MYC on the Path to Cancer

Dang, Chi V.·2012·Cell

Cited by (1,009)

Items 601–700 of 1,009

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  2. A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies
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  3. c-Myc enhances colon cancer cell-mediated angiogenesis through the regulation of HIF-1α
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  4. MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells
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  7. Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc
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  8. SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability
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  9. Epigenetic Repression of STING by MYC Promotes Immune Evasion and Resistance to Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
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  12. A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteins
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  14. Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response
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  16. Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals
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  17. LncRNA THOR acts as a retinoblastoma promoter through enhancing the combination of c-myc mRNA and IGF2BP1 protein
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  18. Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis
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  21. Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells
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  22. A polymorphic MYC response element in KBTBD11 influences colorectal cancer risk, especially in interaction with an MYC-regulated SNP rs6983267
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  23. Targeting MYC Proteins for Tumor Therapy
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  25. MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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  26. Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
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  27. The effects of MYC on tumor immunity and immunotherapy
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  28. Genomic Profiling of Human Penile Carcinoma Predicts Worse Prognosis and Survival
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  29. Inactivation of MYC reverses tumorigenesis
    Ye Li, Stephanie C. Casey, Dean W. Felsher · 2014 · Journal of Internal Medicine
  30. Metabolic changes in cancer cells upon suppression of MYC
    Elena Ansó, Andrew R. Mullen, Dean W. Felsher, José Manuel Matés, Ralph J. DeBerardinis, Navdeep S. Chandel · 2013 · Cancer & Metabolism
  31. Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer
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  32. MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
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  33. Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene
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  34. TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation
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  35. Molecular Mechanisms of MYCN Dysregulation in Cancers
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  36. MYC Cofactors: Molecular Switches Controlling Diverse Biological Outcomes
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  37. Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer
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  38. Biomarkers of Cancer Stem Cells for Experimental Research and Clinical Application
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  44. A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression
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  45. GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway
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  46. Emetine inhibits migration and invasion of human non-small-cell lung cancer cells via regulation of ERK and p38 signaling pathways
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  47. β-catenin regulatesc-MycandCDKN1Aexpression in breast cancer cells
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  48. The enzymes of human diphosphoinositol polyphosphate metabolism
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  49. Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling
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  50. The role of the ribosome in the regulation of longevity and lifespan extension
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  51. Cellular senescence and protein degradation
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  52. Single Agent and Synergistic Activity of the “First-in-Class” Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma
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  53. Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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  54. N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics
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  55. Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer
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  56. CBX8 Suppresses Tumor Metastasis via Repressing Snail in Esophageal Squamous Cell Carcinoma
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  57. Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm
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  68. Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo
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  75. Mantle Cell Lymphoma With MYC Rearrangement
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  81. Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA
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  82. Cyclin-Dependent Kinase-9 Is a Therapeutic Target in MYC-Expressing Diffuse Large B-Cell Lymphoma
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  83. UHRF1-KAT7-mediated regulation of TUSC3 expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells
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  84. OLR1 Promotes Pancreatic Cancer Metastasis via Increased c-Myc Expression and Transcription of HMGA2
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  85. Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer
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  86. Integrin α1β1 expression is controlled by c-MYC in colorectal cancer cells
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  87. Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma
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  88. Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor
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  93. Heat Shock Protein 90α–Dependent B‐Cell‐2–Associated Transcription Factor 1 Promotes Hepatocellular Carcinoma Proliferation by Regulating MYC Proto‐Oncogene c‐MYC mRNA Stability
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  94. Gene duplication and neofunctionalization: POLR3G and POLR3GL
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  96. MYC leads the way
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  97. Aurora kinase A mediates c‐Myc's oncogenic effects in hepatocellular carcinoma
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  98. Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo
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  99. Using immunomic approach to enhance tumor-associated autoantibody detection in diagnosis of hepatocellular carcinoma
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  100. Conceptual Framework for Cutting the Pancreatic Cancer Fuel Supply
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