HDAC family: What are the cancer relevant targets?
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Items 401–500 of 1,000
- Novel N -hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicityTran Lan Huong, Do Thi Mai Dung, Nguyen-Van Huan, Le-Van Cuong, Hai Pham‐The, Huong Le‐Thi‐Thu, Jisung Kim, Yong-Guk Kim, Sang‐Bae Han, Nguyen‐Hai Nam · 2017 · Bioorganic Chemistry
- The Antiangiogenesis Role of Histone Deacetylase Inhibitors: Their Potential Application to Tumor Therapy and Tissue RepairBin Deng, Qing Luo, Alexander Halim, Qiuping Liu, Bingyu Zhang, Guanbin Song · 2019 · DNA and Cell Biology
- The Role of Epigenetics in the Chronic Sinusitis with Nasal PolypTiancong Liu, Yang Sun, Weiliang Bai · 2020 · Current Allergy and Asthma Reports
- Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID-19 patientsВ. А. Иванисенко, Evgeniy V. Gaisler, Nikita V. Basov, Artem D. Rogachev, Sergey V. Cheresiz, Timofey Ivanisenko, Деменков Павел Сергеевич, E. L. Mishchenko, Olga P. Khripko, Yu. I. Khripko et al. · 2022 · Scientific Reports
- Progress of small molecules for targeted protein degradation: PROTACs and other technologiesHongyi Zhao, Minhang Xin, San‐Qi Zhang · 2023 · Drug Development Research
- Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4Kim · 2009 · International Journal of Oncology
- Novel hybrids from N-hydroxyarylamide and indole ring through click chemistry as histone deacetylase inhibitors with potent antitumor activitiesMao Cai, Jie Hu, Jilai Tian, Huang Yan, Chenguo Zheng, Wanle Hu · 2015 · Chinese Chemical Letters
- Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitorsKôichi Narita, 松原圭介, Jun Itoh, Yui Akiyama, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2016 · European Journal of Medicinal Chemistry
- HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axisBaoyu Duan, Dan Ye, Songcheng Zhu, Wenwen Jia, Chenqi Lu, Guiying Wang, Xudong Guo, Yangyang Yu, Chuanyue Wu, Jiuhong Kang · 2017 · Oncotarget
- Role of epigenetic regulation in glaucomaLemeng Feng, Chao Wang, Cheng Zhang, Wulong Zhang, Weitao Song · 2023 · Biomedicine & Pharmacotherapy
- HDAC Inhibition Sensitize Hepatocellular Carcinoma to Lenvatinib via Suppressing AKT ActivationShuai Yan, Lu Chen, Hao Zhuang, Hui Yang, Yinmo Yang, Ning Zhang, Rong Liu · 2024 · International Journal of Biological Sciences
- Combinations of HDAC Inhibitor and PPAR Agonist Induce Ferroptosis of Leukemic Stem Cell–like Cells in Acute Myeloid LeukemiaHui Zhou, Dongmei Qin, Chendi Xie, Jie Zhou, Shuman Jia, Ziwei Zhou, Yi Qiu, Bing Xu, Jie Zha · 2024 · Clinical Cancer Research
- Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-PathogenesisAmir Zeb, Chanin Park, Shailima DV Rampogu, Minky Son, Gihwan Lee, Keun Woo Lee · 2018 · ACS Chemical Neuroscience
- Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cellsBin Shi, Fangfang Xu, Caiping Xiang, Ru Jia, Chun-Hong Yan, Se-Qing Ma, Ning Wang, An-Jiao Wang, Ping Fan · 2020 · Oncology Letters
- Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, PanobinostatLukman Olalekan Afolabi, Jiacheng Bi, Xuguang Li, Adeleye Oluwatosin Adeshakin, Funmilayo Oladunni Adeshakin, Haisi Wu, Dehong Yan, Liang Chen, Xiaochun Wan · 2021 · Frontiers in Immunology
- HDAC expression and activity is upregulated in diseased lupus-prone miceNicole L. Regna, Miranda D. Vieson, Alexander M. Gojmerac, Xin Luo, David L. Caudell, Christopher M. Reilly · 2015 · International Immunopharmacology
- Targeting of histone deacetylases in brain tumorsJonas Ecker, Olaf Witt, Till Milde · 2013 · CNS Oncology
- Structural insight into the separate roles of inositol tetraphosphate and deacetylase‐activating domain in activation of histone deacetylase 3Mehrnoosh Arrar, Rigney E. Turnham, Levi Pierce, César Augusto F. de Oliveira, James Andrew McCammon · 2012 · Protein Science
- HDAC6 and Ovarian CancerJoshua Haakenson, Xiaohong Mary Zhang · 2013 · International Journal of Molecular Sciences
- Epigenetic Regulation of Phosphatidylinositol 3,4,5-Triphosphate-dependent Rac Exchanger 1 Gene Expression in Prostate Cancer CellsChuu‐Yun A. Wong, Hada Wuriyanghan, Yan Xie, Ming‐Fong Lin, Peter W. Abel, Yaping Tu · 2011 · Journal of Biological Chemistry
- Platinum(IV) prodrugs multiply targeting genomic DNA, histone deacetylases and PARP-1Zichen Xu, Weiwei Hu, Zhimei Wang, Shaohua Gou · 2017 · European Journal of Medicinal Chemistry
- A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblastomaAndres F. Espinoza, Roma H. Patel, Kalyani R. Patel, Andrew Badachhape, Richard S. Whitlock, Rohit Kumar Srivastava, Saiabhiroop R. Govindu, Ashley T. Duong, Abhishek Kona, Pavan Kureti et al. · 2024 · Journal of Hepatology
- Potential non-oncological applications of histone deacetylase inhibitors.Katherine Ververis, Tom C. Karagiannis · 2011 · Europe PMC (PubMed Central)
- Upregulation of NKG2D ligands in acute lymphoblastic leukemia and non-Hodgkin lymphoma cells by romidepsin and enhanced in vitro and in vivo natural killer cell cytotoxicityPrakash Satwani, Sejal Bavishi, Aniket Saha, Frances Zhao, Janet S Ayello, Carmella van de Ven, Yaya Chu, Mitchell Stuart Cairo · 2014 · Cytotherapy
- New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cellsFabien Gueugnon, Pierre‐François Cartron, Cédric Charrier, Philippe Bertrand, Jean‐François Fonteneau, Marc Grégoire, Christophe Blanquart · 2014 · Oncotarget
- Zyflamend, a Combination of Herbal Extracts, Attenuates Tumor Growth in Murine Xenograft Models of Prostate CancerE.-Chu Huang, Michael F. McEntee, Jay Whelan · 2012 · Nutrition and Cancer
- A histone deacetylase inhibitor improves hypothyroidism caused by a TR 1 mutantDong‐Wook Kim, Ji Won Park, Mark C. Willingham, Sheue-yann Cheng · 2013 · Human Molecular Genetics
- Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancerEmre Gerçeker, Sedat Boyacıoğlu, Elmas Kasap, Ahmed Ramiz Baykan, Hakan Yüceyar, HATICE YILDIRIM, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz · 2015 · Oncology Reports
- Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder CancerDavid R. Li, Hanwei Zhang, Elizabeth M. Peek, Song Wang, Lin Du, Gang Li, Arnold I. Chin · 2015 · The Journal of Urology
- Panobinostat for the treatment of acute myelogenous leukemiaFortunato Morabito, Maria Teresa Voso, Stefan Hohaus, Massimo Gentile, Ernesto Vigna, Anna Grazia Recchia, Lorenzo Iovino, E. Benedetti, Francesco Lo‐Coco, Sara Galimberti · 2016 · Expert Opinion on Investigational Drugs
- Indole: A Privileged Heterocyclic Moiety in the Management of CancerReyaz Hassan Mir, Roohi Mohi-ud-din, Taha Umair Wani, Mohammad Ovais Dar, Abdul Jalil Shah, Bashir Ahmad Lone, Pooja A. Chawla, Mubashir Hussain Masoodi · 2021 · Current Organic Chemistry
- Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.Lingling Chang, Mei‐Mei Kau, Wan-Song Alfred Wun, Low-Tone Ho, Paulus S. Wang · 2002 · PubMed
- Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer CellsHoffmann, Michèle J., Meneceur, Sarah, Hommel, Katrin, Schulz, Wolfgang A., Niegisch, Günter · 2021 · Genes
- ROS-responsive thioketal nanoparticles delivering system for targeted ulcerative colitis therapy with potent HDAC6 inhibitor, tubastatin APrabhat Shrestha, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jee‐Heon Jeong, Simmyung Yook · 2024 · European Journal of Pharmaceutical Sciences
- Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea‐Based HDAC InhibitorsFinn Kristian Hansen, Tina S. Skinner‐Adams, Sandra Duffy, Linda Marek, Subathdrage D.M. Sumanadasa, Krystina Kuna, Jana Held, Vicky M. Avery, Katherine T. Andrews, Thomas Kurz · 2014 · ChemMedChem
- Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosisMingming Zhang, Yida Pan, Dehua Tang, Robert Gregory Dorfman, Lei Xu, Qian Zhou, Lixing Zhou, Yuming Wang, Li Yang, Yuyao Yin et al. · 2019 · Cell Communication and Signaling
- Modulation of serine/threonine-protein phosphatase 1 (PP1) complexes: A promising approach in cancer treatmentBárbara Matos, John Howl, Cármen Jerónimo, Margarida Fardilha · 2021 · Drug Discovery Today
- Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancerSophia N. Ononye, Michael van Heyst, Eric M Falcone, A. Anderson, D. Wright · 2012 · Pharmaceutical Patent Analyst
- Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosisSong Li, Baolu Wang, Yan Xu, Junjie Zhang · 2011 · Molecular Cancer
- TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasmsJohn K. Simmons, Jyoti D. Patel, Aleksandra M. Michalowski, Shuling Zhang, Bih‐Rong Wei, Patrick Sullivan, Ben Gamache, Kenneth M. Felsenstein, Walter Michael Kuehl, Richard J. Simpson et al. · 2013 · Molecular Oncology
- Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytesMaxim V. Kozlov, Alla A. Kleymenova, Konstantin A. Konduktorov, Alsu Z. Malikova, Sergey N. Kochetkov · 2014 · Biochemistry (Moscow)
- Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR studyJiachen Wen, Qun Niu, Jiang Liu, Yu J. Bao, Jinyu Yang, Shenglin Luan, Yinbo Fan, Dan Liu, Linxiang Zhao · 2015 · Bioorganic & Medicinal Chemistry Letters
- AKT activation controls cell survival in response to HDAC6 inhibitionMaciej A. Kaliszczak, Sebastian Trousil, T Ali, Eric Ofori Aboagye · 2016 · Cell Death and Disease
- Strategies that regulate LSD1 for novel therapeuticsMeng Li, Mengge Dai, Bing Cheng, Shaotong Li, Enhui Guo, Junwei Fu, Ting Ma, Bin Yu · 2024 · Acta Pharmaceutica Sinica B
- Determination of CK2 Specificity and Substrates by Proteome-Derived Peptide LibrariesChunli Wang, Mingliang Ye, Yangyang Bian, Fangjie Liu, Kai Cheng, Mingming Dong, Jing Dong, Hanfa Zou · 2013 · Journal of Proteome Research
- Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future ProspectsDaniel Alencar Rodrigues, Pedro de Sena Murteira Pinheiro, Carlos Alberto Manssour Fraga · 2020 · ChemMedChem
- Histone Deacetylase‐Triggered Self‐Immolative Peptide‐Cytotoxins for Cancer‐Selective Drug DeliveryHaoyu Bai, Huifang Wang, Zhuha Zhou, Ying Piao, Xiangrui Liu, Jianbin Tang, Xian Shen, Youqing Shen, Zhuxian Zhou · 2023 · Advanced Functional Materials
- Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222Stefania Terracciano, Simone Di Micco, Giuseppe Bifulco, Paola Gallinari, Raffaele Riccio, Ines Bruno · 2010 · Bioorganic & Medicinal Chemistry
- Understanding Histone Deacetylases in the Cancer Development and Treatment: An Epigenetic Perspective of Cancer ChemotherapyMudassier Ahmad, Abid Hamid, Aashiq Hussain, Rabiya Majeed, Yasrib Qurishi, Javeed Ahmad Bhat, Rauf Ahmad Najar, Asif Khurshid Qazi, Mohammad Afzal Zargar, Shashank Kumar Singh et al. · 2012 · DNA and Cell Biology
- Energy-optimised pharmacophore approach to identify potential hotspots during inhibition of Class II HDAC isoformsShabir Ahmad Ganai, Karthi Shanmugam, Vijayalakshmi Mahadevan · 2014 · Journal of Biomolecular Structure and Dynamics
- A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies.Wei-Jan Huang, Yen-An Tang, Mei-Yu Chen, Ying-Jan Wang, F. Hu, Tseng-Wei Wang, Shi-Wei Chao, Hui-Wen Chiu, Ya-Ling Yeh, Hsin-Yi Chang et al. · 2014 · Cancer Letters
- Histone Deacetylases and Their Role in AsthmaSimon G. Royce, Tom C. Karagiannis · 2012 · Journal of Asthma
- Design, synthesis and primary activity assay of tripeptidomimetics as histone deacetylase inhibitors with linear linker and branched cap groupYingjie Zhang, Jinhong Feng, Yuping Jia, Yingying Xu, Chunxi Liu, Hao Fang, Wenfang Xu · 2011 · European Journal of Medicinal Chemistry
- A Chimeric SERM–Histone Deacetylase Inhibitor Approach to Breast Cancer TherapyHitisha Patel, Marton I. Siklos, Hazem Abdelkarim, Emma L. Mendonca, Aditya Sudheer Vaidya, Pavel A. Petukhov, Gregory R. J. Thatcher · 2013 · ChemMedChem
- Design, synthesis and biological evaluation of novel hydroxamic acids bearing artemisinin skeletonVũ Thị Thu Hà, Vu Tuan Kien, Le Huy Binh, Vũ Đình Tiến, Nguyen Thi Thuy My, Nguyen‐Hai Nam, Michel Baltas, Hyunggu Hahn, Byung Woo Han, Đỗ Thị Thảo et al. · 2016 · Bioorganic Chemistry
- Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in hepatocellular carcinomaSrinivas Chatla, V. Swathi, Chiliveru Priyanka, Tangutur Anjana Devi, B. V. Subba Reddy, Mekala Janaki Ramaiah, Utpal Bhadra, Manika Pal Bhadra · 2016 · APOPTOSIS
- HDAC8 regulates neural differentiation through embryoid body formation in P19 cellsSyouichi Katayama, Atsushi Morii, Juliet O. Makanga, Takayoshi Suzuki, Naoki Miyata, Tetsuya Inazu · 2018 · Biochemical and Biophysical Research Communications
- Total synthesis of bicyclic depsipeptides spiruchostatins C and D and investigation of their histone deacetylase inhibitory and antiproliferative activitiesKôichi Narita, Yurie Fukui, Yui Sano, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2012 · European Journal of Medicinal Chemistry
- Novel molecular targets in hepatocellular carcinomaAriel Ka-Man Chow, Simon Wing-Lung Yau, Lui Ng · 2020 · World Journal of Clinical Oncology
- New Role for Histone Deacetylase 9 in Atherosclerosis and InflammationJonathan D. Smith · 2014 · Arteriosclerosis Thrombosis and Vascular Biology
- Acetyl-CoA: an interplay between metabolism and epigenetics in cancerHao, Yang, Yi, Qin, XiaoWu, Xu, WeiBo, Chen, GuangChen, Zu, XueMin, Chen · 2022 · Frontiers in Molecular Medicine
- Tetrahydro-β-carboline derivatives as potent histone deacetylase 6 inhibitors with broad-spectrum antiproliferative activityXin Chen, Jiayun Wang, Peng Zhao, Baiyun Dang, Ting Liang, Raphael R. Steimbach, Aubry K. Miller, Jia Liu, Xin Wang, Tongtong Zhang et al. · 2023 · European Journal of Medicinal Chemistry
- Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic miceAhmet Ozer, Cengiz Zubeyir Altuntas, Fuat Bicer, Kenan İzgi, Scott J. Hultgren, Guiming Liu, Firouz Daneshgari · 2015 · Pathogens and Disease
- Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approachQingdi Quentin Li, Jian-Jiang Hao, Zheng Zhang, Iawen Hsu, Yi Liu, Zhen Tao, Keidren Lewi, Adam R. Metwalli, Piyush Kumar Agarwal · 2016 · International Journal of Oncology
- Using Zebrafish to Study Kidney Development and DiseaseStephanie Jerman, Zhaoxia Sun · 2017 · Current topics in developmental biology/Current Topics in Developmental Biology
- Synthesis of N′-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV)Maxim V. Kozlov, Konstantin A. Konduktorov, Anastasia S. Shcherbakova, Sergey N. Kochetkov · 2019 · Bioorganic & Medicinal Chemistry Letters
- Molecular targets in cancer prevention by 4-(methylthio)butyl isothiocyanate - A comprehensive reviewDavinder Pal Singh, Rohit Arora, Astha Bhatia, H.B. Singh, Balbir Singh, Saroj Arora · 2019 · Life Sciences
- The metabolic addiction of cancer stem cellsOm Saswat Sahoo, Karthikeyan Pethusamy, Tryambak Pratap Srivastava, Joyeeta Talukdar, Mohammed Saeed Alqahtani, Mohamed Abd Elhamid Abbas, Ruby Dhar, Subhradip Karmakar · 2022 · Frontiers in Oncology
- Histone acetyltransferases and histone deacetyl transferases play crucial role during oogenesis and early embryo developmentNazlıcan Bozdemir, Fatma Uysal · 2023 · genesis
- HDAC11: A novel target for improved cancer therapyYan Liu, Xuechao Tong, Weina Hu, Da Chen · 2023 · Biomedicine & Pharmacotherapy
- Design, synthesis and antiproliferative activities of novel benzamides derivatives as HDAC inhibitorsYanyang Li, Yongzhen Wang, Ning Xie, Ming Xu, Pengyu Qian, Yanjin Zhao, Shuxin Li · 2015 · European Journal of Medicinal Chemistry
- Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl RingFrédérik Oger, Aurélien Lecorgne, Elisa Sala, Vanessa Nardese, Florence Demay, Soizic Chevance, Danielle C. Desravines, Nataliia Aleksandrova, Rémy Le Guével, Simone Lorenzi et al. · 2010 · Journal of Medicinal Chemistry
- Epigenetic marks in melanomaHunter W. Richards, Estela E. Medrano · 2008 · Pigment Cell & Melanoma Research
- Identification of Histone Deacetylase 1 Protein Complexes in Liver Cancer CellsMuhammad Farooq, Wael Nabil Hozzein, Elsayed A. Elsayed, Nael Abu Taha, Mohammad A.M. Wadaan · 2013 · Asian Pacific Journal of Cancer Prevention
- Design, synthesis and biological evaluation of 2-amino-N-(2-aminophenyl)thiazole-5-carboxamide derivatives as novel Bcr-Abl and histone deacetylase dual inhibitorsXin Chen, Shuang Zhao, Yichao Wu, Yadong Chen, Tao Lu, Yong Zhu · 2016 · RSC Advances
- Methods for the expression, purification, and crystallization of histone deacetylase 6–inhibitor complexesJ.D. Osko, David W. Christianson · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
- OIP5‑AS1 modulates epigenetic regulator HDAC7 to enhance non‑small cell lung cancer metastasis via miR‑140‑5pJiazhuan Mei, Guiju Liu, Wenhui Wang, Peng Xiao, Dan Yang, Hua Bai, Ruijun Li · 2020 · Oncology Letters
- Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent FragmentsLászló Petri, Péter Ábrányi‐Balogh, Tı́mea Imre, Gyula Pálfy, András Perczel, Damijan Knez, Martina Hrast, Martina Gobec, Izidor Sosič, Kinga Nyíri et al. · 2020 · ChemBioChem
- HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCsJianping Zhang, Zhi-Xue Yang, Feng Zhang, Ya-Wen Fu, Xinyue Dai, Wei Wen, Beldon Zhang, Hannah Choi, Wanqiu Chen, Meredith Brown et al. · 2021 · Science China Life Sciences
- Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancerEnerlyn Lozada, Zdeněk Andrysík, Moying Yin, Nicholas Redilla, Kathryn Rice, Peter J. Stambrook · 2016 · Oncotarget
- Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding GroupsGustavo Salgado Pires, Heber Victor Tolomeu, Daniel Alencar Rodrigues, Lı́dia Moreira Lima, Carlos Alberto Manssour Fraga, Pedro de Sena Murteira Pinheiro · 2025 · Pharmaceuticals
- Selective histone deacetylase 6 inhibition prolongs survival in a lethal two-hit modelXin Min Cheng, Zhengcai Liu, Baoling Liu, Ting Zhao, Yongqing Li, Hasan Badre Alam · 2015 · Journal of Surgical Research
- Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistanceShabir Ahmad Ganai · 2016 · Pharmaceutical Biology
- RETRACTED ARTICLE: Fluoxetine induces apoptosis through endoplasmic reticulum stress via mitogen-activated protein kinase activation and histone hyperacetylation in SK-N-BE(2)-M17 human neuroblastoma cellsJi Hyun Choi, Yeon Ju Jeong, Ah-Ran Yu, Kyung‐Sik Yoon, Wonchae Choe, Joohun Ha, Sung Soo Kim, Eui‐Ju Yeo, Insug Kang · 2017 · APOPTOSIS · Retracted
- LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cellsLi Li, Fengyang Li, Xiuhong Hu, Zengshuai Wu, Wenbo Ren, Tingting Wang, Zhengchao Ji, Na Li, Jingmin Gu, Changjiang Sun et al. · 2022 · BMC Cancer
- A Reactivity‐Tunable Self‐Immolative Design Enables Histone Deacetylase‐Targeted Imaging and Prodrug ActivationFeng Liu, Xu Ding, Xiaobo Xu, Fenglin Wang, Xia Chu, Jian‐Hui Jiang · 2022 · Angewandte Chemie International Edition
- Three single nucleotide variants of the HDAC gene are associated with type 2 diabetes mellitus in a Chinese population: A community-based case–control studyZhuanping Zeng, Rifang Liao, Zhenjiang Yao, Weiping Zhou, Ping Ye, Xueyan Zheng, Xing Li, Yanhui Huang, Sidong Chen, Qing Chen · 2013 · Gene
- Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibitionMaciej Purwin, J. Hernández-Toribio, Claire Coderch, Rostyslav R. Panchuk, Nadia R. Skorokhyd, Kamila Filipiak, Beatriz de Pascual‐Teresa, Ana Ramos · 2016 · RSC Advances
- A comparative study based on docking and molecular dynamics simulations over HDAC-tubulin dual inhibitorsMalihe Hassanzadeh, Kowsar Bagherzadeh, Massoud Amanlou · 2016 · Journal of Molecular Graphics and Modelling
- A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancerJiunn-Min Shieh, Yen-An Tang, Fu-Han Hu, Wei‐Jan Huang, Ying-Jan Wang, Jayu Jen, Shengyou Liao, Ying-Hung Lu, Ya-Ling Yeh, Tseng-Wei Wang et al. · 2017 · International Journal of Cancer
- Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motifJinyu Yang, Gaoliang Cheng, Qihao Xu, Shenglin Luan, Shuxiang Wang, Dan Liu, Linxiang Zhao · 2017 · Bioorganic & Medicinal Chemistry
- Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stressChung-Che Wu, Pin-Tse Lee, Tzu‐Jen Kao, Szu‐Yi Chou, Ruei-Yuan Su, Yi‐Chao Lee, Shiu-Hwa Yeh, Jing‐Ping Liou, Tsung‐I Hsu, Tsung‐Ping Su et al. · 2018 · Redox Biology
- Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cellsYodita Asfaha, Christian Schrenk, Leandro A. Alves Avelar, Friedrich Lange, Chenyin Wang, Jan Josef Bandolik, Alexandra Hamacher, Matthias Ulrich Kassack, Thomas Kurz · 2019 · Bioorganic & Medicinal Chemistry
- Development and validation of a sensitive HPLC–MS/MS method for determination of chidamide (epidaza), a new benzamide class of selective histone deacetylase inhibitor, in human plasma and its clinical applicationRuolan Gu, Taoyun Liu, Xiaoxia Zhu, Hui Kong Gan, Zhuona Wu, Jian Li, Ying Zheng, Guifang Dou, Zhiyun Meng · 2015 · Journal of Chromatography B
- HDAC6 serves as a biomarker for the prognosis of patients with renal cell carcinomaZijian Zhang, Yanwei Cao, Weiming Zhao, Lei Guo, Wanpeng Liu · 2017 · Cancer Biomarkers
- Recent advances in dual PROTACs degrader strategies for disease treatmentJianyu Liu, Yanzhuo Liu, Jiao Tang, Qianyuan Gong, Guoyi Yan, Hengrui Fan, Xueping Zhang, Chunlan Pu · 2024 · European Journal of Medicinal Chemistry
- Lactate metabolism and lactylation in breast cancer: mechanisms and implicationsYifan Qiao, Yijia Liu, Ran Ran, Yan Zhou, J Y Gong, Lijuan Liu, Yusi Zhang, Hui Wang, Yuan Fan, Yihan Fan et al. · 2025 · Cancer and Metastasis Reviews
- Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumorsManuraj Pandey, Sarwat Sultana, Krishna Prakash Gupta · 2013 · Experimental and Molecular Pathology
- AR-42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibitionMingming Zhang, Yida Pan, Robert G. Dorfman, Zhaogui Chen, Fuchen Liu, Qian Zhou, Shan Hong Huang, Jun Zhang, Dongqin Yang, Jie Liu · 2016 · Oncotarget
- Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agentsDuong Tien Anh, Hai Pham‐The, Do Thi Mai Dung, Phan Thị Phương Dung, Huong Le‐Thi‐Thu, Eun Jae Park, Hye Won Jun, Jong Soon Kang, Joo‐Hee Kwon, Trương Thanh Tùng et al. · 2020 · Bioorganic & Medicinal Chemistry Letters