The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

Sebastián, Carlos, Zwaans, Bernadette M.M., Silberman, Dafne M., Gymrek, Melissa, Goren, Alon, Zhong, Lei, Ram, Oren, Truelove, Jessica +16 more·2012·Cell

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  21. RETRACTED ARTICLE: MicroRNA-572/hMOF/Sirt6 regulates the progression of ovarian cancer
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  24. Protein Acetylation as an Integral Part of Metabolism in Cancer Development and Progression
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  26. Strong Involvement of Classical Histone Deacetylases and Mechanistically Distinct Sirtuins in Bellicose Cancers
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  27. Correction: Inhibition of the NAD-Dependent Protein Deacetylase SIRT2 Induces Granulocytic Differentiation in Human Leukemia Cells
    Yoshitaka Sunami, Marito Araki, Yumi Hironaka, Soji Morishita, Masaki Kobayashi, Ei Leen Liew, Yoko Edahiro, Miyuki Tsutsui, Akimichi Ohsaka, Norio Komatsu · 2013 · PLoS ONE
  28. Binding to nucleosome poises SIRT6 for histone H3 de-acetylation
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  29. Nuclear SIRT6 depletion activates LINE1-cGAS-STING pathway to induce PASMCs senescence in hypoxic pulmonary hypertension
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    Zoltan I. Ungvari, Otília Menyhárt, Alberto Ocana, Andrea Lehoczki, Mónika Fekete, Giampaolo Bianchini, Balázs Győrffy · 2026 · GeroScience
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  36. Metabolic Changes and Their Characterization
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  52. Interaction Between Cellular Metabolic States and Chromatin Dynamics
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