The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Other studies also show that bacteriocin nisin has a more significant effect on microorganisms such as M. luteus and L. lactis, 17 and also against B. subtilis, S. aureus, MRSA, and VRE18 than hybrids or linear peptides [7]”
From The effect of nisin on the biofilm production, antimicrobial susceptibility and biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa (2022) · cites this paper as [7]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Methods for in vitro evaluating antimicrobial activity: A review
Balouiri, M., Sadiki, M., & Ibnsouda, S. K. (2016) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2015.11.005 · Cited by 8,044
Research works printed but not linked: 58
- Blaskovich, 2017, Polishing the tarnished silver bullet: the quest for new antibiotics, Essays Biochem, 61, 103, 10.1042/EBC20160077 · DOI
- Gilbert, 2010, The 10 × ‘20 initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020, Clin Infect Dis, 50, 1081, 10.1086/652237 · DOI · Paper page
- Moloney, 2016, Trends Pharmacol Sci, 37, 1
- Aguirre, 2016, Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials, Adv Drug Deliv Rev, 106, 223, 10.1016/j.addr.2016.02.004 · DOI · Paper page
- Chatterjee, 2005, Biosynthesis and mode of action of lantibiotics, Chem Rev, 105, 633, 10.1021/cr030105v · DOI · Paper page
- Wilson-Stanford, 2009, Oxidation of lanthionines renders the lantibiotic nisin inactive, Appl Environ Microbiol, 75, 1381, 10.1128/AEM.01864-08 · doi:10.1128/aem.01864-08
- Chan, 1996, Structure-activity relationships in the peptide antibiotic nisin: Role of dehydroalanine 5, Appl Environ Microbiol, 62, 2966, 10.1128/aem.62.8.2966-2969.1996 · doi:10.1128/aem.62.8.2966-2969.1996
- Rollema, 1995, Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering, Appl Environ Microbiol, 61, 2873, 10.1128/aem.61.8.2873-2878.1995 · DOI · Paper page
- Suda, 2010, Effect of bioengineering lacticin 3147 lanthionine bridges on specific activity and resistance to heat and proteases, Chem Biol, 17, 1151, 10.1016/j.chembiol.2010.08.011 · DOI
- Bernbom, 2006, Effects of Lactococcus lactis on composition of intestinal microbiota: role of nisin, Appl Environ Microbiol, 72, 239, 10.1128/AEM.72.1.239-244.2006 · DOI
- Fox, 2013, Antimicrobial peptides stage a comeback, Nat Biotechnol, 31, 379, 10.1038/nbt.2572 · DOI · Paper page
- Delves-Broughton, 1990, Nisin and its application as a food preservative, Int J Dairy Technol, 43, 73, 10.1111/j.1471-0307.1990.tb02449.x · DOI · Paper page
- Zhou, 2014, Mechanisms of nisin resistance in Gram-positive bacteria, Ann Microbiol, 64, 413, 10.1007/s13213-013-0679-9 · DOI
- Breukink, 2006, Lipid II as a target for antibiotics, Nat Rev Drug Discov, 5, 321, 10.1038/nrd2004 · DOI · Paper page
- Ng, 2016, New found hope for antibiotic discovery: lipid II inhibitors, Chem Eur J, 22, 12606, 10.1002/chem.201601315 · DOI
- Hsu, 2004, The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics, Nat Struct Mol Biol, 11, 963, 10.1038/nsmb830 · DOI · Paper page
- Chan, 1996, Structure-activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin, FEBS Lett, 390, 129, 10.1016/0014-5793(96)00638-2 · doi:10.1016/0014-5793(96)00638-2
- Koopmans, 2015, Semisynthetic lipopeptides derived from nisin display antibacterial activity and lipid II binding on par with that of the parent compound, J Am Chem Soc, 137, 9382, 10.1021/jacs.5b04501 · DOI
- Hasper, 2004, Assembly and stability of nisin-lipid II pores, Biochemistry, 43, 11567, 10.1021/bi049476b · DOI · Paper page
- Kuipers, 1996, Protein engineering of lantibiotics, Antoine van Leeuwenhoek, 69, 161, 10.1007/BF00399421 · DOI
- Healy, 2013, Intensive mutagenesis of the nisin hinge leads to the rational design of enhanced derivatives, PLoS ONE, 8, 10.1371/journal.pone.0079563 · DOI
- Zhou, 2015, The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity, Front Microbiol, 6, 11, 10.3389/fmicb.2015.00011 · DOI
- Field, 2010, Studies with bioengineered Nisin peptides highlight the broad-spectrum potency of Nisin V, Microb Biotechnol, 3, 473, 10.1111/j.1751-7915.2010.00184.x · DOI
- Fukase, 1992, Synthetic study on peptide antibiotic nisin. V. Total synthesis of nisin, Bull Chem Soc Jpn, 65, 2227, 10.1246/bcsj.65.2227 · doi:10.1246/bcsj.65.2227
- Bregant, 2005, Orthogonally protected lanthionines: synthesis and use for the solid-phase synthesis of an analogue of nisin ring C, J Org Chem, 70, 2430, 10.1021/jo048222t · doi:10.1021/jo048222t
- Mothia, 2011, Synthesis of peptides containing lanthionine bridges on the solid phase: an analogue of rings D and E of the lantibiotic nisin, Org Lett, 13, 4216, 10.1021/ol201548m · doi:10.1021/ol201548m
- Harmsen, 2014, A conformationally constrained fused tricyclic nisin AB-ring system mimic toward an improved pyrophosphate binder of lipid II, Tetrahedron, 70, 7691, 10.1016/j.tet.2014.06.023 · doi:10.1016/j.tet.2014.06.023
- Ghalit, 2005, Ring-closing alkyne metathesis approach toward the synthesis of alkyne mimics of thioether A-, B-, C-, and DE-ring systems of the lantibiotic nisin Z, Org Lett, 7, 2961, 10.1021/ol0508781 · doi:10.1021/ol0508781
- Slootweg, 2015, Synthesis of nisin AB dicarba analogs using ring-closing metathesis: influence of sp3 versus sp2 hybridization of the α-carbon atom of residues dehydrobutyrine-2 and dehydroalanine-5 on the lipid II binding affinity, Org Biomol Chem, 13, 5997, 10.1039/C5OB00336A · doi:10.1039/c5ob00336a
- Manzor, 2017, Solid-phase peptide synthesis of analogues of the N-terminus A-ring fragment of the lantibiotic nisin: replacements for the dehydroalanine (Dha) residue at position 5 and the first incorporation of a thioamide residue, Tetrahedron Lett, 58, 2959, 10.1016/j.tetlet.2017.06.052 · doi:10.1016/j.tetlet.2017.06.052
- Liu, 2011, Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147, J Am Chem Soc, 133, 14216, 10.1021/ja206017p · doi:10.1021/ja206017p
- Ross, 2010, Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase, J Am Chem Soc, 132, 462, 10.1021/ja9095945 · doi:10.1021/ja9095945
- Tabor, 2011, The challenge of the lantibiotics: synthetic approaches to thioether-bridged peptides, Org Biomol Chem, 9, 7606, 10.1039/c1ob05946g · doi:10.1039/c1ob05946g
- Escano, 2015, Multipronged approach for engineering novel peptide analogues of existing lantibiotics, Expert Opin Drug Discovery, 10, 857, 10.1517/17460441.2015.1049527 · DOI
- Sandiford, 2015, Perspectives on lantibiotic discovery – where have we failed and what improvements are required?, Expert Opin Drug Discovery, 10, 315, 10.1517/17460441.2015.1016496 · DOI
- Tabor, 2014, Recent advances in synthetic analogues of lantibiotics: what can we learn from these?, Bioorg Chem, 55, 39, 10.1016/j.bioorg.2014.04.004 · DOI
- Arnusch, 2008, The vancomycin-nisin (1–12) hybrid restores activity against vancomycin resistant enterococci, Biochemistry, 47, 12661, 10.1021/bi801597b · DOI
- Arnusch, 2012, Enhanced membrane pore formation through high-affinity targeted antimicrobial peptides, PLoS ONE, 7, 10.1371/journal.pone.0039768 · doi:10.1371/journal.pone.0039768
- Slootweg, 2014, Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment, Bioorg Med Chem, 22, 5345, 10.1016/j.bmc.2014.07.046 · DOI
- Zhou, 2016, Potentiating the activity of nisin against Escherichia coli, Front Cell Dev Biol, 4, 7, 10.3389/fcell.2016.00007 · DOI
- Valverde, 2013, 1,2,3-Triazoles as amide bond mimics: triazole scan yields protease-resistant peptidomimetics for tumor targeting, Angew Chem Int Ed, 52, 8957, 10.1002/anie.201303108 · DOI · Paper page
- Souza, 2005, Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista, Peptides, 26, 2157, 10.1016/j.peptides.2005.04.026 · DOI · Paper page
- Cabrera, 2008, Selectivity in the mechanism of action of antimicrobial mastoparan peptide Polybia-MP1, Eur Biophys J, 37, 879, 10.1007/s00249-008-0299-7 · doi:10.1007/s00249-008-0299-7
- Ge, 1999, In vitro antibacterial properties of pexiganan, an analog of magainin, Antimicrob Agents Chemother, 43, 782, 10.1128/AAC.43.4.782 · DOI · Paper page
- Porcelli, 2006, Structures of the dimeric and monomeric variants of magainin antimicrobial peptides (MSI-78 and MSI-594) in micelles and bilayers, determined by NMR, Biochemistry, 45, 5793, 10.1021/bi0601813 · DOI · Paper page
- Hallock, 2003, MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain, Biophys J, 84, 3052, 10.1016/S0006-3495(03)70031-9 · DOI · Paper page
- Simon, 1992, Peptoids: a modular approach to drug discovery, Proc Natl Acad Sci USA, 89, 9367, 10.1073/pnas.89.20.9367 · DOI · Paper page
- Chongsiriwatana, 2008, Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides, Proc Natl Acad Sci USA, 105, 2794, 10.1073/pnas.0708254105 · DOI · Paper page
- Hamley, 2014, PEG-peptide conjugates, Biomacromolecules, 15, 1543, 10.1021/bm500246w · DOI · Paper page
- Slootweg, 2013, Scalable purification of the lantibiotic nisin and isolation of chemical/enzymatic cleavage fragments suitable for semi-synthesis, J Pept Sci, 19, 692, 10.1002/psc.2551 · doi:10.1002/psc.2551
- Slootweg, 2013, Synthesis, antimicrobial activity, and membrane permeabilizing properties of C-terminally modified nisin conjugates accessed by CuAAC, Bioconjugate Chem, 24, 2058, 10.1021/bc400401k · doi:10.1021/bc400401k
- Rink, 1987, Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin, Tetrahedron Lett, 28, 3787, 10.1016/S0040-4039(00)96384-6 · DOI · Paper page
- Patch, 2003, Helical peptoid mimics of magainin-2 amide, J Am Chem Soc, 125, 12092, 10.1021/ja037320d · DOI · Paper page
- Chan, 2004, Polytriazoles as copper(I)-stabilizing ligands in catalysis, Org Lett, 6, 2853, 10.1021/ol0493094 · DOI · Paper page
- Bolt, 2018, Synthesis of antibacterial nisin-peptoid hybrids using click methodology, Molecules, 23, 10.3390/molecules23071566 · doi:10.3390/molecules23071566
- Medeiros-Silva, 2018, High-resolution NMR studies of antibiotics in cellular membranes, Nat Commun, 9, 3963, 10.1038/s41467-018-06314-x · DOI
- Cornish, 1999, Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes, Am J Physiol, 277, E779
- Wiegand, 2008, Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances, Nat Protoc, 3, 163, 10.1038/nprot.2007.521 · DOI · Paper page
Cited by
Gan, B. H., Gaynord, J., Rowe, S. M., Deingruber, T., & Spring, D. R. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00729c · Cited by 511
Ghapanvari, P., Taheri, M., Jalilian, F. A., Dehbashi, S., Dezfuli, A. A. Z., & Arabestani, M. R. (2022) · European Journal of Medical Research · doi:10.1186/s40001-022-00804-x · Cited by 38
Metadata
- Authors
- Mitchell, S. A., Truscott, F., Dickman, R., Ward, J., & Tabor, A. B.
- Venue
- Bioorganic & Medicinal Chemistry
- Publisher
- Elsevier BV
- Published
- 2018-11
- Volume
- 26
- Issue
- 21
- Pages
- 5691-5700
- ISSN
- 0968-0896
- Cited by
- 22
- References
- 1
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- creativecommons.org/licenses/by/4.0/ (vor)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides. https://app.cochat.ai/papers/10.1016/j.bmc.2018.10.015
- The paper
- Mitchell, S. A., Truscott, F., Dickman, R., Ward, J., & Tabor, A. B. (2018). Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides. Bioorganic & Medicinal Chemistry. https://doi.org/10.1016/j.bmc.2018.10.015
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.