The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
The Principles of Engineering Immune Cells to Treat Cancer
Open accessAbstract
Chimeric antigen receptor (CAR) T cells have proven that engineered immune cells can serve as a powerful new class of cancer therapeutics. Clinical experience has helped to define the major challenges that must be met to make engineered T cells a reliable, safe, and effective platform that can be deployed against a broad range of tumors. The emergence of synthetic biology approaches for cellular engineering is providing us with a broadly expanded set of tools for programming immune cells. We discuss how these tools could be used to design the next generation of smart T cell precision therapeutics.
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Cites
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Cited by
Car t cell immunotherapy for human cancer
June, C. H., O’Connor, R. S., Kawalekar, O. U., Ghassemi, S., & Milone, M. C. (2018) · Science · doi:10.1126/science.aar6711 · Cited by 3,207
Self-citationDefining trained immunity and its role in health and disease
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Engineering Macrophages for Cancer Immunotherapy and Drug Delivery
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Reprogramming human T cell function and specificity with non-viral genome targeting
Roth, T. L., Puig-Saus, C., Yu, R., Shifrut, E., Carnevale, J., Li, P. J., Hiatt, J., Saco, J., Krystofinski, P., Li, H., et al. (2018) · Nature · doi:10.1038/s41586-018-0326-5 · Cited by 839
Targeting cardiac fibrosis with engineered T cells
Aghajanian, H., Kimura, T., Rurik, J. G., Hancock, A. S., Leibowitz, M. S., Li, L., Scholler, J., Monslow, J., Lo, A., Han, W., et al. (2019) · Nature · doi:10.1038/s41586-019-1546-z · Cited by 801
Self-citation
Metadata
- Authors
- Lim, W. A., & June, C. H.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 168
- Issue
- 4
- Pages
- 724-740
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2587691649
- Cited by
- 1,080
- References
- 31
- FWCI
- 50.95
- Type
- journal article
- Language
- en
- Open access
- bronze
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