The Mammalian Epigenome

Bernstein, Bradley E., Meissner, Alexander, Lander, Eric S.·2007·Cell

DOI 10.1016/j.cell.2007.01.033

Cited by (1,004)

Items 401–500 of 1,004

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RNA-directed DNA methylation induces transcriptional activation in plants
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Glucocorticoids regulate natural killer cell function epigenetically
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Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis
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Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic–Mediating Machinery
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The role of hydrogen sulfide in aging and age-related pathologies
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HDAC inhibitors as epigenetic regulators for cancer immunotherapy
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Predicting Functional Effects of Synonymous Variants: A Systematic Review and Perspectives
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Histone H3K4 demethylases are essential in development and differentiationThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
Elizaveta V. Benevolenskaya · 2007 · Biochemistry and Cell Biology
Epigenetic regulation in neural crest development
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Screening for Inhibitors of Low-Affinity Epigenetic Peptide-Protein Interactions: An AlphaScreen™-Based Assay for Antagonists of Methyl-Lysine Binding Proteins
Tim J. Wigle, J. Martin Herold, Guillermo A. Senisterra, Masoud Vedadi, Dmitri Kireev, C.H. Arrowsmith, Stephen V. Frye, William P. Janzen · 2009 · SLAS DISCOVERY
Epigenetics of the vascular endothelium
Matthew Shu-Ching Yan, Charles Christian Matouk, Philip A. Marsden · 2010 · Journal of Applied Physiology
Down syndrome: Neurobiological alterations and therapeutic targets
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Viral epigenomes in human tumorigenesis
Agustín F. Fernández, Manel Esteller · 2010 · Oncogene
The Functional Analysis of Histone Acetyltransferase MOF in Tumorigenesis
Jiaming Su, Fei Wang, Yong Cai, Jingji Jin · 2016 · International Journal of Molecular Sciences
High Resolution Methylome Map of Rat Indicates Role of Intragenic DNA Methylation in Identification of Coding Region
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Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
Peggy Prickaerts, Michiel E. Adriaens, Twan van den Beucken, Elizabeth Koch, Ludwig Jerome Dubois, Vivian E.H. Dahlmans, Caroline M.M. Gits, Chris T. Evelo, Michelle Chan‐Seng‐Yue, Bradly G. Wouters et al. · 2016 · Epigenetics & Chromatin
Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors
Jinmi Choi, Hyonchol Jang, Hyunsoo Kim, Seong‐Tae Kim, Eun‐Jung Cho, Hong‐Duk Youn · 2010 · Biochemical and Biophysical Research Communications
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Claudio D’Addario, Andrea Di Francesco, Mariangela Pucci, Alessandro Finazzi‐Agrò, Mauro Maccarrone · 2013 · FEBS Journal
Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines
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Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq
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High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum
Hehuang Xie, Min Wang, Maria F. Bonaldo, Christina Smith, Veena Rajaram, Stewart Goldman, Tadanori Tomita, Marcelo B. Soares · 2009 · Nucleic Acids Research
Jumonji domain-containing protein 3 regulates histone 3 lysine 27 methylation during bovine preimplantation development
Sebastián Cánovas, Jose Bernardo Cibelli, Pablo J. Ross · 2012 · Proceedings of the National Academy of Sciences
MicroRNA-124a Is Epigenetically Regulated and Acts as a Tumor Suppressor by Controlling Multiple Targets in Uveal Melanoma
Xiaoyan Chen, Dandan He, Xiang Da Dong, Feng Dong, Jiao Wang, Lihua Wang, Jiang Tang, Dan‐Ning Hu, Dongsheng Yan, LiLi Tu · 2013 · Investigative Ophthalmology & Visual Science
Epigenetic changes in diabetes
Samuel T. Keating, Assam El‐Osta · 2013 · Clinical Genetics
Skin Cancer: New Markers for Better Prevention
R. Greinert · 2009 · Pathobiology
Epigenetic Memory in Mammals
Zoë Migicovsky, Igor Kovalchuk · 2011 · Frontiers in Genetics
Core-binding factor β and Runx transcription factors promote adaptive natural killer cell responses
Moritz Rapp, Colleen M. Lau, Nicholas M. Adams, Orr-El Weizman, Timothy Edward O’Sullivan, Clair D. Geary, Joseph Chai-Yuen Sun · 2017 · Science Immunology
The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves
Ilana Janowitz Koch, Michelle M. Clark, Michael J. Thompson, Kerry A Deere, Jun Wang, Lionel Duarte, Gitanjali E. Gnanadesikan, Eskender L. McCoy, Liudmilla Rubbi, Daniel R. Stahler et al. · 2015 · Molecular Ecology
Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition
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Dissecting the Interplay Mechanism between Epigenetics and Gut Microbiota: Health Maintenance and Disease Prevention
Yuqi Wu, Chong‐Zhi Wang, Jin‐Yi Wan, Haiqiang Yao, Chun‐Su Yuan · 2021 · International Journal of Molecular Sciences
Histone Deacetylase Inhibitors through Click Chemistry
Jie Shen, Robert Woodward, James Kedenburg, Xian‐Wei Liu, Min Chen, Lanyan Fang, Duxin Sun, Peng George Wang · 2008 · Journal of Medicinal Chemistry
Fluorous‐Based Small‐Molecule Microarrays for the Discovery of Histone Deacetylase Inhibitors
Arturo J. Vegas, James E. Bradner, Weiping Tang, Olivia M. McPherson, Edward F. Greenberg, Angela N. Koehler, Stuart L. Schreiber · 2007 · Angewandte Chemie International Edition
Role of S-adenosylhomocysteine in cardiovascular disease and its potential epigenetic mechanism
Yunjun Xiao, Xuefen Su, Wei Hsuan Huang, Jinzhou Zhang, Chaoqiong Peng, Haixiong Huang, Xiaomin Wu, Haiyan Huang, Min Xia, Wenhua Ling · 2015 · The International Journal of Biochemistry & Cell Biology
DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss‐of‐function variants
Ziyab, A.H., Karmaus, W., Holloway, J.W., Zhang, H, Ewart, S., Arshad, S.H. · 2013 · Journal of the European Academy of Dermatology and Venereology
Chromatin state maps: new technologies, new insights
Eric M. Mendenhall, B Bernstein · 2008 · Current Opinion in Genetics & Development
Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events
Steve Flanagin, Joel D. Nelson, David G. Castner, Oleg N. Denisenko, Karol Bomsztyk · 2008 · Nucleic Acids Research
Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
Molly Gale, Joyce Sayegh, Jian Ping Cao, Michael Norcia, Peter C. Gareiss, Denton Hoyer, Jane S. Merkel, Qin Yan · 2016 · Oncotarget
Epigenetics and epigenetic alterations in pancreatic cancer.
Noriyuki Omura, Michael Goggins · 2009 · PubMed Central
Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium–derived mesenchymal stem cells
Yoichi Ezura, Ichiro Sekiya, Hideyuki Koga, Takeshi Muneta, Masaki Noda · 2009 · Arthritis & Rheumatism
Tackling the epigenome: challenges and opportunities for collaboration
John S. Satterlee, Dirk Schübeler, Huck‐Hui Ng · 2010 · Nature Biotechnology
The Gut Microbiota and their Metabolites: Potential Implications for the Host Epigenome
Mona Mischke, Torsten Plösch · 2016 · Advances in experimental medicine and biology
Epigenetics – Potential Contribution to Fetal Programming
John Cummings Mathers, Jill A. McKay · 2009 · Advances in experimental medicine and biology
Epigenetics in autoimmune diseases with focus on type 1 diabetes
Mary N. Dang, Raffaella Buzzetti, Paolo Pozzilli · 2012 · Diabetes/Metabolism Research and Reviews
Physical Exercise and Epigenetic Modulation: Elucidating Intricate Mechanisms
Hélios Pareja-Galeano, Fabián Sanchis‐Gomar, Jose Luis García‐Giménez · 2014 · Sports Medicine
Active DNA demethylation and DNA repair
Christof Niehrs · 2009 · Differentiation
Interactions between epigenetics and metabolism in cancers
Yun, Jihye, Johnson, Jared L., Hanigan, Christin L., Locasale, Jason W. · 2012 · Frontiers in Oncology
Evidence for Transcriptional Activity in the Syncytiotrophoblast of the Human Placenta
Peter Ellery, Tereza Cindrová‐Davies, Eric R. M. Jauniaux, Anne C. Ferguson‐Smith, Graham J. Burton · 2009 · Placenta
Epigenetic Regulation of Hepatic Endoplasmic Reticulum Stress Pathways in the Ethanol-Fed Cystathionine Beta Synthase–Deficient Mouse
Farah Esfandiari, Valentina Medici, Donna H. Wong, Soumia Jose, Maryam Dolatshahi, Eoin P. Quinlivan, Sanjana Dayal, Steven R. Lentz, Hidekazu Tsukamoto, Yue Hua Zhang et al. · 2009 · Hepatology
Phenobarbital Mediates an Epigenetic Switch at the Constitutive Androstane Receptor (CAR) Target Gene Cyp2b10 in the Liver of B6C3F1 Mice
Harri Lempiäinen, Arne Müller, Sarah Brasa, Soon-Siong Teo, Tim C. Roloff, Laurent Morawiec, Natasa Zamurovic, Axel Vicart, Enrico G. Funhoff, Philippe Couttet et al. · 2011 · PLoS ONE
Correlative live and super-resolution imaging reveals the dynamic structure of replication domains
Wanqing Xiang, M. Julia Roberti, Jean-Karim Hèriché, Sébastien Huet, Stephanie Alexander, Jan Ellenberg · 2018 · The Journal of Cell Biology
Histone Modifications and Chromatin Organization in Prostate Cancer
Zhong Chen, Liguo Wang, Qianben Wang, Wei Li · 2010 · Epigenomics
Genome-wide H3K9 Histone Acetylation Profiles Are Altered in Benzopyrene-treated MCF7 Breast Cancer Cells
Bekim Sadiković, Joseph D. Andrews, David M. Carter, J. Wesley Robinson, David I. Rodenhiser · 2007 · Journal of Biological Chemistry
Distinct human papillomavirus type 16 methylomes in cervical cells at different stages of premalignancy
Janet L. Brandsma, Ying Hui Sun, Paul M. Lizardi, David P. Tuck, Daniel A. Zelterman, G. Kenneth Haines, Maritza Martel, Malini Harigopal, Kevin Schofield, Matthew Neapolitano · 2009 · Virology
Ras regulation of DNA-methylation and cancer
Samir Kumar Patra · 2008 · Experimental Cell Research
MiRNAs, epigenetics, and cancer
A. MAUREEN ROUHI, Dixie L. Mager, R. Keith Humphries, Florian C. Kuchenbauer · 2008 · Mammalian Genome
Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells
Héctor Hernández‐Vargas, Maria Ouzounova, Florence Le Calvez‐Kelm, Marie-Pierre Lambert, Sandrine McKay‐Chopin, Sean V. Tavtigian, Alain Puisieux, Chantal Matar, Zdenko Herceg · 2011 · Epigenetics
Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction
Rudolf P. Talens, J. Wouter Jukema, Stella Trompet, Dennis Kremer, Rudi G. J. Westendorp, Lambert H. Lumey, Naveed A. Sattar, Hein Putter, P. Eline Slagboom, Bastiaan T. Heijmans · 2011 · International Journal of Epidemiology
Spatiotemporal clustering of the epigenome reveals rules of dynamic gene regulation
Pengfei Yu, Shu Dong XIAO, Xiaoyun Xin, Chun‐Xiao Song, Wei Huang, Darina McDee, Tetsuya S. Tanaka, Ting Wang, Chuan He, Sheng Zhong · 2012 · Genome Research
Spreading Chromatin into Chemical Biology
C. David Allis, Tom W. Muir · 2011 · ChemBioChem
Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation
Martyna Podobińska, Ilona Szabłowska‐Gadomska, Justyna Augustyniak, Ioanna Sandvig, Axel Sandvig, Leonora Bużańska · 2017 · Frontiers in Cellular Neuroscience
The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium
Alejandra Monserrat Retis-Resendiz, Ixchel Nayeli González-García, Moisés León‐Juárez, Ignacio Camacho‐Arroyo, Marco Antonio Cerbón, Edgar Ricardo Vázquez-Martínez · 2021 · Clinical Epigenetics
Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling
Feng Liu, Paul S. Mischel, Webster K. Cavenee · 2017 · npj Precision Oncology
Epigenomic Alterations in Localized and Advanced Prostate Cancer
Pei‐Chun Lin, Ευγενία Γιαννοπούλου, Kyung Park, Juan Miguel Mosquera, Andrea Sboner, Ashutosh Kumar Tewari, Levi A. Garraway, Himisha Beltran, Mark A. Rubin, Olivier Elemento · 2013 · Neoplasia
Epigenome Sequencing Comes of Age
Jian‐Kang Zhu · 2008 · Cell
Epigenetics: a new mechanism of regulation of heart failure?
Roberto Papait, Carolina M. Greco, Paolo Kunderfranco, Michael V.G. Latronico, Gianluigi Condorelli · 2013 · Basic Research in Cardiology
Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control
Sophie A. Lelièvre · 2009 · Biochimica et Biophysica Acta (BBA) - General Subjects
Epigenetics and Obesity
Reinhard J. Stöger · 2008 · Pharmacogenomics
Cancer therapy and vaccination
Hamdy A.A. Aly · 2012 · Journal of Immunological Methods
Tissue-specific demethylation in CpG-poor promoters during cellular differentiation
Genta Nagae, Takayuki Isagawa, Nobuaki Shiraki, Takanori Fujita, Shogo Yamamoto, Shuichi Tsutsumi, Aya Nonaka, Sayaka Yoshiba, Keisuke Matsusaka, Yutaka Midorikawa et al. · 2011 · Human Molecular Genetics
Locking the genome: nuclear organization and cell fate
Peter Meister, Susan E. Mango, Susan M. Gasser · 2011 · Current Opinion in Genetics & Development
Occurrence of DNA methylation in Daphnia magna and influence of multigeneration Cd exposure
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Distinguishing epigenetic marks of developmental and imprinting regulation
Kirsten R. McEwen, Anne C. Ferguson‐Smith · 2010 · Epigenetics & Chromatin
BRG1 Increases Transcription of Proinflammatory Genes in Renal Ischemia
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Targeting epigenetic regulations in cancer
Bo Ning, Wenyuan Li, Wei Zhao, Rong‐Fu Wang · 2015 · Acta Biochimica et Biophysica Sinica
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The key culprit in the pathogenesis of systemic lupus erythematosus: Aberrant DNA methylation
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Methylation and transcriptome analysis reveal lung adenocarcinoma-specific diagnostic biomarkers
Rui Li, Yie Yang, Yunhong Yin, Mengyu Zhang, Hao Li, Yi-Qing Qu · 2019 · Journal of Translational Medicine
Epigenetic regulation in lung cancer
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Three-Dimensional Collagen I Promotes Gemcitabine Resistance In Vitro in Pancreatic Cancer Cells through HMGA2-Dependent Histone Acetyltransferase Expression
Surabhi Y. Dangi-Garimella, Vaibhav Sahai, Kazumi Ebine, Krishan Kumar, Hidayatullah G. Munshi · 2013 · PLoS ONE
Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes
Amanda J MacFarlane, Alexander Strom, Fraser W. Scott · 2009 · Mammalian Genome
Immunometabolism orchestrates training of innate immunity in atherosclerosis
Julia van Tuijl, Leo A. B. Joosten, Mihai Gheorghe Netea, Siroon Bekkering, Niels Peter Riksen · 2019 · Cardiovascular Research
The emerging roles of PIWI-interacting RNA in human cancers
Yaya Yu, Jing Xiao, Swei Sunny Hann · 2019 · Cancer Management and Research
The Pathogenic Role of Dysregulated Epigenetic Modifications in Autoimmune Diseases
Haijing Wu, Yongjian Chen, Huan Zhu, Ming Zhao, Qianjin Lu · 2019 · Frontiers in Immunology
Epigenetic Control of Mitochondrial Function in the Vasculature
S A Mohammed, Samuele Ambrosini, Thomas Felix Lüscher, Francesco Paneni, Sarah Costantino · 2020 · Frontiers in Cardiovascular Medicine
Analysis of chromatin-state plasticity identifies cell-type–specific regulators of H3K27me3 patterns
Luca Pinello, Jian Xu, Stuart H. Orkin, Guo‐Cheng Yuan · 2014 · Proceedings of the National Academy of Sciences
MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells
Marlinda Hupkes, Ana M. Sotoca, José M. A. Hendriks, E.J.J. van Zoelen, Koen J. Dechering · 2014 · BMC Molecular Biology
Should I stay or should I go: Protection and maintenance of DNA methylation at imprinted genes
Daniel M. Messerschmidt · 2012 · Epigenetics
A review of the genetic and epigenetic factors affecting lamb survival
F. D. Brien, Schalk W.P. Cloete, N. M. Fogarty, J. C. Greeff, M. L. Hebart, Stefan Hiendleder, Janelle E. Hocking Edwards, Jennifer M. Kelly, Karen L. Kind, David O. Kleemann et al. · 2014 · Animal Production Science
The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development
Nao Suzki, Yusuke Hirabayashi, Kelsey M. Tyssowski, Jun Shinga, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh · 2014 · Development
Nucleation of DNA repair factors by FOXA1 links DNA demethylation to transcriptional pioneering
Yu Zhang, Di Zhang, Qian Li, Jing Liang, Luyang Sun, Xia Yi, Zhe Chen, Ruorong Yan, Guojia Xie, Wanjin Li et al. · 2016 · Nature Genetics
Hydroxymethylation of DNA: an epigenetic marker.
Rajneesh Richa, Rajeshwar Prasad Sinha · 2014 · Europe PMC (PubMed Central)
Preconception folic acid supplementation and risk for chromosome 21 nondisjunction: A report from the National Down Syndrome Project
NaTasha D. Hollis, Emily Graves Allen, Tiffany Renee Oliver, Stuart W. Tinker, Charlotte M. Druschel, Charlotte A. Hobbs, Leslie A. O’Leary, Paul A. Romitti, Marjorie H. Royle, Claudine P. Torfs et al. · 2013 · American Journal of Medical Genetics Part A
The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein
Capucine Van Rechem, Joshua C. Black, Tarek Abbas, Andrew Allen, Claire A. Rinehart, Guo‐Cheng Yuan, Anindya Dutta, Johnathan R. Whetstine · 2011 · Journal of Biological Chemistry
Histone modifications: crucial elements for damage response and chromatin restoration
Qianzheng Zhu, Altaf A. Wani · 2010 · Journal of Cellular Physiology
Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response
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Identification of a Functional Network of Human Epigenetic Silencing Factors
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