Hypoxia-Inducible Factors, Stem Cells, and Cancer

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Takahashi, K., & Yamanaka, S. (2006) · Cell · doi:10.1016/j.cell.2006.07.024 · Cited by 26,673

Stem cells, cancer, and cancer stem cells

Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001) · Nature · doi:10.1038/35102167 · Cited by 9,738

Angiogenesis in cancer and other diseases

Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070

Targeting HIF-1 for cancer therapy

Semenza, G. L. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1187 · Cited by 6,717

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Niwa, H., Miyazaki, J., & Smith, A. G. (2000) · Nature Genetics · doi:10.1038/74199 · Cited by 3,904

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Kiel, M. J., Yilmaz, Ö. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005) · Cell · doi:10.1016/j.cell.2005.05.026 · Cited by 3,168

Notch signalling: a simple pathway becomes complex

Bray, S. J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2009 · Cited by 2,620

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

Loh, Y., Wu, Q., Chew, J.-L., Vega, V. B., Zhang, W., Chen, X., Bourque, G., George, J., Leong, B., Liu, J., et al. (2006) · Nature Genetics · doi:10.1038/ng1760 · Cited by 2,438

Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

Lee, T. I., Jenner, R. G., Boyer, L. A., Guenther, M. G., Levine, S. S., Kumar, R., Chevalier, B. S., Johnstone, S. E., Cole, M. F., Isono, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.02.043 · Cited by 2,296

Hypoxia signalling in cancer and approaches to enforce tumour regression

Pouysségur, J., Dayan, F., & Mazure, N. M. (2006) · Nature · doi:10.1038/nature04871 · Cited by 1,676

Hypoxia-induced metabolic reprogramming in mesenchymal stem cells: unlocking the regenerative potential of secreted factors

Jaraba-Álvarez, W. V., Uscanga‐Palomeque, A. C., Sanchez-Giraldo, V., Madrid, C., Ortega-Arellano, H., Halpert-Correa, K., & Quintero-Gil, C. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1609082 · Cited by 19

Accumulation and penetration behavior of hypericin in glioma tumor spheroids studied by fluorescence microscopy and confocal fluorescence lifetime imaging microscopy

Bassler, M. C., Rammler, T., Wackenhut, F., Oven‐Krockhaus, S. Z., Secic, I., Ritz, R., Meixner, A. J., & Brecht, M. (2022) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-022-04107-2 · Cited by 18

Self-Sustained Regulation or Self-Perpetuating Dysregulation: ROS-dependent HIF-YAP-Notch Signaling as a Double-Edged Sword on Stem Cell Physiology and Tumorigenesis

Guo, C. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.862791 · Cited by 19

Reshaping immunometabolism in the tumour microenvironment to improve cancer immunotherapy

Chen, S., Duan, H., & Sun, G. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114963 · Cited by 18

Self-assembled carrier-free nanomedicine suppresses tumor stemness to overcome the acquired drug-resistance of hepatocellular carcinoma

Lin, H., Xu, Q., Zhang, F., Wu, H., Hu, B., Chen, G., Ban, X., Duan, X., & Yu, M. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.145555 · Cited by 18

The Zebrafish Equivalent of Alzheimer’s Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress

Ebrahimie, E., Nik, S. H. M., Newman, M., der Hoek, M. B. V., & Lardelli, M. T. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150678 · Cited by 19

Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells

Schibler, J., Tomanek‐Chalkley, A., Reedy, J. L., Zhan, F., Spitz, D. R., Schultz, M. K., & Goel, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167323 · Cited by 17

Metabolic Alterations at the Crossroad of Aging and Oncogenesis

Raffaghello, L., & Longo, V. D. (2017) · International review of cytology · doi:10.1016/bs.ircmb.2017.01.003 · Cited by 19

Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis

Chang, W. H., & Lai, A. G. (2019) · Translational research · doi:10.1016/j.trsl.2019.02.008 · Cited by 17

High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma

Lin, C., Li, H., Liu, Y., Kuo, P.-F., Wang, W., Lin, F., Chang, W.-L., Sheu, B., Wang, Y., Hung, W.-C., et al. (2019) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758835919875324 · Cited by 18

Role of Polycomb-group genes in sustaining activities of normal and malignant stem cells

Takihara, Y. (2007) · International Journal of Hematology · doi:10.1007/s12185-007-0006-y · Cited by 18

In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors

Pore, N., Jalla, S., Liu, Z., Higgs, B. W., Sorio, C., Scarpa, A., Hollingsworth, R. E., Tice, D. A., & Michelotti, E. F. (2015) · Neoplasia · doi:10.1016/j.neo.2015.05.001 · Cited by 18

Baf155 regulates skeletal muscle metabolism via HIF-1a signaling

Kang, J., Kim, D., Rhee, J., Seo, J., Park, I., Kim, J.-H., Lee, D. S., Lee, W., Kim, Y. L., Yoo, K., et al. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3002192 · Cited by 19

HIF-1α/MMP-9 Axis Is Required in the Early Phases of Skeletal Myoblast Differentiation under Normoxia Condition In Vitro

Chellini, F., Tani, A., Parigi, M., Palmieri, F., Garella, R., Zecchi‐Orlandini, S., Squecco, R., & Sassoli, C. (2023) · Cells · doi:10.3390/cells12242851 · Cited by 18

Glioblastoma cancer stem cells: Basis for a functional hypothesis

Schiffer, D., Mellai, M., Annovazzi, L., Piazzi, A., Monzeglio, O., & Caldera, V. (2012) · Stem Cell Discovery · doi:10.4236/scd.2012.23017 · Cited by 17

Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer

Lu, C.-S., Hsieh, J.-L., Lin, C.-Y., Tsai, H.-W., Su, B.-H., Shieh, G.-S., Su, Y.-C., Lee, C.-H., Chang, M.-Y., Wu, C., et al. (2015) · Gene Therapy · doi:10.1038/gt.2014.122 · Cited by 17

Oral Cancer Stem Cells Microenvironment

Naik, P. P., Panda, P. K., & Bhutia, S. K. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-69194-7_11 · Cited by 17

Pluripotency Transcription Factors and Metabolic Reprogramming of Mitochondria in Tumor-Initiating Stem-like Cells

Machida, K. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7241 · Cited by 18

New insights into Vitamin C function: Vitamin C induces JAK2 activation through its receptor-like transporter SVCT2

Han, Z., Zhang, Z., Guan, Y., Chen, B., Yu, M., Zhang, L., Fang, J., Gao, Y., & Guo, Z. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.01.120 · Cited by 18

CircCDR1as Suppresses Bone Microvascular Endothelial Cell Activity and Angiogenesis Through Targeting miR ‐135b/ FIH ‐1 Axis

Mao, Z., Liu, G., Xiao, G., Zhao, C., & Zou, Y. (2021) · Orthopaedic Surgery · doi:10.1111/os.12883 · Cited by 17

Hypoxia-Mediated Regulation of Stem Cell Fate

Singh, R. P., Franke, K., & Wielockx, B. (2012) · High Altitude Medicine & Biology · doi:10.1089/ham.2012.1043 · Cited by 19

Hypoxic and Reoxygenated Microenvironment: Stemness and Differentiation State in Glioblastoma

Gaelzer, M. M., dos Santos, M. S., Coelho, B. P., de Quadros, A. H., Simão, F., Usach, V., Guma, F. T. C. R., Setton-Avruj, C. P., Lenz, G., & Salbego, C. G. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0126-6 · Cited by 17

Effect of T wist and B mi1 on intraductal papillary mucinous neoplasm of the pancreas

Ishikawa, D., Shimada, M., Utsunomiya, T., Morine, Y., Imura, S., Ikemoto, T., Arakawa, Y., Kanamoto, M., Iwahashi, S., Saito, Y., et al. (2014) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12652 · Cited by 17

Intestinal HIF-2α Regulates GLP-1 Secretion via Lipid Sensing in L-Cells

Mooli, R. G. R., Mukhi, D., Pasupulati, A. K., Evers, S. S., SIPULA, I. J., Jurczak, M. J., Seeley, R. J., Shah, Y. M., & Ramakrishnan, S. K. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2021.12.004 · Cited by 16

Hypoxia-Responsive Polymeric Nanoprodrugs for Combo Photodynamic and Chemotherapy

Zhao, D., Zhang, Y., Yan, Z., Ding, Y., & Liang, F. (2023) · ACS Omega · doi:10.1021/acsomega.3c08504 · Cited by 16

Genetically engineered nanomodulators elicit potent immunity against cancer stem cells by checkpoint blockade and hypoxia relief

Pan, Y., Yu, L., Liu, L., Zhang, J., Liang, S., Parshad, B., Lai, J., Ma, L., Wang, Z., & Rao, L. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.04.008 · Cited by 16

A Prominin-1-Rich Pediatric Glioblastoma: Biologic Behavior Is Determined by Oxygen Tension-Modulated CD133 Expression but Not Accompanied by Underlying Molecular Profiles

Donovan, L., Potter, N. E., Warr, T. J., & Pilkington, G. J. (2012) · Translational Oncology · doi:10.1593/tlo.11337 · Cited by 16

Normoxic Expression of Hypoxia‐Inducible Factor 1 in Rat Leydig Cells In Vivo and In Vitro

Palladino, M. A., Pirlamarla, P. R., McNamara, J., Sottas, C. M., Korah, N., Hardy, M. P., Hales, D. B., & Hermo, L. (2011) · Journal of Andrology · doi:10.2164/jandrol.110.011494 · Cited by 16

VHL Deletion Impairs Mammary Alveologenesis but Is Not Sufficient for Mammary Tumorigenesis

Seagroves, T. N., Peacock, D. L., Liao, D., Schwab, L. P., Krueger, R. L., Handorf, C. R., Haase, V. H., & Johnson, R. S. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090310 · Cited by 15

Multimodality Approaches to Treat Hypoxic Non-Small Cell Lung Cancer (NSCLC) Microenvironment

Liang, S., Galluzzo, P., Sobol, A., Skucha, S., Rambo, B., & Bocchetta, M. (2012) · Genes & Cancer · doi:10.1177/1947601912457025 · Cited by 16

Effects of resveratrol and methoxyamine on the radiosensitivity of iododeoxyuridine in U87MG glioblastoma cell line

Khoei, S., Shoja, M., Mostaar, A., & Faeghi, F. (2016) · Experimental Biology and Medicine · doi:10.1177/1535370215622583 · Cited by 16

Musashi mediates translational repression of theDrosophilahypoxia inducible factor

Bertolin, A. P., Katz, M. J., Yano, M., Pozzi, B., Acevedo, J. M., Blanco-Obregon, D., Gándara, L., Sorianello, E. M., Kanda, H., Okano, H., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw372 · Cited by 16

Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line

Daly, C. S., Flemban, A. F., Shafei, M. A., Conway, M. E., Qualtrough, D., & Dean, S. (2017) · Oncology Reports · doi:10.3892/or.2017.6125 · Cited by 17

Chemical Activation of the Hypoxia-Inducible Factor Reversibly Reduces Tendon Stem Cell Proliferation, Inhibits Their Differentiation, and Maintains Cell Undifferentiation

Menon, A., Creo, P., Piccoli, M., Bergante, S., Conforti, E., Banfi, G., Randelli, P. S., & Anastasia, L. (2018) · Stem Cells International · doi:10.1155/2018/9468085 · Cited by 15

OCT4B mediates hypoxia-induced cancer dissemination

Lin, S.-C., Chung, C.-H., Chung, C.-H., Kuo, M.-H., Hsieh, C.-H., Chiu, Y.-F., Shieh, Y., Chou, Y., & Wu, C.-W. (2018) · Oncogene · doi:10.1038/s41388-018-0487-6 · Cited by 15

Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity

Coelho, D. R., Palma, F. R., Paviani, V., He, C., Danes, J. M., Huang, Y., Calado, J. C. P., Hart, P. C., Furdui, C. M., Poole, L. B., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2110348119 · Cited by 17

Intrinsic radiation resistance of mesenchymal cancer stem cells and implications for treatment response in a murine sarcoma model.

D’Andrea, F. P. (2012) · PubMed · Cited by 16

Fibroblast growth factor and endothelin-1 receptors mediate the response of human striatal precursor cells to hypoxia

Ambrosini, S., Sarchielli, E., Comeglio, P., Porfirio, B., Gallina, P., Morelli, A., & Vannelli, G. B. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2014.12.073 · Cited by 16

CD133 expression in renal cell carcinoma (RCC) is correlated with nuclear hypoxia-inducing factor 1α (HIF-1α)

Sun, C., Song, H., Zhang, H., Hou, C., Zhai, T., Huang, L., & Zhang, L. (2012) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-012-1237-8 · Cited by 16

Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell–cell contacts

Mattauch, S., Sachs, M., & Behrens, J. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.06.022 · Cited by 17

Human Adipose-Derived Stromal/Stem Cells Induce Functional CD4 + CD25 + FoxP3 + CD127 − Regulatory T Cells Under Low Oxygen Culture Conditions

Frazier, T. P., McLachlan, J. B., Gimble, J. M., Tucker, H. A., & Rowan, B. G. (2014) · Stem Cells and Development · doi:10.1089/scd.2013.0152 · Cited by 16

Colorectal Cancer Stem Cells

Yeung, T. M., & Mortensen, N. J. M. (2009) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e3181a8738c · Cited by 16

The expanding universe of hypoxia

Zhang, H., & Semenza, G. L. (2008) · Journal of Molecular Medicine · doi:10.1007/s00109-008-0364-9 · Cited by 17

Cancer Stem Cells - Therapeutic Boon!

Shrihari, T. G. (2011) · Journal of Cancer Science & Therapy · doi:10.4172/1948-5956.1000088 · Cited by 16

Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma

Kambayashi, S., Igase, M., Kobayashi, K., KIMURA, A., MIYAMA, T. S., Baba, K., Noguchi, S., Mizuno, T., & Okuda, M. (2015) · Journal of Veterinary Medical Science · doi:10.1292/jvms.15-0258 · Cited by 15

SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer

Liu, X., Cui, Y., Gong, J., Yu, X., Cui, Y., & Xuan, Y. (2025) · Oncogene · doi:10.1038/s41388-025-03426-9 · Cited by 15

Prostate cancer stem cell dynamics in the evolution of drug resistance

Zhang, X., Zhang, X., Deng, X., Cao, J., Bao, Q., Wang, H., Chen, D., & Tang, H. (2025) · International Journal of Surgery · doi:10.1097/js9.0000000000002611 · Cited by 15

Probiotics in Counteracting the Role of Neutrophils in Cancer Metastasis

Mangrolia, U., & Osborne, J. W. (2021) · Vaccines · doi:10.3390/vaccines9111306 · Cited by 15

Hypoxic Upregulation of IER2 Increases Paracrine GMFG Signaling of Endoplasmic Reticulum Stress‐CAF to Promote Chordoma Progression via Targeting ITGB1

Zhang, T., Zheng, B., Xia, C., Wu, P., Zheng, B., Jiang, L., Li, J., Lv, G., Zhou, H., Huang, W., et al. (2024) · Advanced Science · doi:10.1002/advs.202405421 · Cited by 15

Isolation and Applications of Prostate Side Population Cells Based on Dye Cycle Violet Efflux

Gangavarapu, K. J., & Huss, W. J. (2011) · Current Protocols in Toxicology · doi:10.1002/0471140856.tx2202s47 · Cited by 15

lncTCF7 is a negative prognostic factor, and knockdown of lncTCF7 inhibits migration, proliferation and tumorigenicity in glioma

Gao, X. C., Guo, X., Xue, H., Qiu, W., Guo, X., Zhang, J., Qian, M., Li, T., Liu, Q., Shen, J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-17340-y · Cited by 15

The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling

Faria, M., Karami, S., Granados-Principal, S. M., Dey, P., Verma, A., Choi, D. S., Elemento, O., Bawa‐Khalfe, T., Chang, J. C., Ström, A., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.24134 · Cited by 15

C-MYC, HIF-1α, ERG, TKT, and GSTP1: an Axis in Prostate Cancer?

Boldrini, L., Bartoletti, R., Giordano, M., Manassero, F., Selli, C., Panichi, M., Galli, L., Farci, F., & Faviana, P. (2018) · Pathology & Oncology Research · doi:10.1007/s12253-018-0479-4 · Cited by 15

PFT1-controlled ROS balance is critical for multiple stages of root hair development in Arabidopsis

Kalaipandian, S., Chandrika, N. N. P., Tsai, Y.-H., & Schmidt, W. (2013) · Plant Signaling & Behavior · doi:10.4161/psb.24066 · Cited by 15

Implications of Oxygen Homeostasis for Tumor Biology and Treatment

Garvalov, B. K., & Acker, T. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-1-4899-7678-9_12 · Cited by 17

Biomimetic potential of cerium oxide nanoparticles in modulating the metabolic gene signature in GBM-derived cell lines

Sridharan, P., Vinothkumar, G., Pratheesh, P., & Babu, K. S. (2020) · Journal of Materials Science · doi:10.1007/s10853-020-04872-4 · Cited by 15

Hyaluronan Regulates Ceruloplasmin Production By Gliomas and Their Treatment-Resistant Multipotent Progenitors

Tye, S. L., Gilg, A. G., Tolliver, L. B., Wheeler, W. G., Toole, B. P., & Maria, B. L. (2008) · Journal of Child Neurology · doi:10.1177/0883073808321066 · Cited by 15

NSD1 promotes esophageal cancer tumorigenesis via HIF1α signaling

He, F., Xiao, H., Cai, Y., & Zhang, N. (2022) · Cell Biology and Toxicology · doi:10.1007/s10565-022-09786-2 · Cited by 14

Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance

Lamichhane, A., & Tavana, H. (2024) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-024-00798-y · Cited by 16

Pronounced hypoxia in the subventricular zone following traumatic brain injury and the neural stem/progenitor cell response

Baumann, G. K., Travieso, L. G., Liebl, D. J., & Theus, M. H. (2013) · Experimental Biology and Medicine · doi:10.1177/1535370213494558 · Cited by 14

Effect of tissue inhibitor of metalloprotease 1 on human pulp cells in vitro and rat pulp tissue in vivo

Okamoto, M., Takahashi, Y., Komichi, S., Ali, M., Watanabe, M., & Hayashi, M. (2019) · International Endodontic Journal · doi:10.1111/iej.13099 · Cited by 13

Mechanisms of ischaemic neural progenitor proliferation: a regulatory role of the HIF‐1α‐CBX7 pathway

Chiu, H. ‐., Lee, H., Lee, K. ‐., Zhao, Y. D., Hsu, C. Y., & Shyu, W. (2019) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12585 · Cited by 14

The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis

Nagata, A., Itoh, F., Sasho, A., Sugita, K., Suzuki, R., Hinata, H., Shimoda, Y., Suzuki, E., Maemoto, Y., Inagawa, T., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011222 · Cited by 14

Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer

Jang, G., Oh, J., Jun, E., Lee, J. L., Kwon, J. Y., Kim, J., Lee, S., Kim, S. C., Cho, S., & Lee, C. (2022) · npj Genomic Medicine · doi:10.1038/s41525-022-00333-w · Cited by 14

Induction of cap-independent BiP (hsp-3) and Bcl-2 (ced-9) translation in response to eIF4G (IFG-1) depletion inC. elegans

Morrison, J. K., Friday, A. J., Henderson, M. A., Hao, E., & Keiper, B. D. (2014) · Translation · doi:10.4161/trla.28935 · Cited by 13

A Unique 3D In Vitro Cellular Invasion Assay

Quail, D. F., Maciel, T. J., Rogers, K. A., & Postovit, L.-M. M. (2012) · SLAS DISCOVERY · doi:10.1177/1087057112449863 · Cited by 14

Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L

Song, C., Xu, Q., Jiang, K., Zhou, G., Yu, X., Wang, L., Zhu, Y., Fang, L., Yu, Z. S., Lee, J., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.5337 · Cited by 14

SINHCAF/FAM60A and SIN3A specifically repress HIF-2α expression

Biddlestone, J., Batie, M., Shmakova, A., Bandarra, D., Knatko, E. V., Dinkova‐Kostova, A. T., Munoz, I. M., Sundaramoorthy, R., Owen-Hughes, T., & Rocha, S. (2018) · Biochemical Journal · doi:10.1042/bcj20170945 · Cited by 17

CD 133: holy of grail of neuro‐oncology or promiscuous red‐herring?

Donovan, L., & Pilkington, G. (2012) · Cell Proliferation · doi:10.1111/j.1365-2184.2012.00842.x · Cited by 13

Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins

Rashed, F. B., Stoica, C., Macdonald, D., Elsaidi, H. R. H., Ricardo, C., Bhatt, B., Moore, J., Diaz‐Dussan, D., Ramamonjisoa, N., Mowery, Y. M., et al. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101905 · Cited by 14

Fracture repair by IOX2: Regulation of the hypoxia inducible factor-1α signaling pathway and BMSCs

Chen, C., Yan, S., Geng, Z., & Wang, Z. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.174864 · Cited by 13

A Role of Non-FDG Tracers in Lung Cancer?

Novruzov, E., Mori, Y., Antke, C., Dabir, M., Schmitt, D. R., Kratochwil, C., Koerber, S. A., Haberkorn, U., & Giesel, F. L. (2022) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2022.05.004 · Cited by 13

Redox Homeostasis and Beyond: The Role of Wild-Type Isocitrate Dehydrogenases for the Pathogenesis of Glioblastoma

Murnan, K., Horbinski, C., & Stegh, A. H. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0262 · Cited by 15

Redox System and Oxidative Stress-Targeted Therapeutic Approaches in Bladder Cancer

Dugbartey, G. J., Relouw, S., McFarlane, L., & Şener, A. (2024) · Antioxidants · doi:10.3390/antiox13030287 · Cited by 13

Metastatic Cancer Stem Cells: New Molecular Targets for Cancer Therapy

Leirós, G. J., & Balañá, M. E. (2011) · Current Pharmaceutical Biotechnology · doi:10.2174/138920111798377094 · Cited by 13

Departure from optimal O2 level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation

Yang, Y., Jiang, Z., Bolnick, A. D., Dai, J., Puscheck, E. E., & Rappolee, D. A. (2016) · Journal of Reproduction and Development · doi:10.1262/jrd.2016-110 · Cited by 13

Hypoxia activated long non-coding RNA HABON regulates the growth and proliferation of hepatocarcinoma cells by binding to and antagonizing HIF-1 alpha

Ma, C.-N., Wo, L., Wang, D.-F., Zhou, C.-X., Li, J.-C., Zhang, X., Gong, X.-F., Wang, C.-L., He, M., & Zhao, Q. (2021) · RNA Biology · doi:10.1080/15476286.2020.1871215 · Cited by 13

Glycogen synthase kinase GSK3α promotes tumorigenesis by activating HIF1/VEGFA signaling pathway in NSCLC tumor

Cao, X., Wu, W., Wang, D. W., Sun, W., & Lai, S. (2022) · Cell Communication and Signaling · doi:10.1186/s12964-022-00825-3 · Cited by 13

Road testing new CAR design strategies in multiple myeloma

Rana, P. S., Murphy, E. V., Kort, J., & Driscoll, J. J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.957157 · Cited by 14

IGFL2‐AS1 ‐induced suppression of HIF ‐1α degradation promotes cell proliferation and invasion in colorectal cancer by upregulating CA9

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