oleuropein [4–6], which possess antioxidant [7, 8], anticancer [9, 10], hypoglycemic [11, 12], cardioprotective [13], neuroprotective [14, 15] and antimicrobial [8, 16, 17] activities.”
BackgroundSAMANCIOĞLU, S., Esen, A., Ercan, G., Mansoub, N. H., Vatansever, S., & İnce, İ. (2016) · European Journal of Therapeutics · doi:10.5578/gmj.27960 · Cited by 8
“Oleuropein is a natural antimicrobial and it has been shown in various studies that it delays and inhibits the growth rate of microorganisms (33-36).”
BackgroundTorrecillas-Baena, B., Camacho-Cardeñosa, M., Carmona-Luque, M. D., Dorado, G., Berenguer‐Pérez, M., Quesada‐Gómez, J. M., Gálvez-Moreno, M. Á., & Casado‐Díaz, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713328 · Cited by 9
“Moreover, the antioxidant activity of these compounds is synergistic [17].”
BackgroundRaut, P., Dhawale, S. C., Kulkarni, D. A., Pekamwar, S. S., Shelke, S., Panzade, P. S., & Paliwal, A. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-021-00185-8 · Cited by 8
Öztürk, G., Yetiman, A. E., & Doğan, M. (2019) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-019-00041-7 · Cited by 7
Especies vegetales como antioxidantes de alimentos
Bisbal, J. J. S., Lloret, J. M., Lozano, G. M., & Fagoaga, C. (2020) · Nereis Interdisciplinary Ibero-American Journal of Methods Modelling and Simulation · doi:10.46583/nereis_2020.12.577 · Cited by 7
Antioxidant actions of olive leaf extract (Olea europaea L.) on reactive species scavengers
de Melo, M. P. (2020) · Journal of Analytical & Pharmaceutical Research · doi:10.15406/japlr.2020.09.00354 · Cited by 7
Pandiyan, P., Soni, A., & Elumalai, P. (2021) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.15952 · Cited by 7
RetractedJaskiw, G. E., Xu, D., Obrenovich, M. E., & Donskey, C. J. (2022) · Metabolomics · doi:10.1007/s11306-021-01866-4 · Cited by 7
Effects of different drying conditions on bioactive potential of Brazilian olive leaf
Cagliari, A., Martiny, T. R., Nascimento, R., Morais, M. M., & da Rosa, G. S. (2022) · Brazilian journal of food technology/Brazilian Journal of Food Technology · doi:10.1590/1981-6723.14721 · Cited by 7
Mahdavi, F. S., Mardi, P., Mahdavi, S. S., Kamalinejad, M., Hashemi, S. A., Khodaii, Z., & Natanzi, M. M. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/6669813 · Cited by 7
“, especially the oleuropein, are associated with antioxidant, antihypertensive, hypoglycemic, hypocholesterolemia, and cardioprotective activity [30, 31].”
BackgroundDoğal Bir Antimikrobiyel: Oleuropein
Yıldız, G., & Uylaşer, V. (2011) · DergiPark (Istanbul University) · Cited by 7
Lahcene, S., Moualek, I., Bariz, K., Benramdane, E., Alenazy, R., Alqasmi, M. H., Almufarriji, F. M., Thabet, M. A., Fallata, G., Alqurainy, N., et al. (2025) · Processes · doi:10.3390/pr13041113 · Cited by 6
Thapa, K., Julianingsih, D., Tung, C., Phan, A., Hashmi, M. A., Bleich, K., & Biswas, D. (2024) · Foods · doi:10.3390/foods13172746 · Cited by 6
Revealing the molecular mechanism of Olea europaea L. in treatment of cataract
Badria, F. A.-E., & Elgazar, A. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819528-4.00008-0 · Cited by 6
Aljeddani, G. S. (2022) · Natural Science · doi:10.4236/ns.2022.1410039 · Cited by 6
Nasirzadeh, M., & Rasouli, A. (2015) · International Journal of Women s Health and Reproduction Sciences · doi:10.15296/ijwhr.2016.18 · Cited by 6
Utilization of By‐Products from Food Processing as Biofertilizers and Biopesticides
Datta, A., Ullah, H., & Ferdous, Z. (2017) · Wiley eBooks · doi:10.1002/9781118432921.ch8 · Cited by 6
Jiang, Y., Wang, X., Xu, Z., Wang, L., Zhou, J., Yu, Y., Yang, R., Liao, J., & Zhang, L. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3924360 · Cited by 6
Aloriby, M. A., Elkawafi, M., Aldrsy, S., Sweker, M., Elabdeli, H., Elbarghathi, A., Benhasouna, A., El-Awamie, M. W. M., Elsharif, N. A., Alqabbasi, O. S., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1567921 · Cited by 7
“This inhibitory effect is consistent with previous reports emphasizing the potency of olive-derived phenolics, including oleuropein hydroxytyrosol and rutin, in inhibiting both Gram-positive and Gram-negative bacteria (Sudjana et al., 2009; Lee and Lee, 2010; Zori´c and Kosalec, 2022).”
Siga, D. E., Bakchiche, B., Çakır, C., Tuna, K., Öztürk, M., Tounsi, A., Sabour, R., & Ghareeb, M. A. (2025) · South African Journal of Botany · doi:10.1016/j.sajb.2025.06.037 · Cited by 5
Olive Mill Wastewater Bioactive Molecules: Applications in Animal Farming
Imperatore, R., Pagliarulo, C., Orso, G., Cristofaro, G. A. D., Sateriale, D., & Paolucci, M. (2023) · Springer water · doi:10.1007/978-3-031-23449-1_5 · Cited by 5
ERİŞİR, Z., Özçelik, M., Azman, M. A., Mutlu, S. İ., Şimşek, Ü. G., Baykalır, Y., ARSLAN, S., Eroğlu, M., Kocamüftüoğlu, G. O., & ÇİFTÇİ, M. (2020) · Ankara Üniversitesi Veteriner Fakültesi Dergisi · doi:10.33988/auvfd.622127 · Cited by 5
“Phenolic compounds in the olive leaf extract are a free radical scavenger because they break the free radical chain reaction (15, 18).”
BackgroundFactors Affecting Growth and Survival of Salmonella in Onion Extracts and Onion Bulbs
Kiplagat, E., Ramezani, M., Malla, S., Cisneros‐Zevallos, L., Joshi, V., & Castillo, A. (2024) · Foods · doi:10.3390/foods14010001 · Cited by 5
Esmailidehaj, M., Mirhosseini, S.-J., Rezvani, M. E., Rasoulian, B., Mosaddeghmehrjardi, M. H., & Damoon, H. (2012) · Europe PMC (PubMed Central) · Cited by 5
Aşkar, Ş., & Deveboynu, Ş. N. (2019) · Turkish Bulletin of Hygiene and Experimental Biology · doi:10.5505/turkhijyen.2018.53367 · Cited by 5
Ashkanani, M., Farhadi, B., Ghanbarzadeh, E., & Akbari, H. (2020) · Gene Reports · doi:10.1016/j.genrep.2020.100870 · Cited by 5
Kadu, S., Attarde, D. L., Kulkarni, D. A., Shelke, S., & Arsul, V. A. (2021) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2021.00327 · Cited by 5
Coşansu, S., & Kıymetli, Ö. (2021) · International Journal of Agriculture Environment and Food Sciences · doi:10.31015/jaefs.2021.2.14 · Cited by 5
Sarıca, Ş., & Özdemir, D. (2017) · Italian Journal of Animal Science · doi:10.1080/1828051x.2017.1351325 · Cited by 5
Dianat, M., Javidanpour, S., Aliakbari, F., & Sarkaki, A. (2018) · Journal of Research in Medical Sciences · doi:10.4103/jrms.jrms_517_18 · Cited by 5
“Various studies indicated that oleuropein in addition to its antioxidant activity[24] has many useful biological effects on animals and human such as anti‐inflammatory,[25] antidiabetic,[26] anticancer,[27] hypoglycemic, and hypolipidemic.”
Polat, D. Ç., Sarıaltın, S. Y., Çoban, T., & Çoşkun, M. (2019) · Adıyaman üniversitesi fen bilimleri dergisi · doi:10.37094/adyujsci.586664 · Cited by 5
“Not only the fruits but also leaves are used by people for various purposes [5, 13].”
BackgroundInfluentialAnalysis and Evaluation of Hydroxytyrosol in Olive Leaf Extract
Alzweiri, M. H., & Al-Hiari, Y. M. (2013) · Jordan Journal of Pharmaceutical Sciences · doi:10.12816/0001510 · Cited by 5
Djenane, D., Yangüela, J., Derriche, F., Bouarab, L., & Roncalés, P. (2012) · Phytothérapie · doi:10.1007/s10298-011-0665-y · Cited by 6
Rimawi, W. H., & Salim, H. (2016) · Journal of Chemistry and Biochemistry · doi:10.15640/jcb.v4n2a6 · Cited by 5
MAHMMOD, A. (2014) · Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ · doi:10.21608/avmj.2014.166659 · Cited by 5
Antibacterial Activity of the Phenolic Extract of Wild Virgin Olive Oil In Vitro
Bouarroudj, K., Mettouchi, S., Medjkouh, L., Larbat, R., & Tamendjari, A. (2021) · Current Bioactive Compounds · doi:10.2174/1573407218666211230143156 · Cited by 4
Vasarri, M., Degl’Innocenti, D., Albonetti, L., Bilia, A. R., & Bergonzi, M. C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512113 · Cited by 4
“A phytocomplex, that is a whole or partially purified extract of a plant constituent, offers greater efficacy and advantages over a single isolated ingredient, thanks to synergistic interactions [44,45].”
BackgroundVillegas-Aguilar, M. D. C., Cádiz‐Gurrea, M. D. L. L., Sánchez‐Marzo, N., Barrajón‐Catalán, E., Arraéz-Román, D., Fernández‐Ochoa, Á., & Segura‐Carretero, A. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c05325 · Cited by 4
“Both matrices have a common bioactivity, since both species have potent antioxidant, 1,2 anti-inflammatory, 3 antimicrobial, 4 and antitumor properties.”
BackgroundCytotaxonomy of four Floral Variants of Impatiens Balsamina L.
Dash, C. K., Rashid, M. H. A., Sultana, S. S., & Rahman, M. O. (2019) · Journal of Bangladesh Academy of Sciences · doi:10.3329/jbas.v43i1.42227 · Cited by 4
Olive leaf, DNA damage and chelation therapy
Pirković, A., Živković, L., Dekanski, D., Topalović, D., & Spremo‐Potparević, B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819528-4.00021-3 · Cited by 4
Huang, J., Yang, J., Miao, Q., Olajide, T. M., Qian, J., Liu, H., Ou, P., & Liao, X. (2022) · Cereal Chemistry · doi:10.1002/cche.10600 · Cited by 4
EKİCİ, M., Tuncay, H. O., Akalın, E., Bucak, A. Y., & Üresin, A. Y. (2023) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2023.100835 · Cited by 5
Dongre, P., Choudhary, S., Sharma, N., Doifode, C. A., & Sheikh, A. (2024) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2024.100418 · Cited by 4
Progressive approach of phenolic acids toward the advancement of antimicrobial drugs
Aribisala, . O., Aruwa, C. E., & Sabiu, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18538-0.00004-4 · Cited by 4
Marangoni, C., Cichoski, A. J., Barin, J. S., & de Menezes, C. R. (2015) · Brazilian journal of food technology/Brazilian Journal of Food Technology · doi:10.1590/1981-6723.1515 · Cited by 4
de Magalhães, J. C., Nizer, W. S. D. C., Ferraz, A., Moraes, T. D. F. S., Ferreira, F. L., Magalhães, C. L. D. B., Filho, S. A. V., & Duarte, L. (2020) · Journal of Pharmaceutical Negative Results · doi:10.4103/jpnr.jpnr_12_19 · Cited by 4
Safwat, G. M., Kandiel, M. A., Abo-Zaid, O. A., Arafa, M. M., & Mohamed, S. O. (2022) · Advances in Animal and Veterinary Sciences · doi:10.17582/journal.aavs/2022/10.4.731.738 · Cited by 4
Çetinkaya, H., & Kulak, M. (2016) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.4314/ajtcam.v13i2.10 · Cited by 4
Metadata
- Authors
- Lee, O.-H., & Lee, B.-Y.
- Affiliations
- CHA University (KR)
- Corresponding author
- Lee, Ok-Hwan
- Lee, Boo-Yong
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 101
- Issue
- 10
- Pages
- 3751-3754
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2055194600
- Cited by
- 382
- References
- 16
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 21 · 2023: 21 · 2022: 25 · 2021: 38 · 2020: 43 · 2019: 36 · 2018: 29 · 2017: 26 · 2016: 30 · 2015: 23 · 2014: 22 · 2013: 13 · 2012: 21
- FWCI
- 7.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Keywords
- olive leaf extract, Olea europaea, phenolic compounds, antioxidant activity, antimicrobial activity, free radical scavenging, superoxide dismutase-like activity, oleuropein, caffeic acid, agricultural waste valorization, bioactive compounds
- MeSH terms
- Anti-Bacterial Agents, Antioxidants, Microbial Sensitivity Tests, Plant Extracts, Superoxide Dismutase, Plant Leaves, Olea
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
