Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie E., Habib, Naomi, Yosef, Nir +17 more·2011·Cell

Cited by (949)

Items 101–200 of 949

  1. The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe?
    Stephin J. Vervoort, Ruben van Boxtel, Paul James Coffer · 2012 · Oncogene
  2. Nutrigenomics of Vitamin D
    Carsten Carlberg · 2019 · Nutrients
  3. Identification of transcriptional regulators in the mouse immune system
    Vladimir Jojic, Tal Shay, Katelyn Sylvia, Or Zuk, Xin Sun, Joonsoo Kang, Aviv Regev, Daphne Koller · 2013 · Nature Immunology
  4. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease
    Olivia M. de Goede, Daniel C. Nachun, Nicole M. Ferraro, Michael J. Gloudemans, Abhiram S. Rao, Craig Smail, Tiffany Y. Eulalio, François Aguet, Bernard Ng, Jishu Xu et al. · 2021 · Cell
  5. Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
    Kuusanmäki, Heikki, Leppä, Aino-Maija, Pölönen, Petri, Kontro, Mika, Dufva, Olli, Deb, Debashish, Yadav, Bhagwan, Brück, Oscar, Kumar, Ashwini, Everaus, Hele et al. · 2020 · Haematologica
  6. The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny
    Shannon McKinney‐Freeman, Patrick Cahan, Hu Li, Scott Allen Lacadie, Hsuan-Ting Huang, Matthew S. Curran, Sabine Loewer, Olaia Naveiras, Katie L. Kathrein, Martina Konantz et al. · 2012 · Cell stem cell
  7. Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer
    Michela Masetti, Roberta Carriero, Federica Portale, Giulia Marelli, Nicolò Morina, Marta Pandini, Marta Iovino, Bianca Partini, Marco Erreni, Andrea Ponzetta et al. · 2021 · The Journal of Experimental Medicine
  8. Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
    Mann, Mati, Mehta, Arnav, de Boer, Carl G., Kowalczyk, Monika S., Lee, Kevin, Haldeman, Pearce, Rogel, Noga, Knecht, Abigail R., Farouq, Daneyal, Regev, Aviv et al. · 2018 · Cell Reports
  9. Epigenetics of haematopoietic cell development
    Howard Cedar, Yehudit Bergman · 2011 · Nature reviews. Immunology
  10. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
    Ptasinska, A, Assi, S A, Mannari, D, James, S R, Williamson, D, Dunne, J, Hoogenkamp, M, Wu, M, Care, M, McNeill, H et al. · 2012 · Leukemia
  11. Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
    Nicolas Jacquelot, Cyril Seillet, Minyu Wang, Angela Pizzolla, Yang Liao, Soroor Hediyeh-zadeh, Sharon Grisaru‐Tal, Cynthia Louis, Qiutong Huang, Jaring Schreuder et al. · 2021 · Nature Immunology
  12. Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages
    Casero, David, Sandoval, Salemiz, Seet, Christopher S, Scholes, Jessica, Zhu, Yuhua, Ha, Vi Luan, Luong, Annie, Parekh, Chintan, Crooks, Gay M · 2015 · Nature Immunology
  13. Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
    Els Mansell, Valgarður Sigurðsson, Elitza M. Deltcheva, John Brown, Chela T. James, Kenichi Miharada, Shamit Soneji, Jonas T. Larsson, Tariq Enver · 2020 · Cell stem cell
  14. Comparative Analysis of Gene Regulatory Networks: From Network Reconstruction to Evolution
    Dawn Anne Thompson, Aviv Regev, Sushmita Roy · 2015 · Annual Review of Cell and Developmental Biology
  15. Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis
    Emmanouil I. Athanasiadis, Jan Gregor Botthof, Helena Andrés-Terré, Lauren Ferreira, Píetro Lió, Ana Cvejic · 2017 · Nature Communications
  16. Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms
    William Tapper, Amy V. Jones, Róbert Královics, Ashot S. Harutyunyan, Katerina Zoi, William C.Y. Leung, Anna L. Godfrey, Paola Guglielmelli, Alison Callaway, Daniel Ward et al. · 2015 · Nature Communications
  17. In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
    P. Miller, F. Al-Shahrour, Kimberly A. Hartwell, L. Chu, M. Järås, Rishi V. Puram, A. Puissant, K. Callahan, J. Ashton, Marie McConkey et al. · 2013 · Cancer Cell
  18. Quantification of cell identity from single-cell gene expression profiles
    Idan Efroni, Pui-Leng Ip, Tal Nawy, Alison J. Mello, Kenneth D. Birnbaum · 2015 · Genome biology
  19. A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells
    Li, Li, Bowling, Sarah, McGeary, Sean E., Yu, Qi, Lemke, Bianca, Alcedo, Karel, Jia, Yuemeng, Liu, Xugeng, Ferreira, Mark, Klein, Allon M. et al. · 2023 · Cell
  20. Targeting MTHFD2 in acute myeloid leukemia
    Yana Pikman, Alexandre Puissant, Gabriela Alexe, Andrew A. Furman, Liying M. Chen, Stacey M. Frumm, Linda S. Ross, Nina Fenouille, Christopher F. Bassil, Caroline A. Lewis et al. · 2016 · The Journal of Experimental Medicine
  21. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis
    Aaron D. Viny, Christopher J. Ott, Barbara G. Spitzer, Martín A. Rivas, Cem Meydan, Efthymia Papalexi, Dana Yelin, KAITLYN R. SHANK, Jaime M. Reyes, April Chiu et al. · 2015 · The Journal of Experimental Medicine
  22. Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans
    Jarny Choi, T. Baldwin, M. Wong, Jessica E. Bolden, K. Fairfax, Erin C. Lucas, Rebecca Cole, C. Biben, Clare Morgan, K. Ramsay et al. · 2018 · Nucleic Acids Res.
  23. Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis
    Michelle Flynn, Michael James Kraakman, Christos Tikellis, Man K.S. Lee, Nordin M.J. Hanssen, Hélène L. Kammoun, R. J. Pickering, Dragana Dragoljevic, Annas Al‐Sharea, Tessa J. Barrett et al. · 2020 · Circulation Research
  24. The non-coding RNA landscape of human hematopoiesis and leukemia
    Adrian Schwarzer, Stephan Emmrich, Franziska Schmidt, Dominik Beck, Michelle Shu Wen Ng, Christina Reimer, Felix F. Adams, Sarah Grasedieck, Damian Witte, Sebastian Käbler et al. · 2017 · Nature Communications
  25. CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia
    Megan E. McNerney, Christopher D. Brown, Xiaoyue Wang, Elizabeth T. Bartom, Subhradip Karmakar, Chaitanya Bandlamudi, Shan Yu, Jinkyung Ko, Barry P. Sandall, Thomas P. Stricker et al. · 2012 · Blood
  26. Vitamin D and Its Target Genes
    Carsten Carlberg · 2022 · Nutrients
  27. Immunological Genome Project and systems immunology
    Tal Shay, Joonsoo Kang · 2013 · Trends in Immunology
  28. Genetically distinct leukemic stem cells in human CD34− acute myeloid leukemia are arrested at a hemopoietic precursor-like stage
    Lynn Swun Quek, Georg Otto, Catherine Garnett, Ludovic Lhermitte, Dimitris Karamitros, Bilyana Stoilova, I‐Jun Lau, Jessica B. Doondeea, Batchimeg Usukhbayar, Alison Kennedy et al. · 2016 · The Journal of Experimental Medicine
  29. Haematopoietic stem cells: past, present and future
    Ashley P. Ng, Warren S. Alexander · 2017 · Cell Death Discovery
  30. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells
    Jeremy D. Grevet, Xianjiang Lan, Nicole Hamagami, Christopher R. Edwards, Laavanya Sankaranarayanan, Xinjun Ji, Saurabh K. Bhardwaj, Carolyne J. Face, David F. Posocco, Osheiza Y. Abdulmalik et al. · 2018 · Science
  31. Large-Scale Quality Analysis of Published ChIP-seq Data
    Georgi K. Marinov, Anshul Bharat Kundaje, Peter J. Park, Barbara J. Wold · 2013 · G3 Genes Genomes Genetics
  32. Making Sense of Transcription Networks
    Trevor R. Sorrells, Alexander D. Johnson · 2015 · Cell
  33. CircRNAs in hematopoiesis and hematological malignancies
    Annagiulia Bonizzato, Enrico Gaffo, Geertruy te Kronnie, Stefania Bortoluzzi · 2016 · Blood Cancer Journal
  34. Unifying immunology with informatics and multiscale biology
    Brian A. Kidd, Lauren A Peters, Eric E. Schadt, Joel T. Dudley · 2014 · Nature Immunology
  35. Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage
    Carolien M. Woolthuis, Christopher Y. Park · 2016 · Blood
  36. Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans
    Nicholas Giovannone, J. Liang, Aristotelis Antonopoulos, Jenna Geddes-Sweeney, Sandra L. King, Stephen M. Pochebit, Neil Bhattacharyya, G. S. Lee, Anne Dell, Hans R. Widlund et al. · 2018 · Nature Communications
  37. Biomimetic Platforms for Human Stem Cell Research
    Gordana Vunjak‐Novakovic, David T. Scadden · 2011 · Cell stem cell
  38. A general method to derive robust organ-specific gene expression-based differentiation indices: application to thyroid cancer diagnostic
    G. Tomás, Maxime Tarabichi, David Gacquer, Aline Hébrant, Geert Dom, J.E. Dumont, Xavier M. Keutgen, Thomas J. Fahey, Carine Maenhaut, Vincent Detours · 2012 · Oncogene
  39. G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment
    Xiaoji Chen, Kyobi Skutt-Kakaria, Jerry Davison, Yang-Li Ou, Edward Choi, Punam Malik, Keith R. Loeb, Brent Lee Wood, George E. Georges, Beverly Torok‐Storb et al. · 2012 · Genes & Development
  40. Contractile Forces Sustain and Polarize Hematopoiesis from Stem and Progenitor Cells
    Jae‐Won Shin, Amnon Buxboim, Kyle R. Spinler, Joe Swift, David A. Christian, Christopher A. Hunter, Catherine Léon, Christian Gachet, P.C. Dave P. Dingal, Irena Lambrova Ivanovska et al. · 2013 · Cell stem cell
  41. Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes
    Beck, Dominik, Thoms, Julie A. I., Perera, Dilmi, Schütte, Judith, Unnikrishnan, Ashwin, Knezevic, Kathy, Kinston, Sarah J., Wilson, Nicola K., O’Brien, Tracey A., Göttgens, Berthold et al. · 2013 · Blood
  42. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation
    Brenden W. Smith, Sarah S. Rozelle, Amy Leung, Jessalyn M. Ubellacker, Ashley J. Parks, Shirley Nah, Deborah L. French, Paul J. Gadue, Stefano Monti, David H.K. Chui et al. · 2013 · Blood
  43. The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia
    Marc R. Mansour, Takaomi Sanda, Lee N. Lawton, Xiaoyu Li, Taras Kreslavsky, Carl D. Novina, Marjorie Brand, Alejandro Gutiérrez, Michelle A. Kelliher, Catriona H. M. Jamieson et al. · 2013 · The Journal of Experimental Medicine
  44. Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP
    Maoxiang Qian, Hui Zhang, Shirley Kow Yin Kham, Shuguang Liu, Chuang Jiang, Xujie Zhao, Yi Lü, Charnise Goodings, Ting-Nien Lin, Ranran Zhang et al. · 2016 · Genome Research
  45. Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies
    Caleb J. Bashor, Nikit Patel, Sandeep Choubey, Ali Beyzavi B, Jané Kondev, James J. Collins, Ahmad S. Khalil · 2019 · Science
  46. clustifyr: an R package for automated single-cell RNA sequencing cluster classification
    Fu, Rui, Gillen, Austin E., Sheridan, Ryan M., Tian, Chengzhe, Daya, Michelle, Hao, Yue, Hesselberth, Jay R., Riemondy, Kent A. · 2020 · F1000Research
  47. Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
    Stefan Rentas, Nicholas Timothy Holzapfel, Muluken S. Belew, Gabriel A. Pratt, Véronique Voisin, Brian T. Wilhelm, Gary D. Bader, Gene Wei-Ming Yeo, Kristin J. Hope · 2016 · Nature
  48. Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy
    Hussein A. Abbas, Dapeng Hao, Katarzyna J. Tomczak, Praveen Barrodia, Jin Seon Im, Patrick Kevin Reville, Zoe Alaniz, Wei Wang, Ruiping Wang, Feng Wang et al. · 2021 · Nature Communications
  49. Genetic loss of SH2B3 in acute lymphoblastic leukemia
    Arianne Pérez-García, Alberto Ambesi‐Impiombato, Michael Hadler, Isaura Rigo, Charles A. LeDuc, Kara M. Kelly, Chaim Jalas, Elisabeth M. Paietta, Janis Racevskis, Jacob M. Rowe et al. · 2013 · Blood
  50. Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging
    Jakobsen, Niels Asger, Turkalj, Sven, Zeng, Andy G.X., Stoilova, Bilyana, Metzner, Marlen, Rahmig, Susann, Nagree, Murtaza S., Shah, Sayyam, Moore, Rachel, Usukhbayar, Batchimeg et al. · 2024 · Cell Stem Cell
  51. Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation
    Isabel Ferreirós-Vidal, Thomas Carroll, Ben Taylor, Anna V. Terry, Ziwei Liang, Ludovica Bruno, Gopuraja Dharmalingam, Sanjay P. Khadayate, Bradley S. Cobb, Stephen T. Smale et al. · 2013 · Blood
  52. Single-cell transcriptome and TCR profiling reveal activated and expanded T cell populations in Parkinson’s disease
    Pingping Wang, Lifen Yao, Meng Luo, Wenyang Zhou, Xiyun Jin, Zhaochun Xu, Yan Shi, Yiqun Li, Chang Xu, Rui Cheng et al. · 2021 · Cell Discovery
  53. Human germline heterozygous gain-of-function <i>STAT6</i> variants cause severe allergic disease
    Sharma, Mehul, Leung, Daniel, Momenilandi, Mana, Jones, Lauren C.W., Pacillo, Lucia, James, Alyssa E., Murrell, Jill R., Delafontaine, Selket, Maimaris, Jesmeen, Vaseghi-Shanjani, Maryam et al. · 2023 · Journal of Experimental Medicine
  54. CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations
    Maria D. Chikina, Elena Zaslavsky, Stuart C. Sealfon · 2015 · Bioinformatics
  55. Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis
    Julia R. Kardon, Yvette Y. Yien, Nicholas C. Huston, Diana S. Branco, Gordon J. Hildick-Smith, Kyu Young Rhee, Barry H. Paw, Tania A. Baker · 2015 · Cell
  56. CD56negCD16+NK cells are activated mature NK cells with impaired effector function during HIV-1 infection
    Jeffrey M. Milush, Sandra López‐Vergès, Vanessa A. York, Steven G. Deeks, Jeffrey N. Martin, Frederick M. Hecht, Lewis L. Lanier, Douglas F. Nixon · 2013 · Retrovirology
  57. Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
    Judith Wienke, Lindy L. Visser, Waleed M. Kholosy, Kaylee M. Keller, Marta Barisa, Evon Poon, Sophie Munnings-Tomes, Courtney Himsworth, Elizabeth A. Calton, Ana Isabel Enríquez Rodríguez et al. · 2024 · Cancer Cell
  58. scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data
    Luyi Tian, Shian Su, Xueyi Dong, Daniela Amann‐Zalcenstein, Christine Biben, Azadeh Seidi, Douglas J. Hilton, Shalin H. Naik, Matthew E. Ritchie · 2018 · PLoS Computational Biology
  59. Robust isolation of malignant plasma cells in multiple myeloma
    Ildikó Frigyesi, Jörgen Adolfsson, Mina Ali, Mikael Kronborg Christophersen, Ellinor Johnsson, Ingemar Turesson, Urban Gullberg, Markus Hansson, Björn Nilsson · 2014 · Blood
  60. PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions
    Wenlian Qiao, Gerald Quon, Elizabeth Csaszar, Mei Yu, Quaid Morris, Peter W. Zandstra · 2012 · PLoS Computational Biology
  61. Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
    Xiaorong Gu, Quteba Ebrahem, Reda Z. Mahfouz, Metis Hasipek, Francis O. Enane, Tomas Radivoyevitch, Nicolas Rapin, Bartlomiej P. Przychodzen, Zhenbo Hu, Ramesh Balusu et al. · 2018 · Journal of Clinical Investigation
  62. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis
    Louis C. Doré, Timothy M. Chlon, Christopher D. Brown, Kevin P. White, John D. Crispino · 2012 · Blood
  63. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia
    Nina Fenouille, Christopher F. Bassil, Issam Ben‐Sahra, Lina Benajiba, Gabriela Alexe, Azucena Ramos, Yana Pikman, Amy Saur Conway, Michael R. Burgess, Qing Li et al. · 2017 · Nature Medicine
  64. Transcriptional and epigenetic regulation of T‐helper lineage specification
    Subhash Kumar Tripathi, Riitta Lahesmaa · 2014 · Immunological Reviews
  65. Pathway-level information extractor (PLIER) for gene expression data
    Weiguang Mao, Elena Zaslavsky, Boris Hartmann, Stuart C. Sealfon, Maria D. Chikina · 2019 · Nature Methods
  66. A Novel Type of Monocytic Leukemia Stem Cell Revealed by the Clinical Use of Venetoclax-Based Therapy
    Shanshan Pei, Ian T. Shelton, Austin E. Gillen, Brett M. Stevens, Maura Gasparetto, Yanan Wang, Lina Liu, Jun Liu, Tonya M. Brunetti, Krysta L. Engel et al. · 2023 · Cancer Discovery
  67. International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia
    Ondřej Hrušák, Válerie de Haas, Jitka Stančíková, Barbora Vakrmanová, Iveta Janotová, Ester Mejstříková, Václav Čapek, Jan Trka, Marketa Kubricanova Zaliova, Aleš Lukš et al. · 2018 · Blood
  68. Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures
    Konstantin Zaitsev, Monika Bambousková, Amanda Swain, Maxim N. Artyomov · 2019 · Nature Communications
  69. Identification of sequence variants influencing immunoglobulin levels
    Stefan Jonsson, Garðar Sveinbjörnsson, Aitzkoa Lopez de Lapuente Portilla, Bhairavi Swaminathan, Rosina Plomp, Gillian Dekkers, Ram Ajore, Mina Ali, Arthur E. H. Bentlage, Evelina Elmér et al. · 2017 · Nature Genetics
  70. A single-cell survey of cellular hierarchy in acute myeloid leukemia
    Junqing Wu, Yanyu Xiao, Jie Sun, Huiyu Sun, Haide Chen, Yuanyuan Zhu, Huarui Fu, Chengxuan Yu, E Weigao, Shujing Lai et al. · 2020 · Journal of Hematology & Oncology
  71. Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis
    Gillespie, Mark A., Palii, Carmen G., Sanchez-Taltavull, Daniel, Shannon, Paul, Longabaugh, William J.R., Downes, Damien J., Sivaraman, Karthi, Espinoza, Herbert M., Hughes, Jim R., Price, Nathan D. et al. · 2020 · Molecular Cell
  72. Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes
    Carsten Carlberg · 2019 · Frontiers in Immunology
  73. Vitamin D and the risk for cancer: A molecular analysis
    Carsten Carlberg, Eunike Velleuer · 2021 · Biochemical Pharmacology
  74. The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia
    Banerji, Versha, Frumm, Stacey M., Ross, Kenneth N., Li, Loretta S., Schinzel, Anna C., Hahn, Cynthia K., Kakoza, Rose M., Chow, Kwan T., Ross, Linda, Alexe, Gabriela et al. · 2012 · Journal of Clinical Investigation
  75. Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self
    Roshni Roy Chowdhury, Jessica D’Addabbo, Xianxi Huang, Stefan Alexander Veizades, Koki Sasagawa, David M. Louis, Paul P. Cheng, Jan Sokol, Annie Jensen, Alexandria Tso et al. · 2022 · Circulation Research
  76. Generalized and scalable trajectory inference in single-cell omics data with VIA
    Shobana V. Stassen, Gwinky G. K. Yip, Kenneth K. Y. Wong, Joshua W. K. Ho, Kevin K. Tsia · 2021 · Nature Communications
  77. Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
    M. Pimkin, A. Kossenkov, Tejaswini Mishra, Christapher S. Morrissey, Wei-Sheng Wu, Cheryl A. Keller, G. Blobel, Dongwon Lee, Michael A. Beer, R. Hardison et al. · 2014 · Genome Research
  78. xCell: Digitally portraying the tissue cellular heterogeneity landscape
    Dvir Aran, Zicheng Hu, Atul Janardhan Butte · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  79. Identification of two distinct pathways of human myelopoiesis
    Roy Drissen, Supat Thongjuea, Kim Theilgaard‐Mönch, Claus Nerlov · 2019 · Science Immunology
  80. Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
    Bauke de Boer, Janine C. M. Prick, Maurien G. M. Pruis, Peter Keane, Maria Rosaria Imperato, Jennifer Jaques, Annet Z. Brouwers-Vos, Shanna M. Hogeling, Carolien M. Woolthuis, Marije T. Nijk et al. · 2018 · Cancer Cell
  81. The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness
    Geethu Emily Thomas, Grace Egan, Laura García‐Prat, Aaron D. Botham, Véronique Voisin, Parasvi S. Patel, Fieke W. Hoff, J Chin, Boaz Nachmias, Kerstin B. Kaufmann et al. · 2022 · Nature Cell Biology
  82. DUBs, the regulation of cell identity and disease
    Johanna Heideker, Ingrid E. Wertz · 2014 · Biochemical Journal
  83. Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
    Huimin Geng, Sarah K. Brennan, Thomas A. Milne, Wei‐Yi Chen, Yushan Li, Christian Hurtz, Soo-Mi Kweon, Lynette Zickl, Seyedmehdi Shojaee, Donna S Neuberg et al. · 2012 · Cancer Discovery
  84. Studying hematopoiesis using single-cell technologies
    Fang Ye, Wentao Huang, Guoji Guo · 2017 · Journal of Hematology & Oncology
  85. Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia
    Florence F. Wagner, Lina Benajiba, Arthur J. Campbell, Michel Weïwer, Joshua R. Sacher, Jennifer P. Gale, Linda S. Ross, Alexandre Puissant, Gabriela Alexe, Amy Saur Conway et al. · 2018 · Science Translational Medicine
  86. KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs
    Fangxue Yan, Jinyang Li, Jelena Milosevic, Ricardo Petroni, Suying Liu, Zhennan Shi, Salina Yuan, Janice M. Reynaga, Yuwei Qi, Joshua Rico et al. · 2021 · Cancer Discovery
  87. Expression of ABO blood-group genes is dependent upon an erythroid cell–specific regulatory element that is deleted in persons with the Bm phenotype
    Rie Sano, Tamiko Nakajima, Keiko Takahashi, Rieko Kubo, Yoshihiko Kominato, Junichi Tsukada, Haruo Takeshita, Toshihiro Yasuda, Kazuto Ito, Takayuki Maruhashi et al. · 2012 · Blood
  88. The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression
    Arnav Mehta, Jimmy L. Zhao, Nikita Sinha, Georgi K. Marinov, Mati Mann, Monika S. Kowalczyk, Rachel P. Galimidi, Xiaomi Du, Erdem Erikçi, Aviv Regev et al. · 2015 · Immunity
  89. Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells
    Roi Gazit, Brian S. Garrison, Tata Nageswara Rao, Tal Shay, James C. Costello, Jeff Ericson, Francis Kim, James J. Collins, Aviv Regev, Amy J. Wagers et al. · 2013 · Stem Cell Reports
  90. Integrative multi-omics module network inference with lemon-tree
    Bonnet, Eric, Calzone, Laurence, Michoel, Tom · 2015 · PLoS Computational Biology
  91. Prospective isolation of human erythroid lineage-committed progenitors
    Yasuo Mori, James Y. Chen, John V. Pluvinage, Jun Seita, Irving L. Weissman · 2015 · Proceedings of the National Academy of Sciences
  92. Molecular endocrinology of vitamin D on the epigenome level
    Carsten Carlberg · 2017 · Molecular and Cellular Endocrinology
  93. Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis
    Camila Farias Amorim, Fernanda O. Novais, Ba T. Nguyen, Ana M. Misic, Lucas Pedreira Carvalho, Edgar M. Carvalho, Daniel P. Beiting, Phillip Scott · 2019 · Science Translational Medicine
  94. Haemopedia: An Expression Atlas of Murine Hematopoietic Cells
    Carolyn A. de Graaf, Jarny Choi, Tracey M. Baldwin, Jessica E. Bolden, Kirsten A. Fairfax, Aaron J. Robinson, Christine Biben, Clare Morgan, Kerry A Ramsay, Ashley P. Ng et al. · 2016 · Stem Cell Reports
  95. Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs
    Dobson, Stephanie M., García-Prat, Laura, Vanner, Robert J., Wintersinger, Jeffrey, Waanders, Esmé, Gu, Zhaohui, McLeod, Jessica, Gan, Olga I., Grandal, Ildiko, Payne-Turner, Debbie et al. · 2020 · Cancer Discovery
  96. In Vivo Mapping of Notch Pathway Activity in Normal and Stress Hematopoiesis
    Philmo Oh, Camille Lobry, Jie Gao, Anastasia N. Tikhonova, Evangelia Loizou, Jan Manent, Ben Van Handel, Sherif Ibrahim, Jeffrey M. Greve, Hanna K. A. Mikkola et al. · 2013 · Cell stem cell
  97. ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia
    Cécile Thirant, Cathy Ignacimouttou, Cécile K. Lopez, M'boyba Khadija Diop, Lou Le Mouël, Clarisse Thiollier, Aurélie Siret, Phillipe Dessen, Zakia Aid, Julie Rivière et al. · 2017 · Cancer Cell
  98. Molecular Pathophysiology of Myelodysplastic Syndromes
    Lindsley, R. Coleman, Ebert, Benjamin L. · 2013 · Annual Review of Pathology: Mechanisms of Disease
  99. MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny
    S. Horton, J. Jaques, C. Woolthuis, J. V. van Dijk, M. Mesuraca, G. Huls, G. Morrone, E. Vellenga, J. Schuringa · 2013 · Leukemia
  100. Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors
    Linda C. Zuurbier, Alejandro Gutiérrez, Charles Grenfell Mullighan, Kirsten Canté-Barrett, Olivier Gevaert, Johan de Rooi, Yunlei Li, Willem K. Smits, Jessica G. C. A. M. Buijs-Gladdines, Edwin Sonneveld et al. · 2013 · Haematologica