Cryptic Pol II Transcripts Are Degraded by a Nuclear Quality Control Pathway Involving a New Poly(A) Polymerase

Global analysis of protein localization in budding yeast

Huh, W.-K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., & O'Shea, E. K. (2003) · Nature · doi:10.1038/nature02026 · Cited by 4,248

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

De Santa, F., Barozzi, I., Mietton, F., Ghisletti, S., Polletti, S., Tusi, B. K., Muller, H., Ragoussis, J., Wei, C.-L., & Natoli, G. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000384 · Cited by 934

Non-coding RNAs as regulators of gene expression and epigenetics

Kaikkonen, M. U., Lam, M. T. Y., & Glass, C. K. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr097 · Cited by 764

RNA Quality Control in Eukaryotes

Doma, M. K., & Parker, R. (2007) · Cell · doi:10.1016/j.cell.2007.10.041 · Cited by 345

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway

Chang, H.-M., Triboulet, R., Thornton, J. E., & Gregory, R. I. (2013) · Nature · doi:10.1038/nature12119 · Cited by 341

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts

Meola, N., Domanski, M., Karadoulama, E., Chen, Y., Gentil, C., Pultz, D., Vitting-Seerup, K., Lykke-Andersen, S., Andersen, J. S., Sandelin, A., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.09.025 · Cited by 290

Extensive Degradation of RNA Precursors by the Exosome in Wild-Type Cells

Gudipati, R. K., Xu, Z., Lebreton, A., Séraphin, B., Steinmetz, L. M., Jacquier, A., & Libri, D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.08.018 · Cited by 236

The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex

Halbach, F., Reichelt, P., Rode, M., & Conti, E. (2013) · Cell · doi:10.1016/j.cell.2013.07.017 · Cited by 210

Transcriptome-wide Analysis of Exosome Targets

Schneider, C., Kudla, G., Wlotzka, W., Tuck, A., & Tollervey, D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.08.013 · Cited by 195

Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex

Weick, E.-M., Puno, M. R., Januszyk, K., Zinder, J. C., DiMattia, M. A., & Lima, C. D. (2018) · Cell · doi:10.1016/j.cell.2018.05.041 · Cited by 153

A tale of non-canonical tails: gene regulation by post-transcriptional RNA tailing

Yu, S., & Kim, V. N. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0246-8 · Cited by 142

Quality control of transcription start site selection by nonsense-mediated-mRNA decay

Malabat, C., Feuerbach, F., Ma, L., Saveanu, C., & Jacquier, A. (2015) · eLife · doi:10.7554/elife.06722 · Cited by 134

C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing

Schilders, G., van Dijk, E., & Pruijn, G. J. M. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm082 · Cited by 132

The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs

Lemay, J.-F., D'Amours, A., Lemieux, C., Lackner, D. H., St-Sauveur, V. G., Bähler, J., & Bachand, F. (2010) · Molecular Cell · doi:10.1016/j.molcel.2009.12.019 · Cited by 112

Exo- and Endoribonucleolytic Activities of Yeast Cytoplasmic and Nuclear RNA Exosomes Are Dependent on the Noncatalytic Core and Central Channel

Wasmuth, E. V., & Lima, C. D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.07.012 · Cited by 114

Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy

Burns, D. T., Donkervoort, S., Müller, J. S., Knierim, E., Bharucha-Goebel, D., Faqeih, E. A., Bell, S. K., AlFaifi, A. Y., Monies, D., Millan, F., et al. (2018) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2018.03.011 · Cited by 88

The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

Fox, M. J., Gao, H., Smith-Kinnaman, W. R., Liu, Y., & Mosley, A. L. (2015) · PLOS Genetics · doi:10.1371/journal.pgen.1004999 · Cited by 61

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

Lingaraju, M., Johnsen, D., Schlundt, A., Langer, L. M., Basquin, J., Sattler, M., Heick Jensen, T., Falk, S., & Conti, E. (2019) · Nature Communications · doi:10.1038/s41467-019-11339-x · Cited by 55

Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome

Gerlach, P., Garland, W., Lingaraju, M., Salerno-Kochan, A., Bonneau, F., Basquin, J., Jensen, T. H., & Conti, E. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.04.011 · Cited by 55

Regulation of anti-sense transcription by Mot1p and NC2 via removal of TATA-binding protein (TBP) from the 3′-end of genes

Koster, M. J. E., & Timmers, H. T. M. (2015) · Nucleic Acids Research · doi:10.1093/nar/gku1263 · Cited by 55

The splicing factor SRSF3 is functionally connected to the nuclear RNA exosome for intronless mRNA decay

Mure, F., Corbin, A., Benbahouche, N. E. H., Bertrand, E., Manet, E., & Gruffat, H. (2018) · Scientific Reports · doi:10.1038/s41598-018-31078-1 · Cited by 38

Degradation of Non-coding RNAs Promotes Recycling of Termination Factors at Sites of Transcription

Villa, T., Barucco, M., Martin-Niclos, M.-J., Jacquier, A., & Libri, D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107942 · Cited by 37

Substrate specificity of the TRAMP nuclear surveillance complexes

Delan-Forino, C., Spanos, C., Rappsilber, J., & Tollervey, D. (2020) · Nature Communications · doi:10.1038/s41467-020-16965-4 · Cited by 36

Mutations of EXOSC3/Rrp40p associated with neurological diseases impact ribosomal RNA processing functions of the exosome in S. cerevisiae

Gillespie, A., Gabunilas, J., Jen, J. C., & Chanfreau, G. F. (2017) · RNA · doi:10.1261/rna.060004.116 · Cited by 35

In vivo characterization of the critical interaction between the RNA exosome and the essential RNA helicase Mtr4 in Saccharomyces cerevisiae

Sterrett, M. C., Farchi, D., Strassler, S. E., Boise, L. H., Fasken, M. B., & Corbett, A. H. (2023) · G3: Genes, Genomes, Genetics · doi:10.1093/g3journal/jkad049 · Cited by 5