Jasin, Maria

Brca1 Controls Homology-Directed DNA Repair

Moynahan, M. E., Chiu, J. W., Koller, B. H., & Jasin, M. (1999) · Molecular Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 1,245

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2

Schlacher, K., Wu, H., & Jasin, M. (2012) · Cancer Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 936

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

Prakash, R., Zhang, Y., Feng, W., & Jasin, M. (2015) · Cold Spring Harbor Perspectives in Biology

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 869

Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

Xia, B., Sheng, Q., Nakanishi, K., Ohashi, A., Wu, J., Christ, N., Liu, X., Jasin, M., Couch, F. J., & Livingston, D. M. (2006) · Molecular Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 861

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

Liang, F., Han, M., Romanienko, P. J., & Jasin, M. (1998) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCRISPR and Genetic Engineering

Cited by 649

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

Lovejoy, C. A., Li, W., Reisenweber, S., Thongthip, S., Bruno, J., de Lange, T., De, S., Petrini, J. H. J., Sung, P. A., Jasin, M., et al. (2012) · PLoS Genetics

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 629

Frequent chromosomal translocations induced by DNA double-strand breaks

Richardson, C., & Jasin, M. (2000) · Nature

DNA Repair MechanismsGenomic variations and chromosomal abnormalities

Cited by 517

Positional stability of single double-strand breaks in mammalian cells

Soutoglou, E., Dorn, J. F., Sengupta, K., Jasin, M., Nussenzweig, A., Ried, T., Danuser, G., & Misteli, T. (2007) · Nature Cell Biology

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 509

Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences

Stark, J. M., Pierce, A. J., Oh, J., Pastink, A., & Jasin, M. (2004) · Molecular and Cellular Biology

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 501

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

Nakanishi, K., Yang, Y.-G., Pierce, A. J., Taniguchi, T., Digweed, M., D'Andrea, A. D., Wang, Z.-Q., & Jasin, M. (2005) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsBlood disorders and treatments

Cited by 384

Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining

Ghezraoui, H., Piganeau, M., Renouf, B., Renaud, J.-B., Sallmyr, A., Ruis, B., Oh, S., Tomkinson, A. E., Hendrickson, E. A., Giovannangeli, C., et al. (2014) · Molecular Cell

DNA Repair MechanismsCRISPR and Genetic Engineering

Cited by 351

Collaboration and competition between DNA double‐strand break repair pathways

Kass, E. M., & Jasin, M. (2010) · FEBS Letters

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 326

Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Zuccaro, M. V., Xu, J., Mitchell, C., Marin, D., Zimmerman, R., Rana, B., Weinstein, E., King, R. T., Palmerola, K. L., Smith, M. E., et al. (2020) · Cell

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 303

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity

Shakya, R., Reid, L. J., Reczek, C. R., Cole, F., Egli, D., Lin, C.-S., deRooij, D. G., Hirsch, S., Ravi, K., Hicks, J. B., et al. (2011) · Science

BRCA gene mutations in cancerCancer-related Molecular Pathways

Cited by 244

Inter-homologue repair in fertilized human eggs?

Egli, D., Zuccaro, M. V., Kosicki, M., Church, G. M., Bradley, A., & Jasin, M. (2018) · Nature

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 111

p21 promotes error-free replication-coupled DNA double-strand break repair

Mauro, M., Rego, M. A., Boisvert, R. A., Esashi, F., Cavallo, F., Jasin, M., & Howlett, N. G. (2012) · Nucleic Acids Research

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 56

High-resolution functional mapping of RAD51C by saturation genome editing

Olvera-León, R., Zhang, F., Offord, V., Zhao, Y., Tan, H. K., Gupta, P., Pal, T., Robles-Espinoza, C. D., Arriaga-González, F. G., Matsuyama, L. S. A. S., et al. (2024) · Cell

BRCA gene mutations in cancerGenomics and Rare Diseases

Cited by 44

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin

Carver, A., Yu, T.-Y., Yates, L. A., White, T., Wang, R., Lister, K., Jasin, M., & Zhang, X. (2024) · Science

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 25

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin

Carver, A., Yu, T.-Y., Yates, L. A., White, T., Wang, R., Lister, K., Jasin, M., & Zhang, X. (2025) · Science

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 25

Rapid interrogation of cancer cell of origin through CRISPR editing

Feng, W., Cao, Z., Lim, P. X., Zhao, H., Luo, H., Mao, N., Lee, Y. S., Rivera, A. A., Choi, D., Wu, C., et al. (2021) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 25