A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

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Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

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Nucleotide deficiency promotes genomic instability in early stages of cancer development

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Advanced pancreatic carcinoma: current treatment and future challenges

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Stable Interaction between the Products of the BRCA1 and BRCA2 Tumor Suppressor Genes in Mitotic and Meiotic Cells

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How the Fanconi Anemia Pathway Guards the Genome

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Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

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The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

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Ovarian Cancer: In Search of Better Marker Systems Based on DNA Repair Defects

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The Interferon Consensus Sequence Binding Protein (Icsbp/Irf8) Is Required for Termination of Emergency Granulopoiesis

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A mechanism for 1,4-Benzoquinone-induced genotoxicity

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PARPi focus the spotlight on replication fork protection in cancer

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Circulating Tumor Cells in Breast Cancer Patients: A Balancing Act between Stemness, EMT Features and DNA Damage Responses

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FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells

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FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability

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SNM1B/Apollo in the DNA damage response and telomere maintenance

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E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells

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Genome-wide CRISPR screens reveal cyclin C as synthetic survival target of BRCA2

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Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

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Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cyclePreprint

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FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation

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Non-Recombinogenic Functions of Rad51, BRCA2, and Rad52 in DNA Damage Tolerance

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Efficient DNA Repair Mitigates Replication Stress Resulting in Less Immunogenic Cytosolic DNA in Radioresistant Breast Cancer Stem Cells

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FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination

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Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair

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Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors

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Advances in structural studies of recombination mediator proteins

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A Novel Cell-Penetrating Antibody Fragment Inhibits the DNA Repair Protein RAD51

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Structural insight into FANCI–FANCD2 monoubiquitination

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TIPIN depletion leads to apoptosis in breast cancer cells

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Disparate requirements for RAD54L in replication fork reversal

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Comprehensive whole-genome sequencing reveals origins of mutational signatures associated with aging, mismatch repair deficiency and temozolomide chemotherapy

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Risk of Human Papillomavirus Infection in Cancer-Prone Individuals: What We Know

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Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

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A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

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GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells

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Insights into the Possible Molecular Mechanisms of Resistance to PARP Inhibitors

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BRCA1/2 Haploinsufficiency: Exploring the Impact of Losing one Allele

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FANCM branchpoint translocase: Master of traverse, reverse and adverse DNA repair

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To the Rescue: The Fanconi Anemia Genome Stability Pathway Salvages Replication Forks

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Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation

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Activation of the FA pathway mediated by phosphorylation and ubiquitination

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PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice

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Observation and Analysis of RAD51 Nucleation Dynamics at Single-Monomer Resolution

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Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia

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BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1–MCM2 signaling during pregnancy

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Targeting DNA Double-Strand Break (DSB) Repair to Counteract Tumor Radio-resistance

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Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

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The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells

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Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer

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What are the DNA lesions underlying formaldehyde toxicity?

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BRCA2 minor transcript lacking exons 4–7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation

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Synthetic lethality: the road to novel therapies for breast cancer

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DNA polymerase ι compensates for Fanconi anemia pathway deficiency by countering DNA replication stress

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The Fanconi anemia ubiquitin E3 ligase complex as an anti-cancer target

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Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance

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Beyond interstrand crosslinks repair: contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA

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Fork Protection and Therapy Resistance in Hereditary Breast CancerPreprint

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NF-κB at the Crossroads of Normal Mammary Gland Biology and the Pathogenesis and Prevention of BRCA1-Mutated Breast Cancer

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Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 Are Required for Maintaining Histone Methylation Levels and Interact with the Histone Demethylase LSD1/SPR-5 in Caenorhabditis elegans

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Tissue-Specific Carcinogens as Soil to Seed BRCA1/2-Mutant Hereditary Cancers

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Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”

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The Fanconi anemia pathway and Breast Cancer: A comprehensive review of clinical data

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Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region

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p53-dependent crosstalk between DNA replication integrity and redox metabolism mediated through a NRF2-PARP1 axis

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The DNA resection protein CtIP promotes mammary tumorigenesis

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Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L

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FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress

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TCAF1 promotes TRPV2-mediated Ca2+ release in response to cytosolic DNA to protect stressed replication forks

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"Bridging the DNA divide": Understanding the interplay between replication- gaps and homologous recombination proteins RAD51 and BRCA1/2

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The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

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New Era of Mapping and Understanding Common Fragile Sites: An Updated Review on Origin of Chromosome Fragility

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What is wrong with Fanconi anemia cells?

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New origin firing is inhibited by APC/CCdh1activation in S-phase after severe replication stress

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Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas

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Endoscopic findings and esophageal cancer incidence among Fanconi Anemia patients participating in an endoscopic surveillance program

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Women’s cancers: how the discovery of BRCA genes is driving current concepts of cancer biology and therapeutics

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Functional Characterization of PALB2 Variants of Uncertain Significance: Toward Cancer Risk and Therapy Response Prediction

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A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells

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Mechanism of immune activation mediated by genomic instability and its implication in radiotherapy combined with immune checkpoint inhibitors

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Strategies for the prevention or reversal of PARP inhibitor resistance

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Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells

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