The diverse functions of GAPDH: Views from different subcellular compartments

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Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

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Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

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S Phase Activation of the Histone H2B Promoter by OCA-S, a Coactivator Complex that Contains GAPDH as a Key Component

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GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

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Sequence-Specific Binding of Transfer RNA by Glyceraldehyde-3-Phosphate Dehydrogenase

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Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH

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Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation

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Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM

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A perillyl alcohol-conjugated analog of 3-bromopyruvate without cellular uptake dependency on monocarboxylate transporter 1 and with activity in 3-BP-resistant tumor cells

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PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH

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A quest for cytocompatible metal organic frameworks in non-viral gene therapy: Relevance of zeolitic imidazolate framework-8

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Membrane skeletal association and post‐translational allosteric regulation of Toxoplasma gondii GAPDH1

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Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose–phosphate pathways in embryonic heart

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Energy Metabolism in the Brain

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Rhodotorula sp. as a promising host for microbial cell factories

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Dual RNA sequencing of group B Streptococcus-infected human monocytes reveals new insights into host–pathogen interactions and bacterial evasion of phagocytosis

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Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel,Ictidomys tridecemlineatus

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Nitric oxide production is not required for dihydrosphingosine-induced cell death in tobacco BY-2 cells

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Heterogeneous Nuclear Ribonucleoproteins and Their Interactors Are a Major Class of Deregulated Proteins in Anaplastic Astrocytoma: A Grade III Malignant Glioma

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Prediction of potential drivers connecting different dysfunctional levels in lung adenocarcinoma via a protein–protein interaction network

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GAPDH-targeted therapy – A new approach for secondary damage after traumatic brain injury on rats

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Early response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom

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High Pressure Stress Response: Involvement of NMDA Receptor Subtypes and Molecular Markers

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Proteomic analysis of protein composition of rat hippocampus exposed to morphine for 10 days; comparison with animals after 20 days of morphine withdrawal

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Protein Signature in Saliva of Temporomandibular Disorders Myalgia

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Neurons undergo pathogenic metabolic reprogramming in models of familial ALS

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Free Radical Scavenging Activity: Antiproliferative and Proteomics Analyses of the Differential Expression of Apoptotic Proteins in MCF-7 Cells Treated with Acetone Leaf Extract ofDiospyros lycioides(Ebenaceae)

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Retrospective Proteomic Screening of 100 Breast Cancer Tissues

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Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase

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Glyceraldehyde-3-phosphate dehydrogenase regulates activation of c-Jun N-terminal kinase under oxidative stress

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High-Temperature Tolerance Protein Engineering through Deep Evolution

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Early signs of neurodegenerative diseases: Possible mechanisms and targets for Golgi stress

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Tianeptine Enhances Energy-related Processes in the Hippocampal Non-synaptic Mitochondria in a Rat Model of Depression

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Catalysis of nitrite generation from nitroglycerin by glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

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Sulfur mustard induced nuclear translocation of glyceraldehyde-3-phosphate-dehydrogenase (GAPDH)

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Paradoxical Inhibition of Glycolysis by Pioglitazone Opposes the Mitochondriopathy Caused by AIF Deficiency

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Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins

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Exploring the Role of Glycolytic Enzymes PFKFB3 and GAPDH in the Modulation of Aβ and Neurodegeneration and Their Potential of Therapeutic Targets in Alzheimer’s Disease

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Beyond glycolysis: multifunctional roles of glyceraldehyde-3-phosphate dehydrogenases in plants

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Age and sex-specific changes in mitochondrial quality control in skeletal and cardiac muscle

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Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts

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Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome

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Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells

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Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors

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Exposure of a specific pleioform of multifunctional glyceraldehyde 3-phosphate dehydrogenase initiates CD14-dependent clearance of apoptotic cells

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Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells

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GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury

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Detection of Thiol Modifications by Hydrogen Sulfide

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GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites

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Visualizing mitochondrial heme flow through GAPDH in living cells and its regulation by NO

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Respiration defects limit serine synthesis required for lung cancer growth and survival

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S-Nitrosylation Regulates Cell Survival and Death in the Central Nervous System

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Understanding the response of Desulfovibrio desulfuricans ATCC 27774 to the electron acceptors nitrate and sulfate - biosynthetic costs modulate substrate selection

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Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer

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Newfound Coding Potential of Transcripts Unveils Missing Members of Human Protein Communities

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Huntingtin Interacting Proteins and Pathological Implications

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Identification of Appropriate Reference Genes for Normalizing miRNA Expression in Citrus Infected by Xanthomonas citri subsp. citri

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Central Metabolism in Mammals and Plants as a Hub for Controlling Cell Fate

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Validation of reference genes for the normalization of the RT-qPCR in peripheral blood mononuclear cells of septic patients

Song, R., He, S., Wu, Y., Chen, W., Song, J., Zhu, Y., Chen, H., Wang, Q., Wang, S., Tan, S., et al. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e15269 · Cited by 11

Glycolytic enzymes in non-glycolytic web: functional analysis of the key players

Malla, A., Gupta, S., & Sur, R. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-023-01213-5 · Cited by 12

Multi-omics analysis reveals GAPDH posttranscriptional regulation of IFN-γ and PHGDH as a metabolic checkpoint of microglia polarization

Yang, S., Yuan, Z., Zhu, Y., Liang, C., Chen, Z., Zhang, J., & Leng, L. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.01.009 · Cited by 11

Multi-dimensional bio mass cytometry: simultaneous analysis of cytoplasmic proteins and metabolites on single cells

Qin, S., Zhang, X., Zhang, Y., Miao, D., Wei, W., & Bai, Y. (2025) · Chemical Science · doi:10.1039/d4sc05055j · Cited by 12

Proteomic Analysis Identifies Potential Markers for Chicken Primary Follicle Development

Wadood, A. A., Wang, J., Pu, L., Shahzad, Q., Waqas, M., Liu, X., Xie, L., Yu, L., Chen, D., Akhtar, R. W., et al. (2021) · Animals · doi:10.3390/ani11041108 · Cited by 11

Oxidative Stress in the Early Stage of Psychosis

Ventriglio, A., Bellomo, A., Favale, D., Bonfitto, I., Vitrani, G., Dario, D. S., Cuozzo, E., Ilaria, D. G., Pettorruso, M., Perna, G., et al. (2021) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026621666210701105839 · Cited by 12

Characteristics and functions of glyceraldehyde 3-phosphate dehydrogenase S-nitrosylation during controlled aging of elm and Arabidopsis seeds

Zeng, M., He, Y., Gao, X., Wang, Y., Deng, S., Ye, T., Wang, X., & Xue, H. (2021) · Journal of Experimental Botany · doi:10.1093/jxb/erab322 · Cited by 11

Glyceraldehyde-3-Phosphate Dehydrogenase Facilitates Macroautophagic Degradation of Mutant Huntingtin Protein Aggregates

Chaudhary, S., Dhiman, A., Dilawari, R., Chaubey, G. K., Talukdar, S., Modanwal, R., Patidar, A., Malhotra, H., Raje, C. I., & Raje, M. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02532-5 · Cited by 11

Deciphering crucial genes in multiple sclerosis pathogenesis and drug repurposing: A systems biology approach

Dadashkhan, S., Mirmotalebisohi, S. A., Poursheykhi, H., Sameni, M., Ghani, S., Abbasi, M., Kalantari, S., & Zali, H. (2023) · Journal of Proteomics · doi:10.1016/j.jprot.2023.104890 · Cited by 11

Switching of colony morphology and adhesion activity ofTrichosporon asahiiclinical isolates

Ichikawa, T., Yoshiyama, N., Ohgane, Y., & Ikeda, R. (2015) · Medical Mycology · doi:10.1093/mmy/myv089 · Cited by 11

PARP-1 is required for retrieval of cocaine-associated memory by binding to the promoter of a novel gene encoding a putative transposase inhibitor

Lax, E., Friedman, A., Massart, R., Barnea, R., Abraham, L., Cheishvili, D., Zada, M., Ahdoot, H. L., Bareli, T., Warhaftig, G., et al. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.119 · Cited by 12

Changes in renal gene expression associated with induced ochratoxicosis in chickens: activation and deactivation of transcripts after varying durations of exposure

Zeferino, C. P., Wells, K. D., Moura, A. S. A. M. T., Rottinghaus, G. E., & Ledoux, D. R. (2016) · Poultry Science · doi:10.3382/ps/pew419 · Cited by 10

MAP1203 Promotes Mycobacterium avium Subspecies paratuberculosis Binding and Invasion to Bovine Epithelial Cells

Everman, J. L., Danelishvili, L., Flores, L. G., & Bermudez, L. E. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00217 · Cited by 11

A transcriptomic analysis based on aberrant methylation levels revealed potential novel therapeutic targets for nasopharyngeal carcinoma

Lyu, M., Yi, X., Huang, Z., Chen, Y., Ai, Z., Liang, Y., Feng, Q., & Xiang, Z. (2022) · Annals of Translational Medicine · doi:10.21037/atm-21-6628 · Cited by 11

Enhanced Proinflammatory Cytokine Production and Immunometabolic Impairment of NK Cells Exposed to Mycobacterium tuberculosis and Cigarette Smoke

Rao, Y., Gai, X., Le, Y., Xiong, J., Liu, Y., Zhang, X., Wang, J., Cao, W., & Sun, Y. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.799276 · Cited by 11

rs9390123 and rs9399451 influence the DNA repair capacity of lung cancer by regulating PEX3 and PHACTR2‑AS1 expression instead of PHACTR2

Shi, Q., Shi, Q.-N., Xu, J.-W., Wang, H., Li, Y.-J., Zhang, X., Fu, Y.-H., Tian, R.-H., Jiang, R., Liu, C., et al. (2022) · Oncology Reports · doi:10.3892/or.2022.8270 · Cited by 11

Spatial perspectives in the redox code—Mass spectrometric proteomics studies of moonlighting proteins

Pinto, G., Radulović, M., & Godovac‐Zimmermann, J. (2016) · Mass Spectrometry Reviews · doi:10.1002/mas.21508 · Cited by 10

R eduction of GAPDH in lenses of P arkinson's disease patients: A possible new biomarker

Klettner, A., Tholey, A., Wiegandt, A., Richert, E., Nölle, B., Deuschl, G., Roider, J. B., & Schneider, S. A. (2016) · Movement Disorders · doi:10.1002/mds.26863 · Cited by 11

The Peculiar Glycolytic Pathway in Hyperthermophylic Archaea: Understanding Its Whims by Experimentation In Silico

Zhang, Y., Kouril, T., Snoep, J. L., Siebers, B., Barberis, M., & Westerhoff, H. V. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18040876 · Cited by 11

Counteracting the Ramifications of UVB Irradiation and Photoaging with Swietenia macrophylla King Seed

Mahendra, C. K., Abidin, S. A. Z., Htar, T. T., Chuah, L., Khan, S. U., Ming, L. C., Tang, S. Y., Pusparajah, P., & Goh, B. H. (2021) · Molecules · doi:10.3390/molecules26072000 · Cited by 11

Exogenous Melatonin Alleviates the Inhibitory Effect of NaHCO3 on Tomato Growth by Regulating the Root pH Value and Promoting Plant Photosynthesis

Yang, Y., Guan, S., Jiang, X., Li, M., Wei, S., & Diao, M. (2023) · Agronomy · doi:10.3390/agronomy13112777 · Cited by 10

Selection and stability validation of reference gene candidates for transcriptional analysis in Rousettus aegyptiacus

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