A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

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Items 801–900 of 930

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3. PARPis and Other Novel, Targeted Therapeutics in Pancreatic Adenocarcinoma
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4. BRCA1 and DNA damage response
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5. Reversion from basal histone H4 hypoacetylation at the replication fork increases DNA damage in FANCA deficient cells
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6. Special section: Replication stress, a threat to the nuclear and mitochondrial genome
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7. Small‐molecule Effectors of DNA Repair Proteins: Applications for Development of Cancer Therapeutics and Research
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8. Faculty Opinions recommendation of A dominant mutation in human RAD51 reveals its function in DNA interstrand crosslink repair independent of homologous recombination.
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9. Data from The Mechanisms of Action of Tumor Treating Fields
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10. Data mining and function analysis of a key ferroptosis target FANCD2 positively correlated with PD-L1 expression
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11. PRIMPOL promotes replication fork progression but not double strand break formation in FBH1-deficient cells in response to hydroxyurea
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12. Distinct complexes of RAD51 paralogs participate in different fork protection pathways
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13. BRCA1 promotes homologous recombination through separable DNA and RAD51 binding activities within its disordered region
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14. Implications of BRCA1 mutations in basal-like breast cancer development and treatment
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15. Further Insights Into the Regulation of the Fanconi Anemia FANCD2 Protein
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16. Overcoming Innate and Acquired Therapy Resistance by Targeting DNA Repair in Human Cancer Cells
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17. DNA Damage Signalling in BRCA1-Deficient Mammary Progenitor Cells Activates Autologous p52/RelB NF-κB
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18. Bedeutung der Expression von RAD51 für die Reparatur von DNA-Schäden mittels Homologer Rekombination in humanen Tumorzelllinien
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19. The phosphatase MKP1 as a target to enhance replicative stress and apoptosis in tumor cells
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20. The Ras effector NORE1A forms a tumor suppressor complex with BRCA1.
    Nicholas C Nelson · 2015 · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville)
21. Signaling of DNA Replication Stress Through the ATR Checkpoint
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22. ATRX Protects Cells Against Replication-Induced Genomic Instability
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23. The regulation of DNA damage signalling and repair by MOB2
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24. Uncovering the secrets of protein interactions with the DNA enforcing genomic stability
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25. Insights Into Chromatin Modification and FANCD2 Phosphorylation in DNA Damage Repair
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26. The Role of Fanconi Anemia Proteins in DNA Repair, Replication Stress and Genome Stability
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27. Control of DNA Replication by ATR
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28. Técnicas de análise genômica permitem estabelecer o diagnóstico etiológico de crianças com baixa estatura de causa desconhecida
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29. WITHDRAWN: Beyond interstrand crosslinks repair: Contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA
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30. Mechanism of replication fork reversal and protection by human RAD51 and RAD51 paralogs
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31. Natural and Synthetic Strategies for DNA Maintenance and Recording
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32. Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity
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33. The evolving role of PARP inhibitors in advanced ovarian cancer
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34. Investigating molecular targets of the DNA damage response in triple negative breast cancer
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35. Beyond the Fanconi anemia pathway: new mechanisms of DNA interstrand crosslink repair
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36. Faculty Opinions recommendation of DCAF14 promotes stalled fork stability to maintain genome integrity.
    Mirit I. Aladjem, Haiqing Fu · 2021 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
37. TRANSCRIPTIONAL REGULATION OF SOX5 AND WWOX BY FANCD2
    Kathryn A. Henrikson · 2021
38. Faculty Opinions recommendation of Non-enzymatic roles of human RAD51 at stalled replication forks.
    Nei‐Li Chan, Peter Chi · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
39. Mechanism of Replication Fork Reversal and Protection by Human RAD51 and RAD51 Paralogs
    Swagata Halder, Aurore Sanchez, Lepakshi Ranjha, Angelo Taglialatela, Giordano Reginato, Ilaria Ceppi, Ananya Acharya, Roopesh Anand, Alberto Ciccia, Petr Ćejka · 2020 · SSRN Electronic Journal
40. Faculty Opinions recommendation of Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors.
    Antony M. Carr · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
41. Faculty Opinions recommendation of BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
    Luca Pellegrini · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
42. Faculty Opinions recommendation of BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
    John A. Tainer · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
43. Faculty Opinions recommendation of Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication.
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44. Causes and consequences of mitotic DNA damage
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45. Conserved and Divergent Features of DNA Repair
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46. The BRCA1 isoform, BRCA1-IRIS, operates independently of the full-length BRCA1 in the Fanconi anemia pathway
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47. Chromatin regulators in DNA replication and genome stability maintenance during S-phase
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48. Data from A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
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49. Data from The Mechanisms of Action of Tumor Treating Fields
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50. Author response: Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells
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51. Editor's evaluation: Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells
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52. Mitotic processing of DNA replication and repair intermediates in cancer
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53. DNA Replication Stress and Genome Instability in Breast Cancer
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54. SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells
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55. Oncogenic STIL-mediated loss of BRCA1 functionality causes DNA damage and centrosome amplification
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56. Additional file 9 of FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells
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57. Dual roles of UFMylation on stalling fork stability
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58. Repair Mechanisms and Initiation in Carcinogenesis
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63. Polymerase Eta Recruits FANCD2 to Common Fragile Sites to Maintain Genome Stability
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66. DNA damage response in cancer: New treatment strategies
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74. The bacterial MRE11 – RAD50 and DNA2 – WRN homologs process replication forks at distinct and separate loci on the chromosome
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100. DNA damage-induced nuclear envelope rupture : A new cancer vulnerability
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