Daddy Issues: Paternal Effects on Phenotype

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429

The thrifty phenotype hypothesis

Hales, C. N., & Barker, D. J. (2001) · British Medical Bulletin · doi:10.1093/bmb/60.1.5 · Cited by 2,722

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563

Environmental epigenomics and disease susceptibility

Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2045 · Cited by 2,492

Small silencing RNAs: an expanding universe

Ghildiyal, M., & Zamore, P. D. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2504 · Cited by 2,418

Transposable elements and the epigenetic regulation of the genome

Slotkin, R. K., & Martienssen, R. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2072 · Cited by 2,044

Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution

Jablonka, E., & Raz, G. (2009) · The Quarterly Review of Biology · doi:10.1086/598822 · Cited by 1,701

Epigenetic inheritance at the agouti locus in the mouse

Morgan, H. D., Sutherland, H. G. E., Martin, D. I. K., & Whitelaw, E. (1999) · Nature Genetics · doi:10.1038/15490 · Cited by 1,476

Distinctive chromatin in human sperm packages genes for embryo development

Hammoud, S. S., Nix, D. A., Zhang, H., Purwar, J., Carrell, D. T., & Cairns, B. R. (2009) · Nature · doi:10.1038/nature08162 · Cited by 1,383

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327

Transgenerational epigenetic inheritance: myths and mechanisms

Heard, E., & Martienssen, R. A. (2014) · Cell · doi:10.1016/j.cell.2014.02.045 · Cited by 1,864

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

Chen, Q., Yan, M., Cao, Z., Li, X., Zhang, Y., Shi, J., Feng, G.-H., Peng, H., Zhang, X., Zhang, Y., et al. (2016) · Science · doi:10.1126/science.aad7977 · Cited by 1,470

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

Sharma, U., Conine, C. C., Shea, J. M., Boskovic, A., Derr, A. G., Bing, X. Y., Belleannee, C., Kucukural, A., Serra, R. W., Sun, F., et al. (2016) · Science · doi:10.1126/science.aad6780 · Cited by 1,275

Promoting Health and Longevity through Diet: From Model Organisms to Humans

Fontana, L., & Partridge, L. (2015) · Cell · doi:10.1016/j.cell.2015.02.020 · Cited by 1,245

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

Rodgers, A. B., Morgan, C. P., Bronson, S. L., Revello, S., & Bale, T. L. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.0914-13.2013 · Cited by 814

Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

Yehuda, R., & Lehrner, A. (2018) · World Psychiatry · doi:10.1002/wps.20568 · Cited by 730

Intergenerational and transgenerational epigenetic inheritance in animals

Perez, M. F., & Lehner, B. (2019) · Nature Cell Biology · doi:10.1038/s41556-018-0242-9 · Cited by 528

Sex-Specific Placental Responses in Fetal Development

Rosenfeld, C. S. (2015) · Endocrinology · doi:10.1210/en.2015-1227 · Cited by 485

Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity

Öst, A., Lempradl, A., Casas, E., Weigert, M., Tiko, T., Deniz, M., Pantano, L., Boenisch, U., Itskov, P. M., Stoeckius, M., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.005 · Cited by 406

Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm

Sharma, U., Sun, F., Conine, C. C., Reichholf, B., Kukreja, S., Herzog, V. A., Ameres, S. L., & Rando, O. J. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.06.023 · Cited by 446

High-Fat Diet Reprograms the Epigenome of Rat Spermatozoa and Transgenerationally Affects Metabolism of the Offspring

de Castro Barbosa, T., Ingerslev, L. R., Alm, P. S., Versteyhe, S., Massart, J., Rasmussen, M., Donkin, I., Sjögren, R., Mudry, J. M., Vetterli, L., et al. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2015.12.002 · Cited by 417

DNA methylation contributes to natural human variation

Heyn, H., Moran, S., Hernando-Herraez, I., Sayols, S., Gomez, A., Sandoval, J., Monk, D., Hata, K., Marques-Bonet, T., Wang, L., et al. (2013) · Genome Research · doi:10.1101/gr.154187.112 · Cited by 408

Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring

Bromfield, J. J., Schjenken, J. E., Chin, P. Y., Care, A. S., Jasper, M. J., & Robertson, S. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305609111 · Cited by 392

The presence, role and clinical use of spermatozoal RNAs

Jodar, M., Selvaraju, S., Sendler, E. D., Diamond, M. P., Krawetz, S. A., & for the Reproductive Medicine Network (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt031 · Cited by 387

Transgenerational inheritance: Models and mechanisms of non–DNA sequence–based inheritance

Miska, E. A., & Ferguson-Smith, A. C. (2016) · Science · doi:10.1126/science.aaf4945 · Cited by 367

A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line

Soubry, A., Hoyo, C., Jirtle, R. L., & Murphy, S. K. (2014) · BioEssays · doi:10.1002/bies.201300113 · Cited by 373

Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice

Conine, C. C., Sun, F., Song, L., Rivera‐Pérez, J. A., & Rando, O. J. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.06.024 · Cited by 370

Transgenerational Epigenetic Inheritance

Bošković, A., & Rando, O. J. (2018) · Annual Review of Genetics · doi:10.1146/annurev-genet-120417-031404 · Cited by 363

Stability, delivery and functions of human sperm RNAs at fertilization

Sendler, E. D., Johnson, G. D., Mao, S., Goodrich, R. J., Diamond, M. P., Hauser, R. B., & Krawetz, S. A. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt132 · Cited by 338

Parenting from before conception

Lane, M., Robker, R. L., & Robertson, S. A. (2014) · Science · doi:10.1126/science.1254400 · Cited by 304

Mechanisms of epigenetic memory

D’Urso, A., & Brickner, J. H. (2014) · Trends in Genetics · doi:10.1016/j.tig.2014.04.004 · Cited by 294

I’m Eating for Two: Parental Dietary Effects on Offspring Metabolism

Rando, O. J., & Simmons, R. A. (2015) · Cell · doi:10.1016/j.cell.2015.02.021 · Cited by 285

Innate immune memory: a paradigm shift in understanding host defense

Netea, M. G., Latz, E., Mills, K. H. G., & O'Neill, L. A. J. (2015) · Nature Immunology · doi:10.1038/ni.3178 · Cited by 269

Parental Advisory: Maternal and Paternal Stress Can Impact Offspring Neurodevelopment

Chan, J. C., Nugent, B. M., & Bale, T. L. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.10.005 · Cited by 241

Entangled lives: Implications of the developmental origins of health and disease hypothesis for bioarchaeology and the life course

Gowland, R. L. (2015) · American Journal of Physical Anthropology · doi:10.1002/ajpa.22820 · Cited by 245

Animal models of in utero exposure to a high fat diet: A review

Williams, L., Seki, Y., Vuguin, P. M., & Charron, M. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.07.006 · Cited by 234

The Female Response to Seminal Fluid

Schjenken, J. E., & Robertson, S. A. (2020) · Physiological Reviews · doi:10.1152/physrev.00013.2018 · Cited by 219

What is a paternal effect?

Crean, A. J., & Bonduriansky, R. (2014) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2014.07.009 · Cited by 225

Mitochondria: their role in spermatozoa and in male infertility

Boguenet, M., Bouet, P., Spiers, A., Reynier, P., & May‐Panloup, P. (2021) · Human Reproduction Update · doi:10.1093/humupd/dmab001 · Cited by 189

Metabolism and Epigenetics

Janke, R., Dodson, A. E., & Rine, J. (2015) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100814-125544 · Cited by 199

Epigenetic marking of sperm by post-translational modification of histones and protamines

Brunner, A. M., Nanni, P., & Mansuy, I. M. (2014) · Epigenetics & Chromatin · doi:10.1186/1756-8935-7-2 · Cited by 181

Argonautes Promote Male Fertility and Provide a Paternal Memory of Germline Gene Expression in C. elegans

Conine, C. C., Moresco, J. J., Gu, W., Shirayama, M., Conte, D., Yates, J. R., & Mello, C. C. (2013) · Cell · doi:10.1016/j.cell.2013.11.032 · Cited by 178

The contribution of human sperm proteins to the development and epigenome of the preimplantation embryo

Castillo, J., Jodar, M., & Oliva, R. (2018) · Human Reproduction Update · doi:10.1093/humupd/dmy017 · Cited by 181

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

Cropley, J. E., Eaton, S. A., Aiken, A., Young, P. E., Giannoulatou, E., Ho, J. W. K., Buckland, M. E., Keam, S. P., Hutvágner, G., Humphreys, D. T., et al. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.06.008 · Cited by 180

Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information

Sharma, U. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00215 · Cited by 173

Influence of paternal preconception exposures on their offspring: through epigenetics to phenotype.

Day, J., Savani, S., Krempley, B. D., Nguyen, M. H., & Kitlinska, J. B. (2016) · Europe PMC (PubMed Central) · Cited by 154

Maternal age generates phenotypic variation in Caenorhabditis elegans

Perez, M. F., Francesconi, M., Hidalgo-Carcedo, C., & Lehner, B. (2017) · Nature · doi:10.1038/nature25012 · Cited by 151

Elements of morphology: General terms for congenital anomalies

Hennekam, R. C. M., Biesecker, L. G., Allanson, J. E., Hall, J. G., Opitz, J. M., Temple, I. K., & Carey, J. C. (2013) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36249 · Cited by 154

Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes

Cossetti, C., Lugini, L., Astrologo, L., Saggio, I., Fais, S., & Spadafora, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101629 · Cited by 151

Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome

Shea, J. M., Serra, R. W., Carone, B. R., Shulha, H. P., Kucukural, A., Ziller, M. J., Vallaster, M. P., Gu, H., Tapper, A. R., Gardner, P. D., et al. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.11.024 · Cited by 137

Fathers Matter: Why It’s Time to Consider the Impact of Paternal Environmental Exposures on Children’s Health

Braun, J. M., Messerlian, C., & Hauser, R. B. (2017) · Current Epidemiology Reports · doi:10.1007/s40471-017-0098-8 · Cited by 133

Intergenerational Transfer of Epigenetic Information in SpermPreprint

Rando, O. J. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a022988 · Cited by 129

Occurrence and functional significance of the transcriptome in bovine (Bos taurus) spermatozoa

Selvaraju, S., Parthipan, S., Somashekar, L., Kolte, A. P., Binsila, B. K., Arangasamy, A., & Ravindra, J. P. (2017) · Scientific Reports · doi:10.1038/srep42392 · Cited by 124

Recent advances in vertebrate and invertebrate transgenerational immunity in the light of ecology and evolution

Roth, O., Beemelmanns, A., Barribeau, S. M., & Sadd, B. M. (2018) · Heredity · doi:10.1038/s41437-018-0101-2 · Cited by 121

Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compounds

Rissman, E. F., & Adli, M. (2014) · Endocrinology · doi:10.1210/en.2014-1123 · Cited by 113

A history of why fathers’ RNA matters†

Gòdia, M., Swanson, G., & Krawetz, S. A. (2018) · Biology of Reproduction · doi:10.1093/biolre/ioy007 · Cited by 113

The protein and transcript profiles of human semen

Jodar, M., Sendler, E. D., & Krawetz, S. A. (2015) · Cell and Tissue Research · doi:10.1007/s00441-015-2237-1 · Cited by 109

Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary

Morán, S., Martínez‐Cardús, A., Boussios, S., & Esteller, M. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2017.97 · Cited by 104

Multigenerational and transgenerational impact of paternal bisphenol A exposure on male fertility in a mouse model

Rahman, M. S., Pang, W., Ryu, D., Park, Y.-J., & Pang, M. (2020) · Human Reproduction · doi:10.1093/humrep/deaa139 · Cited by 106

Roles of male reproductive tract extracellular vesicles in reproduction

Tamessar, C. T., Trigg, N. A., Nixon, B., Skerrett-Byrne, D. A., Sharkey, D. J., Robertson, S. A., Bromfield, E. G., & Schjenken, J. E. (2020) · American Journal of Reproductive Immunology · doi:10.1111/aji.13338 · Cited by 99

Integrating Ecological and Evolutionary Context in the Study of Maternal Stress

Sheriff, M. J., Bell, A. M., Boonstra, R., Dantzer, B., Lavergne, S. G., McGhee, K. E., MacLeod, K. J., Winandy, L., Zimmer, C., & Love, O. P. (2017) · Integrative and Comparative Biology · doi:10.1093/icb/icx105 · Cited by 95

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

Oliva, R., Castillo, J., Estanyol, J. M., & Ballescà, J. (2015) · Asian Journal of Andrology · doi:10.4103/1008-682x.153302 · Cited by 98

Germ Cell Origins of Posttraumatic Stress Disorder Risk: The Transgenerational Impact of Parental Stress Experience

Rodgers, A. B., & Bale, T. L. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.03.018 · Cited by 91

Consequences of Paternal Nutrition on Offspring Health and Disease

Dimofski, P., Meyre, D., Dreumont, N., & Leininger‐Muller, B. (2021) · Nutrients · doi:10.3390/nu13082818 · Cited by 97

Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk

Heyn, H., Sayols, S., Moutinho, C., Vidal, E., Sanchez-Mut, J. V., Stefánsson, Ó. A., Nadal, E., Morán, S., Eyfjord, J. E., González‐Suárez, E., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.016 · Cited by 87

Epigenetic Mechanisms Affecting Regulation of Energy Balance: Many Questions, Few Answers

Waterland, R. A. (2014) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071813-105315 · Cited by 90

Paternal impact on the life course development of obesity and type 2 diabetes in the offspring

Sharp, G. C., & Lawlor, D. A. (2019) · Diabetologia · doi:10.1007/s00125-019-4919-9 · Cited by 85

Sperm epigenomics: challenges and opportunities

Casas, E., & Vavouri, T. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00330 · Cited by 84

Discovery of a Novel Seminal Fluid Microbiome and Influence of Estrogen Receptor Alpha Genetic Status

Javurek, A. B., Spollen, W. G., Ali, A. M. M., Johnson, S., Lubahn, D. B., Bivens, N. J., Bromert, K. H., Ellersieck, M. R., Givan, S. A., & Rosenfeld, C. S. (2016) · Scientific Reports · doi:10.1038/srep23027 · Cited by 83

Paternal epigenetic programming: evolving metabolic disease risk

Hur, S. S. J., Cropley, J. E., & Suter, C. M. (2017) · Journal of Molecular Endocrinology · doi:10.1530/jme-16-0236 · Cited by 81

Programming of stress pathways: A transgenerational perspective

Constantinof, A., Moisiadis, V. G., & Matthews, S. G. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.10.008 · Cited by 84

Sperm and seminal plasma RNAs: what roles do they play beyond fertilization?

Jodar, M. (2019) · Reproduction · doi:10.1530/rep-18-0639 · Cited by 78

Soma-to-germline RNA communication

Conine, C. C., & Rando, O. J. (2021) · Nature Reviews Genetics · doi:10.1038/s41576-021-00412-1 · Cited by 80

Role of miRNA in the Transmission of Metabolic Diseases Associated With Paternal Diet-Induced Obesity

Dupont, C., Kappeler, L., Saget, S., Grandjean, V., & Lévy, R. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00337 · Cited by 80

Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring

Vallaster, M., Kukreja, S., Bing, X., Ngolab, J., Zhao-Shea, R., Gardner, P. D., Tapper, A. R., & Rando, O. J. (2017) · eLife · doi:10.7554/elife.24771 · Cited by 75

Transfer RNA-derived small RNAs: potential applications as novel biomarkers for disease diagnosis and prognosis

Jia, Y., Tan, W., & Zhou, Y. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-2797 · Cited by 72

What are parental condition‐transfer effects and how can they be detected?

Russell Bonduriansky, A., & Crean, A. J. (2017) · Methods in Ecology and Evolution · doi:10.1111/2041-210x.12848 · Cited by 73

Characterization of Genetic and Epigenetic Variation in Sperm and Red Blood Cells from Adult Hatchery and Natural-Origin Steelhead, Oncorhynchus mykiss

Gavery, M. R., Nichols, K. M., Goetz, G., Middleton, M. A., & Swanson, P. (2018) · G3 Genes Genomes Genetics · doi:10.1534/g3.118.200458 · Cited by 72

The Cell Biology of Genomes: Bringing the Double Helix to Life

Misteli, T. (2013) · Cell · doi:10.1016/j.cell.2013.02.048 · Cited by 71

Current status of sperm functional genomics and its diagnostic potential of fertility in bovine (Bos taurus)

Selvaraju, S., Parthipan, S., Somashekar, L., Binsila, B. K., Kolte, A. P., Arangasamy, A., Ravindra, J. P., & Krawetz, S. A. (2018) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2018.1444816 · Cited by 80

Maternal and paternal preconception exposure to bisphenols and size at birth

Mustieles, V., Williams, P. L., Fernández, M. F., Mínguez‐Alarcón, L., Ford, J. B., Calafat, A. M., Hauser, R. B., Messerlian, C., & Environment and Reproductive Health (EARTH) Study Team (2018) · Human Reproduction · doi:10.1093/humrep/dey234 · Cited by 69

An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome

Ahmed, T., Auble, D., Berkley, J. A., Black, R. E., Ahern, P. P., Hossain, M., Hsieh, A. T., Ireen, S., Arabi, M., & Gordon, J. I. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12487 · Cited by 71

Comparative proteomic network signatures in seminal plasma of infertile men as a function of reactive oxygen species

Agarwal, A. K., Ayaz, A., Samanta, L., Sharma, R. K., Assidi, M., Abuzenadah, A. M., & Sabanegh, E. (2015) · Clinical Proteomics · doi:10.1186/s12014-015-9094-5 · Cited by 68

Preconception and prenatal urinary concentrations of phenols and birth size of singleton infants born to mothers and fathers from the Environment and Reproductive Health (EARTH) study

Messerlian, C., Mustieles, V., Mínguez‐Alarcón, L., Ford, J. B., Calafat, A. M., Souter, I. C., Williams, P. L., & Hauser, R. B. (2018) · Environment International · doi:10.1016/j.envint.2018.02.017 · Cited by 68

Oncogenesis as a Selective Force: Adaptive Evolution in the Face of a Transmissible Cancer

Russell, T., Madsen, T. R. L., Frédéric Thomas, A., Raven, N., Hamede, R., & Újvári, B. (2018) · BioEssays · doi:10.1002/bies.201700146 · Cited by 67

Genomic and proteomic dissection and characterization of the human sperm chromatin

Castillo, J., Amaral, A., Azpiazu, R., Vavouri, T., Estanyol, J. M., Ballescà, J. L., & Oliva, R. (2014) · Molecular Human Reproduction · doi:10.1093/molehr/gau079 · Cited by 64

Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders

Risal, S., Manti, M., Lu, H., Fornes, R., Larsson, H., Benrick, A., Deng, Q., Cesta, C. E., Rosenqvist, M. A., & Stener‐Victorin, E. (2021) · Translational Psychiatry · doi:10.1038/s41398-020-01183-9 · Cited by 61

Epigenetic Inheritance: Intergenerational Effects of Pesticides and Other Endocrine Disruptors on Cancer Development

Nicolella, H. D., & de Assis, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094671 · Cited by 64

Cancer and life-history traits: lessons from host–parasite interactions

Újvári, B., Beckmann, C., Biro, P. A., Arnal, A., Tasiemski, A., Massol, F., Salzet, M., Mery, F., Boidin‐Wichlacz, C., Missé, D., et al. (2016) · Parasitology · doi:10.1017/s0031182016000147 · Cited by 51

Consumption of a high-fat diet alters the seminal fluid and gut microbiomes in male mice

Javurek, A. B., Spollen, W. G., Johnson, S., Bivens, N. J., Bromert, K. H., Givan, S. A., & Rosenfeld, C. S. (2016) · Reproduction Fertility and Development · doi:10.1071/rd16119 · Cited by 55

The Current State of Cephalopod Science and Perspectives on the Most Critical Challenges Ahead From Three Early-Career Researchers

O’Brien, C. E., Roumbedakis, K., & Winkelmann, I. E. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00700 · Cited by 53

Sperm miRNAs— potential mediators of bull age and early embryo development

Wu, C., Blondin, P., Vigneault, C., Labrecque, R., & Sirard, M. (2020) · BMC Genomics · doi:10.1186/s12864-020-07206-5 · Cited by 49

Transgenerational epigenetic inheritance of diabetes risk as a consequence of early nutritional imbalances

Jiménez‐Chillarón, J. C., Ramon‐Krauel, M., Ribó, S., & Díaz, R. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665115004231 · Cited by 49

Paternal and maternal urinary phthalate metabolite concentrations and birth weight of singletons conceived by subfertile couples

Messerlian, C., Braun, J. M., Mínguez‐Alarcón, L., Williams, P. L., Ford, J. B., Mustieles, V., Calafat, A. M., Souter, I. C., Toth, T. L., & Hauser, R. B. (2017) · Environment International · doi:10.1016/j.envint.2017.06.015 · Cited by 46

Understanding the molecular mechanisms of bisphenol A action in spermatozoa

Rahman, M. S., & Pang, M. (2019) · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · doi:10.5653/cerm.2019.00276 · Cited by 46

Spectacular role of epididymis and bio-active cargo of nano-scale exosome in sperm maturation: A review

Ali, W., Deng, K., Bian, Y., Liu, Z., & Zou, H. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114889 · Cited by 50

Paternal and maternal preconception urinary phthalate metabolite concentrations and child behavior

Messerlian, C., Bellinger, D. C., Mínguez‐Alarcón, L., Romano, M. E., Ford, J. B., Williams, P. L., Calafat, A. M., Hauser, R. B., & Braun, J. M. (2017) · Environmental Research · doi:10.1016/j.envres.2017.07.032 · Cited by 46

Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress

Christoforou, E. R., & Sferruzzi-Perri, A. N. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03566-z · Cited by 44

Epigenetic control of variation and stochasticity in metabolic disease

Panzeri, I., & Pospisilik, J. A. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.05.010 · Cited by 50

Paternal overweight is associated with increased breast cancer risk in daughters in a mouse model

Fontelles, C. C., Carney, E., Clarke, J., Nguyen, N. M., Yin, C., Lu, J., Cruz, M. I., Ong, T. P., Hilakivi-Clarke, L. A., & de Assis, S. (2016) · Scientific Reports · doi:10.1038/srep28602 · Cited by 46

Paternal mixtures of urinary concentrations of phthalate metabolites, bisphenol A and parabens in relation to pregnancy outcomes among couples attending a fertility center

Mínguez‐Alarcón, L., Bellavia, A., Gaskins, A. J., Chavarro, J. E., Ford, J. B., Souter, I. C., Calafat, A. M., Hauser, R. B., & Williams, P. L. (2020) · Environment International · doi:10.1016/j.envint.2020.106171 · Cited by 43

Paternal epigenetic effects of population density on locust phase‐related characteristics associated with heat‐shock protein expression

Chen, B., Li, S., Ren, Q., Tong, X., Zhang, X., & Kang, L. (2015) · Molecular Ecology · doi:10.1111/mec.13072 · Cited by 41

Paternal smoking and germ cell death: A mechanistic link to the effects of cigarette smoke on spermatogenesis and possible long-term sequelae in offspring

Esakky, P., & Moley, K. H. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.07.015 · Cited by 41

High-fat Diet Alters Male Seminal Plasma Composition to Impair Female Immune Adaptation for Pregnancy in Mice

Schjenken, J. E., Moldenhauer, L. M., Sharkey, D. J., Chan, H. Y., Chin, P. Y., Fullston, T., McPherson, N. O., & Robertson, S. A. (2021) · Endocrinology · doi:10.1210/endocr/bqab123 · Cited by 44

Ancestral diet transgenerationally influences offspring in a parent-of-origin and sex-specific manner

Emborski, C. A., & Mikheyev, A. S. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2018.0181 · Cited by 43

Sperm RNA Payload: Implications for Intergenerational Epigenetic Inheritance

Liu, S., & Sharma, U. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065889 · Cited by 41

Non-genetic inheritance via the male germline in mammals

Baxter, F., & Drake, A. J. (2019) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2018.0118 · Cited by 41

Mapping the past, present and future research landscape of paternal effects

Rutkowska, J., Lagisz, M., Bonduriansky, R., & Nakagawa, S. (2020) · BMC Biology · doi:10.1186/s12915-020-00892-3 · Cited by 39

Insights into the sperm chromatin and implications for male infertility from a protein perspective

de la Iglesia, A., Jodar, M., Oliva, R., & Castillo, J. (2022) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1588 · Cited by 40

Puberty and the Evolution of Developmental Science

Worthman, C. M., Dockray, S., & Marceau, K. (2019) · Journal of Research on Adolescence · doi:10.1111/jora.12411 · Cited by 40

A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line

Soubry, A., Hoyo, C., Jirtle, R. L., & Murphy, S. K. (2014) · BioEssays · doi:10.1002/bies.201300113 · Cited by 373

Paternal epigenetic inheritance

Rahia Mashoodh, A., & Champagne, F. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816363-4.00006-7 · Cited by 7

Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance

Champagne, F. A. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000808 · Cited by 81

Exploring paternal epigenetic inheritance in mice

Bras, A. L. (2025) · Lab Animal · doi:10.1038/s41684-025-01646-w

Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans

Wang, Y., Liu, H., & Sun, Z. S. (2017) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12322 · Cited by 200