Hypoxia-Inducible Factors, Stem Cells, and Cancer
Keith, Brian, Simon, M. Celeste·2007·Cell
Cited by (1,000)
Items 401–500 of 1,000
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- Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cellsYawara Kawano, Yoshitaka Kikukawa, Shiho Fujiwara, Naoko A. Wada, Yutaka Okuno, Hiroaki Mitsuya, Hiroyuki Hata · 2013 · International Journal of Oncology
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- HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradationLavinia Nardinocchi, Rosa Puca, Gabriella D’Orazi · 2011 · Aging
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- PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of Colorectal Cancer Cells under Simulated MicrogravityRaj Pranap Arun, Divya Sivanesan, Prasanna Vidyasekar, Rama Shanker Verma · 2017 · Scientific Reports
- The standardized Korean Red Ginseng extract and its ingredient ginsenoside Rg3 inhibit manifestation of breast cancer stem cell–like properties through modulation of self-renewal signalingJisun Oh, Hyo‐Jin Yoon, Jeong‐Hoon Jang, Do‐Hee Kim, Young‐Joon Surh · 2018 · Journal of Ginseng Research
- Regulatory Role of Quiescence in the Biological Function of Cancer Stem CellsSau Har Lee, Tamika C. Reed-Newman, Shrikant Anant, Thamil Selvee Ramasamy · 2020 · Stem Cell Reviews and Reports
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- bHLH-Orange Transcription Factors in Development and CancerHong Sun, Saghi Ghaffari, Reshma Taneja · 2007 · Translational Oncogenomics
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- Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden: Impact on cancer immunotherapyRaefa Abou Khouzam, Bassam Janji, Jérôme Thiery, Rania Faouzi Zaarour, Ali N. Chamseddine, Hemma Mayr, Pierre Savagner, Claudine Kiéda, Sophie Gad, Stéphanie Buart et al. · 2023 · Seminars in Cancer Biology
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- Hypoxia‐mediated CD 24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasionNobuaki Fujikuni, Hideki Yamamoto, Kazuaki Tanabe, Yutaka Naito, Naoya Sakamoto, Yuka Tanaka, Kazuyoshi Yanagihara, Naohide Oue, Wataru Yasui, Hideki Ohdan · 2014 · Cancer Science
- Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor CellsAlbertus T.J. Wierenga, Edo Vellenga, Jan Jacob Schuringa · 2014 · PLoS ONE
- Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactionsLido Calorini, Francesca Bianchini · 2010 · Cell Communication and Signaling
- Hypoxia enhances tenocyte differentiation of adipose‐derived mesenchymal stem cells by inducing hypoxia‐inducible factor‐1α in a co‐culture systemYu Yang, Yulong Zhou, Tao Cheng, Xiaolang Lu, Kehe Yu, Yifei Zhou, Jianjun Hong, Ying Grace Chen · 2016 · Cell Proliferation
- Metastasis risk prediction model in osteosarcoma using metabolic imaging phenotypes: A multivariable radiomics modelHeesoon Sheen, Wook Kim, Byung Hyun Byun, Chang‐Bae Kong, Won Seok Song, Wan Hyeong Cho, Ilhan Lim, Sang Moo Lim, Sang‐Keun Woo · 2019 · PLoS ONE
- m6A-express: uncovering complex and condition-specific m6A regulation of gene expressionTeng Zhang, Shao‐Wu Zhang, Song-Yao Zhang, Shou‐Jiang Gao, Yidong Chen, Yufei Huang · 2021 · Nucleic Acids Research
- LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressorYijun Gao, Gaoxiang Ge, Hongbin Ji · 2011 · Protein & Cell
- A tumor hypoxic niche protects human colon cancer stem cells from chemotherapyQin Mao, Yu Zhang, Xiaoyue Fu, Jianxin Xue, Wenhao Guo, Maobing Meng, Zong‐Guang Zhou, Xianming Mo, You Lü · 2012 · Journal of Cancer Research and Clinical Oncology
- Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancerJung Ho Kim · 2015 · World Journal of Gastroenterology
- EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLCRuyang Zhang, Linjing Lai, Jieyu He, Chao Chen, Dongfang You, Weiwei Duan, Xuesi Dong, Ying Zhu, Lijuan Lin, Sipeng Shen et al. · 2019 · Epigenetics
- The Tumor Microenvironment and DNA RepairThomas J. Klein, Peter M. Glazer · 2010 · Seminars in Radiation Oncology
- Pharmacological HIF2α inhibition improves VHL disease–associated phenotypes in zebrafish modelAna Martins Metelo, Haley R. Noonan, Xiang Li, Youngnam N. Jin, Rania Baker, Lee D. Kamentsky, Yiyun Zhang, Ellen van Rooijen, Jordan T. Shin, Anne Elizabeth Carpenter et al. · 2015 · Journal of Clinical Investigation
- Influence of electrospun fiber mesh size on hMSC oxygen metabolism in 3D collagen matrices: Experimental and theoretical evidencesAngela Guaccio, Vincenzo Guarino, Marco A. Alvarez‐ Perez, Valentina Cirillo, Paolo A. Netti, Luigi Ambrosio · 2011 · Biotechnology and Bioengineering
- Plasmonic Particles that Hit Hypoxic CellsFulvio Ratto, Ewa J. Witort, Francesca Tatini, Sonia Centi, Lorenza Lazzeri, Fabrizio Carta, Matteo Lulli, Daniela Vullo, Franco Fusi, Claudiu Trandafir Supuran et al. · 2014 · Advanced Functional Materials
- High Oxygen Condition Facilitates the Differentiation of Mouse and Human Pluripotent Stem Cells into Pancreatic Progenitors and Insulin-producing Cells*Farzana Hakim, T. Kaitsuka, Jamiruddin Mohd Raeed, Fan-Yan Wei, Nobuaki Shiraki, Tadayuki Akagi, T. Yokota, S. Kume, K. Tomizawa · 2014 · Journal of Biological Chemistry
- HIF-1α Transgenic Bone Marrow Cells Can Promote Tissue Repair in Cases of Corticosteroid-Induced Osteonecrosis of the Femoral Head in RabbitsHao Ding, Youshui Gao, Hu Chen, Yang Wang, Chuangui Wang, Jimin Yin, Yuan Sun, Changqing Zhang · 2013 · PLoS ONE
- Cathepsin L in tumor angiogenesis and its therapeutic intervention by the small molecule inhibitor KGP94Dhivya R. Sudhan, María Belén Rabaglino, Charles E. Wood, Dietmar W. Siemann · 2016 · Clinical & Experimental Metastasis
- Vasorin stimulates malignant progression and angiogenesis in gliomaWeiye Liang, Baoyin Guo, Jiecheng Ye, Hui Liu, Wanying Deng, Chenli Lin, Xueyun Zhong, Lihui Wang · 2019 · Cancer Science
- The Roles of Hypoxia Imaging Using 18F-Fluoromisonidazole Positron Emission Tomography in Glioma TreatmentKenji Hirata, Shigeru Yamaguchi, Tohru Shiga, Yuji Kuge, Nagara Tamaki · 2019 · Journal of Clinical Medicine
- Role of Tumor Microenvironment in Cancer Stem Cells Resistance to RadiotherapyShahram Taeb, Milad Ashrafizadeh, Ali Zarrabi, Saeed Rezapoor, Ahmed Eleojo Musa, Bagher Farhood, Masoud Najafi · 2021 · Current Cancer Drug Targets
- Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancerVelletri, Tania, Villa, Carlo Emanuele, Cilli, Domenica, Barzaghi, Bianca, Lo Riso, Pietro, Lupia, Michela, Luongo, Raffaele, López-Tobón, Alejandro, De Simone, Marco, Bonnal, Raoul J. P. et al. · 2022 · Cell Death & Differentiation
- The Functional Role of Notch Signaling in Triple-Negative Breast CancerJodi J. Speiser, Çağatay H. Erşahin, Clodia Osipo · 2013 · Vitamins and hormones
- mir-210: A Sensor for Hypoxic Stress during TumorigenesisLijoy K. Mathew, Marie Celeste Simon · 2009 · Molecular Cell
- Vasculogenic Mimicry of HT1080 Tumour Cells In Vivo: Critical Role of HIF-1α-Neuropilin-1 AxisRoli M. Misra, Manmohan S. Bajaj, Vaijayanti Prakash Kale · 2012 · PLoS ONE
- In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative MedicineKyung Min Park, Ki Dong Park · 2018 · Tissue Engineering and Regenerative Medicine
- Nutritional stress reprograms dedifferention in glioblastoma multiforme driven by PTEN/Wnt/Hedgehog axis: a stochastic model of cancer stem cellsSusmita Mondal, Kaushik Bhattacharya, Chitra Mandal · 2018 · Cell Death Discovery
- Basic Biology of Hypoxic Responses Mediated by the Transcription Factor HIFs and Its Implication for MedicineKiichi Hirota · 2020 · Biomedicines
- The Design of Dextran‐Based Hypoxia‐Inducible Hydrogels via In Situ Oxygen‐Consuming ReactionKyung Min Park, Michael R. Blatchley, Sharon Gerecht · 2014 · Macromolecular Rapid Communications
- SIRT1/PGC-1α/PPAR-γ Correlate With Hypoxia-Induced Chemoresistance in Non-Small Cell Lung CancerRui Xu, Xin Luo, Xuan Ye, Huan Li, Hongyue Liu, Qiong Du, Qing Zhai · 2021 · Frontiers in Oncology
- Notch signaling, hypoxia, and cancerMingzhou Guo, Yang Niu, Min Xie, Xiansheng Liu, Xiaochen Li · 2023 · Frontiers in Oncology
- Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engineRaymond J. Winquist, Diane M. Boucher, Mark L. Wood, Brinley F. Furey · 2009 · Biochemical Pharmacology
- Beta-Catenin/HuR Post-Transcriptional Machinery Governs Cancer Stem Cell Features in Response to HypoxiaGabriele D’Uva, Sara Bertoni, Mattia Lauriola, Sabrina De Carolis, Annalisa Pacilli, Laura D'Anello, Donatella Santini, Mario Taffurelli, Claudio Ceccarelli, Yosef Yarden et al. · 2013 · PLoS ONE
- Inhibition of intracranial glioma growth by endometrial regenerative cellsXiaodi Han, Xiaolong Meng, Zhenglian Yin, Andrea Rogers, Jie Ming Zhong, P. Rillema, James A. Jackson, Thomas E. Ichim, Boris Minev, Ewa Carrier et al. · 2009 · Cell Cycle
- Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signalingPeng Gao, Chunzhang Yang, Cody L. Nesvick, Michael J. Feldman, Saman Sizdahkhani, Huailei Liu, Huiying Chu, Fengxu Yang, Ling Tang, Jing Tian et al. · 2016 · Oncotarget
- Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft modelPallavi Sontakke, Marco Carretta, Jenny Jaques, Annet Z. Brouwers-Vos, Linda Lubbers-Aalders, Huipin Yuan, Joost Dick de Bruijn, Anton C. Martens, Edo Vellenga, Richard W.J. Groen et al. · 2016 · Leukemia
- The expression of cancer stem cell markers in human colorectal carcinoma cells in a microenvironment dependent mannerVaidotas Stankevičius, Linas Kunigenas, Edvinas Stankunas, Karolina Kuodyte, Eglė Strainienė, Jonas Cicenas, Narimantas Evaldas Samalavičius, Kęstutis Sužiedėlis · 2017 · Biochemical and Biophysical Research Communications
- Two-Dimensional vs. Three-Dimensional In Vitro Tumor Migration and Invasion AssaysMiriam Zimmermann, Carol Box, Suzanne A. Eccles · 2013 · Methods in molecular biology
- Human Pancreatic Cancer Stem Cells: Implications for How We Treat Pancreatic CancerCheong Jun Lee, Chenwei Li, Diane M. Simeone · 2008 · Translational Oncology
- CD133 Modulate HIF-1α Expression under Hypoxia in EMT Phenotype Pancreatic Cancer Stem-Like CellsKoki Maeda, Qiang Ding, Makoto Yoshimitsu, Taisaku Kuwahata, Yumi Miyazaki, Koichirou Tsukasa, Tomomi Hayashi, Hiroyuki Shinchi, Shoji Natsugoe, Sonshin Takao · 2016 · International Journal of Molecular Sciences
- CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cellsJunlan Zhu, Grace Huang, Xiaohui Hua, Yang Li, Huiying Yan, Xun Che, Zhongxian Tian, Huating Liufu, Chao Huang, Jingxia Li et al. · 2019 · Oncogene
- Metabolic regulation of the bone marrow microenvironment in leukemiaBinyan Xu, Rong Hu, Liang Zhao, Tong Chen, Jianyu Chen, Yuxing Hu, Yirong Jiang, Yuhua Li · 2020 · Blood Reviews
- Stem Cells in Cancer: From Mechanisms to Therapeutic StrategiesLaurence Haddadin, Xueqin Sherine Sun · 2025 · Cells
- Targeting the N otch signaling pathway in cancer therapeuticsHuajiao Guo, Yi Lü, Jianhua Wang, Xia Liu, Evan T. Keller, Qian Liu, Qinghua Zhou, Jian Zhang · 2014 · Thoracic Cancer
- The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viabilityBryan L. Krock, T.S. Karin Eisinger‐Mathason, Dionysios N. Giannoukos, Jessica E.S. Shay, Mercy Gohil, David S.M. Lee, Michael S. Nakazawa, Julie Sesen, Nicolas Skuli, Marie Celeste Simon · 2015 · Blood
- Enhanced Photodynamic Therapy and Effective Elimination of Cancer Stem Cells Using Surfactant–Polymer NanoparticlesМ. Н. Усачева, Suresh Kumar Swaminathan, Ameya R. Kirtane, Jayanth Panyam · 2014 · Molecular Pharmaceutics
- Clinical characteristics and preliminary morphological observation of 47 cases of primary anorectal malignant melanomasGuang Liu, Yan Wang, Fei Fei, Xinlu Wang, Chunyuan Li, Kai Liu, Jiaxiang Du, Yuan Cao, Shiwu Zhang · 2018 · Melanoma Research
- Hypoxia re-programs 2′-O-Me modifications on ribosomal RNABrandon J. Metge, Sarah C. Kammerud, Hawley C. Pruitt, Lalita A. Shevde, Rajeev S. Samant · 2020 · iScience
- HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathwayKang Lai Tang, Takeshi Toyozumi, Kentaro Murakami, Haruhito Sakata, Masayuki Kano, Satoshi Endo, Yasunori Matsumoto, Hiroshi Suito, Masahīko Takahashi, Nobufumi Sekino et al. · 2022 · British Journal of Cancer
- The Role of the Hypoxia-Related Unfolded Protein Response (UPR) in the Tumor MicroenvironmentBartoszewska, Sylwia, Collawn, James F., Bartoszewski, Rafal · 2022 · Cancers
- An Efficacy and Mechanism Driven Study on the Impact of Hypoxia on Lipid Nanoparticle Mediated mRNA DeliveryYutian Ma, Owen S. Fenton · 2023 · Journal of the American Chemical Society
- Prospective evaluation of angiogenic, hypoxic and EGFR‐related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecanBenedikte Hasselbalch, Jesper Grau Eriksen, Helle Broholm, Ib Jarle Christensen, Kirsten Grunnet, Michael R. Horsman, Hans Skovgaard Poulsen, Marie‐Thérése Stockhausen, Ulrik Lassen · 2010 · Apmis
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- HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cellsAlbertus T.J. Wierenga, Alan Cunningham, Ayşegül Erdem, Nuria Vilaplana‐Lopera, Annet Z. Brouwers-Vos, Maurien G. M. Pruis, André B. Mulder, Ulrich L. Günther, Joost H.A. Martens, Edo Vellenga et al. · 2019 · Cancer & Metabolism
- Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor MicroenvironmentFares Nigim, Jill Cavanaugh, Anoop P. Patel, William T. Curry, Shinichi Esaki, Ekkehard Matthias Kasper, Andrew S. Chi, David N. Louis, Robert L. Martuza, Samuel D. Rabkin et al. · 2015 · Journal of Neuropathology & Experimental Neurology
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- HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII- gene activation under hypoxic conditions in ovarian cancer cellsShiro Koizume, Shin Ito, Etsuko Miyagi, Fumiki Hirahara, Yoshiyasu Nakamura, Yuji Sakuma, Hitoshi Osaka, Yasuo Takano, Wolfram Ruf, Yohei Miyagi · 2012 · Nucleic Acids Research
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- Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signalingMing Yue Li, Chunliu Mi, Ke Si Wang, Zhe Wang, Hong Xiang Zuo, Lian Xun Piao, Guang Hua Xu, Xuezheng Li, Juan Ma, Xuejun Jin · 2017 · Chemico-Biological Interactions
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