Acetate Dependence of Tumors

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Items 301–400 of 678

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    Simona D’Aprile, Simona Denaro, Anna Gervasi, Nunzio Vicario, Rosalba Parenti · 2025 · Frontiers in Cell and Developmental Biology
  2. Altered Mitochondrial Signalling and Metabolism in Cancer
    Esita Chattopadhyay, Bidyut Roy · 2017 · Frontiers in Oncology
  3. Integration of transcriptional and metabolic control in macrophage activation
    Gioacchino Natoli, Francesco Pileri, Francesco Gualdrini, Serena Ghisletti · 2021 · EMBO Reports
  4. Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
    Sujin Park, Dirk Mossmann, Qian Chen, Xueya Wang, Eva Dazert, Marco Colombi, Alexander Schmidt, Brendan M Ryback, Charlotte K.Y. Ng, Luigi Terracciano et al. · 2022 · Molecular Cell
  5. Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics
    Philippe Marchetti, Pierre Guerreschi, Laurent Mortier, Jérôme Kluza · 2015 · International Journal of Cell Biology
  6. Deciphering the Warburg Effect: Metabolic Reprogramming, Epigenetic Remodeling, and Cell Dedifferentiation
    Albert Mao Li, Jiangbin Ye · 2023 · Annual Review of Cancer Biology
  7. ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
    Sabina I. Hlavaty, Kelsey Salcido, Katherine A. Pniewski, Dzmitry Mukha, Weili Ma, Toshitha Kannan, Joel A. Cassel, Yellamelli V. V. Srikanth, Qin Liu, Andrew V. Kossenkov et al. · 2024 · Cell Reports
  8. Acetate promotes SNAI1 expression by ACSS2-mediated histone acetylation under glucose limitation in renal cell carcinoma cell
    Yao Lv, Linying Jiang, Fuxing Zhang, Minghua Li, Bo Yang, Fangting Zhang, Xiaoqiang Guo · 2020 · Bioscience Reports
  9. Tumor Microenvironment-Derived Metabolites: A Guide to Find New Metabolic Therapeutic Targets and Biomarkers
    Juan Carlos García‐Cañaveras, Agustín Lahoz · 2021 · Cancers
  10. Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance
    Ayenachew Bezawork‐Geleta, James Dimou, Matthew J. Watt · 2022 · Frontiers in Oncology
  11. Hypoxic adaptation of mitochondria and its impact on tumor cell function
    Martin Benej, Ioanna Papandreou, Nicholas C. Denko · 2024 · Seminars in Cancer Biology
  12. Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma
    Shaojin Zhang, Juanjuan He, Zhankui Jia, Zechen Yan, Jinjian Yang · 2018 · Urologic Oncology Seminars and Original Investigations
  13. Moonlighting Metabolic Enzymes in Cancer: New Perspectives on the Redox Code
    Jingwen Jiang, Liyuan Peng, Kui Wang, Canhua Huang · 2020 · Antioxidants and Redox Signaling
  14. Cancer metabolism within tumor microenvironments
    Sho Aki, Ryuichi Nakahara, Keisuke Maeda, Tsuyoshi Osawa · 2023 · Biochimica et Biophysica Acta (BBA) - General Subjects
  15. Developmental roles of protein N‐terminal acetylation
    Rui Duarte Silva, Rui Gonçalo Martinho · 2015 · PROTEOMICS
  16. Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns
    Saioa Márquez, José Javier Fernández, Cristina Mancebo, Carmen Herrero-Sánchez, Sara Alonso, Tito Alejandro Sandoval, Macarena Rodríguez-Prados, Juan R. Cubillos‐Ruiz, Olimpio Montero, Nieves Fernández et al. · 2019 · Cell Reports
  17. Acetate Promotes a Differential Energy Metabolic Response in Human HCT 116 and COLO 205 Colon Cancer Cells Impacting Cancer Cell Growth and Invasiveness
    Sara Rodríguez‐Enríquez, Diana Xochiquetzal Robledo‐Cadena, Juan Carlos Gallardo‐Pérez, Silvia Cecilia Pacheco-Velázquez, Citlali Vázquez, Emma Saavedra, Jorge Luis Vargas-Navarro, Betsy Alejandra Blanco-Carpintero, Álvaro Marín‐Hernández, Ricardo Jasso‐Chávez et al. · 2021 · Frontiers in Oncology
  18. Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation
    Ying Yi, Xianchun Lan, Yinglei Li, Chenchao Yan, Jing Lv, Tianzhe Zhang, Wei Jiang · 2023 · Developmental Cell
  19. Microbiota as the unifying factor behind the hallmarks of cancer
    Iva Benešová, Ľudmila Křížová, Miloslav Kverka · 2023 · Journal of Cancer Research and Clinical Oncology
  20. Regulation of acetyl-CoA biosynthesis via an intertwined acetyl-CoA synthetase/acetyltransferase complex
    Liujuan Zheng, Yifei Du, Wieland Steinchen, Mathias Girbig, Frank Abendroth, Ekaterina Jalomo-Khayrova, Patricia Bedrunka, Isabelle Bekeredjian‐Ding, Christopher-Nils Mais, Georg K. A. Hochberg et al. · 2025 · Nature Communications
  21. Carbon Isotopomer Analysis with Non-Unifom Sampling HSQC NMR for Cell Extract and Live Cell Metabolomics Studies
    Su-Jin Lee, He Wen, Yong An, Jin Wook Cha, Yoon‐Joo Ko, Sven G. Hyberts, Sunghyouk Park · 2016 · Analytical Chemistry
  22. Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux
    Jarmon G. Lees, Timothy S. Cliff, Amanda Gammilonghi, James G. Ryall, Stephen Dalton, David K. Gardner, Alexandra J. Harvey · 2019 · Stem Cells International
  23. The combined use of 1H and 2D NMR‐based metabolomics and chemometrics for non‐targeted screening of biomarkers and identification of reconstituted milk
    Jing Cui, Dan Zhu, Meicheng Su, Dongfei Tan, Xia Zhang, Man Jia, Gang Chen · 2019 · Journal of the Science of Food and Agriculture
  24. Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
    Nuria Vilaplana‐Lopera, Vincent Cuminetti, Ruba Omar Mohammed Almaghrabi, Grigorios Papatzikas, Ashok Kumar Rout, Mark Jeeves, Elena González, Yara Alyahyawi, Alan Cunningham, Ayşegül Erdem et al. · 2022 · eLife
  25. Metabolic adaptation of tissues to stress releases metabolites influencing innate immunity
    Philippe Naquet, Caroline Giessner, Franck Galland · 2015 · Current Opinion in Immunology
  26. Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection
    Samad A. Ibitokou, Brian Dillon, Mala Sinha, Bartosz Szczęsny, Anahi De Jesus Delgadillo, Doaa Reda Abdelrahman, Csaba Szabó, Lutfi A. Abu-Elheiga, Craig C. Porter, Demidmaa Tuvdendorj et al. · 2017 · The Journal of Immunology
  27. Pharmacometabonomics Analysis Reveals Serum Formate and Acetate Potentially Associated with Varying Response to Gemcitabine-Carboplatin Chemotherapy in Metastatic Breast Cancer Patients
    Limiao Jiang, Soo Chin Lee, Thian C. Ng · 2018 · Journal of Proteome Research
  28. Metabolism of T Lymphocytes in Health and Disease
    Timo Gaber, Yuling Chen, Pierre-Louis Krauß, Frank Buttgereit · 2018 · International review of cytology
  29. A rapid method for quantifying free and bound acetate based on alkylation and GC-MS analysis
    Sergey Tumanov, Vinay Bulusu, Eyal Gottlieb, Jurre J. Kamphorst · 2016 · Cancer & Metabolism
  30. Potassium shapes antitumor immunity
    Francesc Baixauli, Matteo Villa, Erika L. Pearce · 2019 · Science
  31. Acetyl-CoA synthetases ACSS1 and ACSS2 are 4-hydroxytamoxifen responsive factors that promote survival in tamoxifen treated and estrogen deprived cells
    Sarah Calhoun, Lei Duan, Carl G. Maki · 2022 · Translational Oncology
  32. A review on the role of fatty acids in colorectal cancer progression
    Malvina Hoxha, Bruno Zappacosta · 2022 · Frontiers in Pharmacology
  33. Antibody-Free Fluorine-Assisted Metabolic Sequencing of RNA N 4‑Acetylcytidine
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    Jinqiang Zhang, Melody Baddoo, Chang Han, Michael J. Strong, Jennifer Cvitanovic, Krzysztof Moroz, Srikanta Dash, Erik K. Flemington, Tong Wu · 2016 · Oncotarget
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  36. Short-chain fatty acids: key antiviral mediators of gut microbiota
    Zhiqiang Xu, Tao Wang, Yanjin Wang, Yongfeng Li, Yuan Sun, Hua‐Ji Qiu · 2025 · Frontiers in Immunology
  37. The peculiarities of cancer cell metabolism: A route to metastasization and a target for therapy
    Tiago M. A. Carvalho, Henrique J. Cardoso, Marília I. Figueira, Cátia Vicente Vaz, Sílvia Socorro · 2019 · European Journal of Medicinal Chemistry
  38. Aberrant lipid metabolism reprogramming and immune microenvironment for gastric cancer: a literature review
    Mengying Cui, Xing Yi, Danxia Zhu, Jun Wu · 2021 · Translational Cancer Research
  39. A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasis
    Jiajun Fu, Fengjiao Hu, Tengfei Ma, Wenjie Zhao, Han Tian, Yan Zhang, Manli Hu, Junjie Zhou, Yanfang Zhang, Chongshu Jian et al. · 2021 · Hepatology
  40. Nutritional Epigenetics in Cancer
    María J. Barrero, Paloma Cejas, Henry W. Long, Ana Ramı́rez de Molina · 2022 · Advances in Nutrition
  41. Lipid metabolic vulnerabilities of multiple myeloma
    Roberta Torcasio, Maria Eugenia Gallo Cantafio, Raissa Kaori Ikeda, Ludovica Ganino, Giuseppe Viglietto, Nicola Amodio · 2023 · Clinical and Experimental Medicine
  42. MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy
    Chloé Najac, Sabrina M. Ronen · 2016 · Topics in Magnetic Resonance Imaging
  43. mTOR-Rictor-EGFR axis in oncogenesis and diagnosis of glioblastoma multiforme
    Mekala Janaki Ramaiah, Rohil Kumar Kurappalli · 2021 · Molecular Biology Reports
  44. Serine starvation silences estrogen receptor signaling through histone hypoacetylation
    Albert Mao Li, Bo He, Dimitris Karagiannis, Yang Li, Haowen Jiang, Preethi Srinivasan, Yaniel Ramirez, Meng-Ning Zhou, Christina N. Curtis, Joshua James Gruber et al. · 2023 · Proceedings of the National Academy of Sciences
  45. ACSS2 controls PPARγ activity homeostasis to potentiate adipose-tissue plasticity
    Nuo Chen, Ming Zhao, Nan Wu, Yaxin Guo, Baihui Cao, Bing Zhan, Yubin Li, Tian Zhou, Faliang Zhu, Chun Hua Guo et al. · 2024 · Cell Death and Differentiation
  46. The effects of the ketone body β-hydroxybutyrate on isolated rat ventricular myocyte excitation-contraction coupling
    Matthew Klos, Sherry Morgenstern, Kayla Hicks, Shreyas Suresh, Eric J. Devaney · 2018 · Archives of Biochemistry and Biophysics
  47. Intermediary metabolism: An intricate network at the crossroads of cell fate and function
    Leonardo M. R. Ferreira, Albert Mao Li, Teresa L. Serafim, Margarida C.M. Sobral, Maria Carmen Alpoim, Ana M. Urbano · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  48. Plasmodium falciparum Acetyl-CoA Synthetase Is Essential for Parasite Intraerythrocytic Development and Chromatin Modification
    Isadora Oliveira Prata, Eliana Fernanda Galindo Cubillos, Arne Krüger, Deibs Barbosa, Joaquim Martins, João Carlos Setúbal, Gerhard Wunderlich · 2021 · ACS Infectious Diseases
  49. Quorum sensing-activated phenylalanine metabolism drives OMV biogenesis to enhance mosquito commensal colonization resistance to Plasmodium
    Yongmao Jiang, Han Gao, Lihua Wang, Wenqian Hu, Guandong Wang, Sibao Wang · 2023 · Cell Host & Microbe
  50. Cell surface GRP78 promotes tumor cell histone acetylation through metabolic reprogramming: a mechanism which modulates the Warburg effect
    Udhayakumar Gopal, Salvatore Vincent Pizzo · 2017 · Oncotarget
  51. Metabolic checkpoints and novel approaches for immunotherapy against cancer
    Yiming Li, Juan Tang, Jian‐Li Jiang, Zhi‐Nan Chen · 2021 · International Journal of Cancer
  52. Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2
    Yidan Liang, Lai Yi, Ping Deng, Liting Wang, Yang Yue, Hui Wang, Tian Li, Jia Xie, Mengyan Chen, Yan Luo et al. · 2021 · Ecotoxicology and Environmental Safety
  53. DAXX drives de novo lipogenesis and contributes to tumorigenesis
    Iqbal Mahmud, Gui-Mei Tian, Jia Wang, Tarun E. Hutchinson, Brandon J. Kim, Nikee Awasthee, Seth Hale, Cheng-Cheng Meng, A. Moore, Li-Ming Zhao et al. · 2023 · Nature Communications
  54. Metabolic Intermediates in Tumorigenesis and Progression
    Yuchen He, Menghui Gao, Haosheng Tang, Yiqu Cao, Shuang Liu, Yongguang Tao · 2019 · International Journal of Biological Sciences
  55. Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate
    Yu Cao, Yang Zhao, Tan Deng, Qi‐Gang Zhou, Gang Hu, Zhuang‐Li Hu, Yan-Yi Jiang, Xiaohan Yang, Fang Wang, Peng-Fei Wu et al. · 2025 · Cell Metabolism
  56. Investigational new drugs for brain cancer
    Verena Staedtke, Ren-Yuan Bai, John Laterra · 2016 · Expert Opinion on Investigational Drugs
  57. Reciprocal regulation of phosphatidylcholine synthesis and H3K36 methylation programs metabolic adaptation
    Wen Fang, Yibing Zhu, Sen Yang, Xiaomeng Tong, Cunqi Ye · 2022 · Cell Reports
  58. Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells
    Emily M. Esquea, Lorela Ciraku, Riley G. Young, Jessica Merzy, Alexandra N. Talarico, Nusaiba N. Ahmed, Mangalam Karuppiah, Anna Ramesh, Adam G. Chatoff, Claudia Veronica Da Silva Crispim et al. · 2024 · Frontiers in Pharmacology
  59. TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth
    Anant Shah, Tiffany A. Melhuish, Todd E. Fox, Henry F. Frierson, David Wotton · 2019 · Genes & Development
  60. The fuel and engine: The roles of reprogrammed metabolism in metastasis of primary liver cancer
    Wenwei Zhu, Ming Lü, Xiangyu Wang, Zhou Xu, Chao Gao, Lun–Xiu Qin · 2020 · Genes & Diseases
  61. Diagnostic Value of1H NMR-Based Metabolomics in Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Breast Cancer
    Hanaa M. Morad, Mohamed M. Abou‐Elzahab, Salah Aref, Ahmed M.A. El-Sokkary · 2022 · ACS Omega
  62. Acetate nourishes stressed tumour cells
    Gemma K. Alderton · 2015 · Nature reviews. Cancer
  63. Interrogating Metabolism in Brain Cancer
    Travis C. Salzillo, Jingzhe Hu, Linda Nguyen, Nicholas Whiting, Jae-Hyuk Lee, Joseph Weygand, Prasanta Dutta, Shivanand Pudakalakatti, Niki Marie Zacharias, Seth T. Gammon et al. · 2016 · Magnetic Resonance Imaging Clinics of North America
  64. Design, synthesis and biological evaluation of novel spiro-pentacylamides as acetyl-CoA carboxylase inhibitors
    Qiangqiang Wei, Liankuo Mei, Yifei Yang, Hui Ma, Hongyi Chen, Huibin Zhang, Jinpei Zhou · 2018 · Bioorganic & Medicinal Chemistry
  65. Acetic acid is an oxidative stressor in gastric cancer cells
    Masahiko Terasaki, Hiromu Ito, Hiromi Kurokawa, Masato Tamura, Susumu Okabe, Hirofumi Matsui, Ichinosuke Hyodo · 2018 · Journal of Clinical Biochemistry and Nutrition
  66. NASH, Fibrosis and Hepatocellular Carcinoma: Lipid Synthesis and Glutamine/Acetate Signaling
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  67. HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma
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  69. Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy
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  70. Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket
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  74. Gut Microbe Rikenellaceae_RC9_gut_group and Knoellia ‐Mediated Acetic Acid Regulates Glucose and Lipid Metabolism in the Muscle of Freshwater Drum ( Aplodinotus grunniens ) Under High‐Fat Diets
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