Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
Huang, Huocong, Wang, Zhaoning, Zhang, Yuqing, Pradhan, Rachana N., Ganguly, Debolina, Chandra, Raghav, Murimwa, Gilbert, Wright, Steven, Gu, Xiaowu, Maddipati, Ravikanth, Müller, Sören, Turley, Shannon J., Brekken, Rolf A.·2022·Cancer Cell
Cited by (540)
Items 501–540 of 540
- Immunotherapy in pancreatic cancer: overcoming the challenges of tumor heterogeneityMari Nakamura, Zunyu He, Ronit Dhulia, Gulam Abbas Manji, Tannishtha Reya · 2026 · Trends Open
- Nanomaterials targeting cancer-associated fibroblasts to overcome stromal barriers in cancer immunotherapyZhongsong Zhang, Wang Rong, L Chen · 2026 · Journal of Nanobiotechnology
- CA19-9 induces microenvironment remodeling in pancreatic ductal adenocarcinomaJasper Hsu, Hyemin Song, Satoshi Ogawa, Casie S. Kubota, Kristina L. Peck, Emily Jacobs, Lizmarie Garcia-Rivera, Jonathan Zhu, Yuan Sui, Woncheol Jung et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Bidirectional crosstalk between cancer-associated fibroblasts and tumor immunity: shaping the microenvironment and response to immune checkpoint therapyS Q Wang, Di Wang, Y-N Zhou, Wen Li, Guofu Sun, Lijuan Cao, Chao Feng, Yongjing Chen, Changshun Shao, Qi Gui et al. · 2026 · Experimental Hematology and Oncology
- Genomic landscape and tumor immune microenvironment of osteosarcoma: Bridging mechanistic insights to precision therapeuticsChenchen Yang, Yiyang Yu, Yaqi Wang, Zhenyu Cai, Yuwei Zhao, Hengyue Ma, Jie Xu, Huaiqiu Zhu, Tingting Ren, Xiaodong Tang et al. · 2026 · Bone Reports
- HLA‐DR + Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell CarcinomaXiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lin Zhang, Y Yiannian He · 2026 · Advanced Science
- The Dual Roles of Regulatory B Cells in Infection, Cancer, and ImmunityAnni Feng, Qi Li, Ning Jiang, Qijun Chen · 2026 · MedComm
- Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially regulate T-cell phenotype and functionSaumya Y. Maru, Meredith Wetzel, Jacob T. Mitchell, Nicole Groß, Lalitya Andaloori, Kathryn L. Howe, Emma Kartalia, Guanglan Mo, James Leatherman, Won Jin Ho et al. · 2026 · The Journal of Immunology
- CAF-derived PAI-1 serves as an EGFR ligand and fuels KRAS-mutant pancreatic cancerYu Wang, C Liu, Song Gao, Bo Wang, Hongwei Wang, Zijian Shi, Shunjin Xia, Jiayong Li, Xiaofeng Yao, Xiaofan Guo et al. · 2026 · Nature Communications
- Spatial transcriptome profiling links SERPINA3 to nerve-associated immunosuppression in pancreatic cancerB A Liu, Yanrong Yang, Y P Zhang, Chenglin Xin, T Zhang, Lehan Pan, Zhongtao Zhang, 杨盈赤, Wei Guo, Dan Tian · 2026 · Biochemical and Biophysical Research Communications
- Characterization of cancer-associated fibroblast populations that promote tertiary lymphoid structure formation in murine melanoma tumorsRobert Barnes, Kara L. Cummings, Mirna Perusina Lanfranca, Anthony B. Rodriguez, Katarzyna Stasiak, Burkhard Ludewig, Sepideh Dolatshahi, Víctor H. Engelhard · 2026 · Frontiers in Immunology
- P4HA1⁺ collagen-modifying fibroblasts are associated with pro-tumor niches and therapeutic vulnerabilities in colorectal cancerKai Gui, Yuehua Chen, Qinqin Du, Ke Lv, W Y Wang, Ziyun Li, Yuhang Cheng, Wenyan Wu, Min Tang, Cheng Zhang et al. · 2026 · Journal of Translational Medicine
- Treg-derived exosomal miR-146a orchestrates bidirectional Treg-CAF crosstalk to sustain immunosuppressive tumor microenvironmentsHaicheng Ma, Yingying Zheng, Mengmeng Pei, Yanyan Zeng, Z J Zhang, Yanyan Xu, Xueting Wang, Wei Zhang, Niannian Li, Shaoqiang Wang · 2026 · Medical Oncology
- Pancreas-specific lipid nanoparticle-mediated interleukin-10 mRNA delivery ameliorates acute pancreatitisYuqin Men, Zhi Cao, David O. Popoola, Li Chen, Yong Teng, Yamin Li · 2026 · Journal of Materials Chemistry B
- Cancer-associated mesothelial cells drive immune escape and therapy resistance in ovarian cancerMaeva Y. Chauvin, Julien Roche-Prellezo, Virginie Lafont, Henri‐Alexandre Michaud, Estelle Tromelin, Robin Michel, Clara Freixinos, Marie-Charlotte Meinsohn, Pierre‐Emmanuel Colombo, Nathalie Bonnefoy et al. · 2026 · Journal for ImmunoTherapy of Cancer
- Amino acid metabolic regulatory network in tumor immune escape: mechanistic exploration and intervention directionsZhaoxia Liu, Lin He, Yu Tian, Shipin Feng, Xiongtao Yang, Hui Wu, Qiaoshuang Pu, Yan Wang, Xiaoli Yuan · 2026 · Frontiers in Immunology
- The tumor microenvironment in pancreatic cancer: from composition to therapeutic targetingBeatriz Magalhães Gomes, Pedro Luiz Porfírio Xavier · 2026 · Biochemical Society Transactions
- Drug resistance in cancer radiotherapy: From mechanisms to overcoming strategiesYang Chen, Chao‐Yun Cai, Xiao-Chen Xu, Zheng Yang, Jia Li, Qingming Pan, Lei Wang, Wei Luo, Zhe‐Sheng Chen, Leli Zeng et al. · 2026 · Pharmacological Research
- The MAPK pathway as a pharmacological target to reprogram cancer-associated fibroblasts and disrupt the stromal shieldMasaki Arioka, Fumi Takahashi‐Yanaga · 2026 · Biochemical Pharmacology
- Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8 + T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic AdenocarcinomaKaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, 戴樂為, Yuwei Qi, Ruqian Chen, Ying Xu, Hangbin Li et al. · 2026 · Advanced Science
- From Pixels to Stroma: AI-Driven Spatial Profiling of Cancer-Associated Fibroblasts on H&E and Its Implications for ImmunotherapyTarun Dalani, Wong Kwun Hin Jerry, Jialin Wu, Xin Fang, Tiejun Feng, Fuda Xie, Muyang Huang, Yuanke Liang, Ka Fai To, Wei Kang et al. · 2026 · Cancers
- The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategiesguoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu · 2026 · Advanced Science
- Single‐Cell Transcriptome of Anaplastic Thyroid Cancer Reveals Immunosuppressive Tumor Microenvironment RemodelingSaeko Tahara, Akiko Iguchi‐Manaka, Naoto Takeuchi, Tomohei Matsuo, Akira Shibuya, Kazuko Shibuya, Haruka Ozaki · 2026 · Cancer Medicine
- TGF-β- and IL-1-dependent fibroblast states differentially shape pancreatic cancer microenvironments and metastasisPriscilla S.W. Cheng, Eloise G. Lloyd, Muntadher Jihad, Marta Zaccaria, Kristen Burgess, Gianluca Mucciolo, Sneha Harish, Weike Luo, Judhell S. Manansala, Wenlong Li et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- A Full Spectrum Fibroblast Profiling Panel Reveals Phenotypic and Metabolic Heterogeneity of Cancer-Associated Fibroblasts at the Single-Cell LevelKevin Muñoz Forti, Marta R. Storl-Desmond, Sayana Issac, Daniel Martínez, Michał Nizio, Shan C Lin, Ani Solanki, Simon Schwörer · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Lineage tracing for deciphering tumor evolution and immune microenvironmentZhong Liang, Chen Yue, Chen-Yu Jiang, Zhou Guang-ding, Dan He, Ming Liu · 2026 · Trends Open
- Engineering strategies to address immune and delivery barriers in pancreatic ductal adenocarcinoma: a barrier-matched translational frameworkYang Li, Yu Li, Jia Fan, Zhi-qiang San, Junfeng Ye · 2026 · Frontiers in Immunology
- Cellular crosstalk of fibroblast–myofibroblast transition in intestinal homeostasis and diseaseHaodong Yuan, Lin Zhao, Peiqi Xu, Yu Sun, Kai Yin, Shengjun Wang · 2026 · Biomarker Research
- Non-immune regulation of tertiary lymphoid structures in cancerOwen K. Challen, Evelyn Fitzsimons, Wyatt W. Anderson, Daniella Liao, Willie Wu, Vanessa G. P. Souza, Katya Benard, Julia R. Naso, Spencer D. Martin, Wan L. Lam et al. · 2026 · Frontiers in Immunology
- Targeting cancer-associated fibroblasts: therapeutic strategies, translational challenges, and future perspectivesYanping Jiang, Bo Ding, Han Yin, Yue Hua, Ning Ma, Pengcheng Hu, Jianbin Deng, Fu-Gen Wu, Yang Shen · 2026 · Journal of Hematology & Oncology
- From CAF subtypes to clinically relevant states: cancer-associated fibroblasts in pancreatic ductal adenocarcinomaYi Hao, Yi Wang, Qinyang Du, Gaopeng Li · 2026 · Frontiers in Immunology
- The impact of the tumor microenvironment on immune checkpoint inhibitor resistance in prostate cancer: Mechanistic insights and therapeutic strategiesSiyu Zhou, Yifan Bi, Ziyi Xiong, Yang Guo, Xiaolu Cui, Mo Zhang · 2026 · Critical Reviews in Oncology/Hematology
- Metabolic reprogramming in cancer-associated fibroblasts: orchestrating the tumor immune microenvironment and response to immune checkpoint blockadeLuoman Gan, Zhonglong Liu, Liren Cao, Xiaoyan Meng, Xuanhao Liu, Xu Wang, Yue He · 2026 · Experimental Hematology and Oncology
- Cancer-Associated Fibroblasts in Perineural Invasion: Biological Roles and Therapeutic StrategiesXinxing Cui, Yun He, Yang Liu, Aiping Lu, Fangfei Li · 2026 · Cells
- Evaluating cytokine-based therapeutics in human 3D in vitro immune-containing assembloidsNina Maenhoudt, Mechthild Lütge, Melanie Obenloch, Aljona Caironi, Maria Kiratzis, Pol Jean-Mairet, SAMUELE GRAZIANO, Philipp Fröbel, Tamara Hüsser, Emilio Yángüez et al. · 2026 · Frontiers in Cell and Developmental Biology
- Cytokine context shapes antigen-presenting and matrix-producing states of cancer-associated fibroblastsFeifei Song, Qi Chen, Dengfeng Huang, Youhua Zhang, Dongyan Han, Wei Rao, Man Li, Yaohui Gao, Renfeng Zhang, Huiyuan Zhu et al. · 2026 · Signal Transduction and Targeted Therapy
- Dynamic Expression Quantitative Trait Locus Mendelian Randomization in Activated CD4‐Positive T Cells Nominates SMDT1 and CMTM7 as Candidate Genes in Pancreatic CancerHaitao Wang, Bingbing Wang, Xiaoman Duan, Guangtao Jiao, Meng Chen, Xin Guan, Juncheng Cao, Luying Cui, Hengzhen Li, Zhiwei Li · 2026 · Molecular Carcinogenesis
- Dataset related to article "Depicting the cellular complexity of pancreatic adenocarcinoma by Imaging Mass Cytometry: focus on cancer-associated fibroblasts"Marco Erreni, Maria Rita Fumagalli, Raffaella D’Anna, Mauro Sollai, Silvia Bozzarelli, Gennaro Nappo, Damiano Zanini, Raffaella Parente, Cecília Garlanda, Lorenza Rimassa et al. · 2025 · Zenodo (CERN European Organization for Nuclear Research)
- Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis_Spatial H&E imagesSeongryong Kim, Leem Galam, Junjeong Choi, Jong-Eun Park, Chang Moo Kang, Seungmin Bang · 2024 · Zenodo (CERN European Organization for Nuclear Research)
- Cancer-associated fibroblasts: origins, functional heterogeneity and therapeutic potentialLiting Zhou, Mengyue Tang, Keke Wang, Nan Wang, Jiachen Zhang, Kangdong Liu, Xiang Li, Zigang Dong · 2026 · Signal Transduction and Targeted Therapy