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Cited by 16Respiratory Support and MechanismsNeonatal Respiratory Health ResearchNosocomial Infections in ICU

Mechanical Ventilation and Acute Respiratory Distress Syndrome in Older Patients

Siner, Jonathan M., Pisani, Margaret A.·2007·Clinics in Chest Medicine
DOI 10.1016/j.ccm.2007.08.008
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Abstract

As the population of the United States ages, an increasing number of elderly adults will be cared for in intensive care units. An understanding of how aging affects the respiratory system is important for patient care and ongoing research. The incidence rates of acute respiratory failure and of acute respiratory distress syndrome increase dramatically with age, and therefore understanding the relationship between age and ARDS is important. This article focuses on the age-specific changes in respiratory function. We present a discussion of the management of acute lung injury and acute respiratory distress syndrome with a focus on the role of mechanical ventilation. We conclude with what is known about age and its impact on mortality and functional outcomes after mechanical ventilation.

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Crossref · 10.1016/j.ccm.2007.08.008

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  • Patients with severe sepsis and septic shock often require mechanical ventilation, which in the elderly is independently associated with increased mortality.

    “Patients with severe sepsis and septic shock often require mechanical ventilation, which in the elderly is independently associated with increased mortality (146, 147).”

    From Aging and Lung Disease (2020) · cites this paper as [147]

  • Elderly patients exhibit reduced tolerance to systemic inflammation, with increased mortality when compared with younger septic individuals.

    “Further, elderly patients exhibit reduced tolerance to systemic inflammation, with increased mortality when compared with younger septic individuals (146–148).”

    From Aging and Lung Disease (2020) · cites this paper as [147]

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Authors
Siner, J. M., & Pisani, M. A.
Affiliations
Yale University (US)
Corresponding author
Siner, Jonathan M.
ORCID
Pisani, Margaret A.
Venue
Clinics in Chest Medicine
Publisher
Elsevier BV
Published
2007-12
Volume
28
Issue
4
Pages
783-791
ISSN
0272-5231 (ISSN-L)
DOI
10.1016/j.ccm.2007.08.008
OpenAlex
W2030444885
Cited by
16
References
67
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2021: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2012: 2
FWCI
0.05
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Clinics in Chest Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
Keywords
mechanical ventilation, acute respiratory distress syndrome, acute lung injury, elderly patients, acute respiratory failure, ARDS mortality, functional outcome, intensive care unit
MeSH terms
Aged, Humans, Respiration, Artificial, Respiratory Distress Syndrome, Survival Rate, Treatment Outcome

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