Exosome-coated silk fibroin 3D-scaffold for inducing osteogenic differentiation of bone marrow derived mesenchymal stem cells
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A recent study showed that exosome-coating of biomaterials accelerated hBMSC cell adhesion, proliferation, osteogenic differentiation, and also the transport of numerous pro-angiogenic biomolecules, such as VEGF.
“A recent study showed that exosome-coating of biomaterials accelerated hBMSC cell adhesion, proliferation, osteogenic differentiation [59], and also the transport of numerous pro-angiogenic biomolecules, such as the vascular endothelial growth factor (VEGF) [60,61].”
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- Authors
- Kyung Kim, D., Lee, S., Kim, M., Jeong, Y., & Lee, S.
- Affiliations
- CHA University (KR)
- CHA University Bundang Medical Center (KR)
- Corresponding author
- Lee, Soonchul
- Venue
- Chemical Engineering Journal
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 406
- Pages
- 127080
- ISSN
- 1385-8947 (ISSN-L)
- OpenAlex
- W3088854575
- Cited by
- 57
- References
- 41
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 19 · 2023: 5 · 2022: 6 · 2021: 9
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Update notices
- erratum (2025-10-01)
- Open access
- closed
- Locations
- Chemical Engineering Journal (publishedVersion)
- Funders
- Ministry of Science and ICT, South Korea (2019R1C1C1004017)
- Ministry of Health and Welfare (HI16C1559)
- National Research Foundation of Korea
- Korea Health Industry Development Institute
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Keywords
- exosomes, silk fibroin, 3D scaffolds, osteogenic differentiation, mesenchymal stem cells, bone regeneration, calvarial defect, adipose-derived stem cells, bone marrow-derived mesenchymal stem cells
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