Acetate Dependence of Tumors
Comerford, Sarah A., Huang, Zhiguang, Du, Xinlin, Wang, Yun, Cai, Ling, Witkiewicz, Agnes K., Walters, Holly, Tantawy, Mohammed N., Fu, Allie, Manning, H. Charles, Horton, Jay D., Hammer, Robert E., McKnight, Steven L., Tu, Benjamin P.·2014·Cell
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- InterFeriNg with Acetγlation: Stress-Levels of Acetate Improve Memory T Cell FunctionCaroline A. Lewis, Matthew G. Vander Heiden · 2016 · Immunity
- Energy Metabolism and EpigeneticsScott J. Bultman · 2017 · Springer eBooks
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- Electron transfer dictates metabolic reprogramming in proliferating cells under hypoxiaYuanyuan Wang, Miao Liu, Yuxia Ruan, Qiaoyun Chu, Yanfen Cui, Ceshi Chen, Guoguang Ying, Binghui Li · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Genome-Driven Targeted Cancer TherapyShayesteh R. Ferdosi · 2017
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- De Novo Acetate Production is Coupled to Central Carbon Metabolism in MammalsXiaojing Liu, Daniel E. Cooper, Ahmad A. Cluntun, Marc O. Warmoes, Steven Zhao, Michael A. Reid, Juan Liu, Kathryn E. Wellen, David G. Kirsch, Jason W. Locasale · 2018 · SSRN Electronic Journal
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- Faculty Opinions recommendation of Alcohol metabolism contributes to brain histone acetylation.Dorit Ron A · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- ACSS2-Mediated Deacetylation of Autophagy Proteins Inhibits Malignancy of Epithelial Ovarian Cancer by Inhibiting GlycolysisYang Jiang, Bingshu Li, Ming Hu, Xiaoyi Zhang, Jingchun Liu, Ying Wang, Haoyu Wang, Jiaxin Peng, Likun Gao, Li Hong · 2022 · SSRN Electronic Journal
- KATOBA IN MUNA SOCIETYAida Hayani, Zaenuddin Hudi Prasojo · 2021 · Thaqafiyyat Jurnal Bahasa Peradaban dan Informasi Islam
- The role of fatty acids metabolism on cancer progression and therapeutics developmentCatarina Moreira-Barbosa, Andreia Matos, Rui Fernandes, Miguel Mendes-Ferreira, Rafaela C. Rodrigues, Tânia Cruz, Ângela M. Costa, Ana Patrícia Cardoso, Carmen Ghilardi, María José Oliveira et al. · 2022 · Elsevier eBooks
- Combined targeting autophagy and metabolism for cancer therapyGarima Tripathi, Shambhavi Mishra, Ambarish Priyadarshan, Satya Narayan Sahu, Anil Kumar Singh, Abhijeet Kumar · 2022 · Elsevier eBooks
- Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stressesJinyang Wang, Yaxin Wen, Wentao Zhao, Yan Ting Zhang, Furong Lin, Cong Ouyang, Huihui Wang, Lizheng Yao, Huanhuan Ma, Yue Zhuo et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Data from Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer GrowthKatelyn D. Miller, Katherine A. Pniewski, Caroline E. Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco‐Silva, Jessica C. Casciano, Tomas M. Aramburu, Yellamelli V. V. Srikanth, Joel A. Cassel et al. · 2023
- Data from Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and ChemoresistanceZi‐Qi Zheng, Zhi‐Xuan Li, Jia-Li Guan, Xu Liu, Junyan Li, Yue Chen, Li Lin, Jia Kou, Jia‐Wei Lv, Lulu Zhang et al. · 2023
- Data from Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and ChemoresistanceZi‐Qi Zheng, Zhi‐Xuan Li, Jia-Li Guan, Xu Liu, Junyan Li, Yue Chen, Li Lin, Jia Kou, Jia‐Wei Lv, Lulu Zhang et al. · 2023
- Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stressesJinyang Wang, Yaxin Wen, Wentao Zhao, Yan Ting Zhang, Furong Lin, Cong Ouyang, Huihui Wang, Lizheng Yao, Huanhuan Ma, Yue Zhuo et al. · 2023 · eLife
- Biochemical Changes in the Local Onco-SpherePhei Er Saw, Erwei Song · 2023 · Springer eBooks
- Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stressesJinyang Wang, Yaxin Wen, Wentao Zhao, Yan Zhang, Furong Lin, Cong Ouyang, Huihui Wang, Lizheng Yao, Huanhuan Ma, Yue Zhuo et al. · 2023 · eLife
- The adiposity of CRLM before targeted therapy initiation may serve as a marker to distinguish KRAS mutation status:A retrospective studyRenzhe Xiao, Ning Wang, Wei Xiao, Yulin Liu · 2024 · Research Square
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- An improved synthesis of alkyl AMP estersTaiwo E. Esan, Charles L. Lail, Drashti G. Daraji, Damian J. Krysan, Timothy J. Hagen · 2024 · Tetrahedron Letters
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- Fatty acid metabolism in colon cancer patientsS. A. H. Jasim, Reem N. Alsawaf, Mohammed A.H. Alobeady · 2025 · Regulatory Mechanisms in Biosystems
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- Antitumor Immunotoxin Activity is Enhanced by Escherichia coli csrB-Promoter ExpressionSeyeon Hong, Sung‐Gwon Lee, Dogeun Lee, Jihyeon Kim, Mi‐Ryoung Song, Daejin Lim · 2025 · Research Square
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- Additional file 1 of Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasmsGu, Danyang, Ye, Mujie, Zhu, Guoqin, Jian’an Bai, Chen, Jinhao, Lijun Yan, Yu, Ping, Feiyu Lu, Hu, Chunhua, Zhong, Yuan et al. · 2024 · Figshare
- Additional file 2 of Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasmsGu, Danyang, Ye, Mujie, Zhu, Guoqin, Jian’an Bai, Chen, Jinhao, Lijun Yan, Yu, Ping, Feiyu Lu, Hu, Chunhua, Zhong, Yuan et al. · 2024 · Figshare
- Additional file 1 of Prognostic PET [11C]-acetate uptake is associated with hypoxia gene expression in patients with late-stage hepatocellular carcinoma – a bench to bed studyKeith Wan-Hang Chiu, Kel Vin Tan, Yang, Xinxiang, Zhu, Xiaoqiang, Shi, Jingjing, Chiang, Chi-Leung, Chan, Lawrence, Hui, Yuan, Khong, Pek-Lan, Man, Kwan et al. · 2024 · Figshare
- Additional file 2 of ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s diseaseYingbin Lin, Anlan Lin, Cai, Lili, Huang, Weibin, Shanzhi Yan, Yuanxiang Wei, Ruan, Xinglin, Fang, Wenting, Dai, Xiaoman, Cheng, Jinbo et al. · 2024 · Figshare
- Additional file 2 of Prognostic PET [11C]-acetate uptake is associated with hypoxia gene expression in patients with late-stage hepatocellular carcinoma – a bench to bed studyChiu, Keith Wan Hang, Tan, Kel Vin, Yang, Xinxiang, Zhu, Xiaoqiang, Shi, Jingjing, Chiang, Chi-Leung, Chan, Lawrence, Hui Yuan, Khong, Pek-Lan, Man, Kwan et al. · 2024 · Figshare
- Additional file 1 of ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s diseaseYingbin Lin, Anlan Lin, Cai, Lili, Huang, Weibin, Shanzhi Yan, Yuanxiang Wei, Ruan, Xinglin, Fang, Wenting, Dai, Xiaoman, Cheng, Jinbo et al. · 2024 · Figshare
- Additional file 3 of ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s diseaseYingbin Lin, Anlan Lin, Cai, Lili, Huang, Weibin, Shanzhi Yan, Yuanxiang Wei, Ruan, Xinglin, Fang, Wenting, Dai, Xiaoman, Cheng, Jinbo et al. · 2024 · Figshare
- Additional file 4 of ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s diseaseYingbin Lin, Anlan Lin, Cai, Lili, Huang, Weibin, Shanzhi Yan, Yuanxiang Wei, Ruan, Xinglin, Fang, Wenting, Dai, Xiaoman, Cheng, Jinbo et al. · 2024 · Figshare
- Additional file 5 of ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s diseaseYingbin Lin, Anlan Lin, Cai, Lili, Huang, Weibin, Shanzhi Yan, Yuanxiang Wei, Ruan, Xinglin, Fang, Wenting, Dai, Xiaoman, Cheng, Jinbo et al. · 2024 · Figshare
- Processes and therapeutic perspectives of acylation modifications of lysine and cysteine in tumorsJialin Jiang, Jiabin Chen, Shuhang Huang, Yue Tian, Lanyu Liu, Jiahui Yao, Yuzhu Zhang, Can Jiang, Xingting Zhang, Na Han et al. · 2026 · Cell Communication and Signaling
- AcetateHiroshi Ohno · 2026 · Trends in Endocrinology and Metabolism
- Silent chromatin dynamics upon major metabolic transitionsMicol Guidi · 2015 · theses.fr (ABES)
- Regulation of Autophagy by Acetyl Coenzime A : From the Mechanisms to a Revised Definition of Caloric Restriction MimeticsFederico Pietrocola · 2015 · theses.fr (ABES)
- Vanin-1 et la réponse mésenchymateuse à un stress inflammatoire ou tumoralCaroline Giessner · 2015 · theses.fr (ABES)
- Rôle de l'autophagie dans l'émergence des cellules souches cancéreuses : implication du métabolismeMouradi El-Hout · 2019 · theses.fr (ABES)
- Etude de la réponse au stress oxydant de hépatocarcinomes présentant une hyperactivation de la voie β-caténineMathilde Savall · 2020 · theses.fr (ABES)
- Rôle de RelB et de sa phosphorylation sur la sérine 472 dans les dérégulations du métabolisme in vitro et in vivoClara Benatar · 2021 · theses.fr (ABES)
- Transfert de mitochondries des cellules souches mésenchymateuses aux cellules souches de glioblastome : effets sur le métabolisme et la résistance à la chimiothérapieJean Nakhle · 2020 · theses.fr (ABES)
- Hétérogénéité métabolique des gliomes : apport de la spectroscopie RMN HRMASCaroline Bund · 2020 · theses.fr (ABES)
- The role of acetate in macrophage`s response against Streptococcus pneumoniaeMarina Gomes Machado · 2022 · theses.fr (ABES)
- Biochemical, biophysical and structural study of proteins associated to human diseases : tcDAC2 and ADAT complexElizabeth Ramos‐Morales · 2021 · theses.fr (ABES)
- Optimization of Antifungal 1,5-Diaryl-Pyrazole Acetyl-CoA Synthetase InhibitorsJonah Propp, Jeffrey C. Ferreira, Parisa Enayati, Katy M. Alden, Drashti G. Daraji, Charles L. Lail, Michael E. Heene, Andrew J. Jezewski, Rohan S. Wakade, Damien Castor et al. · 2026 · ACS Omega
- ACSS2 drives Lenvatinib resistance in hepatocellular carcinoma through palmitoylationHao Xu, Hongxia Wang, Shi-Zhe Yu, Tiantian Zou, Sun‐Zhe Xie, Ke-Yu Shen, C H I Zhang, Jianfeng Xu, Jun-Jie Pan, Sami Yang et al. · 2026 · Pharmacological Research
- Acetyl-CoA synthetase 2 nuclear translocation impediment contributes to nickel induced histone hypoacetylation and neurite outgrowth impairmentChao Zhou, Jianbo Zhang, Wei Zhang, Ya Xu, Xiang Mei, Ping Deng, Qinlong Ma, Chunhai Chen, L Zhang, Huifeng Pi et al. · 2026 · Toxicology Letters
- Iron-driven regulation of nucleotide synthesis reveals metabolic vulnerabilities in colorectal cancerLuke Villareal, Yanshan Liang, Young‐Yon Kwon, Sheng Tony Hui, Xiang Xue · 2026 · Genes & Diseases
- Precision metabolic therapy for propionic acidemiaBoopathi Subramaniyan, Fang Lu, Huan Li, Chorlada Paiboonrungruang, Yahui Li, Zhaohui Xiong, Guo-Fang Zhang, Xiaoxin Chen · 2026 · Biochemical Pharmacology
- Blautia coccoides -derived acetate potentiates anti-PD-1 immunotherapy in melanoma by activating cytotoxic CD8 + T cellsZhiwen Zhang, Xiaofeng Liang, Yuyang Tian, Chengyi Li, Xueli Cao, Di Wang, Ansheng Xie, S X Liu, Kefan Lin, Qing Li et al. · 2026 · Journal for ImmunoTherapy of Cancer
- ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatmentLei Wang, Urszula Dougherty, Wenliang He, Lu Gao, Caleb Nwongbouwoh Muefong, Rajesh Sarkar, Jie Du, Ardaman P. Shergill, Hening Lin, Marc Bissonnette et al. · 2026 · iScience
- Integrated landscape of salivary metagenome and multi-biofluid metabolome characterizes a microbial-metabolic axis in upper gastrointestinal cancer progressionShuai Zhang, Nan Zhang, Xiaofeng Zhang, Yanxiu Liu, Yukun Feng, Junling Xiang, Jun Zhang, Hengmin Ma, Youhua Lu, Tao Zhang · 2026 · Microbiome
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- Acetyl-CoA synthetase 2 maintains cytosolic acetyl-CoA homeostasis to preserve mitochondrial integrity and attenuate cardiac dysfunction under chronic β-adrenergic stressToranosuke Sekine, Shunsuke Miura, Tomofumi Misaka, Satoshi Okochi, Ryo Ogawara, Shohei Ichimura, Tetsuro Yokokawa, Masayoshi Oikawa, Satoshi Waguri, Takafumi Ishida et al. · 2026 · Journal of Molecular and Cellular Cardiology Plus
- The interplay between lipid metabolism, cancer progression and anti-cancer immunityChoong‐Hyun Koh, Yoosun Lee, Il‐Kyu Kim, Yeonseok Chung · 2026 · Experimental & Molecular Medicine
- Acetate suppresses tumorigenesis through ACSS2-dependent H2A.Z acetylation in esophageal squamous cell carcinomaZhenhui Chen, Chenghao Li, Yunxi Zhang, Xiangpeng Tan, Yue Zhou, Zhichao Liu, Hongyan Chen, Ning Zhao, Xuanxuan Gou, Wenyan Sun et al. · 2026 · Cell Reports
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- BindingDB Entry 50002803: Design, synthesis and biological evaluation of novel spiro-pentacylamides as acetyl-CoA carboxylase inhibitors.BindingDB · 2020 · UC San Diego