Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.211 · Cited by 35,890 · see citing works

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkn923 · Cited by 14,108 · see citing works

A new method for non-parametric multivariate analysis of variance

Anderson, M. J. (2001) · Austral Ecology · doi:10.1111/j.1442-9993.2001.01070.pp.x · Cited by 13,828 · see citing works

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Trapnell, C., Roberts, A., Goff, L. A., Pertea, G. M., Kim, D., Kelley, D. R., Pimentel, H., Salzberg, S. L., Rinn, J. L., & Pachter, L. S. (2012) · Nature Protocols · doi:10.1038/nprot.2012.016 · Cited by 11,930 · see citing works

Global quantification of mammalian gene expression control

Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., & Selbach, M. (2011) · Nature · doi:10.1038/nature10098 · Cited by 6,566 · cited 1× · see citing works

FITTING MULTIVARIATE MODELS TO COMMUNITY DATA: A COMMENT ON DISTANCE-BASED REDUNDANCY ANALYSIS

McArdle, B. H., & Anderson, M. J. (2001) · Ecology · doi:10.1890/0012-9658(2001)082[0290:fmmtcd]2.0.co;2 · Cited by 4,001 · see citing works

The mechanism of eukaryotic translation initiation and principles of its regulation

Jackson, R. J., Hellen, C. U. T., & Pestova, T. V. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2838 · Cited by 2,759 · see citing works

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

Darnell, J. C., Van Driesche, S. J., Zhang, C., Hung, K. Y. S., Mele, A., Fraser, C. E., Stone, E. F., Chen, C., Fak, J. J., Chi, S. W., et al. (2011) · Cell · doi:10.1016/j.cell.2011.06.013 · Cited by 2,072 · see citing works

Reinitiation involving upstream ORFs regulates <i>ATF4</i> mRNA translation in mammalian cells

Vattem, K. M., & Wek, R. C. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400541101 · Cited by 1,696 · see citing works

Neuronal subtype specification in the cerebral cortex

Molyneaux, B. J., Arlotta, P., Menezes, J. R. L., & Macklis, J. D. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2151 · Cited by 1,632 · see citing works

Evolution of the neocortex: a perspective from developmental biology

Rakic, P. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2719 · Cited by 1,565 · see citing works

Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage

Gorski, J. A., Talley, T., Qiu, M. S., Puelles, L., Rubenstein, J. L. R., & Jones, K. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06309.2002 · Cited by 1,367 · see citing works

Transcriptional landscape of the prenatal human brain

Miller, J. A., Ding, S.-L., Sunkin, S. M., Smith, K. A., Ng, L., Szafer, A., Ebbert, A., Riley, Z. L., Royall, J. J., Aiona, K., et al. (2014) · Nature · doi:10.1038/nature13185 · Cited by 1,325 · see citing works

RNA regulons: coordination of post-transcriptional events

Keene, J. D. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2111 · Cited by 1,321 · see citing works

Development of the human cerebral cortex: Boulder Committee revisited

Bystron, I., Blakemore, C., & Rakic, P. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2252 · Cited by 977 · see citing works

Molecular logic of neocortical projection neuron specification, development and diversity

Greig, L. C., Woodworth, M. B., Galazo, M. J., Padmanabhan, H., & Macklis, J. D. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3586 · Cited by 863 · see citing works

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

Lebedeva, S., Jens, M., Theil, K., Schwanhäusser, B., Selbach, M., Landthaler, M., & Rajewsky, N. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.06.008 · Cited by 716 · see citing works

Translational control in biology and medicine

Mathews, M. B., Sonenberg, N., & Hershey, J. W. B. (2007) · Cited by 661 · see citing works

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

Mukherjee, N., Corcoran, D. L., Nusbaum, J. D., Reid, D. W., Georgiev, S., Hafner, M., Ascano, M., Tuschl, T., Ohler, U., & Keene, J. D. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.06.007 · Cited by 654 · see citing works

Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex

Kwan, K. Y., Šestan, N., & Anton, E. S. (2012) · Development · doi:10.1242/dev.069963 · Cited by 388 · see citing works

The determination of projection neuron identity in the developing cerebral cortex

Leone, D. P., Srinivasan, K., Chen, B., Alcamo, E., & McConnell, S. K. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.05.006 · Cited by 382 · see citing works

HuR function in disease

Srikantan, S. (2012) · Frontiers in Bioscience · doi:10.2741/3921 · Cited by 353 · see citing works

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

Rašin, M.-R., Gazula, V., Breunig, J. J., Kwan, K. Y., Johnson, M. B., Liu‐Chen, S., Li, H.-S., Jan, L. Y., Jan, Y. N., RAKIC, P. T., et al. (2007) · Nature Neuroscience · doi:10.1038/nn1924 · Cited by 316 · see citing works

Phosphorylation of eIF2 Directs ATF5 Translational Control in Response to Diverse Stress Conditions

Zhou, D., Palam, L. R., Jiang, L., Narasimhan, J., Staschke, K. A., & Wek, R. C. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m708530200 · Cited by 312 · see citing works

A Transcriptomic Atlas of Mouse Neocortical Layers

Belgard, T. G., Marques, A. C., Oliver, P. L., Abaan, H. Ö., Sirey, T., Hoerder‐Suabedissen, A., García‐Moreno, F., Molnár, Z., Margulies, E. H., & Ponting, C. P. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.039 · Cited by 273 · see citing works

Cortical Axon Guidance by the Glial Wedge during the Development of the Corpus Callosum

Shu, T., & Richards, L. J. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02749.2001 · Cited by 265 · see citing works

HuR as a Negative Posttranscriptional Modulator in Inflammation

Katsanou, V., Papadaki, O., Milatos, S., Blackshear, P. J., Anderson, P., Kollias, G. A., & Kontoyiannis, D. L. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.08.007 · Cited by 236 · see citing works

The RNA-Binding Protein Elavl1/HuR Is Essential for Placental Branching Morphogenesis and Embryonic Development

Katsanou, V., Milatos, S., Yiakouvaki, A., Sgantzis, N., Kotsoni, A., Alexiou, M. V., Harokopos, V., Aidinis, V., Hemberger, M., & Kontoyiannis, D. L. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01393-08 · Cited by 204 · see citing works

Translational control in cellular and developmental processes

Kong, J., & Lasko, P. F. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3184 · Cited by 189 · see citing works

RNA Protein Interaction in Neurons

Darnell, R. B. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062912-114322 · Cited by 181 · see citing works

The exon junction complex component Magoh controls brain size by regulating neural stem cell division

Silver, D. L., Watkins‐Chow, D. E., Schreck, K. C., Pierfelice, T. J., Larson, D. M., Burnetti, A., Liaw, H., Myung, K., Walsh, C. A., Gaiano, N., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2527 · Cited by 177 · see citing works

Nova2 Regulates Neuronal Migration through an RNA Switch in Disabled-1 Signaling

Yano, M., Hayakawa-Yano, Y., Mele, A., & Darnell, R. B. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.007 · Cited by 176 · see citing works

Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae.

Ramírez, M., Wek, R. C., & Hinnebusch, A. G. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3027 · Cited by 169 · see citing works

Transient Neuronal Populations Are Required to Guide Callosal Axons: A Role for Semaphorin 3C

Niquille, M., Garel, S., Mann, F., Hornung, J., Otsmane, B., Chevalley, S., Parras, C. M., Guillemot, F., Gaspar, P., Yanagawa, Y., et al. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000230 · Cited by 158 · see citing works

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex

Kwan, K. Y., Lam, M. M. S., Johnson, M. B., Dube, U., Shim, S., Rašin, M.-R., Sousa, A. M. M., Fertuzinhos, S., Chen, J.-G., Arellano, J. I., et al. (2012) · Cell · doi:10.1016/j.cell.2012.02.060 · Cited by 137 · see citing works

Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing

Ayoub, A. E., Oh, S., Xie, Y., Leng, J., Cotney, J., Dominguez, M. H., Noonan, J. P., & Rakic, P. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112213108 · Cited by 129 · see citing works

Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex

Chou, S., Pérez‐García, C. G., Kroll, T. T., & O’Leary, D. D. M. (2009) · Nature Neuroscience · doi:10.1038/nn.2427 · Cited by 125 · see citing works

Ribosomal Slowdown Mediates Translational Arrest during Cellular Division

Sivan, G., Kedersha, N., & Elroy‐Stein, O. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00798-07 · Cited by 120 · see citing works

Asymmetric Segregation of the Double-Stranded RNA Binding Protein Staufen2 during Mammalian Neural Stem Cell Divisions Promotes Lineage Progression

Kusek, G., Campbell, M., Doyle, F., Tenenbaum, S. A., Kiebler, M. A., & Temple, S. (2012) · Cell stem cell · doi:10.1016/j.stem.2012.06.006 · Cited by 111 · see citing works

FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development.

Saffary, R., & Xie, Z. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4854-10.2011 · Cited by 103 · see citing works

Prenatal Deletion of the RNA-Binding Protein HuD Disrupts Postnatal Cortical Circuit Maturation and Behavior

DeBoer, E. M., Azevedo, R., Vega, T. A., Brodkin, J., Akamatsu, W., Okano, H., Wagner, G. C., & Rasin, M.-R. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.3703-13.2014 · Cited by 72 · see citing works

Eukaryotic Polyribosome Profile Analysis

Esposito, A. M., Mateyak, M. K., He, D., Lewis, M., Sasikumar, A. N., Hutton, J., Copeland, P. R., & Kinzy, T. G. (2010) · Journal of Visualized Experiments · doi:10.3791/1948 · Cited by 54 · see citing works

Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons

DeBoer, E., Kraushar, M. L., Hart, R. P., & Rašin, M. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.05.042 · Cited by 45 · see citing works

Ribosomes take control

Barna, M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1218764110 · Cited by 26 · see citing works

Stabilization ofDll1mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis

García-Domínguez, D. J., Morello, D., Cisneros, E., Kontoyiannis, D. L., & Frade, J. M. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e10-10-0808 · Cited by 25 · see citing works

Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain

Xu, R., Li, X., Boreland, A. J., Posyton, A., Kwan, K. Y., Hart, R. P., & Jiang, P. (2020) · Nature Communications · doi:10.1038/s41467-020-15411-9 · Cited by 190 · see citing works

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

Xu, R., Brawner, A. T., Li, S., Liu, J.-J., Kim, H., Xue, H., Pang, Z. P., Kim, W.-Y., Hart, R. P., Liu, Y., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.04.014 · Cited by 193 · see citing works

Emerging Evidence of Translational Control by AU-Rich Element-Binding Proteins

Otsuka, H., Fukao, A., Funakami, Y., Duncan, K. E., & Fujiwara, T. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00332 · Cited by 100 · see citing works

Downregulation of ribosome biogenesis during early forebrain development

Chau, K. F., Shannon, M. L., Fame, R. M., Fonseca, E., Mullan, H., Johnson, M. B., Sendamarai, A. K., Springel, M. W., Laurent, B., & Lehtinen, M. K. (2018) · eLife · doi:10.7554/elife.36998 · Cited by 94 · see citing works

ELAVL2-regulated transcriptional and splicing networks in human neurons link neurodevelopment and autism

Berto, S., Usui, N., Konopka, G., & Fogel, B. L. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw110 · Cited by 80 · see citing works

RNA on the brain: emerging layers of post‐transcriptional regulation in cerebral cortex development

Lennox, A. L., Mao, H., & Silver, D. L. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.290 · Cited by 70 · see citing works

Post‐transcriptional regulation in corticogenesis: how RNA‐binding proteins help build the brain

Pilaz, L., & Silver, D. L. (2015) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1289 · Cited by 71 · see citing works

Genome-wide, integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autismPreprint

Chen, Y., Chen, C.-Y., Mai, T., Chuang, C.-F., Chen, Y., Gupta, S. K., Yen, L., Wang, Y.-D., & Chuang, T. (2020) · Genome Research · doi:10.1101/gr.255463.119 · Cited by 67 · see citing works

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

Simone, R., Javad, F., Emmett, W., Wilkins, O. G., Almeida, F., Barahona‐Torres, N., Zarȩba-Pasławska, J., Ehteramyan, M., Zuccotti, P., Modelska, A., et al. (2021) · Nature · doi:10.1038/s41586-021-03556-6 · Cited by 69 · see citing works

A critical period of translational control during brain development at codon resolution

Harnett, D., Ambrozkiewicz, M. C., Zinnall, U., Rusanova, A., Borisova, E., Drescher, A. N., Couce-Iglesias, M., Villamil, G., Dannenberg, R., Imami, K., et al. (2022) · Nature Structural &amp; Molecular Biology · doi:10.1038/s41594-022-00882-9 · Cited by 68 · see citing works

Novel RNA-binding activity of MYF5 enhancesCcnd1/Cyclin D1mRNA translation during myogenesis

Panda, A. C., Abdelmohsen, K., Martindale, J. L., Germanio, C. D., Yang, X., Grammatikakis, I., Noh, J. H., Zhang, Y., Lehrmann, E., Dudekula, D. B., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw023 · Cited by 65 · see citing works

Targeting the Multifaceted HuR Protein, Benefits and Caveats

Zucal, C., D’Agostino, V., Loffredo, R., Mantelli, B., Thongon, N., Lal, P., Latorre, E., & Provenzani, A. (2015) · Current Drug Targets · doi:10.2174/1389450116666150223163632 · Cited by 65 · see citing works

Translating neural stem cells to neurons in the mammalian brain

Zahr, S. K., Kaplan, D. R., & Miller, F. D. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-019-0411-9 · Cited by 63 · see citing works

Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein–protein interaction network

Li, Y., Collins, M. A., An, J., Geiser, R., Tegeler, T. J., Tsantilas, K. A., Garcia, K., Pirrotte, P., & Bowser, R. P. (2016) · Brain Research · doi:10.1016/j.brainres.2016.02.047 · Cited by 61 · see citing works

Splicing regulation in brain and testis: common themes for highly specialized organs

Naro, C., Cesari, E., & Sette, C. (2021) · Cell Cycle · doi:10.1080/15384101.2021.1889187 · Cited by 58 · see citing works

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

Popovitchenko, T., Park, Y., Page, N. F., Luo, X., Krsnik, Z., Liu, Y., Salamon, I., Stephenson, J. D., Kraushar, M. L., Volk, N. L., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15412-8 · Cited by 55 · see citing works

Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model

Hoye, M. L., Calviello, L., Poff, A., Ejimogu, E., Newman, C. R., Montgomery, M. D., Ou, J., Floor, S. N., & Silver, D. L. (2022) · eLife · doi:10.7554/elife.78203 · Cited by 54 · see citing works

Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes

Kraushar, M. L., Viljetić, B., Wijeratne, H. R. S., Thompson, K., Jiao, X., Pike, J. W., Medvedeva, V. P., Groszer, M., Kiledjian, M., Hart, R. P., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0601-15.2015 · Cited by 52 · see citing works

CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype

Lal, S., Cheung, E. C., Zarei, M., Preet, R., Chand, S. N., Mambelli-Lisboa, N. C., Romeo, C., Stout, M. C., Londin, E. R., Goetz, A. B., et al. (2017) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-16-0361 · Cited by 52 · see citing works

Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

Grassi, E., Santoro, R., Umbach, A., Grosso, A., Oliviero, S., Neri, F., Conti, L., Ala, U., Provero, P., Cunto, F. D., et al. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00518 · Cited by 54 · see citing works

Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit

Kraushar, M. L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M. C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C. H., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2020.11.037 · Cited by 49 · see citing works

Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3′ UTR Landscape in Drosophila

Lü, W., Lee, S., Majumdar, S., Zhang, B., Sanfilippo, P., Joseph, B. J., Miura, P., Soller, M., & Lai, E. C. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.09.007 · Cited by 46 · see citing works

Transcriptional and Post-Transcriptional Mechanisms of the Development of Neocortical Lamination

Popovitchenko, T., & Rašin, M. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00102 · Cited by 45 · see citing works

ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

Lee, S., Wei, L., Zhang, B., Goering, R., Majumdar, S., Wen, J., Taliaferro, J. M., & Lai, E. C. (2021) · PLoS Genetics · doi:10.1371/journal.pgen.1009439 · Cited by 44 · see citing works

HuR (Elavl1) and HuB (Elavl2) Stabilize Matrix Metalloproteinase-9 mRNA During Seizure-Induced Mmp-9 Expression in Neurons

Żybura-Broda, K., Wolder-Gontarek, M., Ambrożek-Latecka, M., Choros, A., Bogusz, A., Wilemska, J., & Rylski, M. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00224 · Cited by 44 · see citing works

Developmental and Behavioral Phenotypes in a Mouse Model of DDX3X Syndrome

Boitnott, A., García-Forn, M., Ung, D. C., Niblo, K., Mendonca, D., Park, Y., Flores, M., Maxwell, S., Ellegood, J., Qiu, L. R., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.05.027 · Cited by 41 · see citing works

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR

Battaglia-Hsu, S.-F., Ghemrawi, R., Coelho, D., Dreumont, N., Mosca, P., Hergalant, S., Gauchotte, G., Sequeira, J. M., Ndiongue, M., Houlgatte, R., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky634 · Cited by 41 · see citing works

Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses

Yan, T., Ding, F. H., & Zhao, Y. (2019) · Hereditas · doi:10.1186/s41065-019-0101-0 · Cited by 40 · see citing works

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex

Salamon, I., Park, Y., Miškić, T., Kopić, J., Matteson, P. G., Page, N. F., Roque, A., McAuliffe, G., Favate, J. S., García-Forn, M., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41730-8 · Cited by 37 · see citing works

Understanding Neurodevelopmental Disorders: The Promise of Regulatory Variation in the 3′UTRome

Wanke, K. A., Devanna, P., & Vernes, S. C. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.11.006 · Cited by 38 · see citing works

Long noncoding RNAs: Central to nervous system development

Hart, R. P., & Goff, L. A. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.06.001 · Cited by 36 · see citing works

HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models

Assoni, G., Pietra, V. L., Digilio, R., Ciani, C., Licata, N. V., Micaelli, M., Facen, E., Tomaszewska, W., Cerofolini, L., Pérez‐Ràfols, A., et al. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114088 · Cited by 36 · see citing works

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

Popovitchenko, T., Thompson, K., Viljetić, B., Jiao, X., Kontonyiannis, D. L., Kiledjian, M., Hart, R. P., & Rašin, M. R. (2016) · Scientific Reports · doi:10.1038/srep28998 · Cited by 35 · see citing works

Cooperativity in RNA–protein interactions: the complex is more than the sum of its partners

Achsel, T., & Bagni, C. (2016) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2016.06.007 · Cited by 35 · see citing works

Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis

Wang, Y., Guo, Y., Tang, C., Han, X. W., Xu, M., Sun, J., Zhao, Y., Zhang, Y., Wang, M., Cao, X., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.10.127 · Cited by 35 · see citing works

Moving messages in the developing brain—emerging roles for mRNA transport and local translation in neural stem cells

Pilaz, L., & Silver, D. L. (2017) · FEBS Letters · doi:10.1002/1873-3468.12626 · Cited by 32 · see citing works

Decoding mixed messages in the developing cortex: translational regulation of neural progenitor fate

Hoye, M. L., & Silver, D. L. (2020) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.10.001 · Cited by 31 · see citing works

Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice

Herrlinger, S. A., Shao, Q., Yang, M., Chang, Q., Liu, Y., Pan, X., Yin, H., Xie, L., & Chen, J.-F. (2019) · Development · doi:10.1242/dev.173765 · Cited by 30 · see citing works

Protein translation rate determines neocortical neuron fate

Borisova, E. V., Newman, A. G., Couce-Iglesias, M., Dannenberg, R., Schaub, T., Qin, B., Rusanova, A., Brockmann, M. M., Koch, J., Daniels, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49198-w · Cited by 28 · see citing works

Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation

Christodoulou‐Vafeiadou, E., Ioakeimidis, F., Ανδρεάδου, Μ., Giagkas, G., Stamatakis, G. M., Reczko, M., Samiotaki, M. K., Papanastasiou, A. D., Karakasiliοtis, I., & Kontoyiannis, D. L. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02732 · Cited by 27 · see citing works

Recapitulating and reversing human brain ribosomopathy defects via the maladaptive integrated stress response

Zhang, W., Zhang, M., Ma, L., Jariyasakulroj, S., Chang, Q., Lin, Z., Lu, Z., & Chen, J. (2024) · Science Advances · doi:10.1126/sciadv.adk1034 · Cited by 22 · see citing works

The regulatory landscape of 5′ UTRs in translational control during zebrafish embryogenesis

Reimão-Pinto, M. M., Castillo-Hair, S. M., Seelig, G., & Schier, A. F. (2025) · Developmental Cell · doi:10.1016/j.devcel.2024.12.038 · Cited by 21 · see citing works

Making sense of mRNA landscapes: Translation control in neurodevelopment

Park, Y., Page, N. F., Salamon, I., Li, D., & Rašin, M. (2021) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1674 · Cited by 21 · see citing works

Studying the Translatome with Polysome Profiling

Zuccotti, P., & Modelska, A. (2016) · Methods in Molecular Biology · doi:10.1007/978-1-4939-3067-8_4 · Cited by 20 · see citing works

The Role of Dynamic miRISC During Neuronal Development

Nawalpuri, B., Ravindran, S., & Muddashetty, R. S. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00008 · Cited by 19 · see citing works

A Bivalent Securinine Compound SN3-L6 Induces Neuronal Differentiation via Translational Upregulation of Neurogenic Transcription Factors

Liao, Y., Zhuang, X., Huang, X., Peng, Y., Ma, X., Huang, Z.-X., Liu, F., Xu, J., Wang, Y., Chen, W., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00290 · Cited by 20 · see citing works

Roles of Embryonic Lethal Abnormal Vision-Like RNA Binding Proteins in Cancer and Beyond

Cai, H., Zheng, D., Yao, Y., Yang, L., Huang, X., & Wang, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.847761 · Cited by 18 · see citing works

Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes

Froberg, J. E., Durak, O., & Macklis, J. D. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112995 · Cited by 18 · see citing works

The frontier of RNA metamorphosis and ribosome signature in neocortical development

Kraushar, M. L., Popovitchenko, T., Volk, N. L., & Rašin, M. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.02.003 · Cited by 18 · see citing works

Extracellular microRNAs as messengers in the central and peripheral nervous system

Scott, H. (2017) · Neuronal Signaling · doi:10.1042/ns20170112 · Cited by 17 · see citing works

Experimental upregulation of developmentally downregulated ribosomal protein large subunits 7 and 7A promotes axon regeneration after injury in vivo

Xing, J., Theune, W. C., Łukomska, A., Frost, M. P., Damania, A., & Trakhtenberg, E. F. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114510 · Cited by 17 · see citing works

The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain

Kanemitsu, Y., Fujitani, M., Fujita, Y., Zhang, S., Su, Y., Kawahara, Y., & Yamashita, T. (2017) · Scientific Reports · doi:10.1038/s41598-017-01317-y · Cited by 16 · see citing works

Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells

Techasintana, P., Davis, J. W., Gubin, M. M., Magee, J., & Atasoy, U. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129321 · Cited by 15 · see citing works

Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae

Liang, K.-J., Yueh, L.-Y., Hsu, N.-H., Lai, J.-S., & Lo, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235941 · Cited by 15 · see citing works

Lessons from studying the AU-rich elements in chronic inflammation and autoimmunity

Lourou, N., Gavriilidis, M., & Kontoyiannis, D. L. (2019) · Journal of Autoimmunity · doi:10.1016/j.jaut.2019.102334 · Cited by 15 · see citing works

Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming

Papadimitriou, E., & Thomaidou, D. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.390976 · Cited by 13 · see citing works

Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons

Zhao, Y., He, X., Song, Z.-F., Guo, Y., Zhang, Y.-N., Yu, H., He, Z., Xiong, W., Guo, W., & Zhu, X.-J. (2020) · Development · doi:10.1242/dev.183509 · Cited by 12 · see citing works

Evolution of the Neocortex Through RNA-Binding Proteins and Post-transcriptional Regulation

Salamon, I., & Rašin, M. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.803107 · Cited by 11 · see citing works

Translational Control during Mammalian Neocortex Development and Postembryonic Neuronal Function

Oliveira, N. C. M., Lins, É. M., Massirer, K. B., & Bengtson, M. H. (2020) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2020.09.006 · Cited by 11 · see citing works

Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line

Lin, L., Swerdel, M. R., Lazaropoulos, M. P., Hoffman, G. S., Toro-Ramos, A. J., Wright, J., Lederman, H. M., Chen, J., Moore, J. C., & Hart, R. P. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.10.010 · Cited by 11 · see citing works

Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

Harb, K., Richter, M., Neelagandan, N., Magrinelli, E., Harfoush, H., Kuechler, K., Henis, M., Hermanns-Borgmeyer, I., de Anda, F. C., & Duncan, K. E. (2022) · eLife · doi:10.7554/elife.55199 · Cited by 11 · see citing works

Shank3 modulates Rpl3 expression and protein synthesis via mGlu5: implications for Phelan McDermid syndrome

Giona, F., Beretta, S., Zippo, A. G., Stefanoni, A., Tomasoni, Z., Vicidomini, C., Ponzoni, L., Sala, M., Jones, C. K., Conn, P. J., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02947-9 · Cited by 11 · see citing works

Tissue-wide cell-specific proteogenomic modeling reveals novel candidate risk genes in autism spectrum disorders

Torshizi, A. D., & Wang, K. (2022) · npj Systems Biology and Applications · doi:10.1038/s41540-022-00243-8 · Cited by 10 · see citing works

Multiple roles of PIWIL1 in mouse neocorticogenesisPreprint

Viljetić, B., Diao, L., Liu, J., Krsnik, Ž., Wijeratne, H. R. S., Kristopovich, R., Dutre-Clarke, M., Kraushar, M. L., Song, J., Xing, J., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/106070 · Cited by 10 · see citing works

Protein Synthesis and Translational Control in Neural Stem Cell Development and Neurogenesis

Mohammad, L., Wiseman, J., Erickson, S. E., & Yang, G. (2019) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190686307.013.21 · Cited by 8 · see citing works

Post‐transcriptional regulation of gene expression in neural stem cells

Kim, D. (2016) · Cell Biochemistry and Function · doi:10.1002/cbf.3181 · Cited by 7 · see citing works

Regulation of mRNA translation in stem cells; links to brain disorders.

Statoulla, E., Chalkiadaki, K., Karozis, D., & Gkogkas, C. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110166 · Cited by 8 · see citing works

mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development

Salamon, I., Palsule, G., Luo, X., Roque, A., Tucai, S., Khosla, I., Volk, N. L., Liu, W. J., Cui, H., Pozzo, V. D., et al. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab302 · Cited by 7 · see citing works

Peering at Brain Polysomes with Atomic Force Microscopy

Lunelli, L., Bernabò, P., Bolner, A., Vaghi, V., Marchioretto, M., & Viero, G. (2016) · Journal of Visualized Experiments · doi:10.3791/53851 · Cited by 8 · see citing works

Posttranscriptional and translational control of neurogenesis

Alsina, F. C., & Silver, D. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00028-x · Cited by 6 · see citing works

Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression

Weber, A. I., Parthasarathy, S., Borisova, E. V., Epifanova, E. A., Preußner, M., Rusanova, A., Ambrozkiewicz, M. C., Bessa, P., Newman, A. G., Müller, L., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad703 · Cited by 6 · see citing works

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling

Kedia, S., Erickson, S. L., & Yang, G. (2021) · Journal of Visualized Experiments · doi:10.3791/62088 · Cited by 5 · see citing works

A subpopulation of cortical neurons altered by mutations in the autism risk gene DDX3X

Flores, M., García-Forn, M., von Mueffling, A., Ola, P., Park, Y., Boitnott, A., & Rubeis, S. D. (2025) · Biology Open · doi:10.1242/bio.061854 · Cited by 5 · see citing works

Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion

Št́astná, M., Thomas, A., Germano, J. D. F., Pourpirali, S., Eyk, J. E. V., & Gottlieb, R. A. (2018) · Journal of Visualized Experiments · doi:10.3791/58079 · Cited by 4 · see citing works

Using iPSC-Based Models to Understand the Signaling and Cellular Phenotypes in Idiopathic Autism and 16p11.2 Derived Neurons

Turkalj, L., Mehta, M., Matteson, P. G., Prem, S., Williams, M., Connacher, R., DiCicco-Bloom, E. M., & Millonig, J. H. (2020) · Advances in neurobiology · doi:10.1007/978-3-030-45493-7_4 · Cited by 3 · see citing works

Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs

Park, Y., Lofton, M., Li, D., & Rašin, M. (2021) · Cells · doi:10.3390/cells10020253 · Cited by 3 · see citing works

The chromatin remodeler CHD3 is highly expressed in mature neurons and regulates genes involved in synaptic development and functionPreprint

den Hoed, J., Wong, M. M. K., Claassen, W. J. J., de Hoyos, L., Lütje, L., Heide, M., Huttner, W. Β., & Fisher, S. E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.29.591720 · Cited by 3 · see citing works

Phosphorylation of Shiftless by casein kinase 1 δ/ε is required for its antiviral activity

Wang, Y., Fu, S., Wang, X., & Gao, G. (2025) · Journal of Virology · doi:10.1128/jvi.01864-25 · Cited by 3 · see citing works

Translational control in cortical development

Cremisi, F., & Vignali, R. (2023) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2022.1087949 · Cited by 1 · see citing works

EXOSC3 G191 Variants Trigger System-Wide Recalibration of RNA Processing Machinery

Wijeratne, H. R. S., Runnebohm, A. M., Barron, M. P., Hampton, A. J., Li, R., Peck Justice, S. A., Lenceski, S. H., Rooney, J. D., Smith-Kinnaman, W. R., Chang, G. S., et al. (2026) · doi:10.64898/2026.01.26.701775 · Cited by 1 · see citing works

HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation

Zhang, J., Huang, X., Tang, Y., Zhong, X., Wang, J., Wei, M., Han, X., Ke, Y., & Ba, X. (2025) · Communications Biology · doi:10.1038/s42003-025-09228-9 · Cited by 1 · see citing works

hY3 RNA binds and inhibits ribosomes and modulates the starvation-induced integrated stress response

Pecoraro, V., Kong, E., Sharma, P., Gonskikh, Y., Żywicki, M., Nagelreiter, F., Schosserer, M., Freiburghaus, K., Nuoffer, J., Grillari, J., et al. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag832 · Cited by 1 · see citing works

Transcriptional and posttranscriptional mechanisms of neuronal migration

Krsnik, Ž., Popovitchenko, T., & Rašin, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814407-7.00022-5 · Cited by 1 · see citing works

Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositionsPreprint

Tran, P. T., Budnik, B., Froberg, J. E., & Macklis, J. D. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.22.629968 · Cited by 1 · see citing works

Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositionsPreprint

Tran, P. T., Budnik, B., Froberg, J. E., & Macklis, J. D. (2025) · eLife · doi:10.7554/elife.107488.1 · Cited by 1 · see citing works

Post-transcriptional Regulatory Mechanisms Controlling Development of Murine Cerebral Cortical Precursors

Amadei, G. (2016) · TSpace (University of Toronto)

Development of Ultra-Low-Input nanoRibo-Seq Enables Quantification of Translational Control, Revealing Broad uORF Translation by Subtype-Specific NeuronsPreprint

Froberg, J. E., Durak, O., & Macklis, J. D. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.05.487068

Pantr2 , a trans-acting lncRNA, modulates the differentiation potential of neural progenitors in vivoPreprint

Augustin, J. J., Takayangi, S., Hoang, T. V., Winer, B. L., Blackshaw, S., & Goff, L. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.07.511381

Decreased expression of ribosomal protein Rpl3 contributes to behavioral deficits caused by Shank3 deficiencyPreprint

Verpelli, C., Giona, F., Beretta, S., Zippo, A. G., Vicidomini, C., Ponzoni, L., Sala, M., Jones, C. K., Conn, P. J., Böckers, T. M., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2812308/v1

The human antigen R as an actionable super-hub within the network of cancer cell persistency and plasticity

Merat, R. (2023) · Translational Oncology · doi:10.1016/j.tranon.2023.101722

Molecular Mechanisms of Inner Ear Development and Disease

Yang, H., Ryu, J., & Shim, S. (2023) · Journal of Experimental & Biomedical Sciences/Biomedical Science Letters · doi:10.15616/bsl.2023.29.3.95

Sex-lethal is recruited to chromatin to promote neuronal tRNA synthesis in males through RNA Polymerase III regulationPreprint

Storer, F., McClure, C. D., Estacio‐Gómez, A., Wong, T. L., Minkley, L. J., & Southall, T. D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.25.650657

Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositionsPreprint

Tran, P. T., Budnik, B., Froberg, J. E., & Macklis, J. D. (2025) · eLife · doi:10.7554/elife.107488

Study of Exon Junction Complex in mouse neural stem cells

Mishra, R. (2016) · doi:10.70675/763ca66az53efz4562zb337z755d833bb64d

Impact d’une carence en vitamines B9 et B12 sur l’épitranscriptome m⁶A et la méthylation des protéines histones

Mosca, P. (2021) · doi:10.70675/361c9466zf1bdz4724zb4fdz740a31f41063

Neuronal protein Sex-lethal modulates tRNA synthesis via the polymerase III subunit Polr3E in male Drosophila neurons

Storer, F., McClure, C. D., Estacio‐Gómez, A., Minkley, L. J., Wong, T. L., Markevych, N., & Southall, T. D. (2026) · PLoS Biology · doi:10.1371/journal.pbio.3003863

Recording proteome dynamics in the late-stage embryo at hour-timescale, spatial, and single-cell resolution with MEMBRYOPreprint

Couce-Iglesias, M., Oliani, E., Kerridge, R., Mutschler, F., Valdes, D. S., Welter, A. S., Lukaszewska‐McGreal, B., Meierhofer, D., Imami, K., Fornasiero, E. F., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.21.753234

Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositionsPreprint

Tran, T. P., Budnik, B., Froberg, J. E., & Macklis, J. D. (2026) · eLife · doi:10.7554/elife.107488.2

Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes

Kraushar, M. L., Viljetić, B., Wijeratne, H. R. S., Thompson, K., Jiao, X., Pike, J. W., Medvedeva, V. P., Groszer, M., Kiledjian, M., Hart, R. P., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0601-15.2015 · Cited by 52 · see citing works

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

Popovitchenko, T., Thompson, K., Viljetić, B., Jiao, X., Kontonyiannis, D. L., Kiledjian, M., Hart, R. P., & Rašin, M. R. (2016) · Scientific Reports · doi:10.1038/srep28998 · Cited by 35 · see citing works

Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons

Zhao, Y., He, X., Song, Z.-F., Guo, Y., Zhang, Y.-N., Yu, H., He, Z., Xiong, W., Guo, W., & Zhu, X.-J. (2020) · Development · doi:10.1242/dev.183509 · Cited by 12 · see citing works

The frontier of RNA metamorphosis and ribosome signature in neocortical development

Kraushar, M. L., Popovitchenko, T., Volk, N. L., & Rašin, M. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.02.003 · Cited by 18 · see citing works

The roles of RNA binding protein Celf4 and ribosomal protein Rpl13a in the development of mammalian neocortex

Salamon, I. (2023) · Rutgers University Community Repository (Rutgers University) · doi:10.7282/t3-rhwt-ej09