mTOR Signaling in Disease

Dazert, Eva, Hall, Michael N·2011·Current Opinion in Cell Biology

Cited by (461)

Items 401–461 of 461

  1. Metformin augments major cytoplasmic organization except for spindle organization in oocytes cultured under hyperglycemic and hyperlipidemic conditions: An in vitro study
    Amrutha Nedumbrakkad Kunnath, Shravani Kanakadas Parker, Daphne Norma Crasta, Jyolsna Ponnaratta Kunhiraman, Vanishree Vasave Madhvacharya, Sandhya Kumari, Guruprasad Nayak, Vani Lakshmi R, Prashant Kumar Modi, Thottethodi Subrahmanya Keshava Prasad et al. · 2024 · Toxicology and Applied Pharmacology
  2. Bioinformatics Approach to mTOR Signaling Pathway-Associated Genes and Cancer Etiopathogenesis
    Kürşat Özdilli, Gözde Öztan, Demet Kıvanç, Süleyman Rüştü Oğuz, Fatma Savran Oğuz, Hayriye Şentürk Çiftçi · 2025 · Genes
  3. Adaptive crosstalk between polyamine metabolism, translation, and autophagy sustains energy homeostasis in mammals during starvation: a scoping review
    Kayhan Karimi, Sigrid C. Roberts, Nicola S. Carter, Sebastian J. Hofer, Reza Karimi · 2026 · Amino Acids
  4. Organelle Stress and mTOR in Aging-Associated Inflammation
    Giovambattista Pani · 2013 · Elsevier eBooks
  5. Pancreatic tumors: an overview
    Carlos A Tirado, David Shabsovich, J Ji, David W. Dawson · 2014 · Atlas of Genetics and Cytogenetics in Oncology and Haematology
  6. Effects of rapamycin on granulation formation in response to centrally doubled coiled stents as a tracheal substitute
    Masayuki Kubota, Yasunobu Matsuda, Shun Fujimaki, Mami Osawa, Toshifumi Wakai, Kengo Nakaya · 2013 · Journal of Pediatric Surgery
  7. Molecular Characterization of Primary Human Astrocytes Using Digital Gene Expression Analysis
    Jin Wook Kim, Ju Ho Jeong · 2019 · Korean Journal of Neurotrauma
  8. 3, 3′- (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFRY1086 Phosphorylation
    Qurat Ul Ain, Abhijit Basu, Muhammad Iqbal Choudhary, Karin Scharffetter‐­Kochanek · 2022 · Molecules
  9. MicroRNA Regulation of mTOR Function
    Marina E. Zambrotta, John D. Houlé · 2015 · Elsevier eBooks
  10. Novel non‐invasive molecular signatures for oral cavity cancer, by whole transcriptome and small non‐coding RNA sequencing analyses: Predicted association with PI3K / AKT / mTOR pathway
    Dimitra P. Vageli, Panagiotis G. Doukas, Jeffrey P. Townsend, Curtis R. Pickering, Benjamin L. Judson · 2024 · Cancer Medicine
  11. Neuronal Cilia and Obesity
    Nicolas F. Berbari, Raymond C. Pasek, Bradley K. Yoder · 2012 · Springer eBooks
  12. Review on the molecular signaling pathways involved in controlling cancer stem cells and treatment
    Flora Forouzesh, Niloofar Agharezaee · 2018 · The Journal of Qazvin University of Medical Sciences
  13. Effect of caloric restriction on aging and neurodegenerative diseases
    Фефелова Юлия Анатольевна, Б.Ю. Мурашев · 2022 · Zhurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia»
  14. Clinical and genetic analysis of patients with segmental overgrowth features and somatic mammalian target of rapamycin (mTOR) pathway disruption: Possible novel clinical issues
    Ferruccio Romano, Francesca Madia, Patrizia De Marco, Marzia Ognibene, Sara Guerrisi, Marcello Scala, Michele Iacomino, Sımona Baldassari, Nadia Vercellino, Francesca Manunza et al. · 2022 · Birth Defects Research
  15. Ribosome-Associated GTPase Drg1 Links Cytosolic Translation to Mitochondrial Homeostasis
    Sounak Saha, Aryaman Bhattacharya, Hong Jin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Targeting the mTOR signalling pathway for prevention and therapy of tuberous sclerosis in mouse models
    Maria Kalogerou · 2013 · ORCA Online Research @Cardiff (Cardiff University)
  17. The Potential Molecular Therapeutic Approach in Targeting Ovarian Clear Cell Carcinoma
    David W Chan Hextan YS Ngan · 2012 · Gynecology & Obstetrics
  18. Targeting endoplasmic reticulum stress and autophagy in cancer
    C. E. Johnson · 2015 · ORCA Online Research @Cardiff (Cardiff University)
  19. mTOR pathway dysregulation and the role of rapamycin and its derivatives in management of neurological disorders
    Agnieszka Elwira Dębkowska, Sergiusz Jóźwiak · 2015 · Child Neurology
  20. MicroRNA Regulation of mTOR Function
    Marina E. Zambrotta, John D. Houlé · 2014 · Elsevier eBooks
  21. Role of Autophagy in Cellular Defense Against Inflammation
    Eun‐Kyeong Jo, Dong–Min Shin, Jae–Min Yuk · 2013 · Elsevier eBooks
  22. Expressão dos genes da via mTORC1 e seu envolvimento nas Neoplasias Mieloproliferativas
    Natália de Souza Nunes · 2016
  23. The Role of Integrins in Support of Pancreatic Function, Survival and Maturation
    Matthew Riopel · 2014 · Scholarship@Western (Western University)
  24. Environmental Signaling through the Target of Rapamycin Complex 1 (TORC1) and the Regulation of Epigenetic Mechanisms
    Jason J. Workman · 2016
  25. Sum Up and Future Research
    Dominique Meynial‐Denis · 2019 · CRC Press eBooks
  26. Identification of interacting partners of mammalian target of rapamycin complex 1 (mTORC1) assembly in human lymphocytes
    Hazır Rahman · 2012
  27. Plasticity of Mesenchymal Stem Cells based on Immune Regulation Network
    Tingting Ren · 2019 · International Journal of Sciences
  28. Pathological circadian rhythm states driven by CK2 and noise
    Z. Malik, Y. Fatima, Md. Jahoor Alam, R. K. Brojen Singh · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  29. DTA expression in mTas1r3+ cells lead to male infertility
    Feng Li, Bowen Niu, Lingling Liu · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Hydrogen Sulfide Ameliorates High Glucose-induced Inflammation Through SIRT1-mTOR/NF-κB Signaling Pathway in HT-22 cells
    Xinrui Li, Yinghua Yu, Peiquan Yu, Ting Xu, Jiao Liu, Yuan Guo Cheng, Xia Yang, Xiaoying Cui, Yin Cui, Yi Liu · 2020 · Research Square
  31. A Sphingolipid-mTORC1 Nutrient-Sensing Machinery Enables Animal Development by Suppression of the Intestinal Peroxisome Relocation, Hormone Secretion and the Gut-Brain Crosstalk
    Na Li, Beilei Hua, Qing Chen, Meiyu Ruan, Fukang Teng, Mengnan Zhu, Li Zhang, Shen Huali, Huanhu Zhu · 2021 · SSRN Electronic Journal
  32. mTOR controls lysosome function by modulating the Rab7 GTPase
    Zechariah Martin · 2021
  33. The Role of Insulin Signaling in Mammalian Peripheral Taste Tissue: From Taste Modulation to Maintenance of Taste Bud Homeostasis
    Shingo Takai, Noriatsu Shigemura · 2021 · KAGAKU TO SEIBUTSU
  34. Effects of Bpaf on Apoptosis and Autophagy of Mice Heart Tissue
    Lihui Xu, Huan Zhang, Jin-sa Zhou, Jiaxin Shi, Jiajie Jiang, Wenxiu Hu, Feifei Guo, Xuehui Liu, Suju Sun · 2022 · SSRN Electronic Journal
  35. Environmental Signaling through the Target of Rapamycin Complex 1 (TORC1) and the Regulation of Epigenetic Mechanisms
    Jason Workman · 2016
  36. Análisis molecular del tipo de muerte celular inducido por la terapia coadyudante: metformina y el oxamato de sodio como inhibidores de la vía mTOR y la glucólisis en un modelo celular triple negativo de cáncer de mama
    Verónica García-Castillo · 2018
  37. Sum Up and Future Research
    Dominique Meynial‐Denis · 2017 · CRC Press eBooks
  38. In Silico Study of ULK1 Gene as a Susceptible Biomarker for Neurodegeneration
    Prekshi Garg, Neha Srivastava, Prahlad Kishore Seth, Prachi Srivastava · 2022 · Proceedings of the National Academy of Sciences India Section B Biological Sciences
  39. Circ-MEG3 inhibits the malignant proliferation of human cervical cancer cells
    Tong Pan, Shuang Liang, Yanna Li · 2024 · Research Square
  40. Investigating the Mechanistic Target of Rapamycin and Analogous Pathways in Cardiovascular Diseases to Augment Cardiac Functionality
    Cheryl Rhea Lewis · 2025 · Jordan Journal of Pharmaceutical Sciences
  41. AcetyLeish: acetylation-driven control of stage differentiation and virulence in Leishmania mexicana
    Nilmar Silvio Moretti, Suellen Rodrigues Maran, Anelise Gonçalves Marino, Ariely Barbosa Leite, Bruno Souza Bonifácio, Miguel Nascimento Garcia, Maria de La Salette da Costa, Ana Caroline de Castro Nascimento Sousa, Paulo Otávio Lourenço Moreira, Alessandra Mara de Sousa et al. · 2025 · Research Square
  42. Chromatin stability safeguards mitochondrial homeostasis and prevents mTORC1 hyperactivation
    Vinoth Sigamani, Mohd Yousuf, Daniel L. Johnson, Brian D. Strahl, R. Nicholas Laribee · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Additional file 1 of Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress
    Liu, Chen-Yue, JianBei Chen, YueYun Liu, Zhou, Xue-Ming, Zhang, Man, Jiang, You-Ming, Ma, Qing-Yu, Zhe Xue, Zhao, Zong-Yao, Li, Xiao-Juan et al. · 2022 · Figshare
  44. Additional file 4 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  45. Additional file 6 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  46. Additional file 5 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  47. Additional file 3 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  48. Additional file 2 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  49. Additional file 1 of Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
    Shon, Woo-Jeong, Jae Won Song, Seung Hoon Oh, Lee, Keon-Hee, Hobin Seong, Hyun Ju You, Seong, Je Kyung, Shin, Dong-Mi · 2023 · Figshare
  50. The mTOR Inhibitor Rapamycin Attenuates Ozone-Induced Airway Inflammation and Emphysema In Mice
    Xue Tian, Lei Han, Yuning George Huang, Yan Zhou, Xue Zhang, Min Zhang · 2026 · Journal of Inflammation Research
  51. miRNA675-5p inhibitor’s dual role as novel therapeutic alternative or sensitizing treatment in resistant glioma models
    Cristina Martelli, Marcella Bonanomi, Chiara Pellizzer, Alessandro Giammona, Sofia Remedia, Martina Nespoli, Daniela Gaglio, Daniele Capitanio, Danilo Porro, Luisa Ottobrini et al. · 2026 · Molecular Therapy — Nucleic Acids
  52. The regulatory role of mTOR core pathways in mitochondrial autophagy
    Zao LUO, Yu-Kai CHENG, Jia-Qi SHEN, Min-Juan WU · 2026 · Shengming kexue
  53. Modulation of the stress-activated protein kinases Hog1/p38 and a TORC1-dependent kinase by curcumin is stress granule-dependent
    Liuyi Zheng, Zenae K. Cherry, Gabriela Soltys, Marisa Penner, Natalie Samuell, Dini Welivita, Brianna Thomas, Jonathan S. Fisher, Yuqi Wang · 2026 · Journal of Biological Chemistry
  54. Impact des immunoglobulines tronquées produites par saut d’exon dans les plasmocytes : vers des approches thérapeutiques utilisant des oligonucléotides antisens
    Jean-Marie Lambert · 2020 · theses.fr (ABES)
  55. Functional characterization of the GATOR1 complex in cisplatin resistance
    Zhenrui Pan · 2024
  56. The role of the GATOR1 complex in mitochondrial function and quality control
    Hanxiao Zhang · 2025 · theses.fr (ABES)
  57. The mTOR-mLST8 binding profile through molecular simulation, free-energy calculation, per-residue decomposition and hydrogen bonds identification
    Júlia Gomes, Roger Kist, Fernando Berton Zanchi, Rafael Andrade Caceres · 2026 · In Silico Research in Biomedicine
  58. Chromatin stability safeguards mitochondrial homeostasis and restrains TORC1 signaling
    Vinoth Sigamani, Mohd Yousuf, Daniel L. Johnson, Brian D. Strahl, R. Nicholas Laribee · 2026 · PLoS Genetics
  59. BindingDB Entry 50001049: Design, synthesis and biological evaluation of novel 3H-imidazole [4,5-b] pyridine derivatives as selective mTOR inhibitors.
    BindingDB · 2020 · UC San Diego
  60. Manipulating the Tumor Microenvironment for Therapeutic Benefit
    Kate M. Bailey · 2014 · Digital Commons - University of South Florida (University of South Florida)
  61. Characterization of the mechanisms underlying alterations in macroautophagy and survival signalling in Huntington’s disease
    Laura Rué Cabré · 2012 · Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)