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The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Wound healing performance of PCL/chitosan based electrospun nanofiber electrosprayed with curcumin loaded chitosan nanoparticles

Fahimirad, Shohreh, Abtahi, Hamid, Satei, Parastu, Ghaznavi-Rad, Ehsanollah, Moslehi, Mohsen, Ganji, Ali·2021·Carbohydrate Polymers

Abstract

In this study, the electrospun poly(ε-caprolactone) (PCL)/Chitosan (CS)/curcumin (CUR) nanofiber was fabricated successfully with curcumin loaded chitosan nano-encapsulated particles (CURCSNPs). The morphology of the produced CURCSNPs, PCL, PCL/CS, PCL/CS/CUR, and PCL/CS/CUR electrosprayed with CURCSNPs were analyzed by scanning electron microscopy (SEM). The physicochemical properties and biological characteristics of fabricated nanofibers such as antibacterial, antioxidant, cell viability, and in vivo wound healing efficiency and histological assay were tested. The electrospraying of CURCSNPs on surface PCL/CS/CUR nanofiber resulted in the enhanced antibacterial, antioxidant, cell proliferation efficiencies and higher swelling and water vapor transition rates. In vivo examination and Histological analysis showed PCL/CS/CUR electrosprayed with CURCSNPs led to significant improvement of complete well-organized wound healing process in MRSA infected wounds. These results suggest that the application of PCL/CS/CUR electrosprayed with CURCSNPs as a wound dressing significantly facilitates wound healing with notable antibacterial, antioxidant, and cell proliferation properties.

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Crossref · 10.1016/j.carbpol.2021.117640

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Metadata

Authors
Fahimirad, S., Abtahi, H., Satei, P., Ghaznavi-Rad, E., Moslehi, M., & Ganji, A.
Venue
Carbohydrate Polymers
Publisher
Elsevier BV
Published
2021-05
Volume
259
Pages
117640
ISSN
0144-8617 (ISSN-L)
OpenAlex
W3124399199
Cited by
339
References
48
FWCI
13.00
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Wound healing performance of PCL/chitosan based electrospun nanofiber electrosprayed with curcumin loaded chitosan nanoparticles. https://app.cochat.ai/papers/10.1016/j.carbpol.2021.117640
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Fahimirad, S., Abtahi, H., Satei, P., Ghaznavi-Rad, E., Moslehi, M., & Ganji, A. (2021). Wound healing performance of PCL/chitosan based electrospun nanofiber electrosprayed with curcumin loaded chitosan nanoparticles. Carbohydrate Polymers. https://doi.org/10.1016/j.carbpol.2021.117640

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