SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

Cited by (446)

Items 401–446 of 446

  1. NAD + -Dependent Deacetylases and Medical Therapy
    Ashok Kumar, Louisa Ben-Aderet, Jinan Elayyan, Mona Dvir‐Ginzberg · 2016 · Elsevier eBooks
  2. Ligand Binding and Catalysis in Selected Sirtuin Isozymes
    Junru Yu · 2016 · NDSU Repository (North Dakota State University)
  3. Sirtuins in Cancer – Emerging Role as Modulators of Metabolic Reprogramming
    Jaewon James Lee, Karina N. Gonzalez Herrera, Marcia C. Haigis · 2016 · Springer eBooks
  4. Spatio-Temporal Control of Cellular and Organismal Physiology by Sirtuins
    Shaunak Deota, Namrata Shukla, Ullas Kolthur‐Seetharam · 2017 · Journal of the Indian Institute of Science
  5. A Role for Sirtuins in Maintaining Mammalian Lifespan and Healthspan
    William Giblin · 2017 · Deep Blue (University of Michigan)
  6. Energy Metabolism and Epigenetics
    Scott J. Bultman · 2017 · Springer eBooks
  7. Reactive Acyl-CoA Species and Deacylation by the Mitochondrial Sirtuins
    Kathleen A. Hershberger, Matthew D. Hirschey · 2018 · Elsevier eBooks
  8. Análise da expressão gênica das sirtuínas nos somatotropinomas e adenomas hipofisários clinicamente não funcionantes e sua relação com a invasividade tumoral
    Isabella Pacetti Pajaro Grande · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  9. Insights into Cellular Stress Revealed by SIRT7
    Yufei Liu · 2014 · eScholarship (California Digital Library)
  10. The antiviral mechanism and viral antagonism of host histone deacetylase 4 in influenza A virus infection
    Henry D. Galvin · 2020 · Otago University Research Archive (University of Otago)
  11. Molecular Mechanisms Underlying the Role of Mitophagy in Neurodegeneration
    Abhilasha Ahlawat, Meenakshi Kaira, Vaibhav Walia, Munish Garg · 2020 · Advances in medical diagnosis, treatment, and care (AMDTC) book series
  12. SIRT4 Overexpression Promotes the Inhibition of Cell Proliferation and Invasion in Prostate Cancer
    Abdul-Nazif Mahmud, Feilun Cui, Xue Bo, Jianpeng Hu, Tingjun Liu, Muslimat Kehinde Adebis, Said Abdulrahman Salim Mzee, Aaron Gia Kanton · 2020 · International Journal of Scientific Research in Science and Technology
  13. Sirtuins and the hallmarks of cancer
    Talita Helen Bombardelli Gomig, Tayana Schultz Jucoski, Érika Pereira Zambalde, Alexandre Luiz Korte de Azevedo, Daniela Fiori Gradia, Enilze M.S.F. Ribeiro · 2021 · Elsevier eBooks
  14. Sirtuins in mechanistic target of rapamycin complex 1 signaling
    Jesús Burillo, Patricia Marqués, Beatriz Jiménez, Carlos González-Blanco, Manuel Benito, Carlos Guillén · 2021 · Elsevier eBooks
  15. Sirtuin signaling in hematologic malignancies
    Ryan Austin Denu · 2021 · Elsevier eBooks
  16. Sirtuins as key players in aging and kidney dysfunction
    Luca Perico, Ariela Benigni · 2021 · Elsevier eBooks
  17. Uma visão estrutural sobre componentes do processo de adaptação metabólica de tumores
    A.L.B. Ambrosio · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  18. Advancing knowledge about the health issues of Australia's defence personnel and veterans
    Susan A. Treloar, Katherine M. Kirk, ALEXANDER COWELL McFARLANE, Peter Nasveld, Brad McCall · 2010
  19. Energy Metabolism and Epigenetics
    Scott J. Bultman · 2019 · Springer eBooks
  20. SIRT4 functions as a tumor suppressor in prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
    Liangliang Cai, Zhuhui Ge, Yunqiu Xu, Pingliang Sun, Guoyu Huang · 2022 · Research Square
  21. Sirtuins
    Frank K. Huynh, Eoin McDonnell, Kristin A. Anderson, Matthew D. Hirschey · 2015 · Wiley eBooks
  22. SIRT4 functions as a tumor suppressor in prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
    Liangliang Cai, Zhuhui Ge, Yunqiu Xu, Pingliang Sun, Guoyu Huang · 2022 · Research Square
  23. Application of nuclear magnetic resonance spectroscopy for the detection of metabolic changes in blood cells with defective DNA repair
    Gaelle Vanderstichelen · 2022 · Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt)
  24. SIRT4 Loss Reprograms Intestinal Nucleotide Metabolism to Support Proliferation and Survival Following Perturbation of Homeostasis
    Sarah A. Tucker, Sejal Vyas, Albert Park, Shakchhi Joshi, Aslihan Inal, Tiffany Lam, Emily Tan, Kevin M. Haigis, Marcia C. Haigis · 2022 · SSRN Electronic Journal
  25. SIRT4 enhances the sensitivity of colorectal cancer cells to 5-FU by inhibiting ammonia-mediated autophagy
    Bo Xu, Liangliang Cai, Hua Xiao, Guohao Cai, Pingliang Sun, Guoyu Huang · 2023 · Research Square
  26. SIRT4 Overcomes 5-Fluorouracil Associated Chemoresistance by Inhibiting Autophagy through Inhibition of ammonia production
    Bo Xu, Xiaojing Cai, Hua Xiao, Guoyu Huang · 2023 · Research Square
  27. Osteoclast-Cancer Cell Metabolic Symbiosis Renders PARP Inhibitor Therapy Resistance in Bone Metastasis
    Huijuan Fan, Zhanao Xu, Ke Yao, Bingxin Zheng, Yuan Zhang, Xuxiang Wang, Tengjiang Zhang, Xuan Li, Haitian Hu, Bin Yue et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling
    Mehrnaz Mehrabipour, Radovan Dvorský, Saeideh Nakhaei‐Rad, Alexander Lang, Patrick Verhülsdonk, Mohammad Reza Ahmadian, Roland P. Piekorz · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  29. In silico analysis of sirtuin-type histone deacetylase genes in sugar beet (Beta vulgaris L.)
    Seher Yolcu · 2024 · Frontiers in Life Sciences and Related Technologies
  30. SIRTifying intestinal nucleotide metabolism
    Shweta Tiwary, Cristina D. Guerena, Jenna L. Jewell · 2024 · Trends in Endocrinology and Metabolism
  31. The Role of NAD+-Dependent Signal Mechanisms in Cancer Development and Treatment
    Ting Lu, Zheng‐Hong Qin, Junchao Wu · 2025 · Springer eBooks
  32. Associations of Midlife Leukocyte Telomere Length With Measures of Left Atrial Function in Community‐Dwelling Older Adults: The ARIC Study
    Romil R Parikh, Nathan Pankratz, John Lane, Dan E. Arking, Anne A. Eaton, Lin Y. Chen, Pamela L. Lutsey, Weihong Tang · 2025 · Journal of the American Heart Association
  33. CREB3L4 upregulates SIRT4 expression to increase GABA/glutamate ratio and mitochondrial homeostasis for epilepsy suppression
    Haoyu Liu, Qiannan Song, Jiayi Jin, Hong Chen · 2025 · Epilepsy Research
  34. Sirtuins as a Double-Edged Sword in Cancer: From Molecular Mechanisms to Therapeutic Opportunities
    Núria Sima, Laia Bosch‐Presegué, Alejandro Vaquero · 2014 · Springer eBooks
  35. Additional file 1 of HIF-1α-dependent miR-424 induction confers cisplatin resistance on bladder cancer cells through down-regulation of pro-apoptotic UNC5B and SIRT4
    Yu Meng, Toshinori Ozaki, Sun, Dan, Haotian Xing, Wei, Baojun, Jun An, Yang, Jieping, Gao, Ying, Liu, Shuangjie, Kong, Chuize et al. · 2020 · Figshare
  36. An integrated bioinformatics and multi-omics investigation of the sirtuin family to identify their prognostic importance in human cancers
    Md. Shahedur Rahman, Rizone Al Hasib, Md Rezanur Rahman, Polash Kumar Biswas, Abu Reza, Munzura Khatun, Mohammad Abu Hena Mostofa Jamal · 2025 · Tumor Biology
  37. Etude des modifications épigénétiques en fonction de l'agressivité du cancer sporadique du sein : l'implication de l'histone désacétylase SIRT1 dans la progression tumorale
    Khaldoun T Rifai · 2018 · theses.fr (ABES)
  38. ATGL-catalyzed lipid catabolism promotes DNA double-strand break repair
    Mahima Devarajan, Rachel K. Meyer, Gavin Fredrickson, William A. Hofstadter, Mara T. Mashek, Mari V. Reid, Evan W. Kerr, Anna Bartelt, Peter Gutenberger, Simone Intriago et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Carvacrol-Based Formulations Modulate Sirtuins and Exert Cytotoxic and Antimicrobial Effects in Lung Cancer Models
    Selin Aktar Kiremitci, Ayşe Simay Metin, İmren Hasoğlu, Mert Gecim, Didem Demir, Hande Karagedik, Pınar Yurdakul, Öykü Gönül Geyik · 2026 · Antioxidants
  40. Sirtuin proteins: structure, functions, and evolutionary insights
    Neetu Sachan, P. K. Varshney, Phool Chandra, Pradeep Singh · 2026 · Elsevier eBooks
  41. Bone marrow mesenchymal stem cell-derived CHI3L1 protected against Helicobacter pylori-induced gastric mucosal damage by promoting DNA damage repair via regulating CTCF/CPT1A
    Wang Qianqian, Xiaoxiao Wang, Yongbin Wang, Chen Jing, Hu Zhang · 2026 · Journal of Biological Chemistry
  42. Sirtuin 4 is downregulated in oral carcinogenesis
    Tanatat Apiwessa, Paranin Chaicharncheep, Somchai Yodsanga, Theerapat Chanamuangkon, Ekarat Phattarataratip · 2026 · Odontology
  43. The sirtuin family: from mechanisms to therapy
    Jiaying Xiao, Yiling Li, Yuyao Xie, Yuan Chen, Qihan Liu, Hao Li, Rui Sun · 2026 · Molecular Biomedicine
  44. BindingDB Entry 50021643: Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity.
    BindingDB · 2025 · UC San Diego
  45. BindingDB Entry 50010551: An overview of Sirtuins as potential therapeutic target: Structure, function and modulators.
    BindingDB · 2021 · UC San Diego
  46. BindingDB Entry 50020903: Ligand-based design and synthesis of new trityl histamine and trityl cysteamine derivatives as SIRT2 inhibitors for cancer therapy.
    BindingDB · 2025 · UC San Diego