MYC on the Path to Cancer

Dang, Chi V.·2012·Cell

Cited by (1,009)

Items 501–600 of 1,009

  1. Sphingosine Kinase 2 Promotes Acute Lymphoblastic Leukemia by Enhancing MYC Expression
    Craig Thomas Wallington-Beddoe, Jason A. Powell, Daochen Tong, Stuart Maxwell Pitson, Kenneth Francis Bradstock, Linda J. Bendall · 2014 · Cancer Research
  2. Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27
    Lucia García-Gutiérrez, Gabriel Bretones, Ester Molina, Ignacio Aréchaga, Catherine E. Symonds, Juan Carlos Acosta, Rosa E. Blanco, Adrián Fernández, Leticia Alonso, Piotr Siciński et al. · 2019 · Scientific Reports
  3. Human MYC G-quadruplex: From discovery to a cancer therapeutic target
    Wenmeng Wang, Shuangli Hu, Yaru Gu, Yunxiao Yan, Daniel B. Stovall, Dangdang Li, Guangchao Sui · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  4. Extracellular Vesicle-Mediated Bilateral Communication between Glioblastoma and Astrocytes
    Lisa Nieland, Liza M. Morsett, Marike L. D. Broekman, Xandra O. Breakefield, Erik R. Abels · 2020 · Trends in Neurosciences
  5. Practical Use of Immortalized Cells in Medicine: Current Advances and Future Perspectives
    Voloshin, Nikita, Tyurin-Kuzmin, Pyotr, Karagyaur, Maxim, Akopyan, Zhanna, Kulebyakin, Konstantin · 2023 · International Journal of Molecular Sciences
  6. Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis
    Marcela Cristina Robaina, Luciano Mazzoccoli, Viviane Oliveira Arruda, Flaviana Ruade de Souza Reis, Alexandre Gustavo Apa, Lídia Maria Magalhães de Rezende, Claudete Esteves Klumb · 2015 · Experimental and Molecular Pathology
  7. The use of small molecules in somatic-cell reprogramming
    Alexander Joel Federation, James E. Bradner, Alexander Meissner · 2013 · Trends in Cell Biology
  8. Preclinical activity of CPI-0610, a novel small-molecule bromodomain and extra-terminal protein inhibitor in the therapy of multiple myeloma
    Ka Tat Siu, Janani Ramachandran, Andrew Jenho Yee, Homare Eda, Loredana Santo, Cristina Panaroni, Jennifer A. Mertz, Robert J. Sims, Michael Robert Cooper, Noopur S Raje · 2016 · Leukemia
  9. The role of CIP2A in cancer: A review and update
    Soofiyani, Saiedeh Razi, Hejazi, Mohammad Saeid, Baradaran, Behzad · 2017 · Biomedicine & Pharmacotherapy
  10. Next-Generation NAMPT Inhibitors Identified by Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens
    Christina Matheny, Michael C. Wei, Michael Cory Bassik, Alicia J. Donnelly, Martin Kampmann, 正幸 岩崎, Obdulio Piloto, David E. Solow-Cordero, Donna M. Bouley, Rachel E. Rau et al. · 2013 · Chemistry & Biology
  11. Lactate Metabolism and Immune Modulation in Breast Cancer: A Focused Review on Triple Negative Breast Tumors
    Adviti Naik, Julie V. Decock · 2020 · Frontiers in Oncology
  12. MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
    Seyeon Bae, Peter Sang Uk Park, Yeji Lee, Se Hwan Mun, Ευγενία Γιαννοπούλου, Takayuki Fujii, Kelvin P. Lee, Sara Nunes Violante, Justin R. Cross, Kyung‐Hyun Park‐Min · 2021 · Cell Reports
  13. Insulin and cancer: a tangled web
    Brooks P. Leitner, Stephan Siebel, Ngozi D. Akingbesote, Xinyi Zhang, Rachel J. Perry · 2022 · Biochemical Journal
  14. Ketogenic diet reshapes cancer metabolism through lysine β-hydroxybutyrylation
    Junhong Qin, Xinhe Huang, Shengsong Gou, Sitao Zhang, Yujie Gou, Qian Zhang, Hongyu Chen, Lin Sun, Miaomiao Chen, Dan Liu et al. · 2024 · Nature Metabolism
  15. MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer
    Sílvia Casacuberta‐Serra, Íñigo González-Larreategui, Daniel Capitán-Leo, Laura Soucek · 2024 · Signal Transduction and Targeted Therapy
  16. Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways
    Okkeun Jung, Jongsung Lee, Yu Jin Lee, Jung‐Mi Yun, Young–Jin Son, Jae Youl Cho, Chongsuk Ryou, Sang Yeol Lee · 2016 · Bioorganic & Medicinal Chemistry Letters
  17. Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis
    Peng Shao, Qi Liu, Peterson Kariuki Maina, Jiayue Cui, Thomas Bair, Tiandao Li, Shaikamjad Umesalma, Weizhou Zhang, Hank Heng Qi · 2016 · Nucleic Acids Research
  18. Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
    Raquel Buj, Katherine M. Aird · 2018 · Frontiers in Endocrinology
  19. Down-Regulation of miR-129-5p Inhibits Growth and Induces Apoptosis in Laryngeal Squamous Cell Carcinoma by Targeting APC
    Minghua Li, Linli Tian, Lin Wang, Hongchao Yao, JiaRui Zhang, Jianguang Lu, Yanan Sun, Xu Gao, Hui Xiao, Ming Liu · 2013 · PLoS ONE
  20. Colorectal cancer prevention: Immune modulation taking the stage
    Rochelle Fletcher, Yi‐Jun Wang, Robert E. Schoen, Olivera J. Finn, Jian Yu, Lin Zhang · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  21. Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy
    Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Matilda Ilander, Henna H.E. Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Björn von Eyß et al. · 2019 · Nature Communications
  22. Molecular pathogenesis of germinal center‐derived B cell lymphomas
    Laura Pasqualucci · 2019 · Immunological Reviews
  23. Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL
    Ting Yu, Lingyu Ran, Hongwen Zhao, Pin Yin, Wei Li, Jie Lin, Hui Mao, Dongping Cai, Qiang Ma, Xiaojuan Pan et al. · 2021 · Molecular Therapy — Nucleic Acids
  24. Pancreatic Neuroendocrine Tumors: Molecular Mechanisms and Therapeutic Targets
    Chandra Kumar Maharjan, Po Hien Ear, Catherine G. Tran, James R. Howe, Chandrikha Chandrasekharan, Dawn E. Quelle · 2021 · Cancers
  25. MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma
    Jie Xiong, L Wang, X-C Fei, X-F Jiang, Zhong Zheng, Yiming Zhao, CF Wang, Biao Li, S-J Chen, Anne Janin et al. · 2017 · Blood Cancer Journal
  26. Targeted Disruption of Myc–Max Oncoprotein Complex by a Small Molecule
    Seung Hyuk Choi, Madhupriya Mahankali, Sang Jun Lee, Mitchell V. Hull, H. Michael Petrassi, Arnab K. Chatterjee, Peter G. Schultz, Katherine A. Jones, Weijun Shen · 2017 · ACS Chemical Biology
  27. Targeting RNA polymerase I to treat MYC-driven cancer
    Gretchen Poortinga, Leonie M. Quinn, Ross D. Hannan · 2014 · Oncogene
  28. Autoantibodies against tumor-associated antigens in the early detection of lung cancer
    Liping Dai, Jun-Chieh James Tsay, Jitian Li, Ting-An Yie, John S. Munger, Harvey Ira Pass, William N. Rom, Yi Zhang, Eng M. Tan, Jian-Ying Zhang · 2016 · Lung Cancer
  29. Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia
    Deborah Bongiovanni, Valentina Saccomani, Erich Piovan · 2017 · International Journal of Molecular Sciences
  30. New Insights into the Interplay between Non-Coding RNAs and RNA-Binding Protein HnRNPK in Regulating Cellular Functions
    Yongjie Xu, Wei Wu, Han Qiu, Yaling Wang, Cencen Li, Pengpeng Zhang, Haixia Xu · 2019 · Cells
  31. Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer
    Fang Huang, Kenneth E. Huffman, Zixi Wang, Xun Wang, Kailong Li, Feng Cai, Chendong Yang, Ling Cai, T. Shane Shih, Lauren G. Zacharias et al. · 2020 · Journal of Clinical Investigation
  32. Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer
    Ayushi S. Patel, Seungyeul Yoo, Ranran Kong, Takashi Sato, Abhilasha Sinha, Sarah Karam, Li Bao, Maya Fridrikh, Katsura Emoto, German Nudelman et al. · 2021 · Science Advances
  33. Calcium signaling orchestrates glioblastoma development: Facts and conjunctures
    Catherine Leclerc, Jacques Haiech, Francisco Javier Aulestia, Marie‐Claude Kilhoffer, Andrew L. Miller, Isabelle Néant, Sarah Webb, Étienne Schaeffer, Marie‐Pierre Junier, Hervé Chneiweiss et al. · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  34. The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism
    Said Izreig, Bożena Samborska, Radia Marie Johnson, Alexey Sergushichev, Eric H. Ma, Carine R. Lussier, Ekaterina Loginicheva, Ariel O. Donayo, Maya C. Poffenberger, Selena M. Sagan et al. · 2016 · Cell Reports
  35. MYC‐driven inhibition of the glutamate‐cysteine ligase promotes glutathione depletion in liver cancer
    Brittany N. Anderton, Roman Camarda, Sanjeev Balakrishnan, Asha Balakrishnan, Rebecca A. Kohnz, Lionel Lim, Kimberley Jane Evason, Olga Momčilović, Klaus Kruttwig, Qiang Huang et al. · 2017 · EMBO Reports
  36. c-Myc promotes renal fibrosis by inducing integrin αv-mediated transforming growth factor-β signaling
    Yang Shen, Naijun Miao, Bao Wang, Jinlan Xu, Xinxin Gan, Dan Xu, Li Zhou, Hong Xue, Wei Zhang, Li Yang et al. · 2017 · Kidney International
  37. Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway
    Jie Pan, Jiaying Shen, Wengong Si, Chengyong Du, Danni Chen, Liang Xu, Minya Yao, Peifen Fu, Weimin Fan · 2017 · Oncotarget
  38. Unravel the molecular mechanism of XBP1 in regulating the biology of cancer cells
    Weimei Shi, Zhixi Chen, Linfu Li, Hai Liu, Rui Zhang, Qilai Cheng, Daohua Xu, Longhuo Wu · 2019 · Journal of Cancer
  39. Extracellular vesicle PD‐L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
    Liu, Jiaxing, Peng, Xueqiang, Yang, Shuo, Li, Xinyu, Huang, Mingyao, Wei, Shibo, Zhang, Sheng, He, Guangpeng, Zheng, Hongyu, Fan, Qing et al. · 2022 · Cell Communication and Signaling
  40. Discovery of WD Repeat-Containing Protein 5 (WDR5)–MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design
    Chacón Simon, Selena, Wang, Feng, Thomas, Lance R., Phan, Jason, Zhao, Bin, Olejniczak, Edward T., Macdonald, Jonathan D., Shaw, J. Grace, Schlund, Caden, Payne, William et al. · 2020 · Journal of Medicinal Chemistry
  41. Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma
    Allison Rose Hanaford, Jesse Alt, Rana Rais, Sabrina Z. Wang, Harpreet Kaur, Daniel L.J. Thorek, Charles G. Eberhart, Barbara Stauch Slusher, Allison M. Martin, Eric H. Raabe · 2019 · Translational Oncology
  42. Medulloblastoma genomics in the modern molecular era
    Rahul Kumar, Anthony P. Y. Liu, Paul A. Northcott · 2019 · Brain Pathology
  43. Crosstalk of MicroRNAs and Oxidative Stress in the Pathogenesis of Cancer
    Can Lu, Danting Zhou, Qiang Wang, Wenliang Liu, Fenglei Yu, Fang Wu, Chen Chen · 2020 · Oxidative Medicine and Cellular Longevity
  44. Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis
    Mohd Farhan, Marta Silva, Xingan Xing, Yü Huang, Wenhua Zheng · 2020 · Cells
  45. USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-Myc
    Jianchao Ge, Wandong Yu, Junhong Li, Hangbin Ma, Pengyu Wang, Yinghao Zhou, Yang Wang, Jun Zhang, Guowei Shi · 2021 · Journal of Experimental & Clinical Cancer Research
  46. Current Status and Prospects of Targeted Therapy for Osteosarcoma
    Zunguo Hu, Shuang Wen, Zijun Huo, Qing Wang, Jiantao Zhao, Zihao Wang, Yanchun Chen, Lingyun Zhang, Fenghua Zhou, Zhangyu Guo et al. · 2022 · Cells
  47. Mitochondrial Citrate Transporter-dependent Metabolic Signature in the 22q11.2 Deletion Syndrome
    Eleonora Napoli, Flora Tassone, Sarah Wong, Kathleen Angkustsiri, Tony J. Simon, Gyu‐Yong Song, Cecilia Giulivi · 2015 · Journal of Biological Chemistry
  48. Msn2/4 regulate expression of glycolytic enzymes and control transition from quiescence to growth
    Zheng Kuang, Sudarshan Pinglay, Hongkai Ji, Jef D. Boeke · 2017 · eLife
  49. mTOR complex 1 controls the nuclear localization and function of glycogen synthase kinase 3β
    Stephen James Bautista, Ivan Boras, Adriano Vissa, Noa Mecica, Christopher M. Yip, Peter Kijun Kim, Costin N. Antonescu · 2018 · Journal of Biological Chemistry
  50. The role of circadian clock genes in tumors
    Han-Xue Li · 2019 · OncoTargets and Therapy
  51. MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity
    Renumathy Dhanasekaran, Virginie Baylot, Minsoon Kim, Sibu P. Kuruvilla, David I. Bellovin, Nia Adeniji, Anand Rajan, Ian K. Lai, Meital Gabay, Ling Tong et al. · 2020 · eLife
  52. The cancer-promoting gene fatty acid-binding protein 5 (FABP5) is epigenetically regulated during human prostate carcinogenesis
    Koichiro Kawaguchi, Ayumi Kinameri, Shunsuke Suzuki, Shogo Senga, Youqiang Ke, Hiroshi Fujii · 2015 · Biochemical Journal
  53. Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer
    Devon R. Blake, Angelina V. Vaseva, Richard G. Hodge, McKenzie P. Kline, Thomas S.K. Gilbert, Vikas Tyagi, Daowei Huang, Gabrielle C. Whiten, Jacob E. Larson, Xiaodong Wang et al. · 2019 · Science Signaling
  54. Enhancer RNA: What we know and what we can achieve
    Zhenzhen Han, Wei Li · 2022 · Cell Proliferation
  55. c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses
    Xuyan Wang, Yuan Wei, Bo Hu, Yuan Liao, Wen‐Hua Wan, Wen‐Hua Wan, Chun-Xiang Huang, Mahepali Mahabati, Zhengyu Liu, Jing-Rui Qu et al. · 2022 · Signal Transduction and Targeted Therapy
  56. MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
    Benjamin A. H. Smith, Anja Deutzmann, Kristina M. Correa, Corleone S. Delaveris, Renumathy Dhanasekaran, Christopher G. Dove, Delaney K. Sullivan, Simon Wisnovsky, Jessica C. Stark, John V. Pluvinage et al. · 2023 · Proceedings of the National Academy of Sciences
  57. Prognostic role of Oct4, CD44 and c-Myc in radio–chemo-resistant oral cancer patients and their tumourigenic potential in immunodeficient mice
    Sharada Sawant, Ravindran Caspa Gokulan, Harsh Dongre, Milind M. Vaidya, Devendra Arvind Chaukar, Kumar Prabhash, Arvind Ingle, Shriya Joshi, Prerana P. Dange, Shreyas Joshi et al. · 2015 · Clinical Oral Investigations
  58. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth
    Michael S. Nakazawa, T.S. Karin Eisinger‐Mathason, Navid Sadri, Joshua D. Ochocki, Terence P.F. Gade, Ruchi Kaushik Amin, Marie Celeste Simon · 2016 · Nature Communications
  59. The Novel Long Noncoding RNA linc00467 Promotes Cell Survival but Is Down-Regulated by N-Myc
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  60. Genetic Hitchhiking and Population Bottlenecks Contribute to Prostate Cancer Disparities in Men of African Descent
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  61. Transcription Factors That Govern Development and Disease: An Achilles Heel in Cancer
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  62. Current strategies and progress for targeting the “undruggable” transcription factors
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  64. Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung cancer
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  65. Glycolytic metabolism influences global chromatin structure
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  66. Redeployment of Myc and E2f1–3 drives Rb-deficient cell cycles
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  67. Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts
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  68. RNA Polymerase I Inhibition with CX‐5461 as a Novel Therapeutic Strategy to Target MYC in Multiple Myeloma
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  69. The MYC mRNA 3′‐UTR couples RNA polymerase II function to glutamine and ribonucleotide levels
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  70. Iron chelators in cancer therapy
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  71. Targeting c-Myc to Overcome Acquired Resistance of EGFR Mutant NSCLC Cells to the Third-Generation EGFR Tyrosine Kinase Inhibitor, Osimertinib
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  72. Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer
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  73. Targeting the Wnt/β-catenin pathway in human osteosarcoma cells
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  74. Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis
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  75. Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters
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  78. Ribosome Biogenesis Alterations in Colorectal Cancer
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  79. Drugging the “Undruggable” MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers
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  80. MYC-driven aggressive B-cell lymphomas: biology, entity, differential diagnosis and clinical management
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  81. Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes
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  82. Divergent viral presentation among human tumors and adjacent normal tissues
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  83. NMR Structure of a Triangulenium‐Based Long‐Lived Fluorescence Probe Bound to a G‐Quadruplex
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  84. Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities
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  85. The magic bullet: Niclosamide
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  86. Advances in the interaction of glycolytic reprogramming with lactylation
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  87. Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project
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  88. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations
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  89. Differential gene expression patterns between smokers and non‐smokers: cause or consequence?
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  90. Targeting bromodomain-containing protein 4 (BRD4) inhibits MYC expression in colorectal cancer cells
    Christoph Otto, Stefanie Schmidt, C. Kastner, Sarah Denk, J. Kettler, N. Müller, Christoph‐Thomas Germer, Elmar Wolf, Peter Gallant, Armin Wiegering · 2019 · Neoplasia
  91. Dissecting transcriptional amplification by MYC
    Zuqin Nie, Chunhua Guo, Subhendu Das, Carson C. Chow, Eric Batchelor, S. Stoney Simons, David Levens · 2020 · eLife
  92. Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma
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  93. The Genetics and Mechanisms of T-Cell Acute Lymphoblastic Leukemia
    Francesca Gianni, Laura Belver, Adolfo A. Ferrando · 2019 · Cold Spring Harbor Perspectives in Medicine
  94. MMP‑1 is overexpressed in triple‑negative breast cancer tissues and the knockdown of MMP‑1 expression inhibits tumor cell malignant behaviors in�vitro
    Qi‐Min Wang, Li Lv, Ying Tang, Li Zhang, Li‑Fen Wang · 2018 · Oncology Letters
  95. Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers
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  96. Control of cell metabolism by the epidermal growth factor receptor
    Laura A. Orofiamma, Dafne Vural, Costin N. Antonescu · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  97. PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer
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  98. Menin enhances c-Myc-mediated transcription to promote cancer progression
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  99. The Role Played by Wnt/β-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia
    Francesca Chiarini, Francesca Paganelli, Alberto Maria Martelli, Camilla Evangelisti · 2020 · International Journal of Molecular Sciences
  100. STAT3 is a master regulator of epithelial identity and KRAS-driven tumorigenesis
    Stephen D’Amico, Jiaqi Shi, Benjamin L. Martin, Howard C. Crawford, Oleksi Petrenko, Nancy C. Reich · 2018 · Genes & Development