Structure of the Protein Phosphatase 2A Holoenzyme

Xu, Yanhui, Xing, Yongna, Chen, Yu, Chao, Yang, Lin, Zheng, Fan, Eugene, Yu, Jong W., Strack, Stefan +2 more·2006·Cell

DOI 10.1016/j.cell.2006.11.033

Cited by (450)

Items 101–200 of 450

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The phosphoprotein phosphatase family of Ser/Thr phosphatases as principal targets of naturally occurring toxins
Susana R. Pereira, Vitor Manuel Vasconcelos, Agostinho Antunes · 2011 · Critical Reviews in Toxicology
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Thomas McAvoy, Angus Clark Nairn · 2010 · Current Protocols in Molecular Biology
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Deepak Nagendra, James J. Burke, George Larry Maxwell, John Ian Risinger · 2011 · Molecular Carcinogenesis
Protein Phosphatase 2A as a Potential Target for Anticancer Therapy
Peter Kalev, Anna A. Sablina · 2011 · Anti-Cancer Agents in Medicinal Chemistry
PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates
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PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury
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A Novel Epac-Rap-PP2A Signaling Module Controls cAMP-dependent Akt Regulation
Kyoungja Hong, Liguang Lou, Sandhya Gupta, Fernando Ribeiro-Neto, Daniel L. Altschuler · 2008 · Journal of Biological Chemistry
Functions of B56-containing PP2As in major developmental and cancer signaling pathways
Jing Yang, Christopher J. Phiel · 2010 · Life Sciences
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The N Terminus Controls Sterol Binding while the C Terminus Regulates the Scaffolding Function of OSBP
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Regulation of protein phosphatase 2A (PP2A) tumor suppressor function by PME-1
Amanpreet Kaur, Jukka K. Westermarck · 2016 · Biochemical Society Transactions
Assembly and structure of protein phosphatase 2A
Yigong Shi · 2009 · Science in China Series C Life Sciences
Ligand Binding to the Androgen Receptor Induces Conformational Changes That Regulate Phosphatase Interactions
Yang, Chun-Song, Xin, Hong-Wu, Kelley, Joshua B., Spencer, Adam, Brautigan, David L., Paschal, Bryce M. · 2007 · Molecular and Cellular Biology
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Protein Phosphatase-2A Is a Target of Epigallocatechin-3-Gallate and Modulates p53-Bak Apoptotic Pathway
Jichao Qin, He-Ge Chen, Qin Yan, Mi Deng, Jinping Liu, Stephan Doerge, Weiya Ma, Zigang Dong, David Wan-Cheng Li · 2008 · Cancer Research
Regulation of nuclear–cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt
Zhigang Jin, Jin Wei Chung, Wenyan Mei, Stefan Strack, Chunyan He, Gee W. Lau, Jing Yang · 2015 · Molecular Biology of the Cell
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Wang, Xinru, Garvanska, Dimitriya H, Nasa, Isha, Ueki, Yumi, Zhang, Gang, Kettenbach, Arminja N, Peti, Wolfgang, Nilsson, Jakob, Page, Rebecca · 2020 · eLife
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Huawen Lin, Michelle L. Miller, David M. Granas, Susan K. Dutcher · 2013 · PLoS Genetics
Redox inhibition of protein phosphatase PP2A: Potential implications in oncogenesis and its progression
Deepika Raman, Shazib Pervaiz · 2019 · Redox Biology
LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition
Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hao-yun Hsiao et al. · 2019 · Cell Research
PP2A Phosphatase Acts upon SAS-5 to Ensure Centriole Formation in C. elegans Embryos
Daiju Kitagawa, Isabelle Flückiger, Jolanta Polanowska, Debora Keller, Jérôme Reboul, Pierre Gönczy · 2011 · Developmental Cell
Diversity in subcellular targeting of the PP2A B′η subfamily members
Polina R. Matre, Christian Meyer, Cathrine Lillo · 2009 · Planta
Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice
Ortega-Gutiérrez, Silvia, Leung, Donmienne, Ficarro, Scott, Peters, Eric C., Cravatt, Benjamin F. · 2008 · PLoS ONE
A B56γ mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A
Geoffrey Shouse, Yumiko Nobumori, X Liu · 2010 · Oncogene
Protein Phosphatase 2A Is Regulated by Protein Kinase Cα (PKCα)-dependent Phosphorylation of Its Targeting Subunit B56α at Ser41
Uwe Kirchhefer, Alexander Heinick, Simone König, Torsten Kristensen, Frank U. Müller, Matthias Dodo Seidl, Peter Boknı́k · 2013 · Journal of Biological Chemistry
Methylation-regulated decommissioning of multimeric PP2A complexes
Wu, Cheng-Guo, Zheng, Aiping, Jiang, Li, Rowse, Michael, Stanevich, Vitali, Chen, Hui, Li, Yitong, Satyshur, Kenneth A., Johnson, Benjamin, Gu, Ting-Jia et al. · 2017 · Nature Communications
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Lisa Lenaerts, Sara Reynhout, Iris Verbinnen, Frédéric Laumonnier, Annick Toutain, Frédérique Bonnet‐Brilhault, Yana Hoorne, Shelagh K. Joss, Anna Chassevent, Constance L. Smith‐Hicks et al. · 2020 · Genetics in Medicine
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Godfrey Grech, Shawn Baldacchino, Christian Saliba, Maria Pia Grixti, Robert Gauci, Vanessa Petroni Magri, Anthony George Fenech, Christian A. Scerri · 2016 · Tumor Biology
PKR Regulates B56α-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells
Ruvolo, Vivian R., Kurinna, Svitlana M., Karanjeet, Kul B., Schuster, Todd F., Martelli, Alberto M., McCubrey, James A., Ruvolo, Peter P. · 2008 · Journal of Biological Chemistry
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Qinhui Rao, Mengjie Liu, Yuan Tian, Zihan Wu, H. Wang, J. Wang, Y. Xu · 2017 · Worldwide Protein Data Bank
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Arit Ghosh, Jacqueline A. Servin, Gyungsoon Park, Katherine A. Borkovich · 2013 · G3 Genes Genomes Genetics
A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells
Karl William Staser, Matthew A. Shew, Elizabeth G. Michels, Muithi Mwanthi, Feng‐Chun Yang, D. Wade Clapp, Su-Jung Park · 2012 · Experimental Hematology
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Emily H. Rubinson, Audrey H. Metz, Jami O'Quin, Brandt F. Eichman · 2008 · Journal of Molecular Biology
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Susanne A. Kassube, Nicolas H. Thomä · 2020 · Nature Structural & Molecular Biology
Interaction of the Hippo Pathway and Phosphatases in Tumorigenesis
Sahar Sarmasti Emami, Derek Zhang, Xiaolong Yang · 2020 · Cancers
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Liu, L., Eisenman, R. N. · 2012 · Genes & Cancer
TGF-β signaling regulates p-Akt levels via PP2A during diapause entry in the cotton bollworm, Helicoverpa armigera
Haiyin Li, Tao Wang, Yong-Pan Yang, Shao‐Lei Geng, Wei‐Hua Xu · 2017 · Insect Biochemistry and Molecular Biology
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Saraf, Amit, Oberg, Elizabeth A., Strack, Stefan · 2010 · Biochemistry
Selective Proteasomal Degradation of the B′β Subunit of Protein Phosphatase 2A by the E3 Ubiquitin Ligase Adaptor Kelch-like 15
Elizabeth A. Oberg, Shanna K. Nifoussi, Anne‐Claude Gingras, Stefan Strack · 2012 · Journal of Biological Chemistry
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Silvia Marina País, Marina Alejandra González Besteiro, Marı́a Teresa Téllez-Iñón, Daniela Andrea Capiati · 2009 · Planta
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Somy Yoon, Taewon Kook, Hyun-Ki Min, Duk‐Hwa Kwon, Young Kuk Cho, Mi‐Ra Kim, Sera Shin, Hosouk Joung, Seung Hoon Jeong, Sumin Lee et al. · 2018 · Experimental & Molecular Medicine
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Hai Zheng, Qianwei Jin, Xinxin Wang, Yilun Qi, Weida Liu, Yulei Ren, Dan Zhao, Fei Chen, Jingdong Cheng, Xizi Chen et al. · 2023 · Protein & Cell
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ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3 (Mast 3 kinase)
Andrade, Erika C., Musante, Veronica, Horiuchi, Atsuko, Matsuzaki, Hideo, Brody, A. Harrison, Wu, Terence, Greengard, Paul, Taylor, Jane R., Nairn, Angus C. · 2017 · The Journal of Neuroscience
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Sui-Yang Li, C. Brignole, R. Marcellus, S. Thirlwell, O. Binda, M. McQuoid, D. Ashby, Helen L. B. Chan, Zhiying Zhang, Marie-Joëlle Miron et al. · 2009 · Journal of Virology
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Ting-Yuan Lee, Tai-Yu Lai, Shin-Chih Lin, Cheng-Wei Wu, In-Fan Ni, Yu-San Yang, Liang‐Yi Hung, Brian Keith Law, Chi-Wu Chiang · 2010 · Journal of Biological Chemistry
Endotoxin Conditioning Induces VCP/p97-mediated and Inducible Nitric-oxide Synthase-dependent Tyr284 Nitration in Protein Phosphatase 2A
Takashi Ohama, David L. Brautigan · 2010 · Journal of Biological Chemistry
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Fred Kippert, Dietlind L. Gerloff · 2009 · PLoS ONE
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