The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Electroactive anti-oxidant polyurethane elastomers with shape memory property as non-adherent wound dressing to enhance wound healing
Abstract
Abstract Development of wound dressings that not only have multiple advantages including good barrier properties, elasticity and shape memory properties, but also show anti-infection, anti-oxidative and promote cell adhesion, proliferation to enhance wound healing process, remains an ongoing challenge in the skin tissue engineering. Herein, we designed and synthesized a series of electroactive shape memory polyurethane-urea elastomers by combining the mechanical properties of polycaprolactone (PCL) segments, wettability of polyethylene glycol (PEG) segments and electroactivity of aniline trimer (AT) segments, as antibacterial, anti-oxidant and electroactive film dressing for cutaneous wound healing. The films displayed suitable hydrophilicity and swelling ratio, excellent mechanical and shape memory properties, electroactivity, free radical scavenging capacity, non-adherent property and biocompatibility. Excitingly, the electroactive film with an optimal concentration of 12 wt% AT promoted mouse fibroblasts (L929) adhesion and proliferation, and it also significantly accelerated in vivo wound healing process than no-electroactive film and commercial dressing (Tegaderm™ film) through promoting granulation tissue thickness and collagen deposition in a full-thickness skin defect model. Moreover, after loading with vancomycin as antibacterial agents, the rate of wound healing is further enhanced. In summary, the electroactive shape memory polyurethane-urea films significantly promoted in vivo wound healing process attributed to its multifunctional properties indicated that they are excellent candidates as film wound dressing.
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1 retracted
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Self-citationBiomaterials based on chitin and chitosan in wound dressing applications
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Self-citationMultimaterial 4D Printing with Tailorable Shape Memory Polymers
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Natural and synthetic polymers for wounds and burns dressing
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Cited by
Functional Hydrogels as Wound Dressing to Enhance Wound Healing
Liang, Y., He, J., & Guo, B. (2021) · ACS Nano · doi:10.1021/acsnano.1c04206 · Cited by 3,135
Self-citationLiang, Y., Li, Z., Huang, Y., Yu, R., & Guo, B. (2021) · ACS Nano · doi:10.1021/acsnano.1c00204 · Cited by 1,083
Self-citationZhao, X., Liang, Y., Huang, Y., He, J., Han, Y., & Guo, B. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910748 · Cited by 814
Self-citationLu, S., Zhang, X., Tang, Z., Xiao, H., Zhang, M., Liu, K., Chen, L., Huang, L., Ni, Y., & Wu, H. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.129329 · Cited by 266
Recent advances in tissue engineering scaffolds based on polyurethane and modified polyurethane
Naureen, B., Haseeb, A. S. M. A., Basirun, W. J., & Muhamad, F. (2021) · Materials Science and Engineering: C · doi:10.1016/j.msec.2020.111228 · Cited by 200
Metadata
- Authors
- Li, M., Chen, J., Shi, M., Zhang, H., Ma, P. X., & Guo, B.
- Venue
- Chemical Engineering Journal
- Publisher
- Elsevier BV
- Published
- 2019-11
- Volume
- 375
- Pages
- 121999
- ISSN
- 1385-8947 (ISSN-L)
- OpenAlex
- W2951494028
- Cited by
- 322
- References
- 71
- FWCI
- 27.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, M., Chen, J., Shi, M., Zhang, H., Ma, P. X., & Guo, B. (2019). Electroactive anti-oxidant polyurethane elastomers with shape memory property as non-adherent wound dressing to enhance wound healing. Chemical Engineering Journal. https://doi.org/10.1016/j.cej.2019.121999
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