The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.
Cognitive-behavioral therapy for hypochondriasis/health anxiety: A meta-analysis of treatment outcome and moderators
Abstract
The present investigation employed meta-analysis to examine the efficacy of cognitive-behavioral therapy (CBT) for hypochondriasis/health anxiety as well as potential moderators that may be associated with outcome. A literature search revealed 15 comparisons among 13 randomized-controlled trials (RCTs) with a total sample size of 1081 participants that met inclusion criteria. Results indicated that CBT outperformed control conditions on primary outcome measures at post-treatment (Hedges's g = 0.95) and at follow-up (Hedges's g = 0.34). CBT also outperformed control conditions on measures of depression at post-treatment (Hedges's g = 0.64) and at follow-up (Hedges's g = 0.35). Moderator analyses revealed that higher pre-treatment severity of hypochondriasis/health anxiety was associated with greater effect sizes at follow-up visits and depression symptom severity was significantly associated with a lower in effect sizes at post-treatment. Although effect size did not vary as a function of blind assessment, smaller effect sizes were observed for CBT vs. treatment as usual control conditions than for CBT vs. waitlist control. A dose response relationship was also observed, such that a greater number of CBT sessions was associated with larger effect sizes at post-treatment. This review indicates that CBT is efficacious in the treatment of hypochondriasis/health anxiety and identifies potential moderators that are associated with outcome. The implications of these findings for further delineating prognostic and prescriptive indicators of CBT for hypochondriasis/health anxiety are discussed.
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In the citing paper
“In clinical practice, OCD is considered as the most resistant anxiety disorder; a finding that is empirically supported by several meta-analyses which show that remission rate of OCD 1 year after conclusion of an evidence-based treatment with a SSRI or a cognitive behavioral approach is about 53% and that treatment effect diminished rapidly after the acute treatment phase [8–10].”
In the citing paper
“In clinical practice, OCD is considered as the most resistant anxiety disorder; a finding that is empirically supported by several meta-analyses which show that remission rate of OCD 1 year after conclusion of an evidence-based treatment with a SSRI or a cognitive behavioral approach is about 53% and that treatment effect diminished rapidly after the acute treatment phase [8–10].”
In the citing paper
“In clinical practice, OCD is considered as the most resistant anxiety disorder; a finding that is empirically supported by several meta-analyses which show that remission rate of OCD 1 year after conclusion of an evidence-based treatment with a SSRI or a cognitive behavioral approach is about 53% and that treatment effect diminished rapidly after the acute treatment phase [8–10].”
In the citing paper
“Cognitive behavioral therapy (CBT) has the greatest evidence base for health anxiety management compared with several control conditions, including treatment as usual, medication, placebo, waitlist, support groups, non-CBT–based psychoeducation, and other psychological interventions [20,21].”
From A Cognitive Behavioral Therapy Chatbot (Otis) for Health Anxiety Management: Mixed Methods Pilot Study (2022) · cites this paper as [21]
In the citing paper
“with most evidence obtained with forms of cognitive behavioural therapy (CBT) but also including stress management, mindfulness and acceptance, and commitment therapy.[10][11][12]”
From Why health anxiety needs to be recognised in hospital practice (2020) · cites this paper as [10]
In the citing paper
“Cognitive behavioural therapy (CBT) is an empirically supported treatment for health anxiety that has demonstrated efficacy in group and individual formats ( Olatunji et al., 2014 )”
From Internet-Based Cognitive Behavioral Therapy Versus Psychoeducation Control for Illness Anxiety Disorder and Somatic Symptom Disorder: A Randomized Controlled Trial (2018) · cites this paper as Olatunji et al., 2014
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Cited by
Sorted by citations
Mental Health Smartphone Apps: Review and Evidence-Based Recommendations for Future Developments
Bakker, D., Kazantzis, N., Rickwood, D., & Rickard, N. (2016) · JMIR Mental Health · doi:10.2196/mental.4984 · Cited by 886
Watson, D., Levin‐Aspenson, H. F., Waszczuk, M. A., Conway, C. C., Dalgleish, T., Dretsch, M. N., Eaton, N. R., Forbes, M. K., Forbush, K. T., Hobbs, K. A., et al. (2022) · World Psychiatry · doi:10.1002/wps.20943 · Cited by 311
Rathbone, A. L., Clarry, L., & Prescott, J. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.8598 · Cited by 158
Newby, J. M., Hobbs, M. J., Mahoney, A. E. J., Wong, S. (., & Andrews, G. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.07.010 · Cited by 148
Health anxiety and hypochondriasis in the light of DSM-5
Bailer, J., Kerstner, T., Witthöft, M., Diener, C., Mier, D. U., & Rist, F. (2015) · Anxiety Stress & Coping · doi:10.1080/10615806.2015.1036243 · Cited by 130
Metadata
- Authors
- Olatunji, B. O., Kauffman, B. Y., Meltzer, S., Davis, M. L., Smits, J. A. J., & Powers, M. B.
- Affiliations
- Vanderbilt University (US)
- The University of Texas at Austin (US)
- Corresponding author
- Olatunji, Bunmi O.
- Venue
- Behaviour Research and Therapy
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 58
- Pages
- 65-74
- ISSN
- 0005-7967 (ISSN-L)
- OpenAlex
- W2078070910
- Cited by
- 167
- References
- 78
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 15 · 2023: 8 · 2022: 12 · 2021: 19 · 2020: 14 · 2019: 17 · 2018: 12 · 2017: 25 · 2016: 14 · 2015: 17 · 2014: 2
- FWCI
- 2.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behaviour Research and Therapy (publishedVersion)
- PubMed (publishedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- cognitive behavioral therapy, health anxiety, treatment outcomes, treatment moderators, depression, symptom severity, dose-response relationship, waitlist control, usual care
- MeSH terms
- Adult, Aged, Depression, Humans, Hypochondriasis, Middle Aged, Models, Psychological, Cognitive Behavioral Therapy, Treatment Outcome
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