Cited by 116Algal biology and biofuel productionSeaweed-derived Bioactive CompoundsAgricultural and Biological Research

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Production, extraction and stabilization of lutein from microalga Chlorella sorokiniana MB-1

Chen, Chun-Yen, Jesisca, Hsieh, Chienyan, Lee, Duu-Jong, Chang, Chien-Hsiang, Chang, Jo-Shu·2016·Bioresource Technology

DOI 10.1016/j.biortech.2015.10.071

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Abstract

The efficiencies of extraction and preservation of lutein from microalgae are critical for the success of its commercialization. In this study, lutein was produced by Chlorella sorokiniana MB-1 via semi-batch mixotrophic cultivation. The microalgal biomass with a lutein content of 5.21mg/g was pretreated by bead-beating and high pressure cell disruption methods, and the lutein content was harvested by a reduced pressure extraction method. The effect of pretreatment, pressure, solvent type, extraction time and temperature on lutein recovery was investigated. Using high pressure pretreatment followed by extraction with tetrahydrofuran (THF) as solvent resulted in high lutein recovery efficiencies of 87.0% (20min) and 99.5% (40min) at 850mbar and 25°C. In contrast, using ethanol as the solvent, 86.2% lutein recovery was achieved under 450mbar, 35°C and 40min extraction. The extracted lutein was stabilized in olive oil or sunflower oil with half-lives of 53.1 and 63.8days, respectively.

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Authors: Chen, C.-Y., Jesisca, Hsieh, C., Lee, D.-J., Chang, C.-H., & Chang, J.-S.
Affiliations: National Cheng Kung University (TW)
National Kaohsiung Normal University (TW)
National Taiwan University (TW)
Corresponding author: Chang, Jo-Shu
ORCID: Chen, Chun-Yen
Hsieh, Chienyan
Lee, Duu-Jong
Chang, Chien-Hsiang
Chang, Jo-Shu
Venue: Bioresource Technology
Publisher: Elsevier BV
Published: 2016-01
Volume: 200
Pages: 500-505
ISSN: 0960-8524 (ISSN-L)
DOI: 10.1016/j.biortech.2015.10.071
OpenAlex: W2192216707
Cited by: 116
References: 27
Citations by year: 2026: 8 · 2025: 8 · 2024: 12 · 2023: 10 · 2022: 17 · 2021: 14 · 2020: 13 · 2019: 11 · 2018: 7 · 2017: 10 · 2016: 5
FWCI: 2.17
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Bioresource Technology (publishedVersion)
PubMed (publishedVersion)
Funders: Ministry of Education
Ministry of Science and Technology, Taiwan (103-2221-E-006-190-MY3, MOST104-3113-E-006-003)
Topics: Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
Keywords: lutein, Chlorella sorokiniana, microalgae, mixotrophic cultivation, bead beating, lutein extraction, tetrahydrofuran, ethanol extraction, olive oil, sunflower oil, carotenoid recovery
MeSH terms: Olive Oil, Sunflower Oil, Chlorella, Furans, Plant Oils, Pressure, Solvents, Temperature, Lutein, Biomass, Microalgae

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Production, extraction and stabilization of lutein from microalga Chlorella sorokiniana MB-1

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