Electrospun Medicated Nanofibers for Wound Healing: Review
Open accessAbstract
With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers’ attention as a simple and versatile manufacturing method. The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. This article first discusses the common types of wound dressing, and then summarizes the development of electrospun fiber preparation technology. Finally, the polymers and common biologically active substances used in electrospinning wound dressings are summarized, and portable electrospinning equipment is also discussed. Additionally, future research needs are put forward.
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By adjusting the concentration and viscosity of the solution, the voltage of the applied electric field, the distance between the receiving plate and the emission nozzle, and the shape and type of the collector, electrospinning fibers with different fiber diameters, fiber porosity, specific surface area, and spinning arrangements can be obtained.
“By adjusting the concentration and viscosity of the solution, the voltage of the applied electric field, the distance between the receiving plate and the emission nozzle, and the shape and type of the collector such as static or rotating, the electrospinning fibers with different fiber diameters, fiber porosity, specific surface area and spinning arrangements can be obtained [63, 72, 73].”
From Application of PLCL as a biodegradable polymer in biomedical engineering (2026) · cites this paper as [73]
Section 3.1 (page unavailable) says that adjusting solution viscosity, voltage and receiving distance changes nanofiber morphology and size. The Conclusions describe high porosity, high specific surface area and adjustable morphology, but the copy does not establish that changing collector shape or type, including static versus rotating collectors, produces the claimed differences in porosity, surface area or fiber arrangement. (LLM, conf=0.86)
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Application of PLCL as a biodegradable polymer in biomedical engineering
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- Authors
- Liu, X., Xu, H., Zhang, M., & Yu, D.-G.
- Affiliations
- University of Shanghai for Science and Technology (CN)
- Corresponding author
- Liu, Xinkuan
- Venue
- Membranes
- Publisher
- MDPI AG
- Published
- 2021-10-09
- Volume
- 11
- Issue
- 10
- Pages
- 770
- ISSN
- 2077-0375 (ISSN-L)
- PMC
- PMC8537333
- OpenAlex
- W3205480126
- Cited by
- 311
- References
- 159
- Citations by year
- 2026: 39 · 2025: 67 · 2024: 73 · 2023: 63 · 2022: 61 · 2021: 8
- FWCI
- 3.54
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Membranes (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Natural Science Foundation of Shanghai (No.20ZR1439000)
- Joint project of USST-CIHE (No. 20181116)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Keywords
- electrospun nanofibers, wound healing, wound dressings, electrospinning, drug delivery, antibacterial properties, extracellular matrix mimicry, bioactive materials
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