The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
The Principles of Engineering Immune Cells to Treat Cancer
Open accessAbstract
Chimeric antigen receptor (CAR) T cells have proven that engineered immune cells can serve as a powerful new class of cancer therapeutics. Clinical experience has helped to define the major challenges that must be met to make engineered T cells a reliable, safe, and effective platform that can be deployed against a broad range of tumors. The emergence of synthetic biology approaches for cellular engineering is providing us with a broadly expanded set of tools for programming immune cells. We discuss how these tools could be used to design the next generation of smart T cell precision therapeutics.
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Citations
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Self-citation
Metadata
- Authors
- Lim, W. A., & June, C. H.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 168
- Issue
- 4
- Pages
- 724-740
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2587691649
- Cited by
- 1,080
- References
- 31
- FWCI
- 50.95
- Type
- journal article
- Language
- en
- Open access
- bronze
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