MYC on the Path to Cancer

Dang, Chi V.·2012·Cell

Cited by (1,008)

Items 801–900 of 1,008

  1. Bufalin inhibits pancreatic cancer by inducing cell cycle arrest via the c-Myc/NF-κB pathway
    Xia Liu, Xiangyang Xiao, Qiyang Shou, Junfeng Yan, Long Chen, Huiying Fu, Jianchao Wang · 2016 · Journal of Ethnopharmacology
  2. JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma
    Limei Wang, Xiuyin Wu, Ping Cheong Huang, Zhijun Lv, Yuping Qi, Xiujuan Wei, Pishan Yang, Fenghe Zhang · 2016 · Oncology Reports
  3. The Diverse Consequences of FOXC1 Deregulation in Cancer
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  4. NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer
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  5. Argonaute binding within 3′-untranslated regions poorly predicts gene repression
    Yongjun Chu, Audrius Kilikevičius, Jing Liu, Krystal C. Johnson, Shinnichi Yokota, David R. Corey · 2020 · Nucleic Acids Research
  6. Turning Up the Heat on MYC: Progress in Small-Molecule Inhibitors
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  7. Malignancy and IFITM3: Friend or Foe?
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  8. Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia
    Xueliang Gao, Shenghui Qin, Yongxia Wu, Chen Chu, Baishan Jiang, Roger H. Johnson, Dong Kuang, Jie Zhang, Xi Wang, Anand S. Mehta et al. · 2021 · Journal of Clinical Investigation
  9. Ribosome 18S m6A methyltransferase METTL5 promotes pancreatic cancer progression by modulating c‑Myc translation
    Hua Huang, Huan Li, Ruining Pan, Sijia Wang, Aamir Ali Khan, Yue Zhao, Huiyu Zhu, Xinhui Liu · 2021 · International Journal of Oncology
  10. Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc
    Yunhua Peng, Jing Liu, Zhen Wang, Chun‐Ping Cui, Shuangxi Zhang, Shuangxi Zhang, Peipei Gao, Zhanwu Hou, Huadong Liu, Jianping Guo et al. · 2022 · Cell Death and Differentiation
  11. MYC is a critical target of FBXW7
    Mai Sato, Ruth Rodriguez Barrueco, Jiyang Yu, Catherine Do, José M. Silva, Jean Gautier · 2014 · Oncotarget
  12. Generation of Osteosarcomas from a Combination of Rb Silencing and c-Myc Overexpression in Human Mesenchymal Stem Cells
    Jir‐You Wang, Po‐Kuei Wu, Paul Chih-Hsueh Chen, Chia-Wen Lee, Wei‐Ming Chen, Shih‐Chieh Hung · 2016 · Stem Cells Translational Medicine
  13. Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin
    Armin Wiegering, Niels Matthes, Bettina Mühling, Monika Koospal, Anne Quenzer, Stephanie Peter, Christoph-Thomas Germer, Michael Linnebacher, Christoph Otto · 2017 · Neoplasia
  14. E-Cadherin/β-Catenin Complex: A Target for Anticancer and Antimetastasis Plants/Plant-derived Compounds
    Majid Tafrihi, Roohollah Nakhaei Sistani · 2017 · Nutrition and Cancer
  15. Hepatitis B Virus-Associated Hepatocellular Carcinoma and Hepatic Cancer Stem Cells
    Saravana Kumar Kailasam Mani, OURANIA M. ANDRISANI · 2018 · Genes
  16. MYC-induced metabolic stress and tumorigenesis
    Adam J. Wolpaw, Chi Van Dang · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  17. BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition
    Sa Rang Kim, Julia M. Lewis, Benoit M. Cyrenne, Patrick F. Monico, Fatima Nadeem Mirza, Kacie R. Carlson, Francine M. Foss, Michael Girardi · 2018 · Oncotarget
  18. It takes a team: a gain-of-function story of p53-R249S
    Huai Wang, Peng Liao, Shelya X. Zeng, Hua Lu · 2019 · Journal of Molecular Cell Biology
  19. CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer
    Houliang Deng, Xiaowen Guan, Longcai Gong, Jianming Zeng, Hongjie Zhang, Mike Y. Chen, Gang Li · 2019 · Scientific Reports
  20. MiR-644a Disrupts Oncogenic Transformation and Warburg Effect by Direct Modulation of Multiple Genes of Tumor-Promoting Pathways
    Jey Sabith Ebron, Eswar Shankar, Jagjit Singh, Kavleen Sikand, Crystal M. Weyman, Sanjay Gupta, Daniel J. Lindner, Xiaoqi Liu, Moray J. Campbell, Girish C. Shukla · 2019 · Cancer Research
  21. Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation
    Marion Le Grand, Anna Mukha, Jakob Püschel, Emanuele Valli, Alvin Kamili, Orazio Vittorio, Anna Dubrovska, Maria Kavallaris · 2020 · Theranostics
  22. TFEB Links MYC Signaling to Epigenetic Control of Myeloid Differentiation and Acute Myeloid Leukemia
    Seongseok Yun, Nicole D. Vincelette, Xiaoqing Yu, Gregory W. Watson, Mario R. Fernandez, Chunying Yang, Taro Hitosugi, Chia‐Ho Cheng, Audrey R. Freischel, Ling Zhang et al. · 2020 · Blood Cancer Discovery
  23. Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy
    Xiao‐Xin Sun, Yanping Li, Rosalie C. Sears, Mu‐Shui Dai · 2021 · Frontiers in Oncology
  24. Phase separation in Cancer: From the Impacts and Mechanisms to Treatment potentials
    Peng Qiu, Shiming Tan, Longzheng Xia, Nayiyuan Wu, Linda Oyang, Yanyan Tang, Min Su, Xia Luo, Ying Wang, Xiaowu Sheng et al. · 2022 · International Journal of Biological Sciences
  25. An Integrative Human Pan-Cancer Analysis of Cyclin-Dependent Kinase 1 (CDK1)
    Xuanyou Liu, Hao Wu, Zhenguo Liu · 2022 · Cancers
  26. Myc suppresses tumor invasion and cell migration by inhibiting JNK signaling
    Xianjue Ma, Jing-Yi Huang, Y Tian, Yiliang Chen, Yinke Yang, Xiao Zhang, Fan Zhang, Lei Xue · 2017 · Oncogene
  27. BC200 (BCYRN1) – The shortest, long, non-coding RNA associated with cancer
    J. Samson, Sarah Cronin, Kellie A. Dean · 2018 · Non-coding RNA Research
  28. Combination therapy with protein kinase inhibitor H89 and Tetrandrine elicits enhanced synergistic antitumor efficacy
    Man Yu, Ting Liu, Yi-Cheng Chen, Yafang Li, Wenhua Li · 2018 · Journal of Experimental & Clinical Cancer Research
  29. Intricate crosstalk between MYC and non‐coding RNA s regulates hallmarks of cancer
    Lotteke J. Y. M. Swier, Agnieszka Dzikiewicz‐Krawczyk, Melanie Winkle, Anke van den Berg, Joost L. Kluiver · 2018 · Molecular Oncology
  30. Metabolic reprogramming in the pathogenesis of glioma: Update
    Kenta Masui, Hiromi Onizuka, Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata · 2019 · Neuropathology
  31. Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation
    Jeannine Diesch, Megan J. Bywater, Elaine Sanij, Donald P. Cameron, William S. Schierding, Natalie Brajanovski, Jinbae Son, Jirawas Sornkom, Nadine Hein, M. Evers et al. · 2019 · Communications Biology
  32. c-Myc regulates the CDK1/cyclin B1 dependent‑G2/M cell cycle progression by histone H4 acetylation in Raji cells
    Yan Yang, Kai Xue, Zhi Li, Zheng Wei, Weijie Dong, Jiazhe Song, Shijie Sun, Tonghui Ma, Wenzhe Li · 2018 · International Journal of Molecular Medicine
  33. Nanodiamond-Mediated Delivery of a G9a Inhibitor for Hepatocellular Carcinoma Therapy
    Mengjie Gu, Tan Boon Toh, Lissa Hooi, Jhin Jieh Lim, Xiyun Zhang, Edward Kai‐Hua Chow · 2019 · ACS Applied Materials & Interfaces
  34. Long noncoding RNA CMPK2 promotes colorectal cancer progression by activating the FUBP3–c-Myc axis
    Qingzu Gao, Rui Zhou, Yuan Meng, Rongfei Duan, Ling Wu, Rui Li, Fengliu Deng, Chuang Lin, Liang Zhao · 2020 · Oncogene
  35. Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer
    Dominik Andreas Barth, Felix Prinz, Julia Teppan, Katharina Jonas, Christiane Klec, Martin Pichler · 2020 · Non-Coding RNA
  36. Recent advancements in PARP inhibitors-based targeted cancer therapy
    Ping Zhou, Justin L. Wang, Daniel Mishail, Cun‐Yu Wang · 2020 · Precision Clinical Medicine
  37. OCTAD: an open workspace for virtually screening therapeutics targeting precise cancer patient groups using gene expression features
    Zeng, Billy, Glicksberg, Benjamin S., Newbury, Patrick, Chekalin, Evgeny, Xing, Jing, Liu, Ke, Wen, Anita, Chow, Caven, Chen, Bin · 2021 · Nature Protocols
  38. Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3
    Xuejiao Leng, Jianfeng Wang, Na An, Xue Wang, Yile Sun, Zhiwei Chen · 2020 · Oncogene
  39. Tilting MYC toward cancer cell death
    Colleen T. Harrington, Elena Sotillo, Chi Van Dang, Andrei Thomas‐Tikhonenko · 2021 · Trends in cancer
  40. New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC
    Wenli Cheng, Min Li, Luyun Zhang, Cheng Zhou, Susu Yu, Xinyue Peng, Wenji Zhang, Wenjuan Zhang · 2022 · Frontiers in Pharmacology
  41. ERK and c-Myc signaling in host-derived tumor endothelial cells is essential for solid tumor growth
    Zehua Zuo, Jie Liu, Zhihao Sun, Yu‐Wei Cheng, Michael Ewing, Thomas Henrik Bugge, Toren Finkel, Stephen Howard Leppla, Shihui Liu · 2022 · Proceedings of the National Academy of Sciences
  42. Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages
    Luke A. Bourner, Linda A. Chung, Haiyan Long, Anne F. McGettrick, Junpeng Xiao, Kenneth D. W. Roth, Jade D. Bailey, Marie Strickland, Bo Tan, Jason Cunningham et al. · 2024 · Cell Reports
  43. Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening
    Zongxiang Zhou, Manishha Patel, Nicholas Ng, Mindy H. Hsieh, Anthony P. Orth, John R. Walker, Serge Batalov, Jennifer L Harris, Jun Liu · 2014 · BMC Cancer
  44. Targeting the MYC and PI3K Pathways Eliminates Leukemia-Initiating Cells in T-cell Acute Lymphoblastic Leukemia
    Suzanne Schubbert, Anjelica M. Cardenas, Harrison Chen, Consuelo Garcia, Wei Guo, James E. Bradner, Hong Wu · 2014 · Cancer Research
  45. Histone deacetylase inhibitor prevents cell growth in Burkitt’s lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101
    Ana Carolina dos Santos Ferreira, Marcela Cristina Robaina, Lídia Maria Magalhães de Rezende, Patrícia Severino, Claudete Esteves Klumb · 2014 · Annals of Hematology
  46. Cyclophilin B Supports Myc and Mutant p53-Dependent Survival of Glioblastoma Multiforme Cells
    Jae Won Choi, Mark A. Schroeder, Jann Nagina Sarkaria, Richard J. Bram · 2013 · Cancer Research
  47. Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature
    Alejandro Vázquez‐Martín, Olga V. Anatskaya, Alessandro Giuliani, Jekaterina A. Erenpreisa, Sui Huang, Kristīne Salmiņa, Inna Inashkina, Anda Huna, Nikolay N. Nikolsky, Alexander E. Vinogradov · 2016 · Oncotarget
  48. STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence
    Benjamin L. Bryson, Damian J. Junk, Rocky Cipriano, Mark W. Jackson · 2016 · Cell Cycle
  49. N-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc
    Yongfang Wang, You Zhou, Feng Tao, Shoujie Chai, Xia Xu, Ying Yang, Yiming Yang, Haiyan Xu, Kai Wang · 2017 · Cancer Letters
  50. Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion
    Yukiko Takeuchi, Yasumune Nakayama, Eiichiro Fukusaki, Yasuhiro Irino · 2017 · Biochemical and Biophysical Research Communications
  51. PLK1 Inhibition Targets Myc-Activated Malignant Glioma Cells Irrespective of Mismatch Repair Deficiency–Mediated Acquired Resistance to Temozolomide
    Fumi Higuchi, Alexandria L. Fink, Juri Kiyokawa, Julie J. Miller, Mara V.A. Koerner, Daniel P. Cahill, Hiroaki Wakimoto · 2018 · Molecular Cancer Therapeutics
  52. c-Myc induced upregulation of long non-coding RNA SNHG16 enhances progression and carcinogenesis in oral squamous cell carcinoma
    Shangfeng Li, Shengkai Zhang, Jie Chen · 2019 · Cancer Gene Therapy
  53. A Regulator of Metabolic Reprogramming: MicroRNA Let-7
    Shuai Jiang · 2019 · Translational Oncology
  54. RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers
    Jiwei Zhang, Shengli Li, Ling Zhang, Juan Xu, Mingxu Song, Tingting Shao, Zhaohui Huang, Yongsheng Li · 2020 · Molecular Therapy
  55. Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice
    Yue Sheng, Rui Ma, Chunjie Yu, Qiong Wu, Steven Zhang, Kimberly Paulsen, Jiwang Zhang, Hongyu Ni, Yong Huang, Yi Zheng et al. · 2020 · Blood
  56. Bladder Tumor Subtype Commitment Occurs in Carcinoma In Situ Driven by Key Signaling Pathways Including ECM Remodeling
    Adrian Wullweber, Reiner Strick, Fabienne Lange, Danijel Sikic, Helge W. Taubert, Sven Wach, Bernd Wullich, Simone Bertz, Veronika Weyerer, Robert Stoehr et al. · 2021 · Cancer Research
  57. Control of Vertebrate Development by MYC
    Peter J. Hurlin · 2013 · Cold Spring Harbor Perspectives in Medicine
  58. Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway
    Lan, Yulong, Lou, Jiacheng, Hu, Jiliang, Yu, Zhikuan, Lyu, Wen, Zhang, Bo · 2020 · Cancer Biology and Medicine
  59. Insights into Aflatoxin B1 Toxicity in Cattle: An In Vitro Whole-Transcriptomic Approach
    Marianna Pauletto, Roberta Tolosi, Mery Giantin, Giorgia Guerra, Andrea Barbarossa, Anna Zaghini, Mauro Dacasto · 2020 · Toxins
  60. MYCN and Metabolic Reprogramming in Neuroblastoma
    Mohit Bansal, Anamika Gupta, Han‐Fei Ding · 2022 · Cancers
  61. Therapeutic Targeting of MYC in Head and Neck Squamous Cell Carcinoma
    Shuo Liu, Zhen Qin, Yaqing Mao, Wenbo Zhang, Yujia Wang, Lingfei Jia, Xin Peng · 2022 · OncoImmunology
  62. Vitamin D in Cancer Prevention: Gaps in Current Knowledge and Room for Hope
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  63. G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures
    Andreas Berner, Rabindra Nath Das, Naresh Bhuma, Justyna Golebiewska, Alva Abrahamsson, Måns Andréasson, Namrata Chaudhari, Mara Doimo, Partha Pratim Bose, Karam Chand et al. · 2024 · Journal of the American Chemical Society
  64. Dual-role transcription factors stabilize intermediate expression levels
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  65. Antitumor mechanisms when pRb and p53 are genetically inactivated
    Liang Zhu, Zhonglei Lu, Heng-tai Zhao · 2014 · Oncogene
  66. Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells
    Xingyao Li, Jian‐Xin Pu, Shi‐You Jiang, Jia Su, Lingmei Kong, Bingyu Mao, Han‐Dong Sun, Yan Li · 2013 · PLoS ONE
  67. The enforced expression of c-Myc in pig fibroblasts triggers mesenchymal-epithelial transition (MET) via F-actin reorganization and RhoA/Rock pathway inactivation
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  68. MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group
    Risa Niemas-Teshiba, Ryosuke Matsuno, Larry L. Wang, Xao X. Tang, Bill Chiu, Jasmine C. Zeki, Jeannine M. Coburn, Kimberly J. Ornell, Arlene H. Naranjo, Collin Van Ryn et al. · 2017 · Oncotarget
  69. The c‐MYC–BMI1 axis is essential for SETDB1‐mediated breast tumourigenesis
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  70. Chronic Hexavalent Chromium Exposure Induces Cancer Stem Cell-Like Property and Tumorigenesis by Increasing c-Myc Expression
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  71. Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes
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  72. Circular RNA circ-LRP6 facilitates Myc-driven tumorigenesis in esophageal squamous cell cancer
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  73. The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity
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  74. Cellular MYCro Economics: Balancing MYC Function with MYC Expression
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  76. Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis
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  77. High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer
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  79. Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8
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  80. NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling
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  81. Hyaluronic acid enhances proliferation of human amniotic mesenchymal stem cells through activation of Wnt/β-catenin signaling pathway
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  82. FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis
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  83. JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer
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  84. Cell cycle-coupled expansion of AR activity promotes cancer progression
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  85. Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells
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  86. TIMELESS contributes to the progression of breast cancer through activation of MYC
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  87. Aberrant Wnt signaling: a special focus in CNS diseases
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  88. Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction
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  89. MiR-29 silencing modulates the expression of target genes related to proliferation, apoptosis and methylation in Burkitt lymphoma cells
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  90. Targeting FBPase is an emerging novel approach for cancer therapy
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  91. Human UTP14a promotes colorectal cancer progression by forming a positive regulation loop with c-Myc
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  92. Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status
    Davood Bashash, Mohammad Sayyadi, Ava Safaroghli‐Azar, Negar Sheikh‐Zeineddini, Niknam Riyahi, Majid Momeny · 2019 · The International Journal of Biochemistry & Cell Biology
  93. PRMT7 promotes the growth of renal cell carcinoma through modulating the β-catenin/C-MYC axis
    Fei Liu, Lisong Wan, Haibin Zou, Zhengyue Pan, Wanming Zhou, Xiongbing Lu · 2020 · The International Journal of Biochemistry & Cell Biology
  94. Saturated Oxo Fatty Acids (SOFAs): A Previously Unrecognized Class of Endogenous Bioactive Lipids Exhibiting a Cell Growth Inhibitory Activity
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  95. High-throughput screening of salivary polyamine markers for discrimination of colorectal cancer by multisegment injection capillary electrophoresis tandem mass spectrometry
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  96. Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis
    Yiwu Yan, Bo O. Zhou, Qian Chen, Alex Vasquez, Mohini Kamra, Avradip Chatterjee, Yeon‐Joo Lee, Xiaopu Yuan, Leigh Ellis, Dolores Di Vizio et al. · 2022 · Nature Communications
  97. Targeting key proteins involved in transcriptional regulation for cancer therapy: Current strategies and future prospective
    Haixiang Pei, Weikai Guo, Yangrui Peng, Hai Xiong, Yihua Chen · 2022 · Medicinal Research Reviews
  98. Co-occurrence of MYC amplification and TP53 mutations in human cancer
    Peter Ulz, Ellen Heitzer, Michael R. Speicher · 2016 · Nature Genetics
  99. Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium
    Ito, Fumiya, Yanatori, Izumi, Maeda, Yuki, Nimura, Kenta, Ito, Satoki, Hirayama, Tasuku, Nagasawa, Hideko, Kohyama, Norihiko, Okazaki, Yasumasa, Akatsuka, Shinya et al. · 2020 · Redox Biology
  100. c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer
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