5-HT1A receptor-regulated signal transduction pathways in brain

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., & Greenberg, M. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80595-4 · Cited by 5,594

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M., & Hemmings, B. A. (1995) · Nature · doi:10.1038/378785a0 · Cited by 5,244

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

da Luz, A. C. D. D. S., Dias, G. P., Bevilaqua, M. C. D. N., Cocks, G. D., Gardino, P. F., Thuret, S., & Nardi, A. E. (2013) · Neuropsychobiology · doi:10.1159/000353269 · Cited by 4,015

A molecular mechanism for the effect of lithium on development.

Klein, P. S., & Melton, D. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.16.8455 · Cited by 2,334

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Bonni, A., Brunet, A., West, A. E., Datta, S. R., Takasu, M. A., & Greenberg, M. E. (1999) · Science · doi:10.1126/science.286.5443.1358 · Cited by 1,908

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

Pazos, Á., & Palacios, J. M. (1985) · Brain Research · doi:10.1016/0006-8993(85)90856-x · Cited by 1,855

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

Dérijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R. J., & Davis, R. J. (1995) · Science · doi:10.1126/science.7839144 · Cited by 1,555

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

Yao, R., & Cooper, G. M. (1995) · Science · doi:10.1126/science.7701324 · Cited by 1,393

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

Xing, J. W., Ginty, D. D., & Greenberg, M. E. (1996) · Science · doi:10.1126/science.273.5277.959 · Cited by 1,246

Sevoflurane prevents stroke‐induced depressive and anxiety behaviors by promoting cannabinoid receptor subtype I‐dependent interaction between β‐arrestin 2 and extracellular signal‐regulated kinases 1/2 in the rat hippocampus

Zhang, H., Li, L., Sun, Y., Zhang, X., Zhang, Y., Xu, S., Zhao, P., & Liu, T. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13613 · Cited by 21

A Comprehensive Review of Nutritional Influences on the Serotonergic System

Tang, J., Krushelnycky, L., Shaqo, A., & Cho, C. E. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100524 · Cited by 21

Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice

Nogueira, M., Golbert, D. C. F., de Menezes, R. S. T., de Almeida, R. N., Coelho, N. L. G., Siroky, A. N., Lima, T. Z., Maia, H., Leão, K. E., & Leão, R. N. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02655-w · Cited by 22

5-Hydroxytryptamine–Mediated Neurotransmission Modulates Spontaneous and Vagal-Evoked Glutamate Release in the Nucleus of the Solitary Tract Effect of Uptake Blockade

Hosford, P. S., Mifflin, S., & Ramage, A. G. (2014) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.113.211334 · Cited by 20

Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT1A and 5-HT7 G protein-coupled receptor affinity, 3D-QSAR and molecular modeling

Perry, C. K., Casey, A. B., Felsing, D. E., Vemula, R., Zaka, M., Herrington, N. B., Cui, M., Kellogg, G. E., Canal, C. E., & Booth, R. G. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.115262 · Cited by 20

Curated Database and Preliminary AutoML QSAR Model for 5-HT1A Receptor

Łapińska, N., Pacławski, A., Szlęk, J., & Mendyk, A. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101711 · Cited by 20

Contribution of Axon Initial Segment Structure and Channels to Brain Pathology

Garrido, J. J. (2023) · Cells · doi:10.3390/cells12081210 · Cited by 19

Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia

Tirgar, F., Rezayof, A., & Zarrindast, M. R. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.07.014 · Cited by 19

Computational modeling of spike generation in serotonergic neurons of the dorsal raphe nucleus

Tuckwell, H. C., & Penington, N. J. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.04.001 · Cited by 19

Serotonin Signaling Trough Prelimbic 5-HT1A Receptors Modulates CSDS-Induced Behavioral Changes in Adult Female Voles

Wang, L., Zhu, Z., Hou, W., Zhang, X., He, Z., Yuan, W., Yang, Y., Zhang, S., Jia, R., & Tai, F. (2018) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyy093 · Cited by 19

New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation

Chłoń‐Rzepa, G., Żmudzki, P., Satała, G., Duszyńska, B., Partyka, A., Wróbel‐Biedrawa, D., Jastrzębska‐Więsek, M., Wesołowska, A., Bojarski, A. J., Pawłowski, M., et al. (2013) · Pharmacological Reports · doi:10.1016/s1734-1140(13)70960-5 · Cited by 18

Functional neuroanatomy of monoaminergic systems in the basolateral nuclear complex of the amygdala: Neuronal targets, receptors, and circuits

McDonald, A. J. (2023) · Journal of Neuroscience Research · doi:10.1002/jnr.25201 · Cited by 16

Protection of p-Coumaric acid against chronic stress-induced neurobehavioral deficits in mice via activating the PKA-CREB-BDNF pathway

Cao, Y., Chen, H. L., Tan, Y., Yu, X., Xiao, C., Li, Y. Q., Reilly, J., He, Z., & Shu, X. (2023) · Physiology & Behavior · doi:10.1016/j.physbeh.2023.114415 · Cited by 17

The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression

Li, X., Li, J., Huang, Y., Gong, Q., Fu, Y., Xu, Y., Huang, J., You, H., Zhang, D., Zhang, D., et al. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.114045 · Cited by 16

Cellular profile of the dorsal raphe lateral wing sub-region: Relationship to the lateral dorsal tegmental nucleus

Vasudeva, R. K., & Waterhouse, B. D. (2014) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2014.03.001 · Cited by 17

Effect of Dopaminergic D1 Receptors on Plasticity Is Dependent of Serotoninergic 5-HT1A Receptors in L5-Pyramidal Neurons of the Prefrontal Cortex

Meunier, C. N. J., Callebert, J., Cancela, J., & Fossier, P. (2015) · PLoS ONE · doi:10.1371/journal.pone.0120286 · Cited by 17

A Shift in the Activation of Serotonergic and Non-serotonergic Neurons in the Dorsal Raphe Lateral Wings Subnucleus Underlies the Panicolytic-Like Effect of Fluoxetine in Rats

Vilela‐Costa, H. H., Spiacci, A., Bissolli, I. G., & Zangrossi, H. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1536-z · Cited by 16

Two for the Price of One

Stewart, A., Maity, B., & Fisher, R. A. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.03.001 · Cited by 16

Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices

Mendiguren, A., Aostri, E., Alberdi, E. M., Pérez‐Samartín, A., & Pineda, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.956886 · Cited by 13

Activation of 5-HT1A Receptors Normalizes the Overexpression of Presynaptic 5-HT1A Receptors and Alleviates Diabetic Neuropathic Pain

Munawar, N., Bitar, M. S., & Masocha, W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814334 · Cited by 15

Effects of the Serotonin 5-HT1A Receptor Biased Agonists, F13714 and F15599, on Striatal Neurotransmitter Levels Following l-DOPA Administration in Hemi-Parkinsonian Rats

Newman‐Tancredi, A., Varney, M. A., & McCreary, A. C. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2514-y · Cited by 15

5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression

Ambrogini, P., Lattanzi, D., Pagliarini, M., Palma, M. D., Sartini, S., Cuppini, R., Fuxé, K., & Borroto‐Escuela, D. O. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087467 · Cited by 14

Targeting 5-Hydroxytryptamine Receptor 1A in the Portal Vein to Decrease Portal Hypertension

Zhu, C., Liu, S., Wang, K.-Q., Xiong, H.-L., Aristu-Zabalza, P., Boyer‐Díaz, Z., Feng, J.-F., Song, S., Luo, C., Chen, W., et al. (2024) · Gastroenterology · doi:10.1053/j.gastro.2024.06.007 · Cited by 14

Serotonin Modulation of Dorsoventral Hippocampus in Physiology and Schizophrenia

Kandilakis, C. L., & Papatheodoropoulos, C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157253 · Cited by 14

Immunoglobulin A Autoreactivity toward Brain Enriched and Apoptosis-Regulating Proteins in Saliva of Athletes after Acute Concussion and Subconcussive Impacts

Pin, E., Petricoin, E. F., Cortés, N., Bowman, T. G., Andersson, E., Uhlén, M., Nilsson, P., & Caswell, S. V. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2020.7375 · Cited by 15

Gα Protein Signaling Bias at Serotonin 1A Receptor

Alabdali, R., Franchini, L., & Orlandi, C. (2023) · Molecular Pharmacology · doi:10.1124/molpharm.123.000722 · Cited by 11

The role of brain serotonin signaling in excessive alcohol consumption and withdrawal: A call for more research in females

Castle, M., & Flanigan, M. E. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100618 · Cited by 13

Lack of GSK3β activation and modulation of synaptic plasticity by dopamine in 5-HT1A-receptor KO mice

Meunier, C. N. J., Cancela, J., & Fossier, P. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.09.025 · Cited by 13

Preclinical characterization of ACH-000029, a novel anxiolytic compound acting on serotonergic and alpha-adrenergic receptors

de Azevedo, H. F. Z., Ferreira, M. A., Costa, R. W., Russo, V., Russo, E., Mascarello, A., & Guimarães, C. R. W. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109707 · Cited by 13

Serotonin 1A receptor inhibits the status epilepticus induced by lithium-pilocarpine in rats

Yang, Y., Guo, Y. C., Kuang, Y., Wang, S., Jiang, Y., Ding, Y., Wang, S., & Ding, M. (2014) · Neuroscience Bulletin · doi:10.1007/s12264-013-1396-x · Cited by 13

Spatial memory alterations by activation of septal 5HT1A receptors: no implication of cholinergic septohippocampal neurons

Koenig, J., Lecourtier, L., Cosquer, B., Pereira, P. M., & Cassel, J. (2010) · Psychopharmacology · doi:10.1007/s00213-010-2049-7 · Cited by 13

Serotonin 5-HT(1A) receptor binding sites in the brain of the pigeon (Columba livia).

Herold, C., Palomero-Gallagher, N., Güntürkün, O., & Zilles, K. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2011.10.050 · Cited by 13

Aminoalkyl Derivatives of 8‐Alkoxypurine‐2,6‐diones: Multifunctional 5‐HT1A/5‐HT7 Receptor Ligands and PDE Inhibitors with Antidepressant Activity

Chłoń‐Rzepa, G., Zagórska, A., Żmudzki, P., Bucki, A., Kołaczkowski, M., Partyka, A., Wesołowska, A., Kazek, G., Głuch‐Lutwin, M., Siwek, A., et al. (2016) · Archiv der Pharmazie · doi:10.1002/ardp.201600260 · Cited by 12

5-Hydroxytryptamine 1A and 2B Serotonin Receptors in Neurite Outgrowth: Involvement of Early Growth Response Protein 1

Anelli, T., Cardarelli, S., Ori, M., Nardi, I., Biagioni, S., & Poiana, G. (2013) · Developmental Neuroscience · doi:10.1159/000354423 · Cited by 13

Effects of increasing temperature and aestivation on biogenic amines, signal transduction pathways and metabolic enzyme activities in the sea cucumber (Apostichopus japonicus)

Li, Y., Ding, Y., & Pan, L. (2021) · Marine Biology · doi:10.1007/s00227-021-03981-1 · Cited by 11

Tandospirone prevents stress-induced anxiety-like behavior and visceral hypersensitivity by suppressing theta oscillation enhancement via 5-HT1A receptors in the anterior cingulate cortex in rats

Zhan, T., Dong, Z., Yi, L., Zhang, Y., Sun, H., Zhang, H.-Q., Wang, J., Chen, Y., Huang, Y., & Xu, S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.922750 · Cited by 10

The association between 5-HT1A binding and temporal lobe epilepsy: A meta-analysis of molecular imaging studies

Cai, L., Xu, Z., Luo, H., He, Q., Diao, L., Gui, X., & Wei, L. (2023) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2023.109354 · Cited by 10

TREK-1 inhibition promotes synaptic plasticity in the prelimbic cortex

de Oliveira, J. F., Higa, G. S. V., Viana, F. J. C., Cruvinel, E., Carlos-Lima, E., Borges, F. S., Zampieri, T. T., Rebello, F. P., Ulrich, H., & Pasquale, R. D. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114652 · Cited by 11

Psychedelics in the Treatment of Neurologic and Psychiatric Disorders: Coincidence or a New Point of View

Lashgari, N., Khalaji, M., Rana, P., Badrabadi, F., Rahnama, M., Nasoori, H., Roudsari, N. M., Nia, M. M. K., & Shafaroodi, H. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05097-9 · Cited by 10

Down‐regulation of HTR1A‐modulated ACC activation contributes to stress‐induced visceral hyperalgesia in rats

Yi, L., Sun, H., Zhang, H., Chen, Y., Zhou, L., Xuan, L., Zhan, T., Jiang, Y., & Xu, S. (2019) · Neurogastroenterology & Motility · doi:10.1111/nmo.13620 · Cited by 10

Repeated fluoxetine treatment induces transient and long-term astrocytic plasticity in the medial prefrontal cortex of normal adult rats

Song, T., Chen, W., Chen, X., Zhang, H., Zou, Y., Wu, H., Lin, F., Ren, L., Kang, Y., & Lei, H. C. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110252 · Cited by 10

Design, synthesis, and behavioral evaluation of dual-acting compounds as phosphodiesterase type 10A (PDE10A) inhibitors and serotonin ligands targeting neuropsychiatric symptoms in dementia

Zagórska, A., Bucki, A., Partyka, A., Jastrzębska‐Więsek, M., Siwek, A., Głuch‐Lutwin, M., Mordyl, B., Jaromin, A., Walczak, M., Wesołowska, A., et al. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114218 · Cited by 10

[18F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT1A receptors in humans

Courault, P., Lancelot, S., Costes, N., Colom, M., Bars, D. L., Redouté, J., Gobert, F., Dailler, F., Isal, S., Iecker, T., et al. (2023) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-022-06103-1 · Cited by 10

Region- and receptor-specific effects of chronic social stress on the central serotonergic system in mice

Carneiro-Nascimento, S., Powell, W., Uebel, M., Buerge, M., Sigrist, H., Patterson, M., Pryce, C. R., & Opacka‐Juffry, J. (2021) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2020.11.001 · Cited by 15

Serotonin and vasovagal syncope

Alsaleh, M., Talati, A., Raj, S. R., & Sheldon, R. S. (2024) · Clinical Autonomic Research · doi:10.1007/s10286-024-01052-1 · Cited by 9

Transient Adenosine Modulates Serotonin Release Indirectly in the Dorsal Raphe Nuclei

Shrestha, K., & Venton, B. J. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00687 · Cited by 8

5-HT1A receptors mediate the analgesic effect of rosavin in a mouse model of oxaliplatin-induced peripheral neuropathic pain

Li, D., Park, S., Lee, K., Jang, D. S., & Kim, S. K. (2021) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2021.25.5.489 · Cited by 8

Ligand-directed trafficking of receptor stimulus

Chilmończyk, Z., Bojarski, A. J., & Sylte, I. (2014) · Pharmacological Reports · doi:10.1016/j.pharep.2014.06.006 · Cited by 10

Neonatal hypoxia impairs serotonin release and cognitive functions in adult mice

Lee, K. K. Y., Chattopadhyaya, B., do Nascimento, A. S. F., Moquin, L., Rosa‐Neto, P., Amilhon, B., & Cristo, G. D. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106465 · Cited by 7

Sleep drive, not total sleep amount, increases seizure risk

Cuddapah, V. A., Hsu, C. T., Sirias, F. V., Li, Y., Shah, H. M., Saul, C., Killiany, S. L., Guevara, C., Shon, J. H., Yue, Z., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62311-x · Cited by 10

Neural signaling mechanisms in depression: bridging classical monoamine hypotheses, animal models, and emerging antidepressant strategies

Yamamoto, M., Hirakata, H., & Toda, K. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1777975 · Cited by 11

Cell Signaling by Tryptophan Catabolism

Torrelli-Diljohn, A., Kulkarni, B., & Vitturi, D. A. (2026) · Biochemistry · doi:10.1021/acs.biochem.6c00179 · Cited by 7

Development of New Methods Needs Proper Evaluation—Benchmarking Sets for Machine Learning Experiments for Class A GPCRs

Leśniak, D., Podlewska, S., Jastrzȩbski, S., Sieradzki, I., Bojarski, A. J., & Tabor, J. (2019) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.9b00689 · Cited by 7

Antinociceptive effects of the antidepressant phenelzine are mediated by context-dependent inhibition of neuronal responses in the dorsal horn.

Potter, L. E., Doolen, S., Mifflin, K. A., Tenório, G., Baker, G., Taylor, B., & Kerr, B. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.04.047 · Cited by 6

The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia

Han, D., Shi, S., & Luo, H. (2019) · Journal of Integrative Neuroscience · doi:10.31083/j.jin.2019.03.186 · Cited by 7

Exploring the impact of a high-fat diet on the serotonin signaling in gut-brain axis

Gray, T., Fasina, Y. O., Harrison, S. H., Chang, E. M., Chang, A. Y., Maldonado-Devincci, A., & Han, J. (2025) · Nutritional Neuroscience · doi:10.1080/1028415x.2025.2539320 · Cited by 7

Gene expression changes in conjunctival cells associated with contact lens wear and discomfort

Calderón‐García, A. Á., Nieto, L. V., Sandonís, C. V., la Rosa, A. L., Blanco‐Vázquez, M., Fernández, I., García‐Vázquez, C., Arroyo, C. A.-D., González-García, M. J., & Enríquez‐de‐Salamanca, A. (2023) · The Ocular Surface · doi:10.1016/j.jtos.2023.12.004 · Cited by 6

8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury.

Mao, Z., Song, Z., Li, G., Lv, W., Zhao, X., Li, B., Feng, X., & Chen, Y. (2013) · PubMed Central · doi:10.3969/j.issn.1673-5374.2013.02.005 · Cited by 6

Growth-inhibition of cell lines derived from B cell lymphomas through antagonism of serotonin receptor signaling

Kolan, S. S., Lidström, T., Mediavilla, T., Dernstedt, A., Degerman, S., Hultdin, M., Björk, K., Marcellino, D. J., & Forsell, M. N. E. (2019) · Scientific Reports · doi:10.1038/s41598-019-40825-x · Cited by 6

Serotonergic modulation of excitatory synapse development and plasticity

Chang, V. N., Ogelman, R., Vargas, R. S., & Oh, W. C. (2026) · Molecules and Cells · doi:10.1016/j.mocell.2026.100346 · Cited by 5

Influence of 5-HT2A receptor function on anxiety-like behavior induced by a combination treatment with doxorubicin and cyclophosphamide in rats

Tabuchi, H., Kitamura, Y., Ushio, S., Kan, S., Wada, Y., Sumiyoshi, Y., Izushi, Y., Miyazaki, I., Asanuma, M., & Sendo, T. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05979-5 · Cited by 5

Agitation: Neurobiology and current management guidelines

Miller, C. W. T., Rullo, M., Remmen, S. V., & Mahmood, S. (2024) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2024.11.068 · Cited by 5

Serotonin and aggression

Tricklebank, M. D., & Petrinovic, M. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813323-1.00009-8 · Cited by 5

The role of serotonin in modulating common waxbill behaviour

Saldanha, B. C., Silva, P. A., Maximino, C., Cardoso, G. C., Trigo, S., & Soares, M. C. (2023) · Behavioral Ecology and Sociobiology · doi:10.1007/s00265-023-03316-8 · Cited by 5

Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques

Voisin, D. A., Wakeford, A. G. P., Nye, J. A., Mun, J.-Y., Jones, S. R., Locke, J. L., Huhman, K. L., Wilson, M. E., Albers, H. E., & Michopoulos, V. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173362 · Cited by 5

Establishment of an Animal Model of Depression: The Serotonin Transporter Knockout Rat

Kidwell, M. (2019) · doi:10.26686/wgtn.17135999.v1 · Cited by 5

Neurogenesis and neuroplasticity activities of natural products: therapeutic potential in Alzheimer’s disease

Shaheen, A. M., Mousa, M. H. A., Hindam, M. O., El‐Dessouki, A. M., Fahim, S. A., Hal, D. M., Ahmed, S., El‐Shiekh, R. A., & Khalifa, H. O. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1863841 · Cited by 4

Behavioural and neurochemical alterations following acute inflammation induced by intraperitoneal and intratracheal injection with lipopolysaccharide in mice

Izushi, Y., Tanaka, S., Ueda, T., Ushio, S., Tasaka, Y., Miyazaki, I., Asanuma, M., & Kitamura, Y. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03423-x · Cited by 4

Piperine improves learning deficit through modulation of Wnt/β-catenin signaling pathway: Involvement of the dorsal hippocampus serotonin-1A receptors

Ghasemi, A., Saadinezhad, A., Halalkhor, S., Sadeghi, F., Hosseini, S. M., Karami, M., & Hosseinzadeh, S. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177922 · Cited by 3

5-HT1A Receptor Agonist Treatment Partially Ameliorates Rett Syndrome Phenotypes in mecp2-Null Mice by Rescuing Impairment of Neuron Transmission and the CREB/BDNF Signaling Pathway

Dai, H., Kitami, Y., Goto, Y., & Itoh, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214025 · Cited by 4

The alteration of serotonergic markers in the amygdala and raphe nuclei of oestrogen receptor β knock‐out female mice

Kalinowski, D. A., & Bogus-Nowakowska, K. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16580 · Cited by 5

Tandospirone prevents anesthetic-induced respiratory depression through 5-HT1A receptor activation in rats

Song, M., Huang, M.-Z., Tao, W.-J., Yong, Z., & Su, R. (2025) · Scientific Reports · doi:10.1038/s41598-024-84440-x · Cited by 4

Ventral tegmental area serotonin 5-HT1A receptors and corticolimbic cFos/BDNF/GFAP signaling pathways mediate dextromethorphan/morphine anti-allodynia

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Sleepiness, not total sleep amount, increases seizure riskPreprint

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Kim, M. S., Han, J. E., Kong, C. H., Park, K., Min, H. S., Lee, Y. S., Lee, W. H., Jung, S. Y., Bae, S. K., Lee, J. Y., et al. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111559 · Cited by 2

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Zhang, L., Pang, J., Feng, Q., Hao, J., Gu, X., Jiang, X., Yang, S., Wei, W., & Wu, R. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115554 · Cited by 2

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Mageed, S. S. A., Mangoura, S. A., Nassar, N. N., Moawad, H., & Kamel, A. S. E. D. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115681 · Cited by 1

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Engin, A. B., & Engin, A. (2026) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2026.100575 · Cited by 1

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Sampson, M. M., Gschweng, K. M. M., Hardcastle, B. J., Bonanno, S. L., Sizemore, T. R., Arnold, R. C., Gao, F., Dacks, A. M., Frye, M. A., & Krantz, D. E. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/619759 · Cited by 1

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Hu, Y., Elefteriou, K., Falls, Z., & Samudrala, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.24.684257 · Cited by 1

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Joaquim, H. P. G. (2012) · doi:10.11606/d.5.2012.tde-19032012-090928

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