The DOI matches its Crossref record; 256 of the 256 references it cites were found in a registry or an index.
Hyaluronic acid in ocular drug delivery
Abstract
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues, hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry eye, vitreous substitutes and ophthalmic viscosurgical devices. Besides that, HA can be used as an effective drug carrier for ocular disease treatment due to its excellent biocompatibility, biodegradability, bioadhesion properties, viscoelasticity and receptor interaction characteristic. This review summarizes recent advances in HA-based drug delivery systems for ocular disease treatment in which it could be used as drug-polymer conjugate, drug carrier substrates, and surface modifications of the carrier. To achieve the optimum drug delivery efficacy under varied ophthalmic diseases, the molecular weight (MW) and amount of HA should be selected rationally and applied to design diverse delivery systems.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Additionally, HA has been shown to raise corneal adhesion and drug utilization due to its mucosal adhesion potential [95].”
From From design to Deployment: The innovative role of nanomicelles in targeted ophthalmic therapeutics (2025) · cites this paper as [95]
Citations
Cites
Understanding biophysicochemical interactions at the nano–bio interface
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., Klaessig, F., Castranova, V., & Thompson, M. (2009) · Nature Materials · doi:10.1038/nmat2442 · Cited by 7,083
CD44 is the principal cell surface receptor for hyaluronate
Aruffo, A. A., Stamenkovic, I., Melnick, M., Underhill, C. B., & Seed, B. (1990) · Cell · doi:10.1016/0092-8674(90)90694-a · Cited by 2,439
Hyaluronic Acid Hydrogels for Biomedical Applications
Burdick, J. A., & Prestwich, G. D. (2011) · Advanced Materials · doi:10.1002/adma.201003963 · Cited by 2,150
Gaudana, R., Ananthula, H. K., Parenky, A., & Mitra, A. K. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9183-3 · Cited by 1,406
Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
Zhao, F., Zhao, Y., Liu, Y., Chang, X., Chen, C., & Zhao, Y. (2011) · Small · doi:10.1002/smll.201100001 · Cited by 1,206
Binding of blood proteins to carbon nanotubes reduces cytotoxicity
Ge, C., Du, J., Zhao, L., Wang, L., Liu, Y., Li, D., Yang, Y., Zhou, R., Zhao, Y., Chai, Z., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105270108 · Cited by 938
The use of mucoadhesive polymers in ocular drug delivery
LUDWIG, A. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.07.005 · Cited by 925
Hyaluronic Acid in the Third Millennium
Fallacara, A., Baldini, E., Manfredini, S., & Vertuani, S. (2018) · Polymers · doi:10.3390/polym10070701 · Cited by 918
Hyaluronic acid—Based wound dressings: A review
Graça, M. F. P., Miguel, S. P., Cabral, . S. D., & Correia, I. J. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116364 · Cited by 843
Physicochemical Properties Determine Nanomaterial Cellular Uptake, Transport, and Fate
Zhu, M., Nie, G., Meng, H., Xia, T., Nel, A. E., & Zhao, Y. (2012) · Accounts of Chemical Research · doi:10.1021/ar300031y · Cited by 822
Research works printed but not linked: 1
- Rainer, 1996, Zusammenhange zwischen molekularen Parametern der Hyaluronsaure und der Viskoelastizitat der Synovia, Acta Medica Austriaca, 23, 133
Cited by
Sorted by citations
Items 101–196 of 196
Naik, S., Jain, N., Theruveethi, N., & Mutalik, S. (2025) · Scientific Reports · doi:10.1038/s41598-025-10960-9 · Cited by 8
Pandey, G., Kolipaka, T., Yadav, D., Methri, S. M., Singh, A. K., Natesan, S., & Srivastava, S. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.126781 · Cited by 8
Kaushal, N., Kumar, M., Tiwari, A., Tiwari, V., Sharma, K., Sharma, A., Marisetti, A. L., Gupta, M. M., Kazmi, I. A., Alzarea, S. I., et al. (2023) · Nanomedicine · doi:10.2217/nnm-2023-0123 · Cited by 8
Diress, M., Wagle, S. R., Lim, P., Foster, T., Kovačević, B., Ionescu, C. M., Mooranian, A., & Al‐Salami, H. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2431577 · Cited by 8
Advances of nanoparticles in transmucosal drug delivery
Zhang, L., Yang, C., Song, Y., Sheng, T., Li, J., Yu, J., Wu, X., & Ye, X. (2023) · Nano Research · doi:10.1007/s12274-023-6188-7 · Cited by 8
Li, M., Jin, M., & Yang, H.-Z. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130764 · Cited by 7
Hyaluronic Acid Gel as Middle Ear and External Auditory Canal Packing Material in Tympanoplasty
Faramarzi, M. R., Faramarzi, A., Roosta, S., Pishgar, S., & Owji, S. H. (2023) · Otolaryngology · doi:10.1002/ohn.554 · Cited by 7
Recent advances in polysaccharide-based strategies for glaucoma therapy: A review
Bui, H. L., Yang, C.-J., Huang, C.-J., & Lai, J. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.150433 · Cited by 7
A Review on Polymeric Nanostructured Micelles for the Ocular Inflammation-Main Emphasis on Uveitis
Kumar, M., Kaushal, N., Singh, A., Tiwari, A., Tiwari, V., & Pahwa, R. (2022) · Pharmaceutical Nanotechnology · doi:10.2174/2211738511666221019160908 · Cited by 7
Melnik, T., Porcello, A., Saucy, F., Delié, F., & Jordan, O. (2022) · Gels · doi:10.3390/gels8120776 · Cited by 7
From design to Deployment: The innovative role of nanomicelles in targeted ophthalmic therapeutics
Sun, M., Wang, J., Fan, W., Wang, K., Wang, Y., Zhang, J., Ding, S., Zhang, C., Feng, Z., Wang, Y.-G., et al. (2025) · Materials today. Bio · doi:10.1016/j.mtbio.2025.102537 · Cited by 7
“These microspheres demonstrated 73 % drug entrapment, 65 % mucin binding efficiency and controlled drug release over 8 h. Additionally, HA has been shown to raise corneal adhesion and drug utilization due to its mucosal adhesion potential [95].”
Applications and latest research progress of liposomes in the treatment of ocular diseases
Tang, H., Li, X., Jin, L., Dong, J., Li, Y., Li, C., Zhang, L., & Cheng, F. (2025) · Biointerphases · doi:10.1116/6.0004159 · Cited by 6
Wu, W., Li, R., Lv, C., Yang, D., Song, S., Yang, M. H., & Xiong, Y. (2025) · Biomaterials Research · doi:10.34133/bmr.0234 · Cited by 6
Guo, S., Wang, B., Mao, B., Zhang, T., Tang, X., Zhang, Q., Zhao, J., Chen, W., & Cui, S. (2025) · Biomacromolecules · doi:10.1021/acs.biomac.5c00935 · Cited by 6
Yetisgin, A. A., Durak, S., Kutlu, Ö., & Çetinel, S. (2024) · Macromolecular Bioscience · doi:10.1002/mabi.202300531 · Cited by 6
Hatamie, S., Shih, P., Chen, B., & Hatami, N. (2025) · Polymers for Advanced Technologies · doi:10.1002/pat.70094 · Cited by 7
Siddoway, A. C., White, B. M., Narasimhan, B., & Mallapragada, S. K. (2023) · Vaccines · doi:10.3390/vaccines11101572 · Cited by 6
Li, S., Zhao, Y., Chen, J., Wu, B., Wu, N., Sun, H., Chen, L., Feng, C., & Fu, Y. (2025) · Advanced Science · doi:10.1002/advs.202504732 · Cited by 5
Yang, X., Meng, J., Kang, Y., Shen, Y., & Zhu, R. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152139 · Cited by 5
Tian, W., Zang, L., Li, Y., Peng, C., Zhang, J., Shao, H., Xian, R., Sun, R. B., Liu, F., Tan, H., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124278 · Cited by 5
Shi, C., Chen, G., Wang, Y., Xia, Z., Zhong, M., Srivastava, S., Kumar, A., Wang, J., & Pan, Y. (2025) · European Polymer Journal · doi:10.1016/j.eurpolymj.2025.114409 · Cited by 6
Designing biomaterials for the treatment of autoimmune diseases
Tang, B., Xie, X., Lu, J., Huang, W., Yang, J., Tian, J., & Lei, L. (2024) · Applied Materials Today · doi:10.1016/j.apmt.2024.102278 · Cited by 5
Leonardi, F., Simonazzi, B., Martini, F. M., D’Angelo, P., Foresti, R., & Botti, M. (2024) · Veterinary Sciences · doi:10.3390/vetsci11080368 · Cited by 5
Alotaibi, W., Abusharha, A., Pearce, E. I., Althomali, M. M., Afsar, T., & Razak, S. (2024) · Clinical ophthalmology · doi:10.2147/opth.s493336 · Cited by 5
Nanotechnological approaches to improve corticosteroids ocular therapy
Formica, M. L., Scerbo, J. M. P., Alfonso, H. G. A., Palmieri, P. T., Ribotta, J., & Palma, S. D. (2024) · Methods · doi:10.1016/j.ymeth.2024.12.008 · Cited by 5
Lee, S., Jung, M.-Y., & Park, C. Y. (2025) · Drug Delivery · doi:10.1080/10717544.2025.2459775 · Cited by 5
Chitosan‐Based Smart Hydrogel Platform for Targeted Intravesical Delivery in Bladder Cancer Therapy
Tian, H., & Yang, L. (2025) · Journal of Polymer Science · doi:10.1002/pol.20241113 · Cited by 5
Bebawy, G., Sanderson, J., & Qi, S. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126323 · Cited by 5
Mishra, A., Halder, J., Saha, I., Rai, V. K., Mahanty, R., Pradhan, D., Dash, P., Das, C., Rajwar, T. K., Satpathy, B., et al. (2025) · AAPS PharmSciTech · doi:10.1208/s12249-025-03090-y · Cited by 5
The effect of molecular weight of hyaluronic acid on corneal cell viability
Park, J.-H., & Park, C. Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-21960-0 · Cited by 4
Kamenická, B., Rajs, P., Veith, M., & Klusoň, P. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.151509 · Cited by 4
Chaidaroon, W., Pantarote, S., Upaphong, P., & Choovuthayakorn, J. (2022) · Clinical ophthalmology · doi:10.2147/opth.s388276 · Cited by 4
Ding, Y., Jia, Q., Su, Z., Chen, H., Ye, J., Xie, D., Wu, Y., He, H., Peng, Y., & Ni, Y. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101243 · Cited by 4
Grego, A. L., Fankhauser, A. D., Behan, E. K., Atzet, S. K., Haeussler, D. J., Mello, F. R., Bortolini, M., & Montiani‐Ferreira, F. (2024) · Veterinary Research Communications · doi:10.1007/s11259-024-10559-x · Cited by 4
Ponzin, D., Fasolo, A., Montani, G., & Bazzocchi, D. (2025) · Ophthalmology and Therapy · doi:10.1007/s40123-025-01195-y · Cited by 3
Zhang, S., Song, M., Zhang, J., Bai, J., Cao, X., Zhu, L., & Tian, R. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103965 · Cited by 3
Kasarinaite, A., Ou, J., Chen, K., Peng, D., Jia, W., Ding, C., Huang, W., Hay, D. C., & Chen, Y. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.12.034 · Cited by 3
Molecular weight of hyaluronic acid in nanocarriers
Zhu, Q., Cheng, H., & Guan, J. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125242 · Cited by 3
The progress of hyaluronic acid’s application in therapeutic delivery
Laffleur, F., Bachleitner, K., Millotti, G., Lagast, J., Veider, F., & Bernkop‐Schnürch, A. (2025) · Therapeutic Delivery · doi:10.1080/20415990.2025.2483150 · Cited by 3
Chemically modified hyaluronic acid derivatives as ocular drug carriers: A review
Sen, O., De, S., Dey, G., Das, S., Bhowmik, M., Jana, S., Nandi, G., & Manna, S. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.145049 · Cited by 3
del Olmo, J. A., Melero, A., Pino, A., de Cestafe, N. M., Gartziandia, O., de Heredia, M. U. L., Torrecilla, J., Gómez, L. M. M., Cid, S. B., Alonso, J. M., et al. (2025) · Journal of Pharmaceutical and BioTech Industry · doi:10.3390/jpbi2040016 · Cited by 3
Hyaluronic Acid in Drug Delivery
Maghsoudnia, N., Eftekhari, R. B., Roshandel, M., Ahmadi, M., Edalat, M., Hajimolaali, M., Milani, S., Shal, M. K., & Dorkoosh, F. A. (2022) · Royal Society of Chemistry eBooks · doi:10.1039/9781839166235-00126 · Cited by 3
Ouyang, X., Yu, W. W., Wang, J., Wang, H., Wang, S., Wang, G., Sun, B., Xu, C., Liu, Y., Wang, W., et al. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.112075 · Cited by 3
Ren, P., Yang, C., Xing, R., & Yan, X. (2024) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2024.133719 · Cited by 3
Ouyang, X.-W., Yi, Y.-M., Zou, S.-P., Hu, Q.-Y., Huang, Z., Li, Q.-X., & Luo, J.-Y. (2024) · International Journal of Ophthalmology · doi:10.18240/ijo.2024.06.17 · Cited by 3
He, K., Hu, Y., Bai, X., & Liao, X. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137369 · Cited by 3
Zhang, M., Shi, D., Cui, M.-M., Li, J., Cheng, W., Pu, C., Zhang, J., & Wang, C. (2025) · Archives of Microbiology · doi:10.1007/s00203-025-04274-7 · Cited by 4
Recent Advancement in Ocular Drug Delivery System: A Systematic Review
Mittal, C., Amle, V. S., Kumar, R., Sood, P., Uniyal, A., & Singh, H. (2023) · Journal for Research in Applied Sciences and Biotechnology · doi:10.55544/jrasb.2.3.32 · Cited by 3
Zhang, M., Wang, Y., Wang, J., Zuo, J., Jiang, F., & Cao, F. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114574 · Cited by 2
Singh, M., Devi, M., Kumar, P., Monika, Singh, R., & Jhawat, V. (2026) · International Ophthalmology · doi:10.1007/s10792-026-03931-0 · Cited by 2
Abdel‐Bar, H. M., Elkashlan, A. M., Madkour, A. B., Abdallah, M. S., Hamdi, M., & Ali, I. H. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.151577 · Cited by 2
Li, D., Ling, Y., Cai, Y., Jiang, H., & Liu, H. (2026) · Journal of Polymer Science · doi:10.1002/pol.20250869 · Cited by 2
Hu, B., Wang, H., Ji, C., Xu, X., Wang, L., Cao, T., Gao, M., Zhao, Y., Wang, B., Xuan, W., et al. (2026) · Biomaterials Science · doi:10.1039/d5bm01898f · Cited by 2
Mazidi, Z., Garshasbi, H. R., Naghib, S. M., Heydari, M. Z., & Mozafari, M. R. (2024) · Mini-Reviews in Organic Chemistry · doi:10.2174/0118756298304506240628062045 · Cited by 2
Enhanced Corneal Repair with Hyaluronic Acid/Proanthocyanidins Nanoparticles
Liu, Y., Ge, X., Wu, X., & Guan, L. (2025) · ACS Omega · doi:10.1021/acsomega.4c09159 · Cited by 2
Complex viscosity of polyhyaluronic acid
Pulatsu, E., Kanso, M. A., Chakraborty, R., & Giacomin, A. J. (2025) · Physics of Fluids · doi:10.1063/5.0259252 · Cited by 2
Stančiauskaitė, M., Marksa, M., Іванаускас, Л., & Ramanauskienė, K. (2022) · Antioxidants · doi:10.3390/antiox11091771 · Cited by 2
Pankoh, T., Itthipanichpong, R., & Ratanavaraporn, J. (2023) · Biomedical Engineering International Conference · doi:10.1109/bmeicon60347.2023.10322033 · Cited by 1
Application of hyaluronic acid: Therapeutics, pharmaceuticals, and cosmetics
Bisht, P., Kumbhar, A. P., Ranjan, O. P., Sinha, M. K., Kovela, R. K., Vaishali, K., & Kumar, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-14042-6.00006-3 · Cited by 1
Tailoring the Composition of HA/PEG Mixed Nano-Assemblies for Anticancer Drug Delivery
Zurletti, B., Andreana, I., Salaroglio, I. C., Bincoletto, V., Manzoli, M., Rolando, B., Milla, P., Riganti, C., Stella, B., & Arpicco, S. (2025) · Molecules · doi:10.3390/molecules30061349 · Cited by 1
McLain, A., Saffie-Siebert, S. R., Nielsen, N. S., Patterson, B., Scavenius, C., Enghild, J. J., Marshall, J., Rachwalska, P., Welsh, M., Sutera, F. M., et al. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114315 · Cited by 1
Popova, E. V., Tikhomirova, V. E., Taliansky, M. E., & Kost, O. A. (2025) · Russian Chemical Bulletin · doi:10.1007/s11172-025-4777-1 · Cited by 1
Wang, H., Wang, Q., Wang, J., Wang, K., Wang, J., Zhang, X., Chen, H., Chen, X., Liu, Y., Xiao, J., et al. (2025) · Friction · doi:10.26599/frict.2025.9441189 · Cited by 2
Wang, Y., Duan, J., Zang, L., Sun, T., Lv, H., Liu, F., & Ma, X. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1772172 · Cited by 1
Yang, Y., Jun-mei, S., Wang, T., Wu, S.-W., Zhou, Y., Gu, Z., Ling-hong, G., & Jiang, X. L. (2026) · Chinese Journal of Polymer Science · doi:10.1007/s10118-026-3657-y · Cited by 1
Natural Polymers for Drugs Delivery
Manjit, M., & Mishra, B. (2023) · Springer eBooks · doi:10.1007/978-981-19-7656-8_2 · Cited by 1
Transdermal Permeation Enhancing Potentials of Natural Products
Kankane, R., Maurya, S. K., & Patil, U. K. (2024) · Drug Delivery Letters · doi:10.2174/0122103031307565240806112110 · Cited by 1
Natural polymers for specialized formulations
Kaity, S., Sah, S. K., Hussain, N., & Ramesh, G. S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95367-2.00004-1 · Cited by 1
Effects of Ginsenoside Rb1 Loaded Films on Oral Wound Healing
Lee, J. H., Park, S. H., Mohammed, A. N., Lee, M., Kweon, D., Chae, Y. K., Lee, K.-E., Kim, M. S., Lee, H., Choi, S. C., et al. (2022) · THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY · doi:10.5933/jkapd.2022.49.3.300 · Cited by 1
Plant polysaccharides for nasal drug delivery
Necolau, M. I., Pandele, A. M., & Voicu, Ș. I. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90780-4.00008-5
Ikeora, O. C., Joseph, S. S., & Zeinalipour‐Yazdi, C. D. (2023) · Research Square · doi:10.21203/rs.3.rs-2743668/v1
Li, J., Lu, Y., Kang, W., Yu, Y., Shi, P., He, M., & Wang, Y. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4529039
Ma, L., Fang, X., Wang, P., Chen, M., Li, M., Yang, Y., & Wang, C. (2024) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2024.134367
Hu, J., Shen, W., Yan, P., Ge, X., Wu, S., Mao, Y., Ao, F., Jia, X., & Wang, Y. (2025) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2025.2525672
Narwal, S., Dushyant, Singh, G., Grewal, N., Chanalia, V., & Dhingra, A. K. (2025) · Current Drug Metabolism · doi:10.2174/0113892002384586250731104453
In Vitro Study of the Effect of 1.0% Sodium Hyaluronate on Bacterial Strains and Antibiotics
Tüzemen, N. Ü., Sarı, E. S., Topaç, T., Efe, K., Özkaya, G., Özakın, C., & Baykara, M. (2025) · Uludağ Üniversitesi Tıp Fakültesi Dergisi · doi:10.32708/uutfd.1641884
Cao, P., Cheng, Y., Li, Z., Cheng, Y.-J., Chu, X., Geng, C., Yin, X., & Li, Y. (2023) · Figshare · doi:10.6084/m9.figshare.22608448
Cao, P., Cheng, Y., Li, Z., Cheng, Y.-J., Chu, X., Geng, C., Yin, X., & Li, Y. (2023) · Figshare · doi:10.6084/m9.figshare.22608445
Cao, P., Cheng, Y., Li, Z., Cheng, Y.-J., Chu, X., Geng, C., Yin, X., & Li, Y. (2023) · Figshare · doi:10.6084/m9.figshare.22608451
Cao, P., Cheng, Y., Li, Z., Cheng, Y.-J., Chu, X., Geng, C., Yin, X., & Li, Y. (2023) · Figshare · doi:10.6084/m9.figshare.22608457
Additional file 1 of OCTN2- and ATB0,+-targeted nanoemulsions for improving ocular drug delivery
Tang, B., Wang, Q., Zhang, G., Zhang, A., Zhu, L., Zhao, R., Gu, H., Meng, J., Zhang, J., & Fang, G. (2024) · Figshare · doi:10.6084/m9.figshare.25485833
Cao, P., Cheng, Y., Li, Z., Cheng, Y.-J., Chu, X., Geng, C., Yin, X., & Li, Y. (2023) · Figshare · doi:10.6084/m9.figshare.22608454
Marine materials: New hope for biomedical applications
Li, Y., Liao, J., Li, S., Xiao, Z., Gao, Z., Fan, J., Wang, Y., Wang, T., Zhang, Q., Zhang, C., et al. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2026.100370 · Cited by 2
Liu, L., Li, D., Wang, G., Yu, J., Wan, J., He, D., Li, Y., Ma, J., Tang, H. R., & Wang, L. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.151777
Falcone, G., Formica, M. L., Alfonso, H. G. A., Ribotta, J., Tártara, L. I., Amante, C., Aquino, R. P., Gaudio, P. D., Palma, S. D., & Russo, P. (2026) · International Journal of Pharmaceutics X · doi:10.1016/j.ijpx.2026.100547
Hyaluronic acid-modified PLGA nanoparticles for enhanced ocular drug delivery
Huang, S., Tang, T., He, H., Li, F., Su, B., Li, S., Ban, J., Jia, H., & Chen, H. (2026) · Journal of Microencapsulation · doi:10.1080/02652048.2026.2669806
Ahmadian, Z., & Kaji, H. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119791
Yang, F., Wang, M., Geng, C., Zhang, X., Lv, Z., Yang, K., Xu, G., & Wang, S. (2026) · Biomacromolecules · doi:10.1021/acs.biomac.5c02632
Hyaluronic acid nanoparticle as drug delivery carrier for the treatment of allergic conjunctivitis
Lin, C.-W., Hu, W.-P., & Su, W. (2026) · Bio-Medical Materials and Engineering · doi:10.1177/09592989261474686
Çırak, R., Aytekin, E., Polat, H. K., Kaplan, O., Çelebi̇er, M., & Pehlivan, S. B. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18091068
Liu, S., Sun, P., Liu, X., Tan, J., Gong, Y., Chen, J., Xu, Q., Huang, Y., Yang, F., Wang, X., et al. (2026) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2026.101190
Lin, Z., Cheng, M., Cui, H., CHEN, Y., Jiang, K., Zhu, L., Xu, C., Hong, J., & Zhang, C. (2026) · Biomaterials Science · doi:10.1039/d6bm00870d
Ni, P., Duan, D., Deng, M., Zhong, M., Zhong, C., Zhao, Y., Yuan, T., & Yuan, T. (2026) · Journal of Materials Chemistry B · doi:10.1039/d6tb01458e
Zhong, Q., & Kennett, K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44037-3.00147-0
Wu, Y., Li, M., Le, X., Chen, T., & Gong, Y. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.71883
Metadata
- Authors
- Zhang, X., Wei, D., Xu, Y., & Zhu, Q.
- Affiliations
- Nantong University (CN)
- Corresponding author
- Zhu, Qiang
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2021-07
- Volume
- 264
- Pages
- 118006
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W3151813161
- Cited by
- 196
- References
- 256
- Citations by year
- 2026: 26 · 2025: 41 · 2024: 50 · 2023: 49 · 2022: 22 · 2021: 8
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Carbohydrate Polymers (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Natural Science Foundation of Jiangsu Province (BK20190922)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Health Sciences › Medicine › Ophthalmology › Ocular Surface and Contact Lens
- Keywords
- hyaluronic acid, ocular drug delivery, drug carriers, polymer-drug conjugates, ophthalmic viscosurgical devices, vitreous substitutes, dry eye, bioadhesion, molecular weight, surface modification, biodegradable polymers, receptor targeting
- MeSH terms
- Animals, Drug Carriers, Eye Diseases, Humans, Hyaluronic Acid, Micelles, Polymers, Dry Eye Syndromes, Drug Delivery Systems, Immunoconjugates, Hydrogels, Nanoparticles, Administration, Ophthalmic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
