FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Darnell, Jennifer C., Van Driesche, Sarah J., Zhang, Chaolin, Hung, Ka Ying Sharon, Mele, Aldo, Fraser, Claire E., Stone, Elizabeth F., Chen, Cynthia +5 more·2011·Cell
DOI 10.1016/j.cell.2011.06.013

Cited by (1,007)

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  2. Fragile X Syndrome: from molecular pathology to therapy
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  3. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
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  6. Fragile X syndrome.
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  7. Dopaminergic Dysregulation in Syndromic Autism Spectrum Disorders: Insights From Genetic Mouse Models
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  8. Drug discovery for autism spectrum disorder: challenges and opportunities
    Ghosh, Anirvan, Michalon, Aubin, Lindemann, Lothar, Fontoura, Paulo, Santarelli, Luca · 2013 · Nature Reviews Drug Discovery
  9. Impaired Dendritic Expression and Plasticity of h-Channels in the fmr1 Mouse Model of Fragile X Syndrome
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  10. Sensitive time-windows for susceptibility in neurodevelopmental disorders
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  11. Measuring and estimating the effect sizes of copy number variants on general intelligence in community-based samples
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  12. Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules
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  13. RNA-binding proteins balance brain function in health and disease
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  14. Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule
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  15. Tuning Specific Translation in Cancer Metastasis and Synaptic Memory: Control at the MNK–eIF4E Axis
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  16. Aberrant RNA translation in fragile X syndrome: From FMRP mechanisms to emerging therapeutic strategies
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  17. Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back
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  18. Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs
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  19. Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders
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  20. Metabotropic glutamate receptor 5 as drug target for Fragile X syndrome
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  21. Fragile X Syndrome and Targeted Treatment Trials
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  22. Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons
    Ricardos Tabet, Enora Moutin, Jérôme A. J. Becker, Dimitri Heintz, Laëtitia Fouillen, Eric Flatter, Wojciech Krężel, Violaine Alunni, Pascale Koebel, Doulaye Dembélé et al. · 2016 · Proceedings of the National Academy of Sciences
  23. Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome
    Sophie R. Thomson, Sang S. Seo, Stephanie A. Barnes, Susana R. Louros, Melania Muscas, Owen Dando, Caoimhe Kirby, David J. A. Wyllie, Giles E. Hardingham, Peter C. Kind et al. · 2017 · Neuron
  24. The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability
    Marc P. Forrest, Matthew Hill, David H. Kavanagh, Katherine E. Tansey, Adrian J. Waite, Derek J. Blake · 2017 · Schizophrenia Bulletin
  25. Channelopathies in fragile X syndrome
    Pan‐Yue Deng, Vitaly A. Klyachko · 2021 · Nature reviews. Neuroscience
  26. Fragile X syndrome: From protein function to therapy
    Claudia Bagni, Ben A. Oostra · 2013 · American Journal of Medical Genetics Part A
  27. Regulatory discrimination of mRNAs by FMRP controls mouse adult neural stem cell differentiation
    Botao Liu, Yue Li, Emily E. Stackpole, Annie Novak, Yu Gao, Lucy Zhao, Xinyu Zhao, Joel D. Richter · 2018 · Proceedings of the National Academy of Sciences
  28. Mutant Huntingtin stalls ribosomes and represses protein synthesis in a cellular model of Huntington disease
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  29. Neuronal Autophagy and Neurodevelopmental Disorders
    Kyungmin Lee, Su-Kyung Hwang, Jin‐A Lee · 2013 · Experimental Neurobiology
  30. Novel proteomic approach (PUNCH-P) reveals cell cycle-specific fluctuations in mRNA translation
    Ranen Aviner, Tamar Geiger, Orna Elroy‐Stein · 2013 · Genes & Development
  31. Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome
    Craig A. Erickson, Logan K. Wink, Balmiki Ray, Maureen C. Early, Elizabeth Stiegelmeyer, Lauren Mathieu-Frasier, Vanessa B. Patrick, Debomoy K. Lahiri, Christopher J. McDougle · 2013 · Psychopharmacology
  32. The neurobiology of autism spectrum disorders
    Mara Parellada, María José Penzol, Laura Pina‐Camacho, Carmen Moreno, Emiliano González‐Vioque, Gil Zalsman, Celso Arango · 2013 · European Psychiatry
  33. Deregulated mTOR-mediated translation in intellectual disability.
    J. A. Troca-Marín, A. Alves-Sampaio, M. Montesinos · 2012 · Progress in neurobiology
  34. Consistency between research and clinical diagnoses of autism among boys and girls with fragile <scp>X</scp> syndrome
    Klusek, J., Martin, G. E., Losh, M. · 2014 · Journal of Intellectual Disability Research
  35. Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP
    Pritha Majumder, Jen-Fei Chu, Biswanath Chatterjee, Krishna B. S. Swamy, Che-Kun James Shen · 2016 · Acta Neuropathologica
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  39. Cardiac autonomic regulation in autism and Fragile X syndrome: A review.
    Jessica Klusek, Jane E. Roberts, Molly C. Losh · 2014 · Psychological Bulletin
  40. SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy
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  41. Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R
    Kraushar, Matthew L., Thompson, Kevin, Wijeratne, H. R. Sagara, Viljetic, Barbara, Sakers, Kristina, Marson, Justin W., Kontoyiannis, Dimitris L., Buyske, Steven, Hart, Ronald P., Rasin, Mladen-Roko · 2014 · Proceedings of the National Academy of Sciences
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  43. Cellular and synaptic network defects in autism
    Peça, João, Feng, Guoping · 2012 · Current Opinion in Neurobiology
  44. Altered structural and functional synaptic plasticity with motor skill learning in a mouse model of fragile x syndrome.
    Padmashri, Ragunathan, Reiner, Benjamin C., Suresh, Anand, Spartz, Elizabeth, Dunaevsky, Anna · 2013 · The Journal of Neuroscience
  45. Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism
    Simona D’Antoni, Michela Spatuzza, Carmela Maria Bonaccorso, Sebastiano Antonino Musumeci, Lucia Ciranna, Ferdinando Nicoletti, Kimberly M. Huber, Maria Vincenza Catania · 2014 · Neuroscience & Biobehavioral Reviews
  46. Fragile X syndrome: a preclinical review on metabotropic glutamate receptor 5 (mGluR5) antagonists and drug development
    Andreea S. Pop, Baltazar Gomez‐Mancilla, Giovanni Neri, Rob Willemsen, Fabrizio Gasparini · 2013 · Psychopharmacology
  47. A Chromatin Accessibility Atlas of the Developing Human Telencephalon
    Eirene Markenscoff-Papadimitriou, Sean Whalen, Pawel F. Przytycki, Reuben Thomas, Fadya Binyameen, Tomasz Jan Nowakowski, Arnold R. Kriegstein, Stephan Sanders, Matthew W. State, Katherine S. Pollard et al. · 2020 · Cell
  48. Long-lasting effects of minocycline on behavior in young but not adult Fragile X mice.
    Dansie, L.E., Phommahaxay, K., Okusanya, A.G., Uwadia, J., Huang, M., Rotschafer, S.E., Razak, K.A., Ethell, D.W., Ethell, I.M. · 2013 · Neuroscience
  49. Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
    Orosco, Lori A., Ross, Adam P., Cates, Staci L., Scott, Sean E., Wu, Dennis, Sohn, Jiho, Pleasure, David, Pleasure, Samuel J., Adamopoulos, Iannis E., Zarbalis, Konstantinos S · 2014 · Nature Communications
  50. GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
    Alondra Schweizer Burguete, Sandra Almeida, Fen‐Biao Gao, Robert Gordon Kalb, Michael R. Akins, Nancy M. Bonini · 2015 · eLife
  51. Staufen2 Regulates Neuronal Target RNAs
    Jacki E. Heraud-Farlow, Tejaswini Sharangdhar, Xiao Li, Philipp Pfeifer, Stefanie Tauber, Denise Orozco, Alexandra Hörmann, Sabine Thomas, Anetta Bakosova, Ashley Farlow et al. · 2013 · Cell Reports
  52. Sex differences in brain plasticity: a new hypothesis for sex ratio bias in autism
    Laurent Mottron, Pauline Duret, Sophia Mueller, Robert Davis Moore, Baudouin Forgeot d’Arc, Sébastien Jacquemont, Lan Xiong · 2015 · Molecular Autism
  53. Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome
    Till, Sally M., Wijetunge, Lasani S., Seidel, Viktoria G., Harlow, Emily, Wright, Ann K., Bagni, Claudia, Contractor, Anis, Gillingwater, Thomas H., Kind, Peter C. · 2012 · Human Molecular Genetics
  54. Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice
    Emanuela Santini, Thu N. Huynh, Francesco Longo, So Yeon Koo, Edward S. Mojica, Laura D’Andrea, Claudia Bagni, Eric Klann · 2017 · Science Signaling
  55. Identification of RNA-binding protein targets with HyperTRIBE
    Reazur Rahman, Weijin Xu, Hua Jin, Michael Rosbash · 2018 · Nature Protocols
  56. The function of RNA-binding proteins at the synapse: implications for neurodegeneration
    Chantelle F. Sephton, Gang Yu · 2015 · Cellular and Molecular Life Sciences
  57. Group 1 Metabotropic Glutamate Receptor Function and Its Regulation of Learning and Memory in the Aging Brain
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  58. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway
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  59. The Therapeutic Potential of Insulin-Like Growth Factor-1 in Central Nervous System Disorders
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  60. Emerging roles for MEF2 in brain development and mental disorders
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  61. The GABAAreceptor is an FMRP target with therapeutic potential in fragile X syndrome
    Sien Braat, Charlotte D’Hulst, Inge Heulens, Silvia De Rubeis, Edwin Mientjes, David Lee Nelson, Rob Willemsen, Claudia Bagni, Debby Van Dam, Peter Paul De Deyn et al. · 2015 · Cell Cycle
  62. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP
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  63. Expression of fragile X mental retardation protein in neurons and glia of the developing and adult mouse brain.
    Gholizadeh, Shervin, Halder, Sebok Kumar, Hampson, David R · 2015 · Brain Research
  64. FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
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  65. Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
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  66. Arginine methylation of RNA‐binding proteins regulates cell function and differentiation
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  67. Structural-functional connectivity deficits of neocortical circuits in the Fmr1 −/y mouse model of autism
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  68. Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders
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  69. Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions
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  70. Novel West syndrome candidate genes in a Chinese cohort
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  71. FMRP phosphorylation modulates neuronal translation through YTHDF1
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  72. The Structural Basis for RNA Selectivity by the IMP Family of RNA-Binding Proteins
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  73. Biallelic Mutations in<i>TSC2</i>Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons
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  74. Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome
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  75. Fragile X Syndrome: From Molecular Aspect to Clinical Treatment
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  76. RNA–protein interactions in vivo: global gets specific
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  77. Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits
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  78. Progress in the Genetics of Polygenic Brain Disorders: Significant New Challenges for Neurobiology
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  79. Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models
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  80. A developmental, longitudinal investigation of autism phenotypic profiles in fragile X syndrome
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  81. Monitoring Cell-Type–Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress
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  82. Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
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  83. Presynaptic FMRP and Local Protein Synthesis Support Structural and Functional Plasticity of Glutamatergic Axon Terminals
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  85. A cellular handbook for collided ribosomes: Surveillance pathways and collision types
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  86. MyelStones: the executive roles of myelin basic protein in myelin assembly and destabilization in multiple sclerosis
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  87. Active Ribosome Profiling With RiboLace
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  88. Essential genetic findings in neurodevelopmental disorders
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  89. Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome
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  90. Defining genetically meaningful language and personality traits in relatives of individuals with fragile X syndrome and relatives of individuals with autism
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    Jung Hwan Kim, Xin Wang, Rosemary Coolon, Bing Ye · 2013 · Neuron
  92. RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome
    Ian M. Silverman, Fan Li, A Vinogradov Alexander, Loyal A. Goff, Cole Trapnell, John L. Rinn, Brian D. Gregory · 2014 · Genome biology
  93. Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome
    Brian E. Kalmbach, Daniel Johnston, Darrin H. Brager · 2015 · eNeuro
  94. Homeostatic synaptic plasticity as a metaplasticity mechanism — a molecular and cellular perspective
    Jie Li, Esther Park, Lei Ray Zhong, Lu Chen · 2018 · Current Opinion in Neurobiology
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  96. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk
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  99. First glimpses of the neurobiology of autism spectrum disorder
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