The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Photoplethysmography
Abstract
The photoplethysmographic (PPG) waveform, also known as the pulse oximeter waveform, is one of the most commonly displayed clinical waveforms. First described in the 1930s, the technology behind the waveform is simple. The waveform, as displayed on the modern pulse oximeter, is an amplified and highly filtered measurement of light absorption by the local tissue over time. It is optimized by medical device manufacturers to accentuate its pulsatile components. Physiologically, it is the result of a complex, and not well understood, interaction between the cardiovascular, respiratory, and autonomic systems. All modern pulse oximeters extract and display the heart rate and oxygen saturation derived from the PPG measurements at multiple wavelengths. "As is," the PPG is an excellent monitor for cardiac arrhythmia, particularly when used in conjunction with the electrocardiogram (ECG). With slight modifications in the display of the PPG (either to a strip chart recorder or slowed down on the monitor screen), the PPG can be used to measure the ventilator-induced modulations which have been associated with hypovolemia. Research efforts are under way to analyze the PPG using improved digital signal processing methods to develop new physiologic parameters. It is hoped that when these new physiologic parameters are combined with a more modern understanding of cardiovascular physiology (functional hemodynamics) the potential utility of the PPG will be expanded. The clinical researcher's objective is the use of the PPG to guide early goal-directed therapeutic interventions (fluid, vasopressors, and inotropes), in effect to extract from the simple PPG the information and therapeutic guidance that was previously only obtainable from an arterial pressure line and the pulmonary artery catheter.
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“It is reported that the lower-frequency wave manifestation in the total PPG signal can be attributed to the venous vascular system [119].”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [119]
Citations
Cites
Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use
Electrophysiology, T. F. O. T. E. S. O. C. T. N. A. (1996) · Circulation · doi:10.1161/01.cir.93.5.1043 · Cited by 17,159
Non-contact, automated cardiac pulse measurements using video imaging and blind source separation
Poh, M., McDuff, D., & Picard, R. W. (2010) · Optics Express · doi:10.1364/oe.18.010762 · Cited by 1,652
Gan, T. J., Soppitt, A. J., Maroof, M., El-Moalem, H. E., Robertson, K. M., Moretti, E., Dwane, P., & Glass, P. S. A. (2002) · Anesthesiology · doi:10.1097/00000542-200210000-00012 · Cited by 950
Hamilton, M. A., Cecconi, M., & Rhodes, A. (2010) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181eeaae5 · Cited by 897
Changes in Arterial Pressure during Mechanical Ventilation
Michard, F. (2005) · Anesthesiology · doi:10.1097/00000542-200508000-00026 · Cited by 702
Takazawa, K., Tanaka, N., Fujita, M., Matsuoka, O., Saiki, T., Aikawa, M., Tamura, S., & Ibukiyama, C. (1998) · Hypertension · doi:10.1161/01.hyp.32.2.365 · Cited by 589
Cannesson, M. P., Manach, Y. L., Hofer, C. K., Goarin, J., Lehot, J.-J., Vallet, B., & Tavernier, B. (2011) · Anesthesiology · doi:10.1097/aln.0b013e318225b80a · Cited by 549
THE BLOOD SUPPLY OF VARIOUS SKIN AREAS AS ESTIMATED BY THE PHOTOELECTRIC PLETHYSMOGRAPH
Hertzman, A. B. (1938) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1938.124.2.328 · Cited by 460
Photoplethysmography: Beyond the Calculation of Arterial Oxygen Saturation and Heart Rate
Shelley, K. H. (2007) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000269512.82836.c9 · Cited by 450
Functional hemodynamic monitoring.
Pinsky, M. R., & Payen, D. M. (2005) · Critical Care · doi:10.1186/cc3927 · Cited by 369
Research works printed but not linked: 3
- Hertzman, 1937, Observations on the finger volume pulse recorded photoelectrically, Am J Physiol, 119, 334
- August, 1851, Versuch der absorptions-verhaltnisse des cordierites fur rothes licht zu bestimmen, Ann Physik Chem Ger, 84, 37
- Shelley, 2005, The effect of venous pulsation on the forehead pulse oximeter wave form as a possible source of error in SpO2 calculation, Anesth Analg, 100, 743, 10.1213/01.ANE.0000145063.01043.4B · DOI · Paper page
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Natarajan, A., Pantelopoulos, A., Emir-Farinas, H., & Natarajan, P. (2019) · doi:10.1101/772285 · Cited by 4
Metadata
- Authors
- Alian, A. A., & Shelley, K. H.
- Affiliations
- Yale University (US)
- Corresponding author
- Shelley, Kirk H.
- Venue
- Best Practice & Research Clinical Anaesthesiology
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 28
- Issue
- 4
- Pages
- 395-406
- ISSN
- 1521-6896 (ISSN-L)
- 1753-3740
- OpenAlex
- W4245509891
- Cited by
- 289
- References
- 83
- Citations by year
- 2026: 18 · 2025: 45 · 2024: 36 · 2023: 44 · 2022: 37 · 2021: 25 · 2020: 20 · 2019: 21 · 2018: 17 · 2017: 8 · 2016: 7 · 2015: 9
- FWCI
- 4.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Best practice & research. Clinical anaesthesiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- photoplethysmography, pulse oximetry, arrhythmia monitoring, oxygen saturation, heart rate, hypovolemia, early goal-directed therapy, fluid management, vasopressors, inotropic agents
- MeSH terms
- Hemodynamics, Humans, Oximetry, Photoplethysmography, Hypovolemia
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