Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease

Ballweg, Mary Lou

doi:10.1016/j.bpobgyn.2004.01.003

Cited by 210Endometriosis Research and TreatmentEctopic Pregnancy Diagnosis and ManagementGynecological conditions and treatments

Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease

Ballweg, Mary Lou·2004·Best Practice & Research Clinical Obstetrics & Gynaecology

DOI 10.1016/j.bpobgyn.2004.01.003

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Abstract

Looking at endometriosis from the bigger picture -- as a systemic endocrine, immunological, and gastrointestinal disease -- opens the door to broader treatments. The bigger-picture understanding of the disease also makes clear a variety of patterns of presenting symptoms, again clarifying the diagnosis. Data from over 7000 confirmed cases clearly show that delay in diagnosis (the average time to diagnosis is >9 years) is a major problem and that current treatments are far from satisfactory. In conclusion, the impact of endometriosis, a disease that already produces intense symptoms, is worsened by a current lack of understanding of the disease beyond its pelvic definition.

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There is an increase in incidence of early menarche in young girls displaying endometriosis-related symptoms at an earlier age.
“Owing to an increase in incidence of early menarche in young girls displaying endometriosis-related symptoms at an earlier age (12), the need to identify this cohort by means of a reliable diagnostic marker is imperative.”
From Biomarkers in endometriosis: Challenges and opportunities (2017) · cites this paper as [12]

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Major Gaps in Endometriosis Diagnosis, Treatment
Jones, S. B. (2014)

Authors: Ballweg, M. L.
Corresponding author: Ballweg, Mary Lou
Venue: Best Practice & Research Clinical Obstetrics & Gynaecology
Publisher: Elsevier BV
Published: 2004-04
Volume: 18
Issue: 2
Pages: 201-218
ISSN: 1521-6934 (ISSN-L)
DOI: 10.1016/j.bpobgyn.2004.01.003
OpenAlex: W2087989193
Cited by: 210
References: 12
Citations by year: 2026: 10 · 2025: 13 · 2024: 10 · 2023: 16 · 2022: 15 · 2021: 15 · 2020: 11 · 2019: 13 · 2018: 8 · 2017: 7 · 2016: 7 · 2015: 11 · 2014: 14 · 2013: 10 · 2012: 6
FWCI: 4.52
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Best Practice & Research Clinical Obstetrics & Gynaecology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Keywords: endometriosis, age of onset, disease severity, delayed diagnosis, time to diagnosis, immunological aspects, gastrointestinal symptoms, symptom profiles, diagnosis, treatment
MeSH terms: Adolescent, Adult, Diagnostic Errors, Endometriosis, Female, Humans, Hypersensitivity, Middle Aged, Quality of Life, Treatment Outcome, Age of Onset

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Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease

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