Hypoxia-Inducible Factors, Stem Cells, and Cancer
Keith, Brian, Simon, M. Celeste·2007·Cell
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Items 101–200 of 1,000
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- Persistent Regulation of Tumor Hypoxia Microenvironment via a Bioinspired Pt‐Based Oxygen Nanogenerator for Multimodal Imaging‐Guided Synergistic PhototherapyQing You, Kaiyue Zhang, Jingyi Liu, Changliang Liu, Huayi Wang, Mengting Wang, Siyuan Ye, Houqian Gao, Letian Lv, Chen Wang et al. · 2020 · Advanced Science
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- Hypoxia-inducible hydrogelsKyung Min Park, Sharon Gerecht · 2014 · Nature Communications
- Interfering with Tumor Hypoxia for Radiotherapy OptimizationIrma Telarović, Roland H. Wenger, Martin N. Pruschy · 2021 · Journal of Experimental & Clinical Cancer Research
- Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like CellsJianghong Man, Xingjiang Yu, Haidong Huang, Wenchao Zhou, Chaomei Xiang, Haohao Huang, Lucio Miele, Zheng-gang Liu, Gürkan Bebek, Shideng Bao et al. · 2017 · Cell stem cell
- Biophysical models of tumour growthPhilippe Tracqui · 2009 · Reports on Progress in Physics
- Mitochondrial Metabolism Modulates Differentiation and Teratoma Formation Capacity in Mouse Embryonic Stem CellsStefan M. Schieke, Mingchao Ma, Liu Cao, John Philip McCoy, Chengyu Liu, Nancy F. Hensel, A. John Barrett, Manfred Boehm, Toren Finkel · 2008 · Journal of Biological Chemistry
- FOXM1 (Forkhead box M1) in TumorigenesisInken Wierstra · 2013 · Advances in cancer research
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- New wirings in the survivin networksDario C. Altieri · 2008 · Oncogene
- Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune EscapeSalem Chouaı̈b, Yosra Messai, Sophie Couvé, Bernard J. Escudier, Meriem Hasmim, Muhammad Zaeem Noman · 2012 · Frontiers in Immunology
- Nanocarrier cancer therapeutics with functional stimuli-responsive mechanismsNeha Kaushik, Shweta B. Borkar, Sondavid Nandanwar, Pritam Kumar Panda, Eun Ha Choi, Nagendra Kumar Kaushik · 2022 · Journal of Nanobiotechnology
- The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressivenessBin Bao, Asfar Sohail Azmi, Shadan S. Ali, Aamir Ahmad, Yiwei Li, Sanjeev Banerjee, Dejuan Kong, Fazlul H. Sarkar · 2012 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
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- NQO1 inhibits proteasome-mediated degradation of HIF-1αEun‐Taex Oh, Jung‐whan Kim, Joon Mee Kim, Soo‐Jeong Kim, Jae‐Seon Lee, Soon‐Sun Hong, Justin Goodwin, Robin J. Ruthenborg, Myung Gu Jung, Hae‐June Lee et al. · 2016 · Nature Communications
- The Transcription Factor FOXM1 (Forkhead box M1)Inken Wierstra · 2013 · Advances in cancer research
- Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancerDavid J. Stewart · 2010 · Critical Reviews in Oncology/Hematology
- Molecular targeting of hypoxia in radiotherapySergio Rey, Luana Schito, Marianne Koritzinsky, Bradly G. Wouters · 2016 · Advanced Drug Delivery Reviews
- Tumor Heterogeneity: Mechanisms and Bases for a Reliable Application of Molecular Marker DesignSalvador J. Díaz‐Cano · 2012 · International Journal of Molecular Sciences
- Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78Kenichi Miharada, Göran Karlsson, Matilda Rehn, Emma Rörby, Kavitha Siva, Jörg Cammenga, Stefan Karlsson · 2011 · Cell stem cell
- Modulation of the tumor vasculature and oxygenation to improve therapySiemann, Dietmar W., Horsman, Michael R. · 2015 · Pharmacology & Therapeutics
- Cell plasticity, senescence, and quiescence in cancer stem cells: Biological and therapeutic implicationsRitama Paul, Jay F. Dorsey, Yi Fan · 2021 · Pharmacology & Therapeutics
- The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironmentAlina Filatova, Till Acker, Boyan K. Garvalov · 2012 · Biochimica et Biophysica Acta (BBA) - General Subjects
- HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar EpitheliumTobias de la Garza Eckle, Kelley S. Brodsky, Megan Bonney, Thomas Alexander Packard, Jun Han, Christoph H. Borchers, Thomas J. Mariani, Douglas J. Kominsky, Michel Guy André Mittelbronn, Holger K. Eltzschig · 2013 · PLoS Biology
- Empowering self-renewal and differentiation: the role of mitochondria in stem cellsJalees Rehman · 2010 · Journal of Molecular Medicine
- Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cellsNuzhat Ahmed, Ruth M. Escalona, Dilys T.H. Leung, Emily Chan, George Kannourakis · 2018 · Seminars in Cancer Biology
- Starvation, Stress Resistance, and CancerBuono, Roberta, Longo, Valter D. · 2018 · Trends in Endocrinology & Metabolism
- Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxiaBegoña Díaz, Angela Yuen, Shinji Iizuka, Shigeki Higashiyama, Sara A. Courtneidge · 2013 · The Journal of Cell Biology
- HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progressionB. Philip, Koichi Ito, Rafael Moreno‐Sánchez, Stephen John Ralph · 2013 · Carcinogenesis
- Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effectSolinas, Marta, Massi, Paola, Cinquina, Valentina, Valenti, Marta, Bolognini, Daniele, Gariboldi, Marzia, Monti, Elena, Rubino, Tiziana, Parolaro, Daniela · 2013 · PLoS ONE
- Sugar and fat – that's where it's at: metabolic changes in tumorsChristian D. Young, Steven Michael Anderson · 2008 · Breast Cancer Research
- Tumor suppressor functions of FBW7 in cancer development and progressionZhiwei Peter Wang, Hiroyuki Inuzuka, Jiateng Zhong, Lixin Wan, Hidefumi Fukushima, Fazlul H. Sarkar, Wenyi Wei · 2012 · FEBS Letters
- Current Understanding on EGFR and Wnt/ -Catenin Signaling in Glioma and Their Possible CrosstalkIndranil Paul, S. Bhattacharya, A. Chatterjee, Mrinal K. Ghosh · 2013 · Genes & Cancer
- RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survivalViolaine Goidts, Josephine Bageritz, Laura Puccio, Susumu Nakata, Marc Zapatka, Sebastian Barbus, Grischa Toedt, Benito Campos, Andrey Korshunov, Stefan Momma et al. · 2011 · Oncogene
- Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in CancersSiyuan Song, Tania Y. Christova, Stephen J. Perusini, Solmaz Alizadeh, Ren-Yue Bao, Bryan W. Miller, Rose Hurren, Yulia Jitkova, Marcela Gronda, Methvin B. Isaac et al. · 2011 · Cancer Research
- Nitric oxide, apoptosis and macrophage polarization during tumor progressionAndreas Weigert, Bernhard Brüne · 2008 · Nitric Oxide
- CDH5 is specifically activated in glioblastoma stemlike cells and contributes to vasculogenic mimicry induced by hypoxiaXinggang Mao, Xiaoyan Xue, Liang Wang, Xiang Zhang, M. Yan, Y.-y. Tu, W. Lin, Xiaofan Jiang, He Ren, Wei Zhang et al. · 2013 · Neuro-Oncology
- Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic ImplicationsRachel Shi, Chengheng Liao, Qing Hua Zhang · 2021 · Cells
- Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathwaySandra Eliasz, Shuang Liang, Y. Chen, Melissa Arakelian De Marco, O Machek, Sylvia Skucha, Lucio Miele, Maurizio Bocchetta · 2010 · Oncogene
- Hypoxia in solid tumors: a key promoter of cancer stem cell (CSC) resistanceMasoud Najafi, Bagher Farhood, Keywan Mortezaee, Ebrahim Kharazinejad, Jamal Majidpoor, Reza Ahadi · 2019 · Journal of Cancer Research and Clinical Oncology
- Medulloblastoma Stem CellsXing Fan, Charles G. Eberhart · 2008 · Journal of Clinical Oncology
- CoCl2, a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon CancerLaura Maria Lopez-Sanchez, Carla Jimenez, Araceli Maria Valverde, Vanessa A Hernandez, Jon Peñarando, Antonio Martínez-Aranda, Chary López-Pedrera, Juan Rafael Muñoz-Castañeda, Juan de la Haba-Rodríguez, Enrique Aranda et al. · 2014 · PLoS ONE
- Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cellsJane Ru Choi, Belinda Pingguan‐Murphy, Wan Abu Bakar Wan Abas, Mat Adenan Noor Azmi, Siti Zawiah Omar, Kien Hui Chua, Wan Safwani Wan Kamarul Zaman · 2014 · Biochemical and Biophysical Research Communications
- Urothelial carcinoma associated 1 is a hypoxia-inducible factor-1α-targeted long noncoding RNA that enhances hypoxic bladder cancer cell proliferation, migration, and invasionMei Xue, Xu Li, Zhengkun Li, Wei Chen · 2014 · Tumor Biology
- Hypoxia as a biomarker for radioresistant cancer stem cellsClaudia Peitzsch, Rosalind L. Perrin, Richard Peter Hill, Anna Dubrovska, Ina Kurth · 2014 · International Journal of Radiation Biology
- Hypoxia-induced metabolic shifts in cancer cells: Moving beyond the Warburg effectAalim M. Weljie, Frank Robert Jirik · 2010 · The International Journal of Biochemistry & Cell Biology
- Notch1 controls development of the extravillous trophoblast lineage in the human placentaSandra Haider, Gudrun Meinhardt, Leila Saleh, Christian Fiala, Jürgen Pollheimer, Martin Knöfler · 2016 · Proceedings of the National Academy of Sciences
- Mechanisms of resistance to anti-angiogenesis therapiesSandy Giuliano, Gilles Pagès · 2013 · Biochimie
- "Destemming" Cancer Stem CellsRichard Peter Hill, Roberto Perris · 2007 · JNCI Journal of the National Cancer Institute
- Impact of Metabolism in on T-Cell Differentiation and Function and Cross Talk with Tumor MicroenvironmentSoumaya Kouidhi, Amel Benammar Elgaaïed, Salem Chouaı̈b · 2017 · Frontiers in Immunology
- Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling AxisMin-Zu Wu, Su-Feng Chen, Shin Nieh, Christopher W. Benner, Luo‐Ping Ger, Chia‐Ing Jan, Li Ma, Chien‐Hung Chen, Tomoaki Hishida, Hong‐Tai Chang et al. · 2015 · Cancer Research
- Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed CellsShuyang Chen, Nianli Sang · 2015 · Journal of Cellular Biochemistry
- Hypoxia-Inducible Factor-2α Correlates to Distant Recurrence and Poor Outcome in Invasive Breast CancerHelczynska, Karolina, Larsson, Anna-Maria, Holmquist Mengelbier, Linda, Bridges, Esther, Fredlund, Erik, Borgquist, Signe, Landberg, Göran, Påhlman, Sven, Jirström, Karin · 2008 · Cancer Research
- HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cellsPietras, Alexander, Hansford, Loen M., Johnsson, A. Sofie, Bridges, Esther, Sjölund, Jonas, Gisselsson, David, Rehn, Matilda, Beckman, Siv, Noguera, Rosa, Navarro, Samuel et al. · 2009 · Proceedings of the National Academy of Sciences
- An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease ProgressionHiromitsu Hayashi, Takaaki Higashi, Naomi Yokoyama, Takayoshi Kaida, Keita Sakamoto, Yukiko Fukushima, Takatsugu Ishimoto, Hideyuki Kuroki, Hidetoshi Nitta, Daisuke Hashimoto et al. · 2015 · Cancer Research
- Signaling by Hypoxia-Inducible Factors Is Critical for Ovulation In MiceJaeyeon Kim, Indrani C. Bagchi, Milan K. Bagchi · 2009 · Endocrinology
- Nanomedicine-mediated cancer stem cell therapySong Shen, Jinxing Xia, Jun Wang · 2015 · Biomaterials
- Dedifferentiation of Glioma Cells to Glioma Stem-like Cells By Therapeutic Stress-induced HIF Signaling in the Recurrent GBM ModelGina Lee, Brenda Auffinger, Donna Guo, Tanwir Hasan, Marc Deheeger, Alex L. Tobias, Jeong Yeon Kim, Fatemeh Atashi, Lingjiao Zhang, Maciej S. Lesniak et al. · 2016 · Molecular Cancer Therapeutics
- Syndecan-3 and Notch cooperate in regulating adult myogenesisAddolorata Pisconti, DDW Cornelison, Hugo C. Olguín, Tiffany L. Antwine, Bradley B. Olwin · 2010 · The Journal of Cell Biology
- Mechanisms and Consequences of Oxygen and Carbon Dioxide Sensing in MammalsEoin P. Cummins, Moritz J. Strowitzki, Cormac T. Taylor · 2019 · Physiological Reviews
- An essential role for SRC-activated STAT-3 in 14,15-EET–induced VEGF expression and angiogenesisSergey Y. Cheranov, Manjula Karpurapu, Dong Wang, Baolin Zhang, Richard C. Venema, Gadiparthi N. Rao · 2008 · Blood
- Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and EpigeneticsCristina D’Aniello, Federica Cermola, Eduardo Jorge Patriarca, Gabriella Minchiotti · 2017 · Stem Cells International
- CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and MetastasisThomas, Shibu, Harding, Michael A., Smith, Steven C., Overdevest, Jonathan B., Nitz, Matthew D., Frierson, Henry F., Tomlins, Scott A., Kristiansen, Glen, Theodorescu, Dan · 2012 · Cancer Research
- Akt2 Regulates All Akt Isoforms and Promotes Resistance to Hypoxia through Induction of miR-21 upon Oxygen DeprivationChristos Polytarchou, Dimitrios Iliopoulos, Maria Hatziapostolou, Filippos Kottakis, Ioanna G Maroulakou, Kevin Struhl, Philip N. Tsichlis · 2011 · Cancer Research
- Hypoxia‐inducible factors in stem cells and cancerJolly Mazumdar, Vijay R. Dondeti, Marie Celeste Simon · 2009 · Journal of Cellular and Molecular Medicine
- Three‐dimensional cell culture model utilization in cancer stem cell researchZofia Felicja Bielecka, Kamila Maliszewska‐Olejniczak, ILAN J. SAFIR, Cezary A. Szczylik, Anna Malgorzata Czarnecka · 2016 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
- Targeting autophagy in cancer stem cells as an anticancer therapyYuanyuan Lei, Dan Zhang, Jin Yu, Hui Fen Dong, Jianwei Zhang, Shiming Yang · 2017 · Cancer Letters
- Role of Cripto-1 in Stem Cell Maintenance and Malignant ProgressionCaterina Bianco, María Cristina Rangel, Nadia Pereira de Castro, Tadahiro Nagaoka, Kelly Rollman, Monica Gonzales, David S. Salomon · 2010 · American Journal Of Pathology
- The role of hypoxia-inducible factor-2 in digestive system cancersZhao, J, Du, F, Shen, G, Zheng, F, Xu, B · 2015 · Cell Death & Disease
- Revisiting the seed and soil in cancer metastasisMartín Mendoza, Chand Khanna · 2009 · The International Journal of Biochemistry & Cell Biology
- Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 ReceptorAkiko Murakami, Fumiyuki Takahashi, Fariz Nurwidya, Isao Kobayashi, Kunihiko Minakata, Muneaki Hashimoto, Takeshi Nara, Motoyasu Kato, Ken Tajima, Naoko Shimada et al. · 2014 · PLoS ONE
- Endoplasmic Reticulum stress-dependent expression of ERO1L promotes aerobic glycolysis in Pancreatic CancerJunfeng Zhang, Jian‐Yu Yang, Chaoyi Lin, Wei Liu, Yan‐Miao Huo, Minwei Yang, Shu‐Heng Jiang, Yongwei Sun, Rong Hua · 2020 · Theranostics
- Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem CellsSuzanne D. Westfall, Shrikesh Sachdev, Padmalaya Das, Leonard B. Hearne, Mark Hannink, R. Michael Roberts, Toshihiko Ezashi · 2008 · Stem Cells and Development
- Hypoxia Enhances Stemness of Cancer Stem Cells in Glioblastoma: An In Vitro StudyPengcheng Li, Chun Hui Zhou, Lunshan Xu, Hualiang Xiao · 2013 · International Journal of Medical Sciences
- A miR-210-3p regulon that controls the Warburg effect by modulating HIF-1α and p53 activity in triple-negative breast cancerYe Du, Na Wei, Ruolin Ma, Shu‐Heng Jiang, Dong Song · 2020 · Cell Death and Disease
- Epigenetic crosstalk between hypoxia and tumor driven by HIF regulationTiansheng Li, Chao Mao, Xiang Wang, Ying Shi, Yongguang Tao · 2020 · Journal of Experimental & Clinical Cancer Research
- Reprogramming the epigenome with vitamin CLee Chong, Taylor, Ahearn, Emily L., Cimmino, Luisa · 2019 · Frontiers in Cell and Developmental Biology
- The Tumor Microenvironment: Characterization, Redox Considerations, and Novel Approaches for Reactive Oxygen Species-Targeted Gene TherapyPolicastro, Lucia Laura, Ibañez, Irene Laura, Notcovich, Cintia, Duran, Hebe Alicia, Podhajcer, Osvaldo Luis · 2013 · Antioxidants & Redox Signaling
- Prolyl 4‐hydroxylases, master regulators of the hypoxia responseJohanna Myllyharju · 2013 · Acta Physiologica
- Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumorsXia Ke, Fei Fei, Yanke Chen, Li Xu, Zheng Zhang, Qichao Huang, Hongxin Zhang, Hushan Yang, Zhi‐Nan Chen, Jinliang Xing · 2012 · Carcinogenesis
- The wonders of 2‐deoxy‐ d ‐glucoseHaibin Xi, Metin Kurtoğlu, Théodore J. Lampidis · 2014 · IUBMB Life
- Hypoxia and the phenomenon of immune exclusionPietrobon, Violena, Marincola, Francesco M. · 2021 · Journal of Translational Medicine
- AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosolShuyang Chen, Chengqian Yin, Taotao Lao, Dongming Liang, Dan He, Chenguang Wang, Nianli Sang · 2015 · Cell Cycle
- Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironmentTakanori Eguchi, Chiharu Aoki Sogawa, Yuka Okusha, Kenta Uchibe, Ryosuke Iinuma, Kisho Ono, Keisuke Nakano, Jun Murakami, Manabu Itoh, Kazuya Arai et al. · 2018 · PLoS ONE
- Brain cancer propagating cells: biology, genetics and targeted therapiesCostas G. Hadjipanayis, Erwin G. Van Meir · 2009 · Trends in Molecular Medicine
- Leukemia stem cells in T-ALL require active Hif1α and Wnt signalingVincenzo Giambra, Catherine E. Jenkins, Sonya H.L. Lam, Catherine Hoofd, Miriam Belmonte, Xuehai Wang, Sam Gusscott, Deanne Gracias, Andrew P. Weng · 2015 · Blood
- VEGF Promotes Proliferation of Human Glioblastoma Multiforme Stem‐Like Cells through VEGF Receptor 2Chengshi Xu, Xing Wu, Jianhong Zhu · 2013 · The Scientific World JOURNAL
- Hypoxia-induced Bmi1 promotes renal tubular epithelial cell–mesenchymal transition and renal fibrosis via PI3K/Akt signalRui Du, Lin Xia, Xiaoxuan Ning, Limin Liu, Wenjuan Sun, Chen Huang, Hanmin Wang, Shiren Sun · 2014 · Molecular Biology of the Cell