HDAC family: What are the cancer relevant targets?

Cited by (1,000)

Items 401–500 of 1,000

  1. Novel N -hydroxybenzamides incorporating 2-oxoindoline with unexpected potent histone deacetylase inhibitory effects and antitumor cytotoxicity
    Tran Lan Huong, Do Thi Mai Dung, Nguyen-Van Huan, Le-Van Cuong, Hai Pham‐The, Huong Le‐Thi‐Thu, Jisung Kim, Yong-Guk Kim, Sang‐Bae Han, Nguyen‐Hai Nam · 2017 · Bioorganic Chemistry
  2. The Antiangiogenesis Role of Histone Deacetylase Inhibitors: Their Potential Application to Tumor Therapy and Tissue Repair
    Bin Deng, Qing Luo, Alexander Halim, Qiuping Liu, Bingyu Zhang, Guanbin Song · 2019 · DNA and Cell Biology
  3. The Role of Epigenetics in the Chronic Sinusitis with Nasal Polyp
    Tiancong Liu, Yang Sun, Weiliang Bai · 2020 · Current Allergy and Asthma Reports
  4. Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID-19 patients
    В. А. Иванисенко, Evgeniy V. Gaisler, Nikita V. Basov, Artem D. Rogachev, Sergey V. Cheresiz, Timofey Ivanisenko, Деменков Павел Сергеевич, E. L. Mishchenko, Olga P. Khripko, Yu. I. Khripko et al. · 2022 · Scientific Reports
  5. Progress of small molecules for targeted protein degradation: PROTACs and other technologies
    Hongyi Zhao, Minhang Xin, San‐Qi Zhang · 2023 · Drug Development Research
  6. Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4
    Kim · 2009 · International Journal of Oncology
  7. Novel hybrids from N-hydroxyarylamide and indole ring through click chemistry as histone deacetylase inhibitors with potent antitumor activities
    Mao Cai, Jie Hu, Jilai Tian, Huang Yan, Chenguo Zheng, Wanle Hu · 2015 · Chinese Chemical Letters
  8. Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors
    Kôichi Narita, 松原圭介, Jun Itoh, Yui Akiyama, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2016 · European Journal of Medicinal Chemistry
  9. HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axis
    Baoyu Duan, Dan Ye, Songcheng Zhu, Wenwen Jia, Chenqi Lu, Guiying Wang, Xudong Guo, Yangyang Yu, Chuanyue Wu, Jiuhong Kang · 2017 · Oncotarget
  10. Role of epigenetic regulation in glaucoma
    Lemeng Feng, Chao Wang, Cheng Zhang, Wulong Zhang, Weitao Song · 2023 · Biomedicine & Pharmacotherapy
  11. HDAC Inhibition Sensitize Hepatocellular Carcinoma to Lenvatinib via Suppressing AKT Activation
    Shuai Yan, Lu Chen, Hao Zhuang, Hui Yang, Yinmo Yang, Ning Zhang, Rong Liu · 2024 · International Journal of Biological Sciences
  12. Combinations of HDAC Inhibitor and PPAR Agonist Induce Ferroptosis of Leukemic Stem Cell–like Cells in Acute Myeloid Leukemia
    Hui Zhou, Dongmei Qin, Chendi Xie, Jie Zhou, Shuman Jia, Ziwei Zhou, Yi Qiu, Bing Xu, Jie Zha · 2024 · Clinical Cancer Research
  13. Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-Pathogenesis
    Amir Zeb, Chanin Park, Shailima DV Rampogu, Minky Son, Gihwan Lee, Keun Woo Lee · 2018 · ACS Chemical Neuroscience
  14. Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells
    Bin Shi, Fangfang Xu, Caiping Xiang, Ru Jia, Chun-Hong Yan, Se-Qing Ma, Ning Wang, An-Jiao Wang, Ping Fan · 2020 · Oncology Letters
  15. Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat
    Lukman Olalekan Afolabi, Jiacheng Bi, Xuguang Li, Adeleye Oluwatosin Adeshakin, Funmilayo Oladunni Adeshakin, Haisi Wu, Dehong Yan, Liang Chen, Xiaochun Wan · 2021 · Frontiers in Immunology
  16. HDAC expression and activity is upregulated in diseased lupus-prone mice
    Nicole L. Regna, Miranda D. Vieson, Alexander M. Gojmerac, Xin Luo, David L. Caudell, Christopher M. Reilly · 2015 · International Immunopharmacology
  17. Targeting of histone deacetylases in brain tumors
    Jonas Ecker, Olaf Witt, Till Milde · 2013 · CNS Oncology
  18. Structural insight into the separate roles of inositol tetraphosphate and deacetylase‐activating domain in activation of histone deacetylase 3
    Mehrnoosh Arrar, Rigney E. Turnham, Levi Pierce, César Augusto F. de Oliveira, James Andrew McCammon · 2012 · Protein Science
  19. HDAC6 and Ovarian Cancer
    Joshua Haakenson, Xiaohong Mary Zhang · 2013 · International Journal of Molecular Sciences
  20. Epigenetic Regulation of Phosphatidylinositol 3,4,5-Triphosphate-dependent Rac Exchanger 1 Gene Expression in Prostate Cancer Cells
    Chuu‐Yun A. Wong, Hada Wuriyanghan, Yan Xie, Ming‐Fong Lin, Peter W. Abel, Yaping Tu · 2011 · Journal of Biological Chemistry
  21. Platinum(IV) prodrugs multiply targeting genomic DNA, histone deacetylases and PARP-1
    Zichen Xu, Weiwei Hu, Zhimei Wang, Shaohua Gou · 2017 · European Journal of Medicinal Chemistry
  22. A novel treatment strategy utilizing panobinostat for high-risk and treatment-refractory hepatoblastoma
    Andres F. Espinoza, Roma H. Patel, Kalyani R. Patel, Andrew Badachhape, Richard S. Whitlock, Rohit Kumar Srivastava, Saiabhiroop R. Govindu, Ashley T. Duong, Abhishek Kona, Pavan Kureti et al. · 2024 · Journal of Hepatology
  23. Potential non-oncological applications of histone deacetylase inhibitors.
    Katherine Ververis, Tom C. Karagiannis · 2011 · Europe PMC (PubMed Central)
  24. Upregulation of NKG2D ligands in acute lymphoblastic leukemia and non-Hodgkin lymphoma cells by romidepsin and enhanced in vitro and in vivo natural killer cell cytotoxicity
    Prakash Satwani, Sejal Bavishi, Aniket Saha, Frances Zhao, Janet S Ayello, Carmella van de Ven, Yaya Chu, Mitchell Stuart Cairo · 2014 · Cytotherapy
  25. New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells
    Fabien Gueugnon, Pierre‐François Cartron, Cédric Charrier, Philippe Bertrand, Jean‐François Fonteneau, Marc Grégoire, Christophe Blanquart · 2014 · Oncotarget
  26. Zyflamend, a Combination of Herbal Extracts, Attenuates Tumor Growth in Murine Xenograft Models of Prostate Cancer
    E.-Chu Huang, Michael F. McEntee, Jay Whelan · 2012 · Nutrition and Cancer
  27. A histone deacetylase inhibitor improves hypothyroidism caused by a TR 1 mutant
    Dong‐Wook Kim, Ji Won Park, Mark C. Willingham, Sheue-yann Cheng · 2013 · Human Molecular Genetics
  28. Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer
    Emre Gerçeker, Sedat Boyacıoğlu, Elmas Kasap, Ahmed Ramiz Baykan, Hakan Yüceyar, HATICE YILDIRIM, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz · 2015 · Oncology Reports
  29. Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer
    David R. Li, Hanwei Zhang, Elizabeth M. Peek, Song Wang, Lin Du, Gang Li, Arnold I. Chin · 2015 · The Journal of Urology
  30. Panobinostat for the treatment of acute myelogenous leukemia
    Fortunato Morabito, Maria Teresa Voso, Stefan Hohaus, Massimo Gentile, Ernesto Vigna, Anna Grazia Recchia, Lorenzo Iovino, E. Benedetti, Francesco Lo‐Coco, Sara Galimberti · 2016 · Expert Opinion on Investigational Drugs
  31. Indole: A Privileged Heterocyclic Moiety in the Management of Cancer
    Reyaz Hassan Mir, Roohi Mohi-ud-din, Taha Umair Wani, Mohammad Ovais Dar, Abdul Jalil Shah, Bashir Ahmad Lone, Pooja A. Chawla, Mubashir Hussain Masoodi · 2021 · Current Organic Chemistry
  32. Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.
    Lingling Chang, Mei‐Mei Kau, Wan-Song Alfred Wun, Low-Tone Ho, Paulus S. Wang · 2002 · PubMed
  33. Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells
    Hoffmann, Michèle J., Meneceur, Sarah, Hommel, Katrin, Schulz, Wolfgang A., Niegisch, Günter · 2021 · Genes
  34. ROS-responsive thioketal nanoparticles delivering system for targeted ulcerative colitis therapy with potent HDAC6 inhibitor, tubastatin A
    Prabhat Shrestha, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jee‐Heon Jeong, Simmyung Yook · 2024 · European Journal of Pharmaceutical Sciences
  35. Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea‐Based HDAC Inhibitors
    Finn Kristian Hansen, Tina S. Skinner‐Adams, Sandra Duffy, Linda Marek, Subathdrage D.M. Sumanadasa, Krystina Kuna, Jana Held, Vicky M. Avery, Katherine T. Andrews, Thomas Kurz · 2014 · ChemMedChem
  36. Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis
    Mingming Zhang, Yida Pan, Dehua Tang, Robert Gregory Dorfman, Lei Xu, Qian Zhou, Lixing Zhou, Yuming Wang, Li Yang, Yuyao Yin et al. · 2019 · Cell Communication and Signaling
  37. Modulation of serine/threonine-protein phosphatase 1 (PP1) complexes: A promising approach in cancer treatment
    Bárbara Matos, John Howl, Cármen Jerónimo, Margarida Fardilha · 2021 · Drug Discovery Today
  38. Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancer
    Sophia N. Ononye, Michael van Heyst, Eric M Falcone, A. Anderson, D. Wright · 2012 · Pharmaceutical Patent Analyst
  39. Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis
    Song Li, Baolu Wang, Yan Xu, Junjie Zhang · 2011 · Molecular Cancer
  40. TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms
    John K. Simmons, Jyoti D. Patel, Aleksandra M. Michalowski, Shuling Zhang, Bih‐Rong Wei, Patrick Sullivan, Ben Gamache, Kenneth M. Felsenstein, Walter Michael Kuehl, Richard J. Simpson et al. · 2013 · Molecular Oncology
  41. Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes
    Maxim V. Kozlov, Alla A. Kleymenova, Konstantin A. Konduktorov, Alsu Z. Malikova, Sergey N. Kochetkov · 2014 · Biochemistry (Moscow)
  42. Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study
    Jiachen Wen, Qun Niu, Jiang Liu, Yu J. Bao, Jinyu Yang, Shenglin Luan, Yinbo Fan, Dan Liu, Linxiang Zhao · 2015 · Bioorganic & Medicinal Chemistry Letters
  43. AKT activation controls cell survival in response to HDAC6 inhibition
    Maciej A. Kaliszczak, Sebastian Trousil, T Ali, Eric Ofori Aboagye · 2016 · Cell Death and Disease
  44. Strategies that regulate LSD1 for novel therapeutics
    Meng Li, Mengge Dai, Bing Cheng, Shaotong Li, Enhui Guo, Junwei Fu, Ting Ma, Bin Yu · 2024 · Acta Pharmaceutica Sinica B
  45. Determination of CK2 Specificity and Substrates by Proteome-Derived Peptide Libraries
    Chunli Wang, Mingliang Ye, Yangyang Bian, Fangjie Liu, Kai Cheng, Mingming Dong, Jing Dong, Hanfa Zou · 2013 · Journal of Proteome Research
  46. Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future Prospects
    Daniel Alencar Rodrigues, Pedro de Sena Murteira Pinheiro, Carlos Alberto Manssour Fraga · 2020 · ChemMedChem
  47. Histone Deacetylase‐Triggered Self‐Immolative Peptide‐Cytotoxins for Cancer‐Selective Drug Delivery
    Haoyu Bai, Huifang Wang, Zhuha Zhou, Ying Piao, Xiangrui Liu, Jianbin Tang, Xian Shen, Youqing Shen, Zhuxian Zhou · 2023 · Advanced Functional Materials
  48. Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222
    Stefania Terracciano, Simone Di Micco, Giuseppe Bifulco, Paola Gallinari, Raffaele Riccio, Ines Bruno · 2010 · Bioorganic & Medicinal Chemistry
  49. Understanding Histone Deacetylases in the Cancer Development and Treatment: An Epigenetic Perspective of Cancer Chemotherapy
    Mudassier Ahmad, Abid Hamid, Aashiq Hussain, Rabiya Majeed, Yasrib Qurishi, Javeed Ahmad Bhat, Rauf Ahmad Najar, Asif Khurshid Qazi, Mohammad Afzal Zargar, Shashank Kumar Singh et al. · 2012 · DNA and Cell Biology
  50. Energy-optimised pharmacophore approach to identify potential hotspots during inhibition of Class II HDAC isoforms
    Shabir Ahmad Ganai, Karthi Shanmugam, Vijayalakshmi Mahadevan · 2014 · Journal of Biomolecular Structure and Dynamics
  51. A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies.
    Wei-Jan Huang, Yen-An Tang, Mei-Yu Chen, Ying-Jan Wang, F. Hu, Tseng-Wei Wang, Shi-Wei Chao, Hui-Wen Chiu, Ya-Ling Yeh, Hsin-Yi Chang et al. · 2014 · Cancer Letters
  52. Histone Deacetylases and Their Role in Asthma
    Simon G. Royce, Tom C. Karagiannis · 2012 · Journal of Asthma
  53. Design, synthesis and primary activity assay of tripeptidomimetics as histone deacetylase inhibitors with linear linker and branched cap group
    Yingjie Zhang, Jinhong Feng, Yuping Jia, Yingying Xu, Chunxi Liu, Hao Fang, Wenfang Xu · 2011 · European Journal of Medicinal Chemistry
  54. A Chimeric SERM–Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy
    Hitisha Patel, Marton I. Siklos, Hazem Abdelkarim, Emma L. Mendonca, Aditya Sudheer Vaidya, Pavel A. Petukhov, Gregory R. J. Thatcher · 2013 · ChemMedChem
  55. Design, synthesis and biological evaluation of novel hydroxamic acids bearing artemisinin skeleton
    Vũ Thị Thu Hà, Vu Tuan Kien, Le Huy Binh, Vũ Đình Tiến, Nguyen Thi Thuy My, Nguyen‐Hai Nam, Michel Baltas, Hyunggu Hahn, Byung Woo Han, Đỗ Thị Thảo et al. · 2016 · Bioorganic Chemistry
  56. Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in hepatocellular carcinoma
    Srinivas Chatla, V. Swathi, Chiliveru Priyanka, Tangutur Anjana Devi, B. V. Subba Reddy, Mekala Janaki Ramaiah, Utpal Bhadra, Manika Pal Bhadra · 2016 · APOPTOSIS
  57. HDAC8 regulates neural differentiation through embryoid body formation in P19 cells
    Syouichi Katayama, Atsushi Morii, Juliet O. Makanga, Takayoshi Suzuki, Naoki Miyata, Tetsuya Inazu · 2018 · Biochemical and Biophysical Research Communications
  58. Total synthesis of bicyclic depsipeptides spiruchostatins C and D and investigation of their histone deacetylase inhibitory and antiproliferative activities
    Kôichi Narita, Yurie Fukui, Yui Sano, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2012 · European Journal of Medicinal Chemistry
  59. Novel molecular targets in hepatocellular carcinoma
    Ariel Ka-Man Chow, Simon Wing-Lung Yau, Lui Ng · 2020 · World Journal of Clinical Oncology
  60. New Role for Histone Deacetylase 9 in Atherosclerosis and Inflammation
    Jonathan D. Smith · 2014 · Arteriosclerosis Thrombosis and Vascular Biology
  61. Acetyl-CoA: an interplay between metabolism and epigenetics in cancer
    Hao, Yang, Yi, Qin, XiaoWu, Xu, WeiBo, Chen, GuangChen, Zu, XueMin, Chen · 2022 · Frontiers in Molecular Medicine
  62. Tetrahydro-β-carboline derivatives as potent histone deacetylase 6 inhibitors with broad-spectrum antiproliferative activity
    Xin Chen, Jiayun Wang, Peng Zhao, Baiyun Dang, Ting Liang, Raphael R. Steimbach, Aubry K. Miller, Jia Liu, Xin Wang, Tongtong Zhang et al. · 2023 · European Journal of Medicinal Chemistry
  63. Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic mice
    Ahmet Ozer, Cengiz Zubeyir Altuntas, Fuat Bicer, Kenan İzgi, Scott J. Hultgren, Guiming Liu, Firouz Daneshgari · 2015 · Pathogens and Disease
  64. Histone deacetylase inhibitor-induced cell death in bladder cancer is associated with chromatin modification and modifying protein expression: A proteomic approach
    Qingdi Quentin Li, Jian-Jiang Hao, Zheng Zhang, Iawen Hsu, Yi Liu, Zhen Tao, Keidren Lewi, Adam R. Metwalli, Piyush Kumar Agarwal · 2016 · International Journal of Oncology
  65. Using Zebrafish to Study Kidney Development and Disease
    Stephanie Jerman, Zhaoxia Sun · 2017 · Current topics in developmental biology/Current Topics in Developmental Biology
  66. Synthesis of N′-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV)
    Maxim V. Kozlov, Konstantin A. Konduktorov, Anastasia S. Shcherbakova, Sergey N. Kochetkov · 2019 · Bioorganic & Medicinal Chemistry Letters
  67. Molecular targets in cancer prevention by 4-(methylthio)butyl isothiocyanate - A comprehensive review
    Davinder Pal Singh, Rohit Arora, Astha Bhatia, H.B. Singh, Balbir Singh, Saroj Arora · 2019 · Life Sciences
  68. The metabolic addiction of cancer stem cells
    Om Saswat Sahoo, Karthikeyan Pethusamy, Tryambak Pratap Srivastava, Joyeeta Talukdar, Mohammed Saeed Alqahtani, Mohamed Abd Elhamid Abbas, Ruby Dhar, Subhradip Karmakar · 2022 · Frontiers in Oncology
  69. Histone acetyltransferases and histone deacetyl transferases play crucial role during oogenesis and early embryo development
    Nazlıcan Bozdemir, Fatma Uysal · 2023 · genesis
  70. HDAC11: A novel target for improved cancer therapy
    Yan Liu, Xuechao Tong, Weina Hu, Da Chen · 2023 · Biomedicine & Pharmacotherapy
  71. Design, synthesis and antiproliferative activities of novel benzamides derivatives as HDAC inhibitors
    Yanyang Li, Yongzhen Wang, Ning Xie, Ming Xu, Pengyu Qian, Yanjin Zhao, Shuxin Li · 2015 · European Journal of Medicinal Chemistry
  72. Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring
    Frédérik Oger, Aurélien Lecorgne, Elisa Sala, Vanessa Nardese, Florence Demay, Soizic Chevance, Danielle C. Desravines, Nataliia Aleksandrova, Rémy Le Guével, Simone Lorenzi et al. · 2010 · Journal of Medicinal Chemistry
  73. Epigenetic marks in melanoma
    Hunter W. Richards, Estela E. Medrano · 2008 · Pigment Cell & Melanoma Research
  74. Identification of Histone Deacetylase 1 Protein Complexes in Liver Cancer Cells
    Muhammad Farooq, Wael Nabil Hozzein, Elsayed A. Elsayed, Nael Abu Taha, Mohammad A.M. Wadaan · 2013 · Asian Pacific Journal of Cancer Prevention
  75. Design, synthesis and biological evaluation of 2-amino-N-(2-aminophenyl)thiazole-5-carboxamide derivatives as novel Bcr-Abl and histone deacetylase dual inhibitors
    Xin Chen, Shuang Zhao, Yichao Wu, Yadong Chen, Tao Lu, Yong Zhu · 2016 · RSC Advances
  76. Methods for the expression, purification, and crystallization of histone deacetylase 6–inhibitor complexes
    J.D. Osko, David W. Christianson · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
  77. OIP5‑AS1 modulates epigenetic regulator HDAC7 to enhance non‑small cell lung cancer metastasis via miR‑140‑5p
    Jiazhuan Mei, Guiju Liu, Wenhui Wang, Peng Xiao, Dan Yang, Hua Bai, Ruijun Li · 2020 · Oncology Letters
  78. Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments
    László Petri, Péter Ábrányi‐Balogh, Tı́mea Imre, Gyula Pálfy, András Perczel, Damijan Knez, Martina Hrast, Martina Gobec, Izidor Sosič, Kinga Nyíri et al. · 2020 · ChemBioChem
  79. HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCs
    Jianping Zhang, Zhi-Xue Yang, Feng Zhang, Ya-Wen Fu, Xinyue Dai, Wei Wen, Beldon Zhang, Hannah Choi, Wanqiu Chen, Meredith Brown et al. · 2021 · Science China Life Sciences
  80. Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer
    Enerlyn Lozada, Zdeněk Andrysík, Moying Yin, Nicholas Redilla, Kathryn Rice, Peter J. Stambrook · 2016 · Oncotarget
  81. Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups
    Gustavo Salgado Pires, Heber Victor Tolomeu, Daniel Alencar Rodrigues, Lı́dia Moreira Lima, Carlos Alberto Manssour Fraga, Pedro de Sena Murteira Pinheiro · 2025 · Pharmaceuticals
  82. Selective histone deacetylase 6 inhibition prolongs survival in a lethal two-hit model
    Xin Min Cheng, Zhengcai Liu, Baoling Liu, Ting Zhao, Yongqing Li, Hasan Badre Alam · 2015 · Journal of Surgical Research
  83. Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistance
    Shabir Ahmad Ganai · 2016 · Pharmaceutical Biology
  84. RETRACTED ARTICLE: Fluoxetine induces apoptosis through endoplasmic reticulum stress via mitogen-activated protein kinase activation and histone hyperacetylation in SK-N-BE(2)-M17 human neuroblastoma cells
    Ji Hyun Choi, Yeon Ju Jeong, Ah-Ran Yu, Kyung‐Sik Yoon, Wonchae Choe, Joohun Ha, Sung Soo Kim, Eui‐Ju Yeo, Insug Kang · 2017 · APOPTOSIS · Retracted
  85. LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells
    Li Li, Fengyang Li, Xiuhong Hu, Zengshuai Wu, Wenbo Ren, Tingting Wang, Zhengchao Ji, Na Li, Jingmin Gu, Changjiang Sun et al. · 2022 · BMC Cancer
  86. A Reactivity‐Tunable Self‐Immolative Design Enables Histone Deacetylase‐Targeted Imaging and Prodrug Activation
    Feng Liu, Xu Ding, Xiaobo Xu, Fenglin Wang, Xia Chu, Jian‐Hui Jiang · 2022 · Angewandte Chemie International Edition
  87. Three single nucleotide variants of the HDAC gene are associated with type 2 diabetes mellitus in a Chinese population: A community-based case–control study
    Zhuanping Zeng, Rifang Liao, Zhenjiang Yao, Weiping Zhou, Ping Ye, Xueyan Zheng, Xing Li, Yanhui Huang, Sidong Chen, Qing Chen · 2013 · Gene
  88. Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition
    Maciej Purwin, J. Hernández-Toribio, Claire Coderch, Rostyslav R. Panchuk, Nadia R. Skorokhyd, Kamila Filipiak, Beatriz de Pascual‐Teresa, Ana Ramos · 2016 · RSC Advances
  89. A comparative study based on docking and molecular dynamics simulations over HDAC-tubulin dual inhibitors
    Malihe Hassanzadeh, Kowsar Bagherzadeh, Massoud Amanlou · 2016 · Journal of Molecular Graphics and Modelling
  90. A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancer
    Jiunn-Min Shieh, Yen-An Tang, Fu-Han Hu, Wei‐Jan Huang, Ying-Jan Wang, Jayu Jen, Shengyou Liao, Ying-Hung Lu, Ya-Ling Yeh, Tseng-Wei Wang et al. · 2017 · International Journal of Cancer
  91. Design, synthesis and biological evaluation of novel hydroxamic acid based histone deacetylase 6 selective inhibitors bearing phenylpyrazol scaffold as surface recognition motif
    Jinyu Yang, Gaoliang Cheng, Qihao Xu, Shenglin Luan, Shuxiang Wang, Dan Liu, Linxiang Zhao · 2017 · Bioorganic & Medicinal Chemistry
  92. Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress
    Chung-Che Wu, Pin-Tse Lee, Tzu‐Jen Kao, Szu‐Yi Chou, Ruei-Yuan Su, Yi‐Chao Lee, Shiu-Hwa Yeh, Jing‐Ping Liou, Tsung‐I Hsu, Tsung‐Ping Su et al. · 2018 · Redox Biology
  93. Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells
    Yodita Asfaha, Christian Schrenk, Leandro A. Alves Avelar, Friedrich Lange, Chenyin Wang, Jan Josef Bandolik, Alexandra Hamacher, Matthias Ulrich Kassack, Thomas Kurz · 2019 · Bioorganic & Medicinal Chemistry
  94. Development and validation of a sensitive HPLC–MS/MS method for determination of chidamide (epidaza), a new benzamide class of selective histone deacetylase inhibitor, in human plasma and its clinical application
    Ruolan Gu, Taoyun Liu, Xiaoxia Zhu, Hui Kong Gan, Zhuona Wu, Jian Li, Ying Zheng, Guifang Dou, Zhiyun Meng · 2015 · Journal of Chromatography B
  95. HDAC6 serves as a biomarker for the prognosis of patients with renal cell carcinoma
    Zijian Zhang, Yanwei Cao, Weiming Zhao, Lei Guo, Wanpeng Liu · 2017 · Cancer Biomarkers
  96. Recent advances in dual PROTACs degrader strategies for disease treatment
    Jianyu Liu, Yanzhuo Liu, Jiao Tang, Qianyuan Gong, Guoyi Yan, Hengrui Fan, Xueping Zhang, Chunlan Pu · 2024 · European Journal of Medicinal Chemistry
  97. Lactate metabolism and lactylation in breast cancer: mechanisms and implications
    Yifan Qiao, Yijia Liu, Ran Ran, Yan Zhou, J Y Gong, Lijuan Liu, Yusi Zhang, Hui Wang, Yuan Fan, Yihan Fan et al. · 2025 · Cancer and Metastasis Reviews
  98. Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumors
    Manuraj Pandey, Sarwat Sultana, Krishna Prakash Gupta · 2013 · Experimental and Molecular Pathology
  99. AR-42 induces apoptosis in human hepatocellular carcinoma cells via HDAC5 inhibition
    Mingming Zhang, Yida Pan, Robert G. Dorfman, Zhaogui Chen, Fuchen Liu, Qian Zhou, Shan Hong Huang, Jun Zhang, Dongqin Yang, Jie Liu · 2016 · Oncotarget
  100. Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents
    Duong Tien Anh, Hai Pham‐The, Do Thi Mai Dung, Phan Thị Phương Dung, Huong Le‐Thi‐Thu, Eun Jae Park, Hye Won Jun, Jong Soon Kang, Joo‐Hee Kwon, Trương Thanh Tùng et al. · 2020 · Bioorganic & Medicinal Chemistry Letters