Two-stage heterotrophic and phototrophic culture strategy for algal biomass and lipid production
Abstract
A two-stage heterotrophic and phototrophic culture strategy for algal biomass and lipid production was studied, wherein high density heterotrophic cultures of Chlorellasorokiniana serve as seed for subsequent phototrophic growth. The data showed growth rate, cell density and productivity of heterotrophic C.sorokiniana were 3.0, 3.3 and 7.4 times higher than phototrophic counterpart, respectively. Hetero- and phototrophic algal seeds had similar biomass/lipid production and fatty acid profile when inoculated into phototrophic culture system. To expand the application, food waste and wastewater were tested as feedstock for heterotrophic growth, and supported cell growth successfully. These results demonstrated the advantages of using heterotrophic algae cells as seeds for open algae culture system. Additionally, high inoculation rate of heterotrophic algal seed can be utilized as an effective method for contamination control. This two-stage heterotrophic phototrophic process is promising to provide a more efficient way for large scale production of algal biomass and biofuels.
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Many algae can be grown in no or low light conditions where they utilise an external carbon source such as acetate or glucose for heterotrophic growth.
“However, many algae can be grown in no or low light conditions where they will utilise an external carbon source such as acetate or glucose for growth in much the same way as animal cells would, and this is referred to as heterotrophic growth [24].”
From Key Targets for Improving Algal Biofuel Production (2021) · cites this paper as [24]
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- Authors
- Zheng, Y., Chi, Z., Lucker, B., & Chen, S.
- Affiliations
- Washington State University (US)
- Corresponding author
- Chen, Shulin
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 103
- Issue
- 1
- Pages
- 484-488
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2089553643
- Cited by
- 148
- References
- 20
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 5 · 2023: 2 · 2022: 12 · 2021: 9 · 2020: 13 · 2019: 13 · 2018: 16 · 2017: 10 · 2016: 14 · 2015: 10 · 2014: 10 · 2013: 18 · 2012: 8
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Boeing
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Keywords
- two-stage culture, heterotrophic culture, Chlorella sorokiniana, algal biomass production, lipid production, fatty acid composition, food waste, wastewater, biofuels, contamination control
- MeSH terms
- Cell Count, Chlamydomonas, Chlorella, Escherichia coli, Fatty Acids, Food, Lipids, Waste Disposal, Fluid, Waste Products, Biomass, Cell Culture Techniques, Phototrophic Processes, Heterotrophic Processes
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