Hypoxia-Inducible Factors, Stem Cells, and Cancer

Keith, Brian, Simon, M. Celeste·2007·Cell

Cited by (1,000)

Items 601–700 of 1,000

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  3. Hypoxia and the Receptor for Advanced Glycation End Products (RAGE) Signaling in Cancer
    Sakshi Taneja, Stefan W. Vetter, Estelle Leclerc · 2021 · International Journal of Molecular Sciences
  4. Hypoxia-Mimetic CoCl2 Agent Enhances Pro-Angiogenic Activities in Ovine Amniotic Epithelial Cells-Derived Conditioned Medium
    Miriam Di Mattia, Annunziata Mauro, Simona Delle Monache, Fanny Pulcini, Valentina Russo, Paolo Berardinelli, Maria Rita Citeroni, Maura Turriani, Alessia Peserico, Barbara Barboni · 2022 · Cells
  5. Aberrant expression and functions of protocadherins in human malignant tumors
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  6. Regulation of antioxidant systems in response to anoxia and reoxygenation in Rana sylvatica
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  7. Synergy between Photodynamic Therapy and Dactinomycin Chemotherapy in 2D and 3D Ovarian Cancer Cell Cultures
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  8. Regulation of intestinal cancer stem cells
    Neil Ashley · 2012 · Cancer Letters
  9. Role of TXNDC5 in tumorigenesis of colorectal cancer cells: In vivo and in vitro evidence
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  11. Application of hypoxia-mesenchymal stem cells in treatment of anaerobic bacterial wound infection: wound healing and infection recovery
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  12. Hypoxia induces osteogenic/angiogenic responses of bone marrow‐derived mesenchymal stromal cells seeded on bone‐derived scaffolds via ERK1/2 and p38 pathways
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  13. Differential expression of HIF-1α in CD44+CD24-/low breast ductal carcinomas
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    Michael R. Blatchley, Kyung Min Park, Sharon Gerecht · 2015 · Journal of Materials Chemistry B
  15. Cell-Cycle Regulation in Embryonic Stem Cells: Centrosomal Decisions on Self-Renewal
    Zuzana Sumbalova Koledova, Alwin Krämer, Leona Raskova Kafkova, Vladimír Divoký · 2010 · Stem Cells and Development
  16. A nano-based thermotherapy for cancer stem cell-targeted therapy
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  17. From viruses to cancer stem cells: Dissecting the pathways to malignancy
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  18. Redox regulation of stem cell mobilizationThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.
    István Lekli, Narasimman Gurusamy, Diptarka Ray, Árpád Tósaki, Dipak Kumar Das · 2009 · Canadian Journal of Physiology and Pharmacology
  19. Downregulation of AIF by HIF-1 contributes to hypoxia-induced epithelial–mesenchymal transition of colon cancer
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  20. Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
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  21. Sonic hedgehog signaling regulates hypoxia/reoxygenation‑induced H9C2 myocardial cell apoptosis
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  27. The Roles of Hypoxia-Inducible Factors in Regulating Neural Stem Cells Migration to Glioma Stem Cells and Determinating Their Fates
    Suojun Zhang, Xiao Luo, Feng Wan, Ting Lei · 2012 · Neurochemical Research
  28. Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy
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  29. Stem cell factor is a novel independent prognostic biomarker for hepatocellular carcinoma after curative resection
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  30. The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions
    Yoo Jin Choi, Kyu Heo, Hee Sung Park, Kwangmo Yang, Min Ho Jeong · 2016 · International Journal of Oncology
  31. Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories
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  32. Comprehensive proteogenomic analysis of human embryonic and induced pluripotent stem cells
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  33. GATA6 enhances the stemness of human colon cancer cells by creating a metabolic symbiosis through upregulating LRH‐1 expression
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  34. Hypoxia upregulates aldehyde dehydrogenase isoform 1 (ALDH1) expression and induces functional stem cell characteristics in human glioblastoma cells
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  35. ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation
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  37. Quantifying Reoxygenation in Pancreatic Cancer During Stereotactic Body Radiotherapy
    Edward Taylor, Jitao Zhou, Patricia E Lindsay, Warren D. Foltz, May Cheung, Iram Fatima S. Siddiqui, Ali Hosni, Ahmed El Amir, John Kim, Richard Peter Hill et al. · 2020 · Scientific Reports
  38. Hypoxia-induced EPHB2 promotes invasive potential of glioblastoma.
    Wenjin Qiu, Shibin Song, Wei Chen, Jiale Zhang, Hua Yang, Yimin Chen · 2019 · Europe PMC (PubMed Central)
  39. Glioma stem cells: turpis omen in nomen? (the evil in the name?)
    E. Binda, B. Reynolds, Angelo L. Vescovi · 2014 · Journal of Internal Medicine
  40. miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway
    Zhongquan Zhou, Songwen Chen, Zhiming Tian, Shibing Deng, YI Xu-ying, Shaning Yang, Yang Xuexin, Lijun Jin, Wanqing Shi · 2020 · Acta Biochimica et Biophysica Sinica
  41. Prostate Cancer Stem Cells: Biology and Treatment Implications
    Ioannis M. Koukourakis, Kalliopi Platoni, Vassilis Kouloulias, Stella Arelaki, Anna G. Zygogianni · 2023 · International Journal of Molecular Sciences
  42. Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits
    Maura Calvani, Francesca Bianchini, Maria Letizia Taddei, Matteo Becatti, Elisa Giannoni, Paola Chiarugi, Lido Calorini · 2016 · Oncotarget
  43. Cancer stem cells in breast and prostate: Fact or fiction?
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  44. The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism
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  45. Lactate metabolism reprogramming in PDAC: Potential for tumor therapy
    Fan Gao, Kang Sun, Sicheng Wang, Xiaozhen Zhang, Xueli Bai · 2025 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  46. Suppression of Glioma Progression by Egln3
    Vicki A. Sciorra, Michael A. Sanchez, Akemi Kunibe, Andrew E. Wurmser · 2012 · PLoS ONE
  47. Biomaterials to suppress cancer stem cells and disrupt their tumoral niche.
    Carla Garcia-Mazas, N. Csaba, Marcos Garcia-Fuentes · 2017 · International journal of pharmaceutics
  48. The role of macrophage in regulating tumour microenvironment and the strategies for reprogramming tumour-associated macrophages in antitumour therapy
    Liping Xu, Xiaoli Xie, Ying Luo · 2021 · European Journal of Cell Biology
  49. Cell‐Membrane‐Derived Nanoparticles with Notch‐1 Suppressor Delivery Promote Hypoxic Cell–Cell Packing and Inhibit Angiogenesis Acting as a Two‐Edged Sword
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  50. Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice
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  51. A gene for all seasons: The evolutionary consequences of HIF-1 in carcinogenesis, tumor growth and metastasis
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  52. Imaging and Therapy of Pancreatic Cancer with Phosphatidylserine-Targeted Nanovesicles
    Victor Blanco, Tahir Latif, Zhengtao Chu, Xiaoyang Qi · 2015 · Translational Oncology
  53. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress
    Po‐Jen Chen, Jui-Yun Weng, Pang‐Hung Hsu, Jin‐Yuh Shew, Yi‐Shuian Huang, Wen‐Hwa Lee · 2015 · Nucleic Acids Research
  54. The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment
    Yuuri Hashimoto, Hiroshi Tazawa, Fuminori Teraishi, Toru Kojima, Yuichi Watanabe, Futoshi Uno, Shuya Yano, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara · 2012 · PLoS ONE
  55. A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells
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  56. Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer
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  57. Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies
    Yudong Wang, Filip Jankú, Sarina Anne Piha-Paul, Kenneth R. Hess, Russell R. Broaddus, Lidong Liu, Naiyi Shi, Michael James Overman, Scott Kopetz, Vivek Subbiah et al. · 2020 · Scientific Reports
  58. Radiotherapy-Resistant Breast Cancer Cells Enhance Tumor Progression by Enhancing Premetastatic Niche Formation through the HIF-1α-LOX Axis
    Gyung Hyuck Ko, Trojan Rugira, Hana Jin, Young Nak Joo, Hye Jung Kim · 2020 · International Journal of Molecular Sciences
  59. Effects of hypoxia on proliferation of human cord blood-derived mesenchymal stem cells
    Longying Peng, Xiaomei Shu, Changhui Lang, Xiaohua Yu · 2015 · Cytotechnology
  60. A Novel Polyamine-Targeted Therapy for BRAF Mutant Melanoma Tumors
    Molly C. Peters, Allyson R. Minton, Otto Phanstiel, Susan K. Gilmour · 2018 · Medical Sciences
  61. HKDC1 promotes liver cancer stemness under hypoxia through stabilizing β-catenin
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  62. Combinatorial Control of Transgene Expression by Hypoxia-Responsive Promoter and MicroRNA Regulation for Neural Stem Cell-Based Cancer Therapy
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  63. Multi-cellular aggregates, a model for living matter
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  64. Stimuli-responsive polyprodrug for cancer therapy
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  68. Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells
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  69. Radioresistance and Cancer Stem Cells: Survival of the Fittest
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  70. Active Role of the Necrotic Zone in Desensitization of Hypoxic Macrophages and Regulation of CSC-Fate: A hypothesis
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  71. Tenascin-C is involved in promotion of cancer stemness via the Akt/HIF1ɑ axis in esophageal squamous cell carcinoma
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  72. Functional Interaction of Hypoxia-Inducible Factor 2-Alpha and Autophagy Mediates Drug Resistance in Colon Cancer Cells
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  74. Anticancer therapeutics: A surge of new developments increasingly target tumor and stroma
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  75. The hypoxic microenvironment: A determinant of cancer stem cell evolution
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  76. NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC
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  92. Cancer stem cell and niche
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  93. Enhancing radiotherapy techniques for Triple-Negative breast cancer treatment
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  97. Over expression of HIF-1α in human mesenchymal stem cells increases their supportive functions for hematopoietic stem cells in an experimental co-culture model
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  98. Synergistic role of three dimensional niche and hypoxia on conservation of cancer stem cell phenotype
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  100. Defining the Plant Germ Line—Nature or Nurture?
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