Finley, Lydia W. S.

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

Carey, B. W., Finley, L. W. S., Cross, J. R., Allis, C. D., & Thompson, C. B. (2015) · Nature

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 1,007

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

Finley, L. W. S., Carracedo, A., Lee, J., Souza, A., Egia, A., Zhang, J., Teruya-Feldstein, J., Moreira, P. I., Cardoso, S. M., Clish, C. B., et al. (2011) · Cancer Cell

Cancer, Hypoxia, and MetabolismSirtuins and Resveratrol in Medicine

Cited by 782

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

Verdin, E., Hirschey, M. D., Finley, L. W. S., & Haigis, M. C. (2010) · Trends in Biochemical Sciences

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 661

Adrenergic nerves activate an angio-metabolic switch in prostate cancer

Zahalka, A. H., Arnal-Estapé, A., Maryanovich, M., Nakahara, F., Cruz, C. D., Finley, L. W. S., & Frenette, P. S. (2017) · Science

Cancer, Stress, Anesthesia, and Immune ResponseAngiogenesis and VEGF in Cancer

Cited by 548

Regulation and function of the mammalian tricarboxylic acid cycle

Arnold, P. K., & Finley, L. W. S. (2023) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 535

Hypoxia Induces Production of L-2-Hydroxyglutarate

Intlekofer, A. M., Dematteo, R. G., Venneti, S., Finley, L. W. S., Lu, C., Judkins, A. R., Rustenburg, A. S., Grinaway, P. B., Chodera, J. D., Cross, J. R., et al. (2015) · Cell Metabolism

Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation

Cited by 513

Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia

Ye, J., Fan, J., Venneti, S., Wan, Y.-W., Pawel, B. R., Zhang, J., Finley, L. W. S., Lu, C., Lindsten, T., Cross, J. R., et al. (2014) · Cancer Discovery

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 452

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

Jeong, S. M., Xiao, C., Finley, L. W. S., Lahusen, T., Souza, A. L., Pierce, K., Li, Y.-H., Wang, X., Laurent, G., German, N. J., et al. (2013) · Cancer Cell

Sirtuins and Resveratrol in MedicineCancer, Hypoxia, and Metabolism

Cited by 445

Metabolic signatures of cancer cells and stem cells

Intlekofer, A. M., & Finley, L. W. S. (2019) · Nature Metabolism

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 322

A non-canonical tricarboxylic acid cycle underlies cellular identity

Arnold, P. K., Jackson, B. T., Paras, K. I., Brunner, J. S., Hart, M. L., Newsom, O. J., Alibeckoff, S. P., Endress, J., Drill, E., Sullivan, L. B., et al. (2022) · Nature

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 304

α-Ketoglutarate links p53 to cell fate during tumour suppression

Morris, J. P., Yashinskie, J. J., Koche, R., Chandwani, R., Tian, S., Chen, C.-C., Baslan, T., Marinkovic, Z. S., Sánchez-Rivera, F. J., Leach, S. D., et al. (2019) · Nature

Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism

Cited by 296

Metabolic regulation of chromatin modifications and gene expression

Schvartzman, J. M., Thompson, C. B., & Finley, L. W. S. (2018) · Journal of Cell Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 233

The coordination of nuclear and mitochondrial communication during aging and calorie restriction

Finley, L. W. S., & Haigis, M. C. (2009) · Ageing Research Reviews

Mitochondrial Function and PathologySirtuins and Resveratrol in Medicine

Cited by 207

Metabolic coordination of cell fate by α-ketoglutarate-dependent dioxygenases

Baksh, S. C., & Finley, L. W. S. (2021) · Trends in Cell Biology

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

Cited by 165

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

German, N. J., Yoon, H., Yusuf, R. Z., Murphy, J. P., Finley, L. W. S., Laurent, G., Haas, W., Satterstrom, F. K., Guarnerio, J., Zaganjor, E., et al. (2016) · Molecular Cell

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 156

Extracellular serine controls epidermal stem cell fate and tumour initiation

Baksh, S. C., Todorova, P. K., Gur-Cohen, S., Hurwitz, B., Ge, Y., Novak, J. S. S., Tierney, M. T., dela Cruz-Racelis, J., Fuchs, E., & Finley, L. W. S. (2020) · Nature Cell Biology

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

Cited by 128

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Finley, L. W. S., Lee, J., Souza, A., Desquiret-Dumas, V., Bullock, K., Rowe, G. C., Procaccio, V., Clish, C. B., Arany, Z., & Haigis, M. C. (2012) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 102