HDAC family: What are the cancer relevant targets?

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Items 501–600 of 1,000

1. Advances in the Design and Development of PROTAC-mediated HDAC Degradation
   Daniel Alencar Rodrigues, Andrew J. Roe, Darren M. Griffith, Tríona Ní Chonghaile · 2021 · Current Topics in Medicinal Chemistry
2. Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents
   Haoting Zheng, Qiuzi Dai, Zigao Yuan, Tingting Fan, Cunlong Zhang, Zijian Liu, Bizhu Chu, Qinsheng Sun, Yan Chen, Yuyang Jiang · 2021 · Bioorganic & Medicinal Chemistry
3. In vitro Model Systems for Studies Into Retinal Neuroprotection
   Yu Zhu, Bowen Cao, Arianna Tolone, Jie Yan, Gustav Christensen, Blanca Arango‐González, Marius Ueffing, François Paquet‐Durand · 2022 · Frontiers in Neuroscience
4. A bionic multichannel nanofiber conduit carrying Tubastatin A for repairing injured spinal cord
   Shiyang Liao, Yonghang Liu, Yanlong Kong, Haitao Shi, Bitong Xu, Bo Tang, Congbin Li, Yitian Chen, Jing Chen, Juan Du et al. · 2022 · Materials Today Bio
5. Mitochondrial Apoptosis and FAK Signaling Disruption by a Novel Histone Deacetylase Inhibitor, HTPB, in Antitumor and Antimetastatic Mouse Models
   Jiunn-Min Shieh, Tzu-Tang Wei, Yen-An Tang, Sin-Ming Huang, Wei-Ling Wen, Meiyu Chen, Hung-Chi Cheng, Santosh B. Salunke, Ching‐Shih Chen, Pinpin Lin et al. · 2012 · PLoS ONE
6. Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: “To Be or Not to Be Acetylated”?
   Sebastian Stintzing, Ralf Kemmerling, Tobias Kiesslich, Beate Alinger, Matthias Ocker, Daniel Neureiter · 2011 · BioMed Research International
7. Histones: Controlling Tumor Signaling Circuitry
   Manoela D. Martins Rogerio M. Castilho · 2013 · Journal of Carcinogenesis & Mutagenesis
8. Inhibition of histone deacetylase 6 restores intestinal tight junction in hemorrhagic shock
   Zhigang Chang, Yongqing Li, Wei He, Baoling Liu, Xiuzhen Duan, Ihab F. Halaweish, Ted Bambakidis, Baihong Pan, Yingjian Liang, Vahagn C. Nikolian et al. · 2016 · The Journal of Trauma: Injury, Infection, and Critical Care
9. Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN
   Guanhua Zhang, Yehua Gan · 2017 · Oncology Reports
10. Highly fluorescent and HDAC6 selective scriptaid analogues
    Cassandra L. Fleming, Anthony L. Natoli, Jeannette Schreuders, Mark G. Devlin, Prusothman Yoganantharajah, Yann Gibert, Kathryn G. Leslie, Elizabeth J. New, Trent D. Ashton, Frederick Matthew Pfeffer · 2018 · European Journal of Medicinal Chemistry
11. Current discovery strategies for hepatocellular carcinoma therapeutics
    Qiuzi Dai, Cunlong Zhang, Zigao Yuan, Qinsheng Sun, Yuyang Jiang · 2019 · Expert Opinion on Drug Discovery
12. HDAC4 Regulates the Proliferation, Differentiation and Apoptosis of Chicken Skeletal Muscle Satellite Cells
    Jing Zhao, Xiaoxu Shen, Xinao Cao, Haorong He, Shunshun Han, Yuqi Chen, Can Cui, Yuanhang Wei, Yan Wang, Diyan Li et al. · 2020 · Animals
13. Sulforaphane Potentiates Gemcitabine-Mediated Anti-Cancer Effects against Intrahepatic Cholangiocarcinoma by Inhibiting HDAC Activity
    Fumimasa Tomooka, Kosuke Kaji, Norihisa Nishimura, Takahiro Kubo, Satoshi Iwai, Akihiko Shibamoto, Junya Suzuki, Koh Kitagawa, Tadashi Namisaki, Takemi Akahane et al. · 2023 · Cells
14. Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors
    Wei Yang, Lixuan Li, Xun Ji, Xiaowei Wu, Mingbo Su, Sheng Li, Yi Zang, Jia Xuan Li, Hong Liu · 2014 · Bioorganic & Medicinal Chemistry
15. HDAC8 as a target in drug discovery: Function, structure and design
    Qianlong Zhao, Hongyan Liu, Jie Peng, Haoqian Niu, Jingqian Liu, Haoyu Xue, Wenjia Liu, Xinyu Liu, Huabei Hao, Xinbo Zhang et al. · 2024 · European Journal of Medicinal Chemistry
16. Crucial role of HO-1/IRF4-dependent apoptosis induced by panobinostat and lenalidomide in multiple myeloma
    Sishi Tang, Dan Ma, Bingqing Cheng, Qing Fang, Xingyi Kuang, Kunlin Yu, Weili Wang, Bo Hu, Jishi Wang · 2018 · Experimental Cell Research
17. A Review on Molecular Docking on HDAC Isoforms: Novel Tool for Designing Selective Inhibitors
    Aliki Drakontaeidi, Eleni A. Pontiki · 2023 · Pharmaceuticals
18. Histone deacetylase 5 promotes the migration and invasion of hepatocellular carcinoma via increasing the transcription of hypoxia-inducible factor-1α under hypoxia condition
    Ming Ye, Zejun Fang, Hongqian Gu, Rui Yin Song, Jiangwei Ye, Hongzhang Li, Zhiguang Wu, Shenghui Zhou, Peng Li, Xiang Cai et al. · 2017 · Tumor Biology
19. Overexpression of HDAC6, but not HDAC3 and HDAC4 in the penumbra after photothrombotic stroke in the rat cerebral cortex and the neuroprotective effects of α-phenyl tropolone, HPOB, and sodium valproate
    Svetlana Viktorovna Demyanenko, Valentina Dzreyan, Anatoly B. Uzdensky · 2020 · Brain Research Bulletin
20. An atlas of histone deacetylase expression in breast cancer: fluorescence methodology for comparative semi-quantitative analysis.
    Katherine Ververis, Tom C. Karagiannis · 2012 · PubMed Central
21. A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold
    Melissa M. Kemp, Qiu Wang, Jason H. Fuller, Nathan H. West, Nicole M. Martínez, Elizabeth M. Morse, Michel Weïwer, Stuart L. Schreiber, James E. Bradner, Angela N. Koehler · 2011 · Bioorganic & Medicinal Chemistry Letters
22. Histone Acetylation and Deacetylation
    Daniel M. Fass, Melissa M. Kemp, Frederick A. Schroeder, Florence F. Wagner, Qiu Wang, Edward B. Holson · 2012 · Wiley-VCH eBooks
23. HDAC11 inhibition disrupts porcine oocyte meiosis via regulating α-tubulin acetylation and histone modifications
    Rong Huang, Liyan Sui, Cong Fu, Yanhui Zhai, Xiangpeng Dai, Sheng Zhang, Ziyi Li · 2021 · Aging
24. Progress in discovery and development of natural inhibitors of histone deacetylases (HDACs) as anti-cancer agents
    Abhishek Wahi, Priti Jain, Apurba Sinhari, Hemant R. Jadhav · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
25. Mechanisms and Advances of Epigenetic Regulation in Cardiovascular Disease
    Xiaojun Wang, Xusheng Teng, Chao Luo, Laifa Kong · 2024 · Frontiers in Bioscience-Landmark
26. Discovery of Pyridone‐Based Histone Deacetylase Inhibitors: Approaches for Metabolic Stability
    Misun Cho, Eunhyun Choi, Jee Sun Yang, Chulho Lee, Jeong Jea Seo, Beom Seok Kim, Soo Jin Oh, Hwan Mook Kim, Kiho Lee, Song‐Kyu Park et al. · 2013 · ChemMedChem
27. Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy
    Zhe Yang, Lin Zhou, Li-Ming Wu, Haiyang Xie, Feng Zhang, Shusen Zheng · 2010 · Clinical Chemistry and Laboratory Medicine (CCLM)
28. Depletion of histone deacetylase 3 antagonizes PI3K-mediated overgrowth through the acetylation of histone H4 at lysine 16
    Wenwen Lv, Hui-Min Wei, Da-Liang Wang, Jian‐Quan Ni, Fang-Lin Sun · 2012 · Journal of Cell Science
29. A Highly Potent and Selective Histone Deacetylase 6 Inhibitor Prevents DSS-Induced Colitis in Mice
    Ting Liu, Renping Wang, Haojie Xu, Yunlong Song, Yunpeng Qi · 2017 · Biological and Pharmaceutical Bulletin
30. Exploration of some indole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents
    Trần Thị Lan Hương, Le Van Cuong, Phạm Thu Hương, Tran Phuong Thao, Huong Le‐Thi‐Thu, Phan Thị Phương Dung, Dao Thi Kim Oanh, Nguyễn Thị Mai Hương, Hoang-Van Quan, Tran Khac Vu et al. · 2017 · Chemical Papers
31. Identification of differentially expressed genes in pancreatic ductal adenocarcinoma and normal pancreatic tissues based on microarray datasets
    Liying Liu, Siqi Wang, Chunyuan Cen, Shuyi Peng, Yan Chen, Xin Li, Nan Diao, Qian Li, Ling Ma, Ping Han · 2019 · Molecular Medicine Reports
32. The clinical significance of histone deacetylase-8 in human breast cancer
    Golebagh Rahmani, Saba Sameri, Nooshin Abbasi, Mohammad Abdi, Rezvan Najafi · 2021 · Pathology - Research and Practice
33. Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2)
    Taotao Feng, Hai Wang, Hong Lin Su, Hui Lu, Li‐Qin Yu, Xiaojin Zhang, Haopeng Sun, Qidong You · 2013 · Bioorganic & Medicinal Chemistry
34. RETRACTED: Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells
    Caroline Elizabeth Ford, Elin J. Ekström, Tommy Andersson · 2009 · Proceedings of the National Academy of Sciences · Retracted
35. HDAC3 is required for XPC recruitment and nucleotide excision repair of DNA damage induced by UV irradiation
    Nishimoto, Koji, Niida, Hiroyuki, Uchida, Chiharu, Ohhata, Tatsuya, Kitagawa, Kyoko, Motegi, Akira, Suda, Takafumi, Kitagawa, Masatoshi · 2020 · Molecular Cancer Research
36. RETRACTED ARTICLE: Discovery of novel benzohydroxamate-based histone deacetylase 6 (HDAC6) inhibitors with the ability to potentiate anti-PD-L1 immunotherapy in melanoma
    Xiaopeng Peng, Ziwen Yu, Goverdhan Surineni, Bulian Deng, Meizhu Zhang, Chuan Li, Zhiqiang Sun, Wanyi Pan, Yao Liu, Shenglan Liu et al. · 2023 · Journal of Enzyme Inhibition and Medicinal Chemistry · Retracted
37. Designing proliferating cell population models with functional targets for control by anti-cancer drugs
    Frédérique Billy, Jean Clairambault · 2013 · Discrete and Continuous Dynamical Systems - B
38. Recently Identified and Potential Targets for Colon Cancer Treatment
    Michael Anthony Lea · 2010 · Future Oncology
39. Divergent kinetics differentiate the mechanism of action of two HDAC inhibitors.
    A. Kral, Nicole D. S. Ozerova, Joshua Close, Joon Jung, M. Chénard, Judith C. Fleming, B. Haines, P. Harrington, J. Maclean, Thomas A. Miller et al. · 2014 · Biochemistry
40. Synergistic Activity of N-hydroxy-7-(2-naphthylthio) Heptanomide and Sorafenib Against Cancer Stem Cells, Anaplastic Thyroid Cancer
    Ki Cheong Park, Seok‐Mo Kim, Jeong Yong Jeon, Bup‐Woo Kim, Hyeung Kyoo Kim, Ho Jin Chang, Yong Sang Lee, Kim Sk, Seung Hoon Choi, Cheong Soo Park et al. · 2017 · Neoplasia
41. Overexpression of HDAC6 suppresses tumor cell proliferation and metastasis by inhibition of the canonical Wnt/β‑catenin signaling pathway in hepatocellular carcinoma
    Zhusheng Yin, Wei Xu, Hao Xu, Junnian Zheng, Yuming Gu · 2018 · Oncology Letters
42. Design, synthesis and biological evaluation of novel thioquinazolinone-based 2-aminobenzamide derivatives as potent histone deacetylase (HDAC) inhibitors
    Chunhui Cheng, Fan Yun, Jie He, Sadeeq Ullah, Qipeng Yuan · 2019 · European Journal of Medicinal Chemistry
43. Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors
    Hao Hu, Fei Chen, Yuhong Dong, Ming Li, Sicong Xu, Mingze Qin, Ping Gong · 2020 · European Journal of Medicinal Chemistry
44. HDAC3 regulates stability of estrogen receptor α mRNA
    Shohei Oie, Kazuya Matsuzaki, Wataru Yokoyama, Akiko Murayama, Junn Yanagisawa · 2013 · Biochemical and Biophysical Research Communications
45. Primary Macrophages Rely on Histone Deacetylase 1 and 2 Expression To Induce Type I Interferon in Response to Gammaherpesvirus Infection
    Bryan C. Mounce, Wadzanai P. Mboko, Adam J. Kanack, Vera L. Tarakanova · 2013 · Journal of Virology
46. Design of Selective Histone Deacetylase Inhibitors: Rethinking Classical Pharmacophore
    Jelena Melesina, Lucas Praetorius, Conrad Veranso Simoben, Dina Robaa, Wolfgang Sippl · 2018 · Future Medicinal Chemistry
47. Clinical significance of HDAC1, -2 and -3 expression levels in esophageal squamous cell carcinoma
    Huiwu Li, Hui Li, Waresijiang Yibulayin, Yan Chen, Ying Li, Liang Yu, Yike Li, Ling Liu · 2020 · Experimental and Therapeutic Medicine
48. The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development
    Michael James Hitchler, Frederick E. Domann · 2021 · Free Radical Biology and Medicine
49. Effect of vorinostat on INK4 family and HDACs 1, 2, and 3 in pancreatic cancer and hepatocellular carcinoma
    Masumeh Sanaei, Fraidoon Kavoosi · 2021 · Research in Pharmaceutical Sciences
50. Discovery of ( S )- N -(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6 H )-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
    Da‐Qiang Li, Zhuo Zhang, Yalei Li, Xinyi Wang, Hanyue Zhong, Huajie Yang, Yong Xi, Hong‐Chun Liu, Aijun Shen, Youhong Hu · 2023 · Journal of Medicinal Chemistry
51. Methylation and gene expression of histone deacetylases 6 in systemic lupus erythematosus
    Tzu‐Jung Fang, Yuan‐Zhao Lin, Ching‐Ching Liu, Chia‐Hui Lin, Ruei‐Nian Li, Cheng‐Chin Wu, Tsan‐Teng Ou, Wen‐Chan Tsai, Jeng‐Hsien Yen · 2015 · International Journal of Rheumatic Diseases
52. Novel 2-oxoindoline-based hydroxamic acids: synthesis, cytotoxicity, and inhibition of histone deacetylation
    Trần Thị Lan Hương, Do Thi Mai Dung, Phan Thị Phương Dung, Phung Thanh Huong, Tran Khac Vu, Hyunggu Hahn, Byung Woo Han, Jisung Kim, Minji Pyo, Sang‐Bae Han et al. · 2015 · Tetrahedron Letters
53. A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells
    Liyan Yang, Qiannan Liang, Ke Shen, Li Ma, Na An, Weiping Deng, Zhewei Fei, Jianwen Liu · 2015 · Biomedicine & Pharmacotherapy
54. Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation
    Sung‐Keum Seo, Chang-Sun Hwang, Taeboo Choe, Seok‐Il Hong, Jae Youn Yi, Sang‐Gu Hwang, Hyun-Gyu Lee, Sang Taek Oh, Yun‐Han Lee, In‐Chul Park · 2014 · Oncotarget
55. Targeting the Post-translational Proteome with Intrabodies
    Antonino Cattaneo, Michele Chirichella · 2018 · Trends in biotechnology
56. Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity
    Wenwen Duan, Jinning Hou, Xiaojing Chu, Xiaoqian Li, Jian Zhang, Jin Li, Wenfang Xu, Yingjie Zhang · 2015 · Bioorganic & Medicinal Chemistry
57. Creating zinc monkey wrenches in the treatment of epigenetic disorders
    Jay H. Kalin, Kyle Vincent Butler, Alan P. Kozikowski · 2009 · Current Opinion in Chemical Biology
58. Histone deacetylase 6 activity is critical for the metastasis of Burkitt’s lymphoma cells
    Ning Ding, Lingyan Ping, Lixia Feng, Xiaohui Zheng, Yuqin Song, Jun Zhu · 2014 · Cancer Cell International
59. Oroxylin A, a natural anticancer flavonoid compound, induces differentiation of t(8;21)-positive Kasumi-1 and primary acute myeloid leukemia cells
    Hui Hui, Xiaoxiao Zhang, Hui Li, Xiao Liu, Le Shen, Yu Zhu, Jingyan Xu, Qinglong Guo, Na Lu · 2016 · Journal of Cancer Research and Clinical Oncology
60. Evaluation of Anti-Tumor Efficacy of Vorinostat Encapsulated Self-Assembled Polymeric Micelles in Solid Tumors
    Sri Vishnu Kiran Rompicharla, Prakruti Trivedi, Preeti Kumari, Omkara Swami Muddineti, Sowmya Theegalapalli, Balaram Ghosh, Swati Biswas · 2018 · AAPS PharmSciTech
61. Effects of histone deacetylase inhibitors on ATP‑binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells
    Hao Wang, Chun‐Hua Chi, Ying Zhang, Bin Shi, Ru Jia, Ben-Jun Wang · 2019 · Oncology Letters
62. HDAC-an important target for improving tumor radiotherapy resistance
    Rui Ling, Jingzhi Wang, Yuan Fang, Yunpeng Yu, Yuting Su, Wen Sun, Xiaoqin Li, Xiang Tang · 2023 · Frontiers in Oncology
63. Quinazoline‐chalcone hybrids as HDAC/EGFR dual inhibitors: Design, synthesis, mechanistic, and in‐silico studies of potential anticancer activity against multiple myeloma
    Mostafa A. Mansour, Asmaa M. AboulMagd, Samar H. Abbas, Mohamed Abdel‐Aziz, Hamdy Mohamed Abdel-Rahman · 2024 · Archiv der Pharmazie
64. Interplay between acetylation and ubiquitination controls PSAT1 protein stability in lung adenocarcinoma
    Yuhan Liu, Wenze Xun, Tao Zhao, Meng-lin Huang, Longhua Sun, Guilan Wen, Xiuhua Kang, Jianbin Wang, Tianyu Han · 2024 · Communications Biology
65. Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase Degraders
    Felix Feller, Irina Honin, Martina Miranda, Heiko B. Weber, Svenja Henze, Maria Hanl, Finn K. Hansen · 2025 · Journal of Medicinal Chemistry
66. Histone Deacetylase Inhibition Impairs Normal Intestinal Cell Proliferation and Promotes Specific Gene Expression
    Alireza Roostaee, Amel Guezguez, Marco Beauséjour, Aline Simoneau, Pierre H. Vachon, Emile H. Levy, Jean‐François Beaulieu · 2015 · Journal of Cellular Biochemistry
67. Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer
    Kenneth E. Huffman, Elisabeth D. Martínez · 2013 · Frontiers in Oncology
68. Zyflamend, a polyherbal mixture, down regulates class I and class II histone deacetylases and increases p21 levels in castrate-resistant prostate cancer cells
    E‐Chu Huang, Yi Zhao, Guoxun Chen, Seung Joon Baek, Michael F. McEntee, Steven C. Minkin, John Biggerstaff, Jay N. Whelan · 2014 · BMC Complementary and Alternative Medicine
69. Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding
    Sugunadevi Sakkiah, Chandrasekaran Meganathan, Yuno Lee, Songmi Kim, Keun Woo Lee · 2012 · Journal of Biomolecular Structure and Dynamics
70. Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development
    Sara Loponte, Chiara V. Segré, Silvia Senese, Claudia Miccolo, Stefano Santaguida, Gianluca Deflorian, Simona Citro, Domenico Mattoscio, Federica Pisati, M. Moser et al. · 2016 · Scientific Reports
71. Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model
    Jay H. Kalin, Abdulkerim Eroglu, Hua Liu, Walter David Holtzclaw, Irene M. Leigh, Charlotte M. Proby, Jed W. Fahey, Philip A. Cole, Albena T. Dinkova‐Kostova · 2019 · PLoS ONE
72. Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement
    Smita Salian‐Mehta, Mei Xu, Timothy A. McKinsey, Stuart A. Tobet, Margaret E. Wierman · 2015 · Journal of Biological Chemistry
73. Epigenetic Regulation of Cell Signaling Pathways in Acute Lymphoblastic Leukemia
    Edurne San José‐Eneriz, Xabier Agirre, Paula Rodríguez‐Otero, Felipe Prósper · 2013 · Epigenomics
74. DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells
    Lena Nordström, Elin Andersson, Venera Kuci Emruli, Elin Gustavsson, Karolina Holm, Markus Ringnér, Per Guldberg, Sara Ek · 2015 · BMC Cancer
75. HDAC5 Inhibitors as a Potential Treatment in Breast Cancer Affecting Very Young Women
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76. Deactylase inhibition in myeloproliferative neoplasms
    Sridurga Mithraprabhu, George Grigoriadis, Tiffany T. Khong, Andrew G Spencer · 2010 · Investigational New Drugs
77. Honokiol from Magnolia spp. induces G1 arrest via disruption of EGFR stability through repressing HDAC6 deacetylated Hsp90 function in lung cancer cells
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78. HDACiDB: a database for histone deacetylase inhibitors
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79. 13th Annual Meeting of the Safety Pharmacology Society: focus on novel technologies and safety pharmacology frontiers
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80. RETRACTED ARTICLE: MicroRNA-216b is Down-Regulated in Human Gastric Adenocarcinoma and Inhibits Proliferation and Cell Cycle Progression by Targeting Oncogene HDAC8
    Ying Wang, Po Xu, Jun Yao, Ruina Yang, Zhenguo Shi, Xiaojuan Zhu, Xiaoshan Feng, Shegan Gao · 2015 · Targeted Oncology · Retracted
81. Novel 4-Oxoquinazoline-BasedN-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation
    Duong Tien Anh, Hai Pham‐The, Le D. Huy, Hoàng Bảo Ngọc, Trinh T. M. Ngoc, Do Thi Mai Dung, Eun J. Park, In K. Song, Jong Soon Kang, Joo‐Hee Kwon et al. · 2021 · ACS Omega
82. Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway
    Bo Wang, Song Gong, Lizhi Han, Wenkai Shao, Zilin Li, Jiawei Xu, Xiao Lv, Baojun Xiao, Yong Feng · 2022 · Clinical Interventions in Aging
83. Rational design of metabolically stable HDAC inhibitors: An overhaul of trifluoromethyl ketones
    Riddhidev Banerjee, Endri Karaj, Sabitri Lamichhane, Lauren N. Kotsull, Nishanth Kuganesan, Dragan Isailović, Mary Kay H. Pflum, James T. Slama, Taylor William, L. M. Viranga Tillekeratne · 2022 · European Journal of Medicinal Chemistry
84. Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors
    Felix Feller, Finn K. Hansen · 2023 · ACS Medicinal Chemistry Letters
85. Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor
    Loredana Vesci, Elena Bernasconi, Ferdinando Maria Milazzo, Rita De Santis, Eugenio Gaudio, Ivo Kwee, Andrea Rinaldi, Silvia Pace, Valeria Carollo, Giuseppe Giannini et al. · 2014 · Oncotarget
86. Histone Deacetylase Inhibitory Activity of Peanut Testa Extracts against Human Cancer Cell Lines
    Somprasong Khaopha, Sanun Jogloy, A. Patanothai, Thanaset Senawong · 2015 · Journal of Food Biochemistry
87. The DAC system and associations with multiple myeloma
    Enrique M. Ocio, Jesús F. San Miguel · 2010 · Investigational New Drugs
88. Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity
    Xiaoyang Li, Jinning Hou, Xiaoguang Li, Yuqi Jiang, Xueliang Liu, Weiwei Mu, Yiming Jin, Yingjie Zhang, Wenfang Xu · 2014 · European Journal of Medicinal Chemistry
89. A Conserved Gammaherpesvirus Protein Kinase Targets Histone Deacetylases 1 and 2 To Facilitate Viral Replication in Primary Macrophages
    Bryan C. Mounce, Wadzanai P. Mboko, Tarin M. Bigley, Scott S. Terhune, Vera L. Tarakanova · 2013 · Journal of Virology
90. Histone Deacetylase (HDAC) Inhibitors Down-Regulate Endothelial Lineage Commitment of Umbilical Cord Blood Derived Endothelial Progenitor Cells
    Florin Iordache, Cosmin Alexandru Buzilă, Andrei Alexandru Constantinescu, Eugen Andrei, Horia Maniu · 2012 · International Journal of Molecular Sciences
91. Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis
    Mingming Zhang, Yuyao Yin, Robert G. Dorfman, Tianhui Zou, Yida Pan, Yang Li, Yuming Wang, Qian Zhou, Lixing Zhou, Bo Kong et al. · 2017 · Oncotarget
92. Total synthesis of burkholdacs A and B and 5,6,20-tri-epi-burkholdac A: HDAC inhibition and antiproliferative activity
    Yurie Fukui, Kôichi Narita, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh · 2014 · European Journal of Medicinal Chemistry
93. HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines
    Tobias Solli Iveland, Lars Hagen, Animesh Sharma, Mirta Mittelstedt Leal de Sousa, Antonio Sarno, Kristian Lied Wollen, Nina‐Beate Liabakk, Geir Slupphaug · 2020 · Journal of Translational Medicine
94. Inhibition of histone deacetylases, topoisomerases and epidermal growth factor receptor by metal-based anticancer agents: Design & synthetic strategies and their medicinal attributes
    Manpreet Kaur, Loveleen, Raj Kumar · 2020 · Bioorganic Chemistry
95. Pharmacological Studies on Cinnamic Alcohol and Its Derivatives
    Álefe Brito Monteiro, Humberto Hugo Nunes de Andrade, Cícero Francisco Bezerra Felipe, Reinaldo Nóbrega de Almeida · 2021 · Revista Brasileira de Farmacognosia
96. An Assessment on Ethanol-Blended Gasoline/Diesel Fuels on Cancer Risk and Mortality
    Steffen Mueller, Gail Dennison, Shujun Liu · 2021 · International Journal of Environmental Research and Public Health
97. Vorinostat-Like Molecules as Structural, Stereochemical, and Pharmacological Tools
    Stephen Hanessian, Luciana Auzzas, Andreas Larsson, Jianbin Zhang, Giuseppe Giannini, Grazia Gallo, Andrea Ciacci, Walter Cabri · 2010 · ACS Medicinal Chemistry Letters
98. Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors
    Yingjie Zhang, Jinhong Feng, Chunxi Liu, Hao Fang, Wenfang Xu · 2011 · Bioorganic & Medicinal Chemistry
99. Pyridine hydroxamic acids are specific anti-HCV agents affecting HDAC6
    Maxim V. Kozlov, Alla A. Kleymenova, Lyudmila I. Romanova, Konstantin A. Konduktorov, Kamila A. Kamarova, Olga A. Smirnova, Vladimir Prassolov, Sergey N. Kochetkov · 2015 · Bioorganic & Medicinal Chemistry Letters
100. Repression of telomerase gene promoter requires human‐specific genomic context and is mediated by multiple HDAC1‐containing corepressor complexes
     De Cheng, Yuanjun Zhao, Shuwen Wang, Fan Zhang, Mariano Russo, Steven B. McMahon, Jiyue Zhu · 2016 · The FASEB Journal