Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

Hoadley, Katherine A., Yau, Christina, Hinoue, Toshinori, Wolf, Denise M., Lazar, Alexander J., Drill, Esther, Shen, Ronglai, Taylor, Alison M., Cherniack, Andrew D., Thorsson, Vésteinn, Akbani, Rehan, Bowlby, Reanne, Wong, Christopher K., Wiznerowicz, Maciej, Sanchez-Vega, Francisco, Robertson, A. Gordon, Schneider, Barbara G., Lawrence, Michael S., Noushmehr, Houtan, Malta, Tathiane M., Caesar-Johnson, Samantha J., Demchok, John A., Felau, Ina, Kasapi, Melpomeni, Ferguson, Martin L., Hutter, Carolyn M., Sofia, Heidi J., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Zhang, Jiashan (Julia), Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Naresh, Rashi, Pihl, Todd, Sun, Qiang, Wan, Yunhu, Wu, Ye, Cho, Juok, DeFreitas, Timothy, Frazer, Scott, Gehlenborg, Nils, Getz, Gad, Heiman, David I., Kim, Jaegil, Lawrence, Michael S., Lin, Pei, Meier, Sam, Noble, Michael S., Saksena, Gordon, Voet, Doug, Zhang, Hailei, Bernard, Brady, Chambwe, Nyasha, Dhankani, Varsha, Knijnenburg, Theo, Kramer, Roger, Leinonen, Kalle, Liu, Yuexin, Miller, Michael, Reynolds, Sheila, Shmulevich, Ilya, Thorsson, Vesteinn, Zhang, Wei, Akbani, Rehan, Broom, Bradley M., Hegde, Apurva M., Ju, Zhenlin, Kanchi, Rupa S., Korkut, Anil, Li, Jun, Liang, Han, Ling, Shiyun, Liu, Wenbin, Lu, Yiling, Mills, Gordon B., Ng, Kwok-Shing, Rao, Arvind, Ryan, Michael, Wang, Jing, Weinstein, John N., Zhang, Jiexin, Abeshouse, Adam, Armenia, Joshua, Chakravarty, Debyani, Chatila, Walid K., de Bruijn, Ino, Gao, Jianjiong, Gross, Benjamin E., Heins, Zachary J., Kundra, Ritika, La, Konnor, Ladanyi, Marc, Luna, Augustin, Nissan, Moriah G., Ochoa, Angelica, Phillips, Sarah M., Reznik, Ed, Sanchez-Vega, Francisco, Sander, Chris, Schultz, Nikolaus, Sheridan, Robert, Sumer, S. Onur, Sun, Yichao, Taylor, Barry S., Wang, Jioajiao, Zhang, Hongxin, Anur, Pavana, Peto, Myron, Spellman, Paul, Benz, Christopher, Stuart, Joshua M., Wong, Christopher K., Yau, Christina, Hayes, D. Neil, Parker, Joel S., Wilkerson, Matthew D., Ally, Adrian, Balasundaram, Miruna, Bowlby, Reanne, Brooks, Denise, Carlsen, Rebecca, Chuah, Eric, Dhalla, Noreen, Holt, Robert, Jones, Steven J.M., Kasaian, Katayoon, Lee, Darlene, Ma, Yussanne, Marra, Marco A., Mayo, Michael, Moore, Richard A., Mungall, Andrew J., Mungall, Karen, Robertson, A. Gordon, Sadeghi, Sara, Schein, Jacqueline E., Sipahimalani, Payal, Tam, Angela, Thiessen, Nina, Tse, Kane, Wong, Tina, Berger, Ashton C., Beroukhim, Rameen, Cherniack, Andrew D., Cibulskis, Carrie, Gabriel, Stacey B., Gao, Galen F., Ha, Gavin, Meyerson, Matthew, Schumacher, Steven E., Shih, Juliann, Kucherlapati, Melanie H., Kucherlapati, Raju S., Baylin, Stephen, Cope, Leslie, Danilova, Ludmila, Bootwalla, Moiz S., Lai, Phillip H., Maglinte, Dennis T., Van Den Berg, David J., Weisenberger, Daniel J., Auman, J. Todd, Balu, Saianand, Bodenheimer, Tom, Fan, Cheng, Hoadley, Katherine A., Hoyle, Alan P., Jefferys, Stuart R., Jones, Corbin D., Meng, Shaowu, Mieczkowski, Piotr A., Mose, Lisle E., Perou, Amy H., Perou, Charles M., Roach, Jeffrey, Shi, Yan, Simons, Janae V., Skelly, Tara, Soloway, Matthew G., Tan, Donghui, Veluvolu, Umadevi, Fan, Huihui, Hinoue, Toshinori, Laird, Peter W., Shen, Hui, Zhou, Wanding, Bellair, Michelle, Chang, Kyle, Covington, Kyle, Creighton, Chad J., Dinh, Huyen, Doddapaneni, HarshaVardhan, Donehower, Lawrence A., Drummond, Jennifer, Gibbs, Richard A., Glenn, Robert, Hale, Walker, Han, Yi, Hu, Jianhong, Korchina, Viktoriya, Lee, Sandra, Lewis, Lora, Li, Wei, Liu, Xiuping, Morgan, Margaret, Morton, Donna, Muzny, Donna, Santibanez, Jireh, Sheth, Margi, Shinbrot, Eve, Wang, Linghua, Wang, Min, Wheeler, David A., Xi, Liu, Zhao, Fengmei, Hess, Julian, Appelbaum, Elizabeth L., Bailey, Matthew, Cordes, Matthew G., Ding, Li, Fronick, Catrina C., Fulton, Lucinda A., Fulton, Robert S., Kandoth, Cyriac, Mardis, Elaine R., McLellan, Michael D., Miller, Christopher A., Schmidt, Heather K., Wilson, Richard K., Crain, Daniel, Curley, Erin, Gardner, Johanna, Lau, Kevin, Mallery, David, Morris, Scott, Paulauskis, Joseph, Penny, Robert, Shelton, Candace, Shelton, Troy, Sherman, Mark, Thompson, Eric, Yena, Peggy, Bowen, Jay, Gastier-Foster, Julie M., Gerken, Mark, Leraas, Kristen M., Lichtenberg, Tara M., Ramirez, Nilsa C., Wise, Lisa, Zmuda, Erik, Corcoran, Niall, Costello, Tony, Hovens, Christopher, Carvalho, Andre L., de Carvalho, Ana C., Fregnani, José H., Longatto-Filho, Adhemar, Reis, Rui M., Scapulatempo-Neto, Cristovam, Silveira, Henrique C.S., Vidal, Daniel O., Burnette, Andrew, Eschbacher, Jennifer, Hermes, Beth, Noss, Ardene, Singh, Rosy, Anderson, Matthew L., Castro, Patricia D., Ittmann, Michael, Huntsman, David, Kohl, Bernard, Le, Xuan, Thorp, Richard, Andry, Chris, Duffy, Elizabeth R., Lyadov, Vladimir, Paklina, Oxana, Setdikova, Galiya, Shabunin, Alexey, Tavobilov, Mikhail, McPherson, Christopher, Warnick, Ronald, Berkowitz, Ross, Cramer, Daniel, Feltmate, Colleen, Horowitz, Neil, Kibel, Adam, Muto, Michael, Raut, Chandrajit P., Malykh, Andrei, Barnholtz-Sloan, Jill S., Barrett, Wendi, Devine, Karen, Fulop, Jordonna, Ostrom, Quinn T., Shimmel, Kristen, Wolinsky, Yingli, Sloan, Andrew E., De Rose, Agostino, Giuliante, Felice, Goodman, Marc, Karlan, Beth Y., Hagedorn, Curt H., Eckman, John, Harr, Jodi, Myers, Jerome, Tucker, Kelinda, Zach, Leigh Anne, Deyarmin, Brenda, Hu, Hai, Kvecher, Leonid, Larson, Caroline, Mural, Richard J., Somiari, Stella, Vicha, Ales, Zelinka, Tomas, Bennett, Joseph, Iacocca, Mary, Rabeno, Brenda, Swanson, Patricia, Latour, Mathieu, Lacombe, Louis, Têtu, Bernard, Bergeron, Alain, McGraw, Mary, Staugaitis, Susan M., Chabot, John, Hibshoosh, Hanina, Sepulveda, Antonia, Su, Tao, Wang, Timothy, Potapova, Olga, Voronina, Olga, Desjardins, Laurence, Mariani, Odette, Roman-Roman, Sergio, Sastre, Xavier, Stern, Marc-Henri, Cheng, Feixiong, Signoretti, Sabina, Berchuck, Andrew, Bigner, Darell, Lipp, Eric, Marks, Jeffrey, McCall, Shannon, McLendon, Roger, Secord, Angeles, Sharp, Alexis, Behera, Madhusmita, Brat, Daniel J., Chen, Amy, Delman, Keith, Force, Seth, Khuri, Fadlo, Magliocca, Kelly, Maithel, Shishir, Olson, Jeffrey J., Owonikoko, Taofeek, Pickens, Alan, Ramalingam, Suresh, Shin, Dong M., Sica, Gabriel, Van Meir, Erwin G., Zhang, Hongzheng, Eijckenboom, Wil, Gillis, Ad, Korpershoek, Esther, Looijenga, Leendert, Oosterhuis, Wolter, Stoop, Hans, van Kessel, Kim E., Zwarthoff, Ellen C., Calatozzolo, Chiara, Cuppini, Lucia, Cuzzubbo, Stefania, DiMeco, Francesco, Finocchiaro, Gaetano, Mattei, Luca, Perin, Alessandro, Pollo, Bianca, Chen, Chu, Houck, John, Lohavanichbutr, Pawadee, Hartmann, Arndt, Stoehr, Christine, Stoehr, Robert, Taubert, Helge, Wach, Sven, Wullich, Bernd, Kycler, Witold, Murawa, Dawid, Wiznerowicz, Maciej, Chung, Ki, Edenfield, W. Jeffrey, Martin, Julie, Baudin, Eric, Bubley, Glenn, Bueno, Raphael, De Rienzo, Assunta, Richards, William G., Kalkanis, Steven, Mikkelsen, Tom, Noushmehr, Houtan, Scarpace, Lisa, Girard, Nicolas, Aymerich, Marta, Campo, Elias, Giné, Eva, Guillermo, Armando López, Van Bang, Nguyen, Hanh, Phan Thi, Phu, Bui Duc, Tang, Yufang, Colman, Howard, Evason, Kimberley, Dottino, Peter R., Martignetti, John A., Gabra, Hani, Juhl, Hartmut, Akeredolu, Teniola, Stepa, Serghei, Hoon, Dave, Ahn, Keunsoo, Kang, Koo Jeong, Beuschlein, Felix, Breggia, Anne, Birrer, Michael, Bell, Debra, Borad, Mitesh, Bryce, Alan H., Castle, Erik, Chandan, Vishal, Cheville, John, Copland, John A., Farnell, Michael, Flotte, Thomas, Giama, Nasra, Ho, Thai, Kendrick, Michael, Kocher, Jean-Pierre, Kopp, Karla, Moser, Catherine, Nagorney, David, O’Brien, Daniel, O’Neill, Brian Patrick, Patel, Tushar, Petersen, Gloria, Que, Florencia, Rivera, Michael, Roberts, Lewis, Smallridge, Robert, Smyrk, Thomas, Stanton, Melissa, Thompson, R. Houston, Torbenson, Michael, Yang, Ju Dong, Zhang, Lizhi, Brimo, Fadi, Ajani, Jaffer A., Gonzalez, Ana Maria Angulo, Behrens, Carmen, Bondaruk, olanta, Broaddus, Russell, Czerniak, Bogdan, Esmaeli, Bita, Fujimoto, Junya, Gershenwald, Jeffrey, Guo, Charles, Lazar, Alexander J., Logothetis, Christopher, Meric-Bernstam, Funda, Moran, Cesar, Ramondetta, Lois, Rice, David, Sood, Anil, Tamboli, Pheroze, Thompson, Timothy, Troncoso, Patricia, Tsao, Anne, Wistuba, Ignacio, Carter, Candace, Haydu, Lauren, Hersey, Peter, Jakrot, Valerie, Kakavand, Hojabr, Kefford, Richard, Lee, Kenneth, Long, Georgina, Mann, Graham, Quinn, Michael, Saw, Robyn, Scolyer, Richard, Shannon, Kerwin, Spillane, Andrew, Stretch, Jonathan, Synott, Maria, Thompson, John, Wilmott, James, Al-Ahmadie, Hikmat, Chan, Timothy A., Ghossein, Ronald, Gopalan, Anuradha, Levine, Douglas A., Reuter, Victor, Singer, Samuel, Singh, Bhuvanesh, Tien, Nguyen Viet, Broudy, Thomas, Mirsaidi, Cyrus, Nair, Praveen, Drwiega, Paul, Miller, Judy, Smith, Jennifer, Zaren, Howard, Park, Joong-Won, Hung, Nguyen Phi, Kebebew, Electron, Linehan, W. Marston, Metwalli, Adam R., Pacak, Karel, Pinto, Peter A., Schiffman, Mark, Schmidt, Laura S., Vocke, Cathy D., Wentzensen, Nicolas, Worrell, Robert, Yang, Hannah, Moncrieff, Marc, Goparaju, Chandra, Melamed, Jonathan, Pass, Harvey, Botnariuc, Natalia, Caraman, Irina, Cernat, Mircea, Chemencedji, Inga, Clipca, Adrian, Doruc, Serghei, Gorincioi, Ghenadie, Mura, Sergiu, Pirtac, Maria, Stancul, Irina, Tcaciuc, Diana, Albert, Monique, Alexopoulou, Iakovina, Arnaout, Angel, Bartlett, John, Engel, Jay, Gilbert, Sebastien, Parfitt, Jeremy, Sekhon, Harman, Thomas, George, Rassl, Doris M., Rintoul, Robert C., Bifulco, Carlo, Tamakawa, Raina, Urba, Walter, Hayward, Nicholas, Timmers, Henri, Antenucci, Anna, Facciolo, Francesco, Grazi, Gianluca, Marino, Mirella, Merola, Roberta, de Krijger, Ronald, Gimenez-Roqueplo, Anne-Paule, Piché, Alain, Chevalier, Simone, McKercher, Ginette, Birsoy, Kivanc, Barnett, Gene, Brewer, Cathy, Farver, Carol, Naska, Theresa, Pennell, Nathan A., Raymond, Daniel, Schilero, Cathy, Smolenski, Kathy, Williams, Felicia, Morrison, Carl, Borgia, Jeffrey A., Liptay, Michael J., Pool, Mark, Seder, Christopher W., Junker, Kerstin, Omberg, Larsson, Dinkin, Mikhail, Manikhas, George, Alvaro, Domenico, Bragazzi, Maria Consiglia, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Chesla, David, Cottingham, Sandra, Dubina, Michael, Moiseenko, Fedor, Dhanasekaran, Renumathy, Becker, Karl-Friedrich, Janssen, Klaus-Peter, Slotta-Huspenina, Julia, Abdel-Rahman, Mohamed H., Aziz, Dina, Bell, Sue, Cebulla, Colleen M., Davis, Amy, Duell, Rebecca, Elder, J. Bradley, Hilty, Joe, Kumar, Bahavna, Lang, James, Lehman, Norman L., Mandt, Randy, Nguyen, Phuong, Pilarski, Robert, Rai, Karan, Schoenfield, Lynn, Senecal, Kelly, Wakely, Paul, Hansen, Paul, Lechan, Ronald, Powers, James, Tischler, Arthur, Grizzle, William E., Sexton, Katherine C., Kastl, Alison, Henderson, Joel, Porten, Sima, Waldmann, Jens, Fassnacht, Martin, Asa, Sylvia L., Schadendorf, Dirk, Couce, Marta, Graefen, Markus, Huland, Hartwig, Sauter, Guido, Schlomm, Thorsten, Simon, Ronald, Tennstedt, Pierre, Olabode, Oluwole, Nelson, Mark, Bathe, Oliver, Carroll, Peter R., Chan, June M., Disaia, Philip, Glenn, Pat, Kelley, Robin K., Landen, Charles N., Phillips, Joanna, Prados, Michael, Simko, Jeffry, Smith-McCune, Karen, VandenBerg, Scott, Roggin, Kevin, Fehrenbach, Ashley, Kendler, Ady, Sifri, Suzanne, Steele, Ruth, Jimeno, Antonio, Carey, Francis, Forgie, Ian, Mannelli, Massimo, Carney, Michael, Hernandez, Brenda, Campos, Benito, Herold-Mende, Christel, Jungk, Christin, Unterberg, Andreas, von Deimling, Andreas, Bossler, Aaron, Galbraith, Joseph, Jacobus, Laura, Knudson, Michael, Knutson, Tina, Ma, Deqin, Milhem, Mohammed, Sigmund, Rita, Godwin, Andrew K., Madan, Rashna, Rosenthal, Howard G., Adebamowo, Clement, Adebamowo, Sally N., Boussioutas, Alex, Beer, David, Giordano, Thomas, Mes-Masson, Anne-Marie, Saad, Fred, Bocklage, Therese, Landrum, Lisa, Mannel, Robert, Moore, Kathleen, Moxley, Katherine, Postier, Russel, Walker, Joan, Zuna, Rosemary, Feldman, Michael, Valdivieso, Federico, Dhir, Rajiv, Luketich, James, Pinero, Edna M. Mora, Quintero-Aguilo, Mario, Carlotti, Carlos Gilberto, Dos Santos, Jose Sebastião, Kemp, Rafael, Sankarankuty, Ajith, Tirapelli, Daniela, Catto, James, Agnew, Kathy, Swisher, Elizabeth, Creaney, Jenette, Robinson, Bruce, Shelley, Carl Simon, Godwin, Eryn M., Kendall, Sara, Shipman, Cassaundra, Bradford, Carol, Carey, Thomas, Haddad, Andrea, Moyer, Jeffey, Peterson, Lisa, Prince, Mark, Rozek, Laura, Wolf, Gregory, Bowman, Rayleen, Fong, Kwun M., Yang, Ian, Korst, Robert, Rathmell, W. Kimryn, Fantacone-Campbell, J. Leigh, Hooke, Jeffrey A., Kovatich, Albert J., Shriver, Craig D., DiPersio, John, Drake, Bettina, Govindan, Ramaswamy, Heath, Sharon, Ley, Timothy, Van Tine, Brian, Westervelt, Peter, Rubin, Mark A., Lee, Jung Il, Aredes, Natália D., Mariamidze, Armaz, Stuart, Joshua M., Benz, Christopher C., Laird, Peter W.·2018·Cell
DOI 10.1016/j.cell.2018.03.022

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    Chandrani Chattopadhyay, Junna Oba, Jason Roszik, Joseph R. Marszalek, Ken Chen, Yuan Qi, Karina Agda Eterovic, A. Gordon Robertson, Jared K. Burks, Tara A. McCannel et al. · 2019 · Investigative Ophthalmology & Visual Science
  43. Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy
    Anmi Jose, Gautham G. Shenoy, Gabriel Sunil Rodrigues, Naveena A. N. Kumar, Murali Munisamy, Levin Thomas, Jill Kolesar, Ganesha Rai, Praveen P. N. Rao, Mahadev Rao · 2020 · Cancers
  44. Epigenome Remodeling in Cholangiocarcinoma
    Colm J. O’Rourke, Juan F. Lafuente-Barquero, Jesper Bøje Andersen · 2019 · Trends in cancer
  45. Urothelial-to-Neural Plasticity Drives Progression to Small Cell Bladder Cancer
    Guoliang Yang, Jolanta E. Bondaruk, David E. Cogdell, Ziqiao Wang, Sangkyou Lee, June Goo Lee, Shizhen Zhang, Woonyoung Choi, Yan Wang, Yu Liang et al. · 2020 · iScience
  46. Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling
    Jin-Fen Xiao, Andrew W. Caliri, Jason E. Duex, Dan Theodorescu · 2021 · Cancers
  47. WNT signaling at the intersection between neurogenesis and brain tumorigenesis
    Maisa I. Alkailani, Mohamed Aittaleb, Fadel Tissir · 2022 · Frontiers in Molecular Neuroscience
  48. p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
    Kasumi Murai, Stefan C. Dentro, Swee Hoe Ong, Roshan K. Sood, David Fernández‐Antorán, Albert Herms, Vasiliki Kostiou, Irina Abnizova, Benjamin A. Hall, Moritz Gerstung et al. · 2022 · Nature Communications
  49. Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications
    Britta Weigelt, Antonio Marra, Pier Selenica, Eric Rios‐Doria, Amir Momeni Boroujeni, Michael F. Berger, Kanika S. Arora, David Nemirovsky, Alexia E. Iasonos, Debyani Chakravarty et al. · 2023 · Cancer Discovery
  50. Artificial intelligence in gastric cancer: applications and challenges
    Runnan Cao, Lei Tang, Mengjie Fang, Lianzhen Zhong, Siwen Wang, Lixin Gong, Jiazheng Li, Di Dong, Jie Tian · 2022 · Gastroenterology report
  51. AI in medicine: Where are we now and where are we going?
    Md Mobashir Hasan Shandhi, Jessilyn Dunn · 2022 · Cell Reports Medicine
  52. Correlation Analysis of Histopathology and Proteogenomics Data for Breast Cancer
    Xiaohui Zhan, Jun Cheng, Zhi Huang, Zhi Han, Bryan R. Helm, Xiaowen Liu, Jie Zhang, Tianfu Wang, Dong Ni, Kun Huang · 2019 · Molecular & Cellular Proteomics
  53. A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes
    Yueyuan Zheng, Guowei Huang, Tiago C. Silva, Qian Yang, Yan‐Yi Jiang, Harold Phillip Koeffler, De‐Chen Lin, Benjamin P. Berman · 2021 · Nature Communications
  54. Immune Determinants of the Association between Tumor Mutational Burden and Immunotherapy Response across Cancer Types
    Neelam Sinha, Sanju Sinha, Cristina Valero, Alejandro A. Schäffer, Kenneth Aldape, Kevin Litchfield, Timothy A Chan, Luc G T Morris, Eytan Ruppin · 2022 · Cancer Research
  55. Cholangiocarcinoma 2020: the next horizon in mechanisms and management
    Banales, Jesus M., Marin, Jose J. G., Lamarca, Angela, Rodrigues, Pedro M., Khan, Shahid A., Roberts, Lewis R., Cardinale, Vincenzo, Carpino, Guido, Andersen, Jesper B., Braconi, Chiara et al. · 2020 · Nature Reviews Gastroenterology & Hepatology
  56. SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia
    Yiliang Wei, Yu-Han Huang, Damianos S. Skopelitis, Shruti V. Iyer, Ana S.H. Costa, Zhaolin Yang, Melissa Kramer, Emmalee R. Adelman, Olaf Klingbeil, Osama E. Demerdash et al. · 2021 · Cancer Discovery
  57. DNA methylation in human diseases
    Samareh Younesian, Mohammad Hossein Mohammadi, Ommolbanin Younesian, Majid Momeny, Seyed Hamidollah Ghaffari, Davood Bashash · 2024 · Heliyon
  58. Mutational inactivation of mTORC1 repressor gene DEPDC5 in human gastrointestinal stromal tumors
    Yuzhi Pang, Feifei Xie, Hui Cao, Chun-Meng Wang, Mei-Jun Zhu, Xiaoxiao Liu, Xiaojing Lu, Tao Huang, Yan-Ying Shen, Ke Li et al. · 2019 · Proceedings of the National Academy of Sciences of the United States of America
  59. Leveraging TCGA gene expression data to build predictive models for cancer drug response
    Evan A. Clayton, Toyya A. Pujol, John F. McDonald, Peng Qiu · 2020 · BMC Bioinformatics
  60. Ultra-sensitive detection of tumor-specific mutations in saliva of patients with oral cavity squamous cell carcinoma
    Ashwini Shanmugam, A. Hariharan, R. Hasina, J. Nair, S. Katragadda, Sivaraj Irusappan, A. Ravichandran, V. Veeramachaneni, Radhakrishna Bettadapura, Muddasir Bhati et al. · 2020 · Cancer
  61. Retroviral integrations contribute to elevated host cancer rates during germline invasion
    Gayle K. McEwen, David E. Alquezar‐Planas, Anisha Dayaram, Amber Kristen Gillett, Rachael Eugenie Tarlinton, Nigel Patrick Mongan, Keith J. Chappell, Joerg Henning, Milton Tan, Peter Timms et al. · 2021 · Nature Communications
  62. Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition
    Sheng F. Cai, S. Haihua Chu, Aaron D. Goldberg, Salma Parvin, Richard P. Koche, Jacob Lowell Glass, Eytan M. Stein, Martin S. Tallman, Filiz Şen, Christopher A. Famulare et al. · 2020 · Cancer Discovery
  63. Quantum processor-inspired machine learning in the biomedical sciences
    Richard Y. Li, Sharvari Gujja, Sweta R. Bajaj, Omar Gamel, Nicholas A. Cilfone, Jeffrey R. Gulcher, Daniel A. Lidar, Thomas W. Chittenden · 2021 · Patterns
  64. The role of chromatin remodeler SMARCA4/BRG1 in brain cancers: a potential therapeutic target
    Sophie M. Navickas, Katherine A. Giles, Kate H. Brettingham‐Moore, Phillippa C. Taberlay · 2023 · Oncogene
  65. Integrated multi-omics analysis reveals the molecular interplay between circadian clocks and cancer pathogenesis
    Andy Pérez‐Villa, Gabriela Echeverría‐Garcés, María José Ramos-Medina, Lavanya Prathap, Mayra Fernanda Martínez-López, David Ramírez-Sánchez, Jennyfer M. Garcí­a-Cárdenas, Isaac Armendáriz‐Castillo, Santiago Xavier Guerrero, Clara Paz et al. · 2023 · Scientific Reports
  66. ZEB2 is a master switch controlling the tumor-associated macrophage program
    Fadi Sheban, Truong San Phan, Ken Xie, Florian Ingelfinger, Chamutal Gur, Yuval Shapir Itai, Ronnie Blecher‐Gonen, Chunsong Yu, Roberto Avellino, Paulina Chalan et al. · 2025 · Cancer Cell
  67. The pan-cancer landscape of prognostic germline variants in 10,582 patients
    Ajay Chatrath, Róża K. Przanowska, Shashi Kiran, Zhangli Su, Shekhar Saha, Briana Wilson, Takaaki Tsunematsu, Ji‐Hye Ahn, Kyung Yong Lee, Teressa Paulsen et al. · 2020 · Genome Medicine
  68. Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis
    Stephanie Taha‐Mehlitz, Gaia Bianco, Mairene Coto‐Llerena, Venkatesh Kancherla, Glenn R. Bantug, John Gallon, Caner Ercan, Federica Panebianco, Serenella Eppenberger‐Castori, Marco von Strauss et al. · 2021 · Theranostics
  69. Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators
    Jiakai Hou, Yunfei Wang, Leilei Shi, Yuan Chen, Chunyu Xu, Arash Saeedi, Ke Pan, Ritu Bohat, Nicholas A. Egan, Jodi A. McKenzie et al. · 2021 · Journal for ImmunoTherapy of Cancer
  70. DNA Methylation Signatures Reveal the Diversity of Processes Remodeling Hepatocellular Carcinoma Methylomes
    Léa Meunier, Théo Z. Hirsch, Stefano Caruso, Sandrine Imbeaud, Quentin Bayard, Amélie Roehrig, Gabrielle Couchy, Jean‐Charles Nault, Josep Maria Llovet, Jean‐Frédéric Blanc et al. · 2021 · Hepatology
  71. Non-invasive lung cancer diagnosis and prognosis based on multi-analyte liquid biopsy
    Kezhong Chen, Jianlong Sun, Heng Zhao, Ruijingfang Jiang, Jianchao Zheng, Zhilong Li, Jiaxi Peng, Haifeng Shen, Kai Zhang, Jin Zhao et al. · 2021 · Molecular Cancer
  72. Targeting Chromosomal Architectural HMGB Proteins Could Be the Next Frontier in Cancer Therapy
    Anirban Mukherjee, Karen M. Vásquez · 2020 · Cancer Research
  73. Genomic Landscape and Clinical Utility in Korean Advanced Pan-Cancer Patients from Prospective Clinical Sequencing: K-MASTER Program
    Kyong Hwa Park, Jung Yoon Choi, Ah-Reum Lim, Ju Won Kim, Yoon Ji Choi, Soo Hyun Lee, Jae Sook Sung, Hee-Joon Chung, Byunghyun Jang, Dayoung Yoon et al. · 2021 · Cancer Discovery
  74. The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer
    Nesrin M. Hasan, Nita Ahuja · 2019 · Cancers
  75. HPV33+ HNSCC is associated with poor prognosis and has unique genomic and immunologic landscapes
    Kate Chatfield‐Reed, Shanying Gui, Wendi Quinn O’Neill, Theodoros Nicholas Teknos, Quintin Pan · 2019 · Oral Oncology
  76. Human CtIP: A ‘double agent’ in DNA repair and tumorigenesis
    Nour L. Mozaffari, Fabio Pagliarulo, Alessandro A. Sartori · 2020 · Seminars in Cell and Developmental Biology
  77. Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer
    Kanchan Singh, Melissa A. Pruski, Rachael Bland, Mamoun Younes, Sushovan Guha, Nirav C Thosani, Anirban Maitra, Brooks D. Cash, Florencia M. McAllister, Craig D. Logsdon et al. · 2020 · Laboratory Investigation
  78. Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis
    Jake J. Reske, Mike R. Wilson, Jeanne Holladay, Rebecca A. Siwicki, Hilary J. Skalski, Shannon K. Harkins, Marie Adams, John Ian Risinger, Galen H. Hostetter, Ken Yu Lin et al. · 2021 · PLoS Genetics
  79. A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death
    Ceder, Sophia, Eriksson, Sofi E, Cheteh, Emarndeena H, Dawar, Swati, Corrales Benitez, Mariana, Bykov, Vladimir J N, Fujihara, Kenji M, Grandin, Mélodie, Li, Xiaodun, Ramm, Susanne et al. · 2021 · EMBO Molecular Medicine
  80. High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer
    Jeong Eun Kim, Jaeyong Choi, Chang-Ohk Sung, Yong Sang Hong, Sun Young Kim, Hyun-Jung Lee, Jong‐Il Kim, Jong‐Il Kim · 2021 · Experimental & Molecular Medicine
  81. Diagnostic classification of childhood cancer using multiscale transcriptomics
    Federico Comitani, Joshua O. Nash, Sarah Cohen‐Gogo, Astra I. Chang, Timmy T. Wen, Anant Maheshwari, Bipasha Goyal, Earvin S. Tio, Kevin Tabatabaei, Chelsea Mayoh et al. · 2023 · Nature Medicine
  82. IL‐1β Is an Androgen‐Responsive Target in Macrophages for Immunotherapy of Prostate Cancer
    Deng Wang, Chaping Cheng, Xinyu Chen, Jinming Wang, Kaiyuan Liu, Na Jing, Penghui Xu, Xialian Xi, Yujiao Sun, Zhongzhong Ji et al. · 2023 · Advanced Science
  83. WWOX, the FRA16D gene: A target of and a contributor to genomic instability
    Tabish Hussain, Bin Liu, Morgan S. Schrock, Terence Marques Williams, C. Marcelo Aldaz · 2018 · Genes Chromosomes and Cancer
  84. DeePathology: Deep Multi-Task Learning for Inferring Molecular Pathology from Cancer Transcriptome
    Behrooz Azarkhalili, Ali Saberi, Hamidreza Chitsaz, Ali Sharifi‐Zarchi · 2019 · Scientific Reports
  85. MicroRNA-Mediated Metabolic Reprograming in Renal Cancer
    Joanna Bogusławska, Piotr Popławski, Saleh Alseekh, Marta Koblowska, Roksana Iwanicka‐Nowicka, Beata Rybicka, Hanna Kędzierska, Katarzyna Głuchowska, Karolina Hanusek, Zbigniew Tański et al. · 2019 · Cancers
  86. Integrated characterisation of cancer genes identifies key molecular biomarkers in stomach adenocarcinoma
    Haifeng Wang, Liyijing Shen, Yaoqing Li, Jieqing Lv · 2020 · Journal of Clinical Pathology
  87. VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
    Luis Francisco Lorenzo‐Martín, Natalia Fernández-Parejo, Mauricio Menacho-Márquez, Sonia Rodríguez‐Fdez, Javier Robles‐Valero, Sonia Zumalave, Salvatore Fabbiano, Gloria Pascual, Juana Maria Garcia-Pedrero, Antonio Abad et al. · 2020 · Nature Communications
  88. Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600E/K mutated malignant melanomas
    Sebastian Klein, Cornelia Mauch, Klaus Brinker, Ka‐Won Noh, Sonja Knez, Reinhard Büttner, Alexander Quaas, Doris Helbig · 2021 · Scientific Reports
  89. Integrative cBioPortal Analysis Revealed Molecular Mechanisms That Regulate EGFR-PI3K-AKT-mTOR Pathway in Diffuse Gliomas of the Brain
    Petar Brlek, Anja Kafka, Anja Bukovac, Nives Pećina‐Šlaus · 2021 · Cancers
  90. BCL9 regulates CD226 and CD96 checkpoints in CD8+ T cells to improve PD-1 response in cancer
    Mei Feng, Zhongen Wu, Yan Zhou, Zhuang Wei, Enming Tian, Shenglin Mei, Yuanyuan Zhu, Chenglong Liu, Fenglian He, Huiyu Li et al. · 2021 · Signal Transduction and Targeted Therapy
  91. SAMHD1 in cancer: curse or cure?
    Kerstin Schott, Catharina Majer, Alla Bulashevska, Liam Harold Childs, Mirko H. H. Schmidt, Krishnaraj Rajalingam, Markus Munder, Renate König · 2021 · Journal of Molecular Medicine
  92. ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer
    Johnson, Radia M., Qu, Xueping, Lin, Chu-Fang, Huw, Ling-Yuh, Venkatanarayan, Avinashnarayan, Sokol, Ethan, Ou, Fang-Shu, Ihuegbu, Nnamdi, Zill, Oliver A., Kabbarah, Omar et al. · 2022 · Nature Communications
  93. A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
    Stephen Tang, Vidyalakshmi Sethunath, Nebiyou Y. Metaferia, Marina F. Nogueira, Daniel S. Gallant, Emma R. Garner, Lauren A. Lairson, Christopher M. Penney, Jiao Li, Maya K. Gelbard et al. · 2022 · Cell Reports
  94. MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC
    Derek A. Franklin, Joe T. Sharick, Paula I. González Ericsson, Violeta M. Sanchez, Phillip T. Dean, Susan R. Opalenik, Stefano Cairo, Jean‐Gabriel Judde, Michael T. Lewis, Jenny C. Chang et al. · 2020 · JCI Insight
  95. Pan-cancer landscape of the RUNX protein family reveals their potential as carcinogenic biomarkers and the mechanisms underlying their action
    Shen Pan, Siyu Sun, Bitian Liu, Yang Hou · 2022 · Journal of Translational Internal Medicine
  96. The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity
    Mustafa Sibai, Sergi Cervilla, Daniela Grases, Eva Musulén, Rossana Lazcano, Chia-Kuei Mo, Verónica Dávalos, Arola Fortian, Adrià Bernat‐Peguera, Margarita Romeo et al. · 2025 · Cell Reports
  97. Improving prediction performance of colon cancer prognosis based on the integration of clinical and multi-omics data
    Danyang Tong, Yu Tian, Tianshu Zhou, Qiancheng Ye, Jun Li, Kefeng Ding, Jingsong Li · 2020 · BMC Medical Informatics and Decision Making
  98. Common germline-somatic variant interactions in advanced urothelial cancer
    Aram Vosoughi, Tuo Zhang, Kyrillus Samaan Shohdy, Panagiotis J. Vlachostergios, David C. Wilkes, Bhavneet Bhinder, Scott T. Tagawa, David M. Nanus, Ana M. Molina, Himisha Beltran et al. · 2020 · Nature Communications
  99. Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers
    Jonas Béal, Lorenzo Pantolini, Vincent Noël, Emmanuel Barillot, Laurence Calzone · 2021 · PLoS Computational Biology
  100. Identifying Molecular Biomarkers for Diseases With Machine Learning Based on Integrative Omics
    Kai Shi, Wei Jen Lin, Xing‐Ming Zhao · 2020 · IEEE Transactions on Computational Biology and Bioinformatics