FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Darnell, Jennifer C., Van Driesche, Sarah J., Zhang, Chaolin, Hung, Ka Ying Sharon, Mele, Aldo, Fraser, Claire E., Stone, Elizabeth F., Chen, Cynthia +5 more·2011·Cell

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Items 101–200 of 1,007

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    Kwang‐Mook Jung, Marja D. Sepers, Christopher M. Henstridge, Olivier Lassalle, Daniela N. Neuhofer, Henry G. S. Martin, Melanie R. Ginger, Andreas Frick, Nicholas Vincent DiPatrizio, Ken Mackie et al. · 2012 · Nature Communications
  2. EBV and human microRNAs co‐target oncogenic and apoptotic viral and human genes during latency
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  3. Single β-Actin mRNA Detection in Neurons Reveals a Mechanism for Regulating Its Translatability
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  4. Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity
    James P. Gilbert, Heng‐Ye Man · 2017 · Frontiers in Cellular Neuroscience
  5. Tunable protein synthesis by transcript isoforms in human cells
    Floor, Stephen N, Doudna, Jennifer A · 2016 · eLife
  6. G‐quadruplexes in RNA biology
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  7. The discovery of integrated gene networks for autism and related disorders
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  8. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
    Moore, Michael J, Zhang, Chaolin, Gantman, Emily Conn, Mele, Aldo, Darnell, Jennifer C, Darnell, Robert B · 2014 · Nature Protocols
  9. Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions
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  11. Monosomes actively translate synaptic mRNAs in neuronal processes
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  12. Germline Chd8 haploinsufficiency alters brain development in mouse
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  13. Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
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  14. Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes
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  15. Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models
    Martínez‐Cerdeño, Verónica · 2017 · Developmental Neurobiology
  16. The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability
    Singh, Tarjinder, Walters, James T R, Johnstone, Mandy, Curtis, David, Suvisaari, Jaana, Torniainen, Minna, Rees, Elliott, Iyegbe, Conrad, Blackwood, Douglas, McIntosh, Andrew M et al. · 2017 · Nature Genetics
  17. Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome
    Ronesi, Jennifer A, Collins, Katie A, Hays, Seth A, Tsai, Nien-Pei, Guo, Weirui, Birnbaum, Shari G, Hu, Jia-Hua, Worley, Paul F, Gibson, Jay R, Huber, Kimberly M · 2012 · Nature Neuroscience
  18. Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABA <sub>B</sub> Receptors with Arbaclofen
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  19. Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome
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  20. Copy number variation in schizophrenia in Sweden
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  22. The Developmental Switch in GABA Polarity Is Delayed in Fragile X Mice
    He, Qionger, Nomura, Toshihiro, Xu, Jian, Contractor, Anis · 2014 · The Journal of Neuroscience
  23. Fragile X mental retardation protein and synaptic plasticity
    Michael S. Sidorov, Benjamin D. Auerbach, Mark F. Bear · 2013 · Molecular Brain
  24. TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
    Aoife McMahon, Reazur Rahman, Hua Jin, James L. Shen, Allegra Fieldsend, Weifei Luo, Michael Rosbash · 2016 · Cell
  25. Targeting the endocannabinoid system in the treatment of fragile X syndrome
    Busquets-Garcia, Arnau, Gomis-González, Maria, Guegan, Thomas, Agustín-Pavón, Carmen, Pastor, Antoni, Mato, Susana, Pérez-Samartín, Alberto, Matute, Carlos, de la Torre, Rafael, Dierssen, Mara et al. · 2013 · Nature Medicine
  26. Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts
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  27. Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders
    Samuel Heyes, Wendy S. Pratt, Elliott Rees, Shehrazade Dahimène, Laurent Ferron, Michael John Owen, ANNETTE C. DOLPHIN · 2015 · Progress in Neurobiology
  28. Sensitive and critical periods during neurotypical and aberrant neurodevelopment: A framework for neurodevelopmental disorders
    Rhiannon M. Meredith · 2014 · Neuroscience & Biobehavioral Reviews
  29. An epigenetic framework for neurodevelopmental disorders: From pathogenesis to potential therapy
    Millan, Mark J. · 2013 · Neuropharmacology
  30. Progress toward treatments for synaptic defects in autism
    Delorme, Richard, Ey, Elodie, Toro, Roberto, Leboyer, Marion, Gillberg, Christopher, Bourgeron, Thomas · 2013 · Nature Medicine
  31. Characterizing 5-methylcytosine in the mammalian epitranscriptome
    Shobbir Hussain, Jelena Aleksic, Sandra Blanco, Sabine Dietmann, Michaela Frye · 2013 · Genome biology
  32. Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets
    Feiran Zhang, Yunhee Kang, Mengli Wang, Yujing Li, Tianlei Xu, Wei Yang, Hongjun Song, Hao Wu, Qiang Shu, Peng Jin · 2018 · Human Molecular Genetics
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    Stein, Jason L., de la Torre-Ubieta, Luis, Tian, Yuan, Parikshak, Neelroop N., Hernández, Israel A., Marchetto, Maria C., Baker, Dylan K., Lu, Daning, Hinman, Cassidy R., Lowe, Jennifer K. et al. · 2014 · Neuron
  34. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
    Ince-Dunn, Gulayse, Okano, Hirotaka J., Jensen, Kirk B., Park, Woong-Yang, Zhong, Ru, Ule, Jernej, Mele, Aldo, Fak, John J., Yang, ChingWen, Zhang, Chaolin et al. · 2012 · Neuron
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    Jun Cho, Hyeshik Chang, S. Chul Kwon, Baekgyu Kim, Yoosik Kim, Junho Choe, Minju Ha, Yoon Ki Kim, V. Narry Kim · 2012 · Cell
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    Maria P. Ivshina, Paul F. Lasko, Joel D. Richter · 2014 · Annual Review of Cell and Developmental Biology
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    Harrington, Adam J, Raissi, Aram, Rajkovich, Kacey, Berto, Stefano, Kumar, Jaswinder, Molinaro, Gemma, Raduazzo, Jonathan, Guo, Yuhong, Loerwald, Kris, Konopka, Genevieve et al. · 2016 · eLife
  38. The new (dis)order in RNA regulation
    Aino I. Järvelin, Marko Noerenberg, Ilan Davis, Alfredo Castelló · 2016 · Cell Communication and Signaling
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    Andrew S. Allen, Susannah T. Bellows, Samuel Frank Berkovic, Joshua Bridgers, Rosemary Burgess, Gianpiero L. Cavalleri, Seo‐Kyung Chung, Patrick Cossette, Norman Delanty, Dennis Dlugos et al. · 2017 · The Lancet Neurology
  40. Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation
    Ishimura, Ryuta, Nagy, Gabor, Dotu, Ivan, Chuang, Jeffrey H, Ackerman, Susan L · 2016 · eLife
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    Virpi Leppä, Stephanie N. Kravitz, Christa Lese Martin, Joris Andrieux, Cédric Le Caignec, Dominique Martin‐Coignard, Christina T. DyBuncio, Stephan Sanders, Jennifer K. Lowe, Rita M. Cantor et al. · 2016 · The American Journal of Human Genetics
  42. G‐quadruplexes: Emerging roles in neurodegenerative diseases and the non‐coding transcriptome
    Roberto Simone, Pietro Fratta, Stephen Neidle, Gary N. Parkinson, Adrian M. Isaacs · 2015 · FEBS Letters
  43. Heterogeneity and specialized functions of translation machinery: from genes to organisms
    Naomi R. Genuth, Maria Barna · 2018 · Nature Reviews Genetics
  44. Widespread RNA editing dysregulation in brains from autistic individuals
    Stephen S. Tran, Hyun-Ik Jun, Jae Hoon Bahn, Adel Azghadi, Gokul Ramaswami, Eric L. Van Nostrand, Thai B. Nguyen, Yun-Hua Esther Hsiao, Chang‐Hoon Lee, Gabriel A. Pratt et al. · 2018 · Nature Neuroscience
  45. Genotype to phenotype relationships in autism spectrum disorders
    Chang, Jonathan, Gilman, Sarah R, Chiang, Andrew H, Sanders, Stephan J, Vitkup, Dennis · 2015 · Nature Neuroscience
  46. Accurate de novo and transmitted indel detection in exome-capture data using microassembly
    Giuseppe Narzisi, Jason O'Rawe, Ivan H. Iossifov, Han Fang, Yoon-ha Lee, Zihua Wang, Yiyang Wu, Gholson J. Lyon, Michael H. Wigler, Michael C. Schatz · 2014 · Nature Methods
  47. The Gametic Synapse: RNA Transfer to the Bovine Oocyte1
    Angus D. Macaulay, Isabelle Gilbert, Julieta Caballero, Rodrigo da Silva Nunes Barreto, Éric Fournier, Prudencio Tossou, Marc‐André Sirard, Hugh J. Clarke, Édouard W. Khandjian, François J. Richard et al. · 2014 · Biology of Reproduction
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  49. The polygenic architecture of schizophrenia — rethinking pathogenesis and nosology
    Olav Bjerkehagen Smeland, Oleksandr Frei, Anders Martin Dale, Ole A. Andreassen · 2020 · Nature Reviews Neurology
  50. Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome
    Hoeffer, C. A., Sanchez, E., Hagerman, R. J., Mu, Y., Nguyen, D. V., Wong, H., Whelan, A. M., Zukin, R. S., Klann, E., Tassone, F. · 2012 · Genes, Brain and Behavior
  51. Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses
    Hyejung Won, Won Mah, Eunjoon Kim · 2013 · Frontiers in Molecular Neuroscience
  52. Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
    Guo-Liang Chew, Andrea Pauli, Alexander F. Schier · 2016 · Nature Communications
  53. ERK/MAPK signalling in the developing brain: Perturbations and consequences
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  54. Translating the genome in time and space: Specialized ribosomes, RNA regulons, and RNA-binding proteins
    Shi, Zhen, Barna, Maria · 2015 · Annual Review of Cell and Developmental Biology
  55. Pausing on Polyribosomes: Make Way for Elongation in Translational Control
    Joel D. Richter, Jeff M. Coller · 2015 · Cell
  56. The Unstable Repeats—Three Evolving Faces of Neurological Disease
    David Lee Nelson, Harry T. Orr, Stephen T. Warren · 2013 · Neuron
  57. Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes
    Gkogkas, Christos G., Khoutorsky, Arkady, Cao, Ruifeng, Jafarnejad, Seyed Mehdi, Prager-Khoutorsky, Masha, Giannakas, Nikolaos, Kaminari, Archontia, Fragkouli, Apostolia, Nader, Karim, Price, Theodore J. et al. · 2014 · Cell Reports
  58. Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder
    Lombardo, M V, Moon, H M, Su, J, Palmer, T D, Courchesne, E, Pramparo, T · 2018 · Molecular Psychiatry
  59. Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP
    Nikita Vasilyev, Anna Polonskaia, Jennifer Cordes Darnell, Robert B. Darnell, Dinshaw J. Patel, Alexander Serganov · 2015 · Proceedings of the National Academy of Sciences
  60. Transmission, Development, and Plasticity of Synapses
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  61. Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
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  62. Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder
    Wu, Ye E, Parikshak, Neelroop N, Belgard, T Grant, Geschwind, Daniel H · 2016 · Nature Neuroscience
  63. Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance
    Leonard K. Kaczmarek, Yalan Zhang · 2017 · Physiological Reviews
  64. Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
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  65. Translational control in cellular and developmental processes
    Jian Kong, Paul F. Lasko · 2012 · Nature Reviews Genetics
  66. Post-transcriptional regulation of gene expression and human disease
    Anita H. Corbett · 2018 · Current Opinion in Cell Biology
  67. The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment
    Donald C. Rojas · 2014 · Journal of Neural Transmission
  68. Human Models Are Needed for Studying Human Neurodevelopmental Disorders
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  69. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
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  70. Disome and Trisome Profiling Reveal Genome-wide Targets of Ribosome Quality Control
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  71. LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs
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  72. Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops
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  73. MicroRNA binding sites in the coding region of mRNAs: Extending the repertoire of post‐transcriptional gene regulation
    Anneke Brümmer, Jean Hausser · 2014 · BioEssays
  74. Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism
    Huber, Kimberly M., Klann, Eric, Costa-Mattioli, Mauro, Zukin, R. Suzanne · 2015 · The Journal of Neuroscience
  75. RNA transport and local translation in neurodevelopmental and neurodegenerative disease
    Fernandopulle, Michael S., Lippincott-Schwartz, Jennifer, Ward, Michael E. · 2021 · Nature Neuroscience
  76. RNA Protein Interaction in Neurons
    Darnell, Robert B. · 2013 · Annual Review of Neuroscience
  77. Reactivation of stalled polyribosomes in synaptic plasticity
    Tyson Ernst Graber, Sarah Hébert-Seropian, Arkady Khoutorsky, Alexandre David, Jonathan Wilson Yewdell, Jean‐Claude Lacaille, Wayne S. Sossin · 2013 · Proceedings of the National Academy of Sciences
  78. Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families
    Harripaul, R, Vasli, N, Mikhailov, A, Rafiq, M A, Mittal, K, Windpassinger, C, Sheikh, T I, Noor, A, Mahmood, H, Downey, S et al. · 2018 · Molecular Psychiatry
  79. Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice
    Wen, Teresa H, Afroz, Sonia, Reinhard, Sarah M, Palacios, Arnold R, Tapia, Kendal, Binder, Devin K, Razak, Khaleel A, Ethell, Iryna M · 2018 · Cerebral Cortex
  80. Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders
    Kwok‐On Lai, Nancy Y. Ip · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  81. Dendritic spine dysgenesis in autism related disorders
    Mary L. Phillips, Lucas D. Pozzo‐Miller · 2015 · Neuroscience Letters
  82. Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay
    Bozdagi, Ozlem, Tavassoli, Teresa, Buxbaum, Joseph D · 2013 · Molecular Autism
  83. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
    Tao Wang, Qian Pan, Lin Li, Keith E. Szulwach, Chun‐Xiao Song, Chuan He, Hao Wu, Stephen T. Warren, Peng Jin, Ranhui Duan et al. · 2012 · Human Molecular Genetics
  84. The functional organization of axonal mRNA transport and translation
    Irene Dalla Costa, Courtney N. Buchanan, M. D. Zdradzinski, Pabitra K Sahoo, Terika P. Smith, E. Thames, Amar N. Kar, J. Twiss · 2020 · Nature Reviews Neuroscience
  85. SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons
    Zaslavsky, Kirill, Zhang, Wen-Bo, McCready, Fraser P., Rodrigues, Deivid C., Deneault, Eric, Loo, Caitlin, Zhao, Melody, Ross, P. Joel, El Hajjar, Joelle, Romm, Asli et al. · 2019 · Nature Neuroscience
  86. Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains
    Madeleine R. Geisheker, Gabriel Heymann, Tianyun Wang, Bradley P. Coe, Tychele N. Turner, Holly A.F. Stessman, Kendra Hoekzema, Malin Kvarnung, Marie A Shaw, Kathryn L. Friend et al. · 2017 · Nature Neuroscience
  87. Low load for disruptive mutations in autism genes and their biased transmission
    Iossifov, Ivan, Levy, Dan, Allen, Jeremy, Ye, Kenny, Ronemus, Michael, Lee, Yoon-ha, Yamrom, Boris, Wigler, Michael · 2015 · Proceedings of the National Academy of Sciences
  88. De Novo Insertions and Deletions of Predominantly Paternal Origin Are Associated with Autism Spectrum Disorder
    Shan Dong, Michael F. Walker, Nicholas John Carriero, Michael J. DiCola, Arthur Jeremy Willsey, Adam Yongxin Ye, Zainulabedin Waqar, Luis Eduardo González, John D. Overton, Stephanie Frahm et al. · 2014 · Cell Reports
  89. Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder
    Atsushi Takata, Noriko Miyake, Yoshinori Tsurusaki, Ryoko Fukai, Satoko Miyatake, Eriko Koshimizu, Itaru Kushima, Takashi Okada, Mako Morikawa, Yota Uno et al. · 2018 · Cell Reports
  90. Genetics of glutamate and its receptors in autism spectrum disorder
    Sabah Nisar, Ajaz Ahmad Bhat, Tariq Masoodi, Sheema Hashem, Sabah Akhtar, Tayyiba Akbar Ali, Sara Amjad, Sanjeev Chawla, Puneet Bagga, Michael Paul Frenneaux et al. · 2022 · Molecular Psychiatry
  91. Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex
    Froylán Calderón de Anda, Ana Lúcia Rosário, Omer Durak, Tracy S. Tran, Johannes Gräff, Konstantinos Meletis, Damien Rei, Takahiro Soda, Ram Madabhushi, David D. Ginty et al. · 2012 · Nature Neuroscience
  92. Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders
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  93. Autism and the synapse
    Darius Ebrahimi‐Fakhari, Mustafa Şahin · 2015 · Current Opinion in Neurology
  94. Single-cell genomics and regulatory networks for 388 human brains
    Prashant S. Emani, Jason J. Liu, Declan Clarke, Matthew Jensen, Jonathan Warrell, Chirag Gupta, Ran Meng, Che-Yu Lee, Siwei Xu, Cagatay Dursun et al. · 2024 · Science
  95. A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies
    Yunhee Kang, Ying Zhou, Yujing Li, Yanfei Han, Jie Xu, Weibo Niu, Ziyi Li, Shiying Liu, Hao Feng, Wen Huang et al. · 2021 · Nature Neuroscience
  96. Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder
    Uddin, Mohammed, Tammimies, Kristiina, Pellecchia, Giovanna, Alipanahi, Babak, Hu, Pingzhao, Wang, Zhuozhi, Pinto, Dalila, Lau, Lynette, Nalpathamkalam, Thomas, Marshall, Christian R et al. · 2014 · Nature Genetics
  97. The DEAD-Box Protein Dhh1 Promotes Decapping by Slowing Ribosome Movement
    Thomas J. Sweet, Carrie Kovalak, Jeff M. Coller · 2012 · PLoS Biology
  98. Advances and challenges in the detection of transcriptome‐wide protein– RNA interactions
    Emily C. Wheeler, Eric L. Van Nostrand, Gene Wei-Ming Yeo · 2017 · Wiley Interdisciplinary Reviews - RNA
  99. High MMP-9 activity levels in fragile X syndrome are lowered by minocycline
    Dziembowska, Magdalena, Pretto, Dalyir I., Janusz, Aleksandra, Kaczmarek, Leszek, Leigh, Mary Jacena, Gabriel, Nielsen, Durbin‐Johnson, Blythe, Hagerman, Randi J., Tassone, Flora · 2013 · American Journal of Medical Genetics Part A
  100. Transactivation of programmed ribosomal frameshifting by a viral protein
    Yànhuá Lǐ, Emmely E. Treffers, Sawsan Napthine, Ali Taş, Longchao Zhu, Zhi Sun, Susanne Bell, Brian L. Mark, Peter A. van Veelen, Martijn J. van Hemert et al. · 2014 · Proceedings of the National Academy of Sciences