Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut

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Sleep Drives Metabolite Clearance from the Adult Brain

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Reactive Oxygen Species in Inflammation and Tissue Injury

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ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis

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ROS Are Good

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Individual Ants Do Not Show Activity-Rest Rhythms in Nest Conditions

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Pyocyanin Modulates Gastrointestinal Transformation and Microbiota

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Artificial cells from microfluidic electrospray for reactive oxygen species scavenging

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A gut-secreted peptide controls arousability through modulation of dopaminergic neurons in the brainPreprint

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Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

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Ubiquitin proteasome system in circadian rhythm and sleep homeostasis: Lessons from Drosophila

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Chlorella pyrenoidosa polysaccharides supplementation increases Drosophila melanogaster longevity at high temperature

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Inhibiting mechanism of Pseudomonas aeruginosa biofilm formation - An innovational reagent of plasma-activated lactic acid

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The association between sleep quality and telomere attrition: A systematic review and meta-analysis comprising 400,212 participants

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Transcriptional dynamics of sleep deprivation and subsequent recovery sleep in the male mouse cortex

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Fermented Gastrodia elata Bl. Intervenes gut microbiota and amino acid metabolism in zebrafish to promote 5-HT homeostasis against sleep disturbances

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Age mosaic of gut epithelial cells prevents aging

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Brainstem circuit for sickness-induced sleep

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Neocortical long-range inhibition promotes cortical synchrony and sleep

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Do Sleep Disturbances have a Dual Effect on Alzheimer’s Disease?

Arjmandi-Rad, S., Ebrahimnejad, M., Zarrindast, M., & Vaseghi, S. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01228-1 · Cited by 11

Modulation and neural correlates of postmating sleep plasticity in Drosophila females

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Gallic Acid Ameliorates Cognitive Impairment Caused by Sleep Deprivation through Antioxidant Effect

Pang, X., Xu, Y., Xie, S., Zhang, T., Cong, L., Qi, Y., Liu, L., Li, Q., Mo, M., Wang, G., et al. (2023) · Experimental Neurobiology · doi:10.5607/en23015 · Cited by 10

Identification of ultrastructural signatures of sleep and wake in the fly brain

Flores, C. C., Loschky, S. S., Marshall, W., Spano, G. M., Cenere, M. M., Tononi, G., & Cirelli, C. (2021) · SLEEP · doi:10.1093/sleep/zsab235 · Cited by 10

Sleep Fragmentation Accelerates Carcinogenesis in a Chemical-Induced Colon Cancer Model

Lee, D.-B., An, S.-Y., Pyo, S. S., Kim, J., Kim, S. W., & Yoon, D. W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054547 · Cited by 10

The effect of explicit and implicit online self-compassion interventions on sleep quality among Chinese adults: A longitudinal and diary study

Sheng, H., Wang, R., & Liu, C. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1062148 · Cited by 11

Differences in intestinal motility during different sleep stages based on long-term bowel sounds

Wang, G., Chen, Y., Liu, H., Yu, X., Han, Y., Wang, W., & Kang, H. (2023) · BioMedical Engineering OnLine · doi:10.1186/s12938-023-01166-z · Cited by 9

Does glial lipid dysregulation alter sleep in Alzheimer’s and Parkinson’s disease?

Goodman, L. D., Moulton, M. J., Lin, G., & Bellen, H. J. (2024) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2024.04.010 · Cited by 9

Sleep Deficiency and Cardiometabolic Disease

Killick, R., Stranks, L., & Hoyos, C. M. (2024) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2024.07.011 · Cited by 10

Intestinal stearoyl-coenzyme A desaturase-inhibition improves obesity-associated metabolic disorders

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The neural architecture of sleep regulation – insights from Drosophila

Suárez-Grimalt, R., & Raccuglia, D. (2021) · e-Neuroforum · doi:10.1515/nf-2021-0018 · Cited by 9

Estimation of gingival crevicular fluid oxidative stress markers in school-aged children and teenagers with insufficient sleep

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The endogenous antioxidant ability of royal jelly in Drosophila is independent of Keap1/Nrf2 by activating oxidoreductase activity

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Photomodulatory effects in the hypothalamus of sleep-deprived young and aged rats

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Prevalence and related factors of sleep quality among Chinese undergraduates in Jiangsu Province: multiple models' analysis

Hu, B., Shen, W., Wang, Y., Wu, Q., Li, J., Xu, X., Han, Y., Xiao, L., & Yin, D. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1343186 · Cited by 10

Movement as a Positive Modulator of Aging

Bičı́ková, M., Máčová, L., Jandová, D., Třískala, Z., & Hill, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126278 · Cited by 10

Cancer as a tool for preclinical psychoneuroimmunology

Borniger, J. C. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100351 · Cited by 10

Reactive Species-Activatable AIEgens for Biomedical Applications

Kang, X., Li, Y., Yin, S., Li, W., & Qi, J. (2022) · Biosensors · doi:10.3390/bios12080646 · Cited by 9

Sustained microglial activation and accelerated elimination of dendritic spines during acute sleep deprivation and restoration

Liu, J., Xu, Y., Ji, Y., Li, K., Wang, S., Zhao, B., Ruan, J., Foulkes, N. S., Zhang, S., & Zhao, H. (2023) · The Innovation Life · doi:10.59717/j.xinn-life.2023.100037 · Cited by 8

Excess dietary sugar impairs Drosophila adult stem cells via elevated reactive oxygen species-induced JNK signaling

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Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism

Bose, K., Agrawal, R., Sairam, T., Mil, J., Butler, M. P., & Dhandapany, P. S. (2024) · iScience · doi:10.1016/j.isci.2024.109075 · Cited by 9

Glucose competition between endothelial cells in the blood-spinal cord barrier and infiltrating regulatory T cells is linked to sleep restriction-induced hyperalgesia

Huang, Y., Xu, R. D., Liu, Q., Zhang, X., Mao, Y., Yang, Y., Gu, X., Liu, Y., & Ma, Z. (2024) · BMC Medicine · doi:10.1186/s12916-024-03413-z · Cited by 8

Antagonistic interaction between caffeine and ketamine in zebrafish: Implications for aquatic toxicity

Wang, Z., Xu, J., & Du, W. (2024) · Environmental Science and Ecotechnology · doi:10.1016/j.ese.2024.100437 · Cited by 8

Natural flavonoid glycosides Chrysosplenosides I & A rejuvenate intestinal stem cell aging via activation of PPARγ signaling

Ye, J., Yan, L., Yu, Y., Fu, F., Lu, Y., Fan, X., Zhou, J., Zhu, Y., Liu, X., Ren, G., et al. (2024) · Life Medicine · doi:10.1093/lifemedi/lnae025 · Cited by 8

Ferulic acid reduces gut redox potential and alleviates chronic Mg-induced diarrhea by modulating gut microbiota and metabolites

Feng, N., You, J., Xu, R., Chen, L., Wang, D., Li, L., Su, Y., & Feng, X. (2024) · Animal Advances · doi:10.48130/animadv-0024-0004 · Cited by 8

Jujuboside A improves insomnia by maintaining mitochondrial homeostasis in prefrontal neurons

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Progressive Blood–Brain Barrier Disruption in Sleep-Restricted Young Mice: Cellular Senescence and Neuroinflammation Crosstalk

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An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

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Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague–Dawley rats

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Sleep deprivation induces corneal endothelial dysfunction by downregulating Bmal1

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Lacticaseibacillus rhamnosus GG alleviates sleep deprivation-induced intestinal barrier dysfunction and neuroinflammation in mice

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Quiescence Enhances Survival during Viral Infection inCaenorhabditis elegans

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Chronic Jet Lag Disrupts Circadian Rhythms and Induces Hyperproliferation in Murine Lacrimal Glands via ROS Accumulation

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Both increased and decreased sleep duration over time are associated with subsequent cancer development

Fukui, S., Shimbo, T., & Kobayashi, D. (2021) · Sleep And Breathing · doi:10.1007/s11325-021-02517-7 · Cited by 8

Sleep Modulates Alcohol Toxicity in Drosophila

Nobrega, A. K. D., Noakes, E. J., Storch, N. A., Mellers, A. P., & Lyons, L. C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012091 · Cited by 7

Amelioration of pain and anxiety in sleep-deprived rats by intra-amygdala injection of cinnamaldehyde

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Effects of Dendropanax morbiferus Leaf Extract on Sleep Parameters in Invertebrate and Vertebrate Models

Ko, K., Ahn, Y., Cheon, G. Y., Suh, H. J., Cho, Y. J., Park, S., & Hong, K. (2023) · Antioxidants · doi:10.3390/antiox12101890 · Cited by 7

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis

Zheng, Z.-L., Zheng, Q.-F., Wang, L., & Liu, Y. (2024) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i2.100589 · Cited by 9

Alzheimer's disease and gut-brain axis: Drosophila melanogaster as a model

Alves, S. D. M., Lisboa‐Filho, P. N., Vieira, C. L. Z., & Piacenti‐Silva, M. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1543826 · Cited by 8

Enhanced memory despite severe sleep loss in Drosophila insomniac mutants

Huang, S., Piao, C., Zhao, Z., Beuschel, C. B., Turrel, O., Toppe, D., & Sigrist, S. J. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003076 · Cited by 6

Gender correlation between sleep duration and risk of coronary heart disease: a systematic review and meta-analysis

Li, C., Luo, S.-X., Liang, T.-W., Song, D., & Fu, J. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1452006 · Cited by 8

Unraveling the nexus: Sleep's role in ferroptosis and health

Zhao, P.-C., Wu, Z., Zhu, Y., Gong, T., & Zhu, Z. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111412 · Cited by 7

Investigating the immunomodulatory effects of honeybee venom peptide apamin in Drosophila platforms

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Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands

Zhang, W., Qi, D., Pei, X., Lu, D., Ba, M., Xuan, S., Huang, D., Yang, T., Yang, J., Li, Z., et al. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03630-5 · Cited by 7

Optimization of extraction methods, component identification of bound polyphenols from sea-buckthorn pomace, and its ameliorative effects on oxidative stress in sleep-deprived mice

Peng, J., Li, X., Yuan, M., Tang, Y., Qiao, T., Li, J., Yu, H., Zhang, M., Li, X., & Lan, Y. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.147018 · Cited by 8

Vitamin D3 Improves Hypothalamic–Pituitary–Adrenal Axis Function, Immunological Responses, and Gut Dysbiosis in Sleep Desynchrony

Wu, C. W., Huang, Y., Xu, J., Fan, H., Zeng, J., Yang, Y. S. H., & Tung, Y. (2025) · Brain and Behavior · doi:10.1002/brb3.71084 · Cited by 9

Sleep regulation in Drosophila: a review of neural circuits and genetics

Zhao, Y., Zhang, K., Bian, H., Ma, X., Wang, S., Wang, Y., Yu, S., & Huang, L. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1750211 · Cited by 8

Photoactivatable aggregation‐induced emission luminogens based on photodehydrogenation reactions for biomedical applications

You, Y., Tang, C., Lin, S., Zeng, D., Cong, Y., Wang, D., & Chen, X. (2023) · Luminescence · doi:10.1002/bio.4645 · Cited by 7

Shared genetic architecture and causal relationship between sleep behaviors and lifespan

Wu, Y., Zhang, C., Liu, X., Wang, L., Li, M., Li, Y., & Xiao, X. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02826-x · Cited by 7

Therapeutic potential of Astragalus membranaceus — Pueraria lobata decoction for the treatment of chemotherapy bowel injury

Wang, Y., Qin, Y., Kang, Q., Wang, H., Zhou, S., Wu, Y., Liu, Y., Su, Y., Guo, Y., Xiu, M., et al. (2024) · The FASEB Journal · doi:10.1096/fj.202401677r · Cited by 7

Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus

Rubinstein, L., Kiffer, F. C., Puukila, S., Lowe, M. G., Goo, B., Luthens, A., Schreurs, A., Torres, S. M., Steczina, S., Tahimic, C. G. T., et al. (2022) · Life · doi:10.3390/life12111838 · Cited by 7

Facile synthesis of Cu N-lauroyl sarcosinate nanozymes with laccase-mimicking activity and identification of toxicity effects for C. elegans

Meng, F., Ma, G., Qiu, J., Fu, Z., Yan, J., & Wang, L. (2022) · RSC Advances · doi:10.1039/d2ra03759a · Cited by 7

Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin

Liu, Z., He, Y., Wang, Y., Kefeng, R., Xia, P., Xie, B., & Tian, W. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.117851 · Cited by 6

Rest, Repair, Repeat: The Complex Relationship of Autophagy and Sleep

Ullern, H., Schnur, P., Boccara, C. N., & Knævelsrud, H. (2025) · Journal of Molecular Biology · doi:10.1016/j.jmb.2025.169227 · Cited by 8

Ellagic acid alleviates sepsis-induced intestinal injury by modulating gut microbiota and NF-κB-mediated MLCK/MLC signaling pathway

Liu, K., Sun, H., Wang, H., Zheng, J., Wang, X., Wang, X., Hou, Y., Ye, Q., & Li, J. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.108026 · Cited by 6

Exploring the Impact and Mechanisms of Coffee and Its Active Ingredients on Depression, Anxiety, and Sleep Disorders

Shi, Z., Luan, J., Zhang, Y., Wang, G., Mei, C., Chen, L., Zhou, W., Xiong, C., Huang, T., Zhan, J., et al. (2025) · Nutrients · doi:10.3390/nu17193037 · Cited by 9

IMD signaling in the gut and the brain modulates Amyloid-beta-induced deficits in Drosophila

Hsieh, T., & Chiang, H. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122118 · Cited by 6

The effects of ambient temperature and feeding regimens on cecum bacteria composition and circadian rhythm in growing rabbits

He, S., Zhang, K., Jin, Q.-Y., Wang, Q., Huang, J., Li, J.-J., Guo, Y., Liu, P., Zhong-ying, L., Liu, D., et al. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1344992 · Cited by 6

Sleep deprivation boosts O2·− levels in the brains of mice as visualized by a Golgi apparatus–targeted ratiometric fluorescence nanosensor

Song, W., Yao, C., Lu, Y., Qian, Q., Wu, J., Shi, W., Li, H., Huang, H., Song, W., & Song, W. (2024) · Microchimica Acta · doi:10.1007/s00604-024-06352-x · Cited by 6

Acute 2-phenyl-3-(phenylselanyl)benzofuran treatment reverses the neurobehavioral alterations induced by sleep deprivation in mice

Gonçalves, L., Rusch, G., Alves, A. G., Krüger, L. D., Paim, M. P., Martins, C. C., da Motta, K. P., Neto, J. S. S., Luchese, C., Wilhelm, E. A., et al. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116339 · Cited by 6

Age and objectively measured sleep: investigating associations and interactions by sex and race in middle-aged and older adults

He, L., Rabinowitz, J. A., An, Y., Jackson, C. L., Hellinger, R., Wanigatunga, S., Schrack, J. A., Ferrucci, L., Simonsick, E. M., Koehler, K. A., et al. (2024) · SLEEP Advances · doi:10.1093/sleepadvances/zpae045 · Cited by 6

Sleep induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila

Inami, S., & Koh, K. (2024) · SLEEP · doi:10.1093/sleep/zsae226 · Cited by 9

The interaction between sleep patterns and oxidative balance scores on the risk of cognitive function decline: Results from the national health and nutrition examination survey 2011–2014

Lou, T., Zhao, Z., Du, H., Zhang, J., Tian, N., Wang, M., & Li, Q. (2024) · PLoS ONE · doi:10.1371/journal.pone.0313784 · Cited by 6

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Melnattur, K. V., Morgan, E. P., Duong, V., Kalra, A., & Shaw, P. J. (2020) · Journal of Visualized Experiments · doi:10.3791/62105 · Cited by 10

Metabolic fingerprints of fear memory consolidation during sleep

Koyanagi, I., Sonomura, K., Naoi, T., Ohnishi, T., Kaneko, N., Sawamoto, K., Sato, T., & Sakaguchi, M. (2021) · Molecular Brain · doi:10.1186/s13041-021-00733-6 · Cited by 6

PARP1 inhibition enhances reactive oxygen species on gut microbiota

Zhuang, Y., Wang, H., Ding, J., Zhang, X., Liu, X., Zhang, S., Xing, X., Kaudimba, K. K., He, M., Zhang, S., et al. (2022) · Journal of Cellular Physiology · doi:10.1002/jcp.30861 · Cited by 5

Impact of Sleep on Autophagy and Neurodegenerative Disease: Sleeping Your Mind Clear

Deutsch, S., & Malik, B. R. (2022) · Archives of Molecular Biology and Genetics · doi:10.33696/genetics.1.007 · Cited by 5

Gut redox potential affects host susceptibility to pathogen infection

Qi, X., Zhang, Y., Wang, G., & Ling, F. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.739661 · Cited by 7

Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila

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